c-Met/HGFR
c-Met/HGFR inhibitors target the Hepatocyte Growth Factor Receptor (c-Met), a tyrosine kinase involved in cellular processes such as growth, motility, and morphogenesis. c-Met signaling is implicated in cancer progression, metastasis, and resistance to therapies. Inhibiting c-Met can disrupt tumor growth and spread, making these inhibitors valuable in cancer research. At CymitQuimica, we offer c-Met/HGFR inhibitors to support your research in oncology, metastasis, and targeted cancer therapies.
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MET/PDGFRA-IN-2
MET/PDGFRA-IN-2 (compound 8h) serves as an inhibitor of MET and PDGFRA proteins, promoting apoptosis in …
Formula:
C29H29N7O
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
491.59
Ref: TM-T78844
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Tyrosine kinase inhibitor
CAS:1021950-26-4
Tyrosine kinase inhibitor is a tyrosine kinase inhibitor used in combination with fragmenting aromatic nitrogen …
Formula:
C31H31FN6O5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
586.61
Ref: TM-T17184
| 50mg | To inquire | ||
| 100mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024
PF-04217903 methanesulfonate
CAS:956906-93-7
PF-04217903 methanesulfonate is a potent ATP-competitive inhibitor of c-Met kinase (Ki of 4.8 nM for …
Formula:
C20H20N8O4S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
468.49
Ref: TM-T12417
| 2mg | 53.00 € | ||
| 5mg | 84.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
SYN1143
CAS:913376-84-8
SYN1143 (AMG-1) strongly inhibits RON & c-Met with IC50s: 9 & 4 nmol/L.
Formula:
C31H29FN4O5
Purity:
98.86%
Color and Shape:
Solid
Molecular weight:
556.58
Ref: TM-T8409
| 1mg | 41.00 € | ||
| 5mg | 88.00 € | ||
| 10mg | 120.00 € | ||
| 25mg | 186.00 € | ||
| 50mg | 279.00 € | ||
| 100mg | 414.00 € | ||
| 1mL*10mM (DMSO) | 95.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
S49076
CAS:1265965-22-7
S49076 is a novel, potent inhibitor of MET, AXL/MER, and FGFR1/2/3, blocking cellular phosphorylation of …
Formula:
C22H22N4O4S
Purity:
95.35% - 97.4%
Color and Shape:
Solid
Molecular weight:
438.5
Ref: TM-T3274
| 1mg | 46.00 € | ||
| 2mg | 62.00 € | ||
| 5mg | 82.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 167.00 € | ||
| 50mg | 301.00 € | ||
| 100mg | 549.00 € | ||
| 1mL*10mM (DMSO) | 92.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
DS-1205
CAS:1855860-24-0
DS-1205: AXL kinase inhibitor (IC50=1.3 nM), also targets MER, MET, TRKA (IC50s: 63, 104, 407 …
Formula:
C41H42FN5O7
Purity:
99.28%
Color and Shape:
Solid
Molecular weight:
735.8
Ref: TM-T9123
| 1mg | 104.00 € | ||
| 5mg | 252.00 € | ||
| 10mg | 367.00 € | ||
| 25mg | 683.00 € | ||
| 50mg | 913.00 € | ||
| 1mL*10mM (DMSO) | 281.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
Capmatinib 2HCl
CAS:1197376-85-4
Capmatinib 2HCl (INC-280 2HCl), a c-MET inhibitor, is potent (IC50 = 0.13 nM), highly specific, …
Formula:
C23H19Cl2FN6O
Purity:
100%
Color and Shape:
Solid
Molecular weight:
485.34
Ref: TM-T4260
| 1mg | 43.00 € | ||
| 2mg | 55.00 € | ||
| 5mg | 71.00 € | ||
| 10mg | 87.00 € | ||
| 25mg | 146.00 € | ||
| 50mg | 258.00 € | ||
| 100mg | 430.00 € | ||
| 500mg | 976.00 € | ||
| 1mL*10mM (DMSO) | 97.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
SGX-523
CAS:1022150-57-7
SGX-523 is a selective Met inhibitor (IC50: 4 nM), no inhibitory to Abl, BRAFV599E, p38α, …
Formula:
C18H13N7S
Purity:
100% - 99.6%
Color and Shape:
Solid
Molecular weight:
359.41
Ref: TM-T2293
| 1mg | 52.00 € | ||
| 2mg | 66.00 € | ||
| 5mg | 95.00 € | ||
| 10mg | 138.00 € | ||
| 25mg | 272.00 € | ||
| 50mg | 439.00 € | ||
| 100mg | 648.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
BMS-794833
CAS:1174046-72-0
BMS-794833 is a potent ATP competitive inhibitor of Met/VEGFR2; a prodrug of BMS-817378.
