Autophagy
Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.
Found 1424 products of "Autophagy"
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Pinosylvin
CAS:<p>Pinosylvin (5-Styrylresorcinol) induces autophagy via AMPK activation. Pinosylvin is likely to act as a pro-angiogenic factor.</p>Formula:C14H12O2Purity:99.89% - 99.91%Color and Shape:SolidMolecular weight:212.24Berbamine dihydrochloride
CAS:<p>Berbamine dihydrochloride (Berbamine), a natural compound derived from the Berberis amurensis plant, has been shown to exhibit antitumor activity in several Ys.</p>Formula:C37H42Cl2N2O6Purity:95% - 99.99%Color and Shape:SolidMolecular weight:681.65Isosorbide Mononitrate
CAS:<p>Isosorbide Mononitrate (Corangin) is a Nitrate Vasodilator, dilating the blood vessels so as to reduce the blood pressure.</p>Formula:C6H9NO6Purity:98.16%Color and Shape:Isosorbide-5-Mononitrate Is A Crystalline Solid It Is Very Flammable And May Be Toxic By IngestionMolecular weight:191.14Entinostat
CAS:<p>Entinostat (MS-275) is an HDAC class I with oral activity. Entinostat has antitumor activity. Cost-effective and quality-assured.</p>Formula:C21H20N4O3Purity:98% - 99.74%Color and Shape:SolidMolecular weight:376.41CCT128930 hydrochloride
CAS:<p>CCT128930 hydrochloride: Potent AKT inhibitor (IC50=6 nM), 28x selective over PKA, 20x over p70S6K, induces cell cycle arrest & DNA damage.</p>Formula:C18H21Cl2N5Purity:98.55%Color and Shape:SolidMolecular weight:378.3Gartanin
CAS:<p>Gartanin enhances androgen receptor degradation and has neuroprotective effects by boosting HO-1, AMPK, SIRT1, and PGC-1α pathways.</p>Formula:C23H24O6Purity:99.64% - 99.85%Color and Shape:SolidMolecular weight:396.43Lucanthone hydrochloride
CAS:<p>Lucanthone hydrochloride is a novel acridine derivative which supresses autophagic degradation and triggers apoptosis in colon cancer cells.</p>Formula:C20H25ClN2OSColor and Shape:SolidMolecular weight:376.94PTC-209 hydrobromide
CAS:<p>PTC-209 hydrobromide (PTC-209 HBr) is the hydrobromide salt of PTC-209, which is a potent and selective BMI-1 inhibitor with IC50 of 0.5 μM, and results in</p>Formula:C17H13Br2N5OS·HBrPurity:99.91%Color and Shape:SolidMolecular weight:576.1Autogramin-1
CAS:<p>Autogramin-1 potently inhibits starvation-induced autophagy with IC50 of 0.17 μM.</p>Formula:C23H27N5O5SPurity:97.69% - 99.25%Color and Shape:SolidMolecular weight:485.56XL388
CAS:<p>XL388 is a highly effective, specifc, ATP-competitive inhibitor of mTOR ( IC50: 9.9 nM), 1000-fold selectivity than the closely related PI3K kinases.</p>Formula:C23H22FN3O4SPurity:99.39% - 99.53%Color and Shape:SolidMolecular weight:455.5NSC 185058
CAS:<p>NSC 185058 is an inhibitor of ATG4B, a major cysteine protease. It also can attenuate the autophagic activity.</p>Formula:C11H9N3SPurity:99.27%Color and Shape:SolidMolecular weight:215.27PF-543 hydrochloride
CAS:<p>PF-543 hydrochloride (PF-543) inhibits SphK1 with a K(i) of 3.6 nM, is sphingosine-competitive and is more than 100-fold selective for SphK1 over the SphK2</p>Formula:C27H32ClNO4SPurity:98.9% - 99.93%Color and Shape:SolidMolecular weight:502.1URMC-099
CAS:<p>URMC-099: oral, brain-accessible MLK/LRRK2 inhibitor; IC50 – MLK1/2/3/DLK: 19/42/14/150 nM, LRRK2: 11 nM.</p>Formula:C27H27N5Purity:99.32% - 99.98%Color and Shape:SolidMolecular weight:421.54Autocamtide-2-related inhibitory peptide
CAS:<p>Autocamtide-2-related inhibitory peptide is a highly specific and potent inhibitor of CaMKII with an IC50 of 40 nM.</p>Formula:C64H116N22O19Purity:>99.99%Color and Shape:SolidMolecular weight:1497.74PF-06447475
CAS:<p>PF-06447475 is a highly effective, specific, brain penetrant LRRK2 inhibitor with IC0 of 3/11 nM for wild type LRRK2 and G2019S LRRK2 respectively.</p>Formula:C17H15N5OPurity:98.61% - 99.62%Color and Shape:SolidMolecular weight:305.33Onjisaponin B
CAS:<p>Onjisaponin B induces autophagy via the AMPK-mTOR signaling pathway, increases the NGF level and accelerates both the removal of mutant huntingtin and A53T α±-</p>Formula:C75H112O35Purity:99.20% - 99.972%Color and Shape:SolidMolecular weight:1573.67A-867744
CAS:<p>A-867744 is an effective and selective type II positive allosteric modulator of the α7 nAChR (EC50: 1.0 μM).</p>Formula:C20H19ClN2O3SPurity:95.66%Color and Shape:SolidMolecular weight:402.89Cucurbitacin E
CAS:<p>Cucurbitacin E, from Cucumic melo, inhibits cyclin B1/CDC2, and has neuroprotective, anti-proliferative, anti-cancer, and pain relief properties.</p>Formula:C32H44O8Purity:98.88% - 99.87%Color and Shape:SolidMolecular weight:556.69TA-01
CAS:<p>TA-01 is a potent CK1 and p38 MAPK inhibitor, with IC50s of 6.4 nM, 6.8 nM, 6.7 nM for CK1ε, CK1δ and p38 MAPK, respectively.</p>Formula:C20H12F3N3Purity:99.55% - 99.94%Color and Shape:SolidMolecular weight:351.32Glucosamine sulfate
CAS:<p>Glucosamine sulfate (D-Glucosaminesulfate) was extracted from synthetic product;Store the product in sealed, cool and dry condition.</p>Formula:C6H13NO5·H2SO4Purity:99.64%Color and Shape:White CrystalMolecular weight:277.25
