PDGFR
PDGFR (platelet-derived growth factor receptor) inhibitors are compounds that block the signaling of PDGFR, a receptor involved in cell growth, proliferation, and angiogenesis. PDGFR plays a significant role in the development of the blood vessels that supply tumors. Inhibiting PDGFR can therefore prevent angiogenesis, making these inhibitors valuable in cancer therapy. At CymitQuimica, we provide a selection of high-quality PDGFR inhibitors to support your research in oncology, vascular biology, and angiogenesis.
Found 127 products of "PDGFR"
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Masitinib mesylate
CAS:Masitinib mesylate (AB-1010 mesylate) is a selective and orally bioavailable c-Kit inhibitor (IC50 of 200 nM,540/800 nM,510 nM for human recombinant c-Kit;Formula:C29H34N6O4S2Purity:97.67% - 98.44%Color and Shape:SolidMolecular weight:594.75Dovitinib lactate
CAS:Dovitinib lactate (TKI-258 lactate)(TKI258) lactate is a potent inhibitor of fibroblast growth factor receptor 3 (FGFR3) (IC50 :5 nM).Formula:C24H27FN6O4Purity:99.54% - 99.77%Color and Shape:SolidMolecular weight:482.51Ref: TM-T7104
5mg51.00€10mg79.00€25mg129.00€50mg213.00€100mg358.00€200mg535.00€500mg843.00€1mL*10mM (DMSO)57.00€TAK-593
CAS:TAK-593 is an effective VEGFR and PDGFR family inhibitor (IC50s: 3.2, 0.95, 1.1, 4.3, and 13 nM for VEGFR1, VEGFR2, VEGFR3, PDFGRα, and PDFGRβ, respectively).Formula:C23H23N7O3Purity:99.37%Color and Shape:SolidMolecular weight:445.47Ref: TM-T16975
2mg42.00€5mg62.00€10mg96.00€25mg182.00€50mg284.00€100mg409.00€200mg575.00€1mL*10mM (DMSO)73.00€Crenolanib
CAS:Crenolanib (ARO 002) is an orally bioavailable type III tyrosine kinases inhibitor of PDGFRα/β and FLT3 (IC50s: 11, 3.2, and 4 nM).Formula:C26H29N5O2Purity:98.40% - 99.73%Color and Shape:SolidMolecular weight:443.54Tandutinib
CAS:Tandutinib (CT53518) (MLN518, CT53518), an effective FLT3 antagonist (IC50: 0.22 μM), can also inhibit c-Kit and PDGFR, 15-20 fold higher potency for FLT3Formula:C31H42N6O4Purity:99.45% - ≥98%Color and Shape:White SolidMolecular weight:562.7ON123300
CAS:ON123300 is a potent and multi-targeted kinase inhibitor for CDK4/Ark5/PDGFRβ/FGFR1/RET/Fyn (IC50: 3.9/5/26/26/9.2/11 nM).Formula:C24H27N7OPurity:99.53% - 99.7%Color and Shape:SolidMolecular weight:429.52Orantinib
CAS:Orantinib (NSC 702827) , a excellent effective against PDGFR autophosphorylation with Ki of 8 nM, also highly inhibits Flk-1 and FGFR1 trans-phosphorylation.Formula:C18H18N2O3Purity:98.92% - 99.52%Color and Shape:SolidMolecular weight:310.35Amuvatinib
CAS:Amuvatinib (MP470) is an orally bioavailable synthetic carbothioamide with potential antineoplastic activity.Formula:C23H21N5O3SPurity:99.38% - >99.99%Color and Shape:SolidMolecular weight:447.51SU4984
CAS:SU4984 is a cell-permeable, ATP-competitive and reversible inhibitor of the fibroblast growth factor receptor 1 (FGFR1).Formula:C20H19N3O2Purity:97.20%Color and Shape:SolidMolecular weight:333.38JI-101