Formula:
C23H15ClF2N4O3
Purity:
98% - 99.69%
Color and Shape:
Solid
Molecular weight:
468.84
Ref: TM-T2419
| 1mg | 41.00 € | ||
| 2mg | 57.00 € | ||
| 5mg | 92.00 € | ||
| 10mg | 152.00 € | ||
| 25mg | 296.00 € | ||
| 50mg | 533.00 € | ||
| 100mg | 754.00 € | ||
| 1mL*10mM (DMSO) | 94.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
Tepotinib hydrochloride(1 : x)
CAS:1103508-80-0
Tepotinib hydrochloride(1 : x) is an orally bioavailable, mesenchymal-epithelial transition (MET) TKI developed mainly for …
Formula:
C29H29ClN6O2
Purity:
99.81%
Color and Shape:
Liquid
Molecular weight:
529.04
Ref: TM-T9601
| 1mg | 143.00 € | ||
| 5mg | 312.00 € | ||
| 10mg | 465.00 € | ||
| 25mg | 741.00 € | ||
| 50mg | 1,054.00 € | ||
| 1mL*10mM (DMSO) | 400.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
XL092
CAS:2367004-54-2
XL092 (JUN04542) is an Axl Mer cMet KDR inhibitor for the treatment of Axl and …
Formula:
C29H25FN4O5
Purity:
99.51%
Color and Shape:
Solid
Molecular weight:
528.53
Ref: TM-T9052
| 2mg | 35.00 € | ||
| 5mg | 51.00 € | ||
| 10mg | 79.00 € | ||
| 25mg | 132.00 € | ||
| 50mg | 208.00 € | ||
| 100mg | 346.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
SCR-1481B1
CAS:1174161-86-4
SCR-1481B1 (c-Met inhibitor 2) has activity against cancers dependent on Met activation and also has …
Formula:
C32H40ClF2N6O13P
Purity:
98.07%
Color and Shape:
Solid
Molecular weight:
821.12
Ref: TM-T5349
| 1mg | 38.00 € | ||
| 2mg | 49.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 118.00 € | ||
| 25mg | 206.00 € | ||
| 50mg | 344.00 € | ||
| 100mg | 510.00 € | ||
| 1mL*10mM (DMSO) | 107.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
Amuvatinib
CAS:850879-09-3
Amuvatinib (MP470) is an orally bioavailable synthetic carbothioamide with potential antineoplastic activity.