CAS:JI-101 (CGI-1842) is an oral multi-kinase inhibitor that targets VEGFR-2, PDGFR-β, and EphB4.Formula:C22H20BrN5O2Purity:99.41% - 99.97%Color and Shape:SolidMolecular weight:466.33Ilorasertib
CAS:Ilorasertib (ABT-348) inhibits Aurora kinases A/B/C & RET, PDGFRβ, Flt1 (IC50: 1-120 nM).Formula:C25H21FN6O2SPurity:96.17% - 97.49%Color and Shape:SolidMolecular weight:488.54Dovitinib lactate hydrate
CAS:Dovitinib lactate hydrate (TKI258) is the Lactate of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit).Formula:C24H27FN6O4Purity:99.82%Color and Shape:SolidMolecular weight:482.51Imatinib
CAS:Imatinib (STI571) is a multi-targeted receptor tyrosine kinase inhibitor that selectively inhibits the kinase activities of BCR/ABL, v-Abl, PDGFR, and c-kitFormula:C29H31N7OPurity:99.42% - 99.94%Color and Shape:Off White PowderMolecular weight:493.6Telatinib
CAS:Telatinib (Bay 57-9352) inhibits VEGFR2/3, c-Kit, PDGFRα with IC50s: 6 nM, 4 nM, 1 nM, 15 nM.Formula:C20H16ClN5O3Purity:97.61% - 99.81%Color and Shape:SolidMolecular weight:409.83Cediranib
CAS:Cediranib (AZD2171) is a potent KDR tyrosine kinase inhibitor (IC50 < 1nM), also targets Flt1/4, PDGFRβ, c-Kit, and more selective for VEGFR.Formula:C25H27FN4O3Purity:97.21% - 99.94%Color and Shape:SolidMolecular weight:450.51Ref: TM-T2500
2mg39.00€5mg59.00€10mg87.00€25mg129.00€50mg168.00€100mg240.00€200mg439.00€500mg703.00€1mL*10mM (DMSO)65.00€Tyrphostin AG1296
CAS:Tyrphostin AG1296 (Tyrphostin AG 1296) is an inhibitor of PDGFR with IC50 of 0.3-0.5 μM, no activity to EGFR.Formula:C16H14N2O2Purity:99.94% - >99.99%Color and Shape:SolidMolecular weight:266.29Ref: TM-T6711
2mg40.00€5mg58.00€10mg90.00€25mg180.00€50mg279.00€100mg411.00€200mg585.00€1mL*10mM (DMSO)81.00€Methylnissolin
CAS:Methylnissolin (3-Hydroxy-9,10-dimethoxyptercarpan) is derived from Astragalus and has antibacterial and anti-cancer effects.Formula:C17H16O5Purity:99.68% - 99.98%Color and Shape:SolidMolecular weight:300.31Linifanib
CAS:Linifanib (AL-39324) (ABT-869) is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR (IC50: 4 nM), CSF-1R (IC50: 3 nM), Flt-1/3 (IC50: 3/4 nM) andFormula:C21H18FN5OPurity:98% - 98.24%Color and Shape:SolidMolecular weight:375.4Ref: TM-T2514
5mg48.00€10mg80.00€25mg119.00€50mg178.00€100mg259.00€200mg477.00€500mg772.00€1mL*10mM (DMSO)50.00€Regorafenib monohydrate
CAS:Regorafenib Monohydrate is a novel oral multikinase inhibitor with IC50 values of 13, 4.2, 46, 22, 7, 1.5, 2.5, 28, 19 nM for VEGFR1, murine VEGFR2, murineFormula:C21H17ClF4N4O4Purity:99.69%Color and Shape:SolidMolecular weight:500.83Ref: TM-T1792L
5mg35.00€10mg48.00€25mg69.00€50mg88.00€100mg140.00€200mg207.00€500mg348.00€1mL*10mM (DMSO)58.00€GW786034B
CAS:Pazopanib HCl (Votrient) inhibits VEGFR1-3, PDGFR, FGFR, c-Kit, c-Fms with IC50 range 10-146 nM in cell-free assays.Formula:C21H23N7O2S·HClPurity:99.87%Color and Shape:SolidMolecular weight:473.98