Formula:
C23H21N5O3S
Purity:
98.48% - 99.54%
Color and Shape:
Solid
Molecular weight:
447.51
Ref: TM-T2516
| 1mg | 52.00 € | ||
| 2mg | 67.00 € | ||
| 5mg | 90.00 € | ||
| 10mg | 145.00 € | ||
| 25mg | 257.00 € | ||
| 50mg | 411.00 € | ||
| 100mg | 519.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
PHA-665752
CAS:477575-56-7
PHA-665752 is an effective, specific and ATP-competitive c-Met inhibitor (IC50: 9 nM), >50-fold selectivity for …
Formula:
C32H34Cl2N4O4S
Purity:
97.01% - 99.35%
Color and Shape:
Solid
Molecular weight:
641.61
Ref: TM-T6128
| 5mg | 64.00 € | ||
| 10mg | 90.00 € | ||
| 25mg | 176.00 € | ||
| 50mg | 273.00 € | ||
| 100mg | 455.00 € | ||
| 1mL*10mM (DMSO) | 93.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
Crizotinib hydrochloride
CAS:1415560-69-8
Crizotinib hydrochloride (PF-02341066 hydrochloride) is a novel inhibitor of anaplastic lymphoma kinase and c-Met(IC50s of …
Formula:
C21H23Cl3FN5O
Purity:
99.67%
Color and Shape:
Solid
Molecular weight:
486.8
Ref: TM-T8399
| 5mg | 36.00 € | ||
| 10mg | 52.00 € | ||
| 25mg | 81.00 € | ||
| 50mg | 98.00 € | ||
| 100mg | 135.00 € | ||
| 200mg | 168.00 € | ||
| 500mg | 222.00 € | ||
| 1mL*10mM (DMSO) | 59.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
PF-04217903
CAS:956905-27-4
MET Tyrosine Kinase Inhibitor PF-04217903 is an orally bioavailabe, small-molecule tyrosine kinase inhibitor with potential …
Formula:
C19H16N8O
Purity:
98.41% - 98.55%
Color and Shape:
Solid
Molecular weight:
372.38
Ref: TM-T2676
| 1mg | 38.00 € | ||
| 2mg | 49.00 € | ||
| 5mg | 73.00 € | ||
| 10mg | 95.00 € | ||
| 25mg | 169.00 € | ||
| 50mg | 282.00 € | ||
| 100mg | 512.00 € | ||
| 1mL*10mM (DMSO) | 79.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
SAR125884 hydrochlorid (1116743-46-4(free base))
CAS:1116743-46-4
SAR125844 is a potent and selective MET kinase inhibitor with a favorable preclinical toxicity profile,(IC50=4.2 …
Formula:
C25H23FN8O2S2·HCl
Purity:
97.95%
Color and Shape:
Solid
Molecular weight:
587
Ref: TM-T5677
| 1mg | 37.00 € | ||
| 5mg | 59.00 € | ||
| 10mg | 88.00 € | ||
| 25mg | 182.00 € | ||
| 50mg | 269.00 € | ||
| 100mg | 381.00 € | ||
| 200mg | 547.00 € | ||
| 1mL*10mM (DMSO) | 98.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
JNJ-38877605
CAS:943540-75-8
JNJ-38877605 is an ATP-competitive c-Met inhibitor (IC50: 4 nM), 600-fold selective for c-Met than 200 …
Formula:
C19H13F2N7
Purity:
97.04% - 98.27%
Color and Shape:
Solid
Molecular weight:
377.35
Ref: TM-T6095
| 5mg | 37.00 € | ||
| 10mg | 55.00 € | ||
| 25mg | 88.00 € | ||
| 50mg | 142.00 € | ||
| 1mL*10mM (DMSO) | 40.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
Merestinib
CAS:1206799-15-6
Merestinib (LY2801653) is an orally available, small molecule inhibitor of the proto-oncogene c-Met (Ki: 2 …
Formula:
C30H22F2N6O3
Purity:
95% - 99.56%
Color and Shape:
Solid
Molecular weight:
552.53
Ref: TM-T3455
| 1mg | 49.00 € | ||
| 2mg | 71.00 € | ||
| 5mg | 106.00 € | ||
| 10mg | 145.00 € | ||
| 25mg | 255.00 € | ||
| 50mg | 426.00 € | ||
| 100mg | 607.00 € | ||
| 500mg | 1,239.00 € | ||
| 1mL*10mM (DMSO) | 126.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
MGCD-265 analog
CAS:875337-44-3
Glesatinib, an oral tyrosine kinase inhibitor, targets c-Met and VEGFR2 with IC50s of 29 nM …
Formula:
C26H20FN5O2S2
Purity:
98.06% - 98.68%
Color and Shape:
Solid
Molecular weight:
517.6
Ref: TM-T6351
| 2mg | 35.00 € | ||
| 5mg | 51.00 € | ||
| 10mg | 82.00 € | ||
| 25mg | 159.00 € | ||
| 50mg | 246.00 € | ||
| 100mg | To inquire | ||
| 1mL*10mM (DMSO) | 60.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
