Autophagy
Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.
Found 1457 products of "Autophagy"
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Retro-2
CAS:<p>Retro-2 (2-{[(5-methyl-2-thienyl)methylene]amino}) is a plant toxin ricin inhibitor, it protects HeLa cells against Ricin, Stx1 and Stx2.</p>Formula:C19H16N2OSPurity:98.15%Color and Shape:SolidMolecular weight:320.41PHA-665752
CAS:<p>PHA-665752 is an effective, specific and ATP-competitive c-Met inhibitor (IC50: 9 nM), >50-fold selectivity for c-Met than STKs or RTKs.</p>Formula:C32H34Cl2N4O4SPurity:97.05% - 98.82%Color and Shape:SolidMolecular weight:641.61Tacrolimus monohydrate
CAS:<p>Tacrolimus monohydrate (LCP-Tacro) is a macrolide from the culture broth of a strain of Streptomyces tsukubaensis, binds to FKBP to form a complex.</p>Formula:C44H71NO13Purity:97.07% - 98.05%Color and Shape:SolidMolecular weight:822.05Dorsomorphin
CAS:Dorsomorphin (BML-275) is an AMPK inhibitor (Ki=109 nM) that is selective and ATP-competitive.Formula:C24H25N5OPurity:98% - 99.06%Color and Shape:SolidMolecular weight:399.49Glucosamine sulfate
CAS:Glucosamine sulfate (D-Glucosaminesulfate) was extracted from synthetic product;Store the product in sealed, cool and dry condition.Formula:C6H13NO5·H2SO4Purity:99.64%Color and Shape:White CrystalMolecular weight:277.25Lucanthone hydrochloride
CAS:Lucanthone hydrochloride is a novel acridine derivative which supresses autophagic degradation and triggers apoptosis in colon cancer cells.Formula:C20H25ClN2OSColor and Shape:SolidMolecular weight:376.94Cucurbitacin E
CAS:Cucurbitacin E, from Cucumic melo, inhibits cyclin B1/CDC2, and has neuroprotective, anti-proliferative, anti-cancer, and pain relief properties.Formula:C32H44O8Purity:98.88% - 99.87%Color and Shape:SolidMolecular weight:556.69Vistusertib
CAS:Vistusertib (AZD2014) is an orally bioavailable inhibitor of the mammalian target of rapamycin (mTOR) with potential antineoplastic activity.Formula:C25H30N6O3Purity:97.08% - 99.06%Color and Shape:SolidMolecular weight:462.54Paris saponin VII
CAS:<p>Paris saponin VII (Dioscini) shows inhibitory effects on cell proliferation.</p>Formula:C51H82O21Purity:99.51% - 99.63%Color and Shape:SolidMolecular weight:1031.18DBEQ
CAS:<p>DBEQ (JRF 12) is a selective, potent, reversible, and ATP-competitive p97 inhibitor.</p>Formula:C22H20N4Purity:98.93% - ≥95%Color and Shape:SolidMolecular weight:340.42UBCS039
CAS:UBCS039 is the first synthetic Sirt6 activator(EC50 : 38 μM)Formula:C16H13N3Purity:98.31%Color and Shape:SolidMolecular weight:247.29Ataluren
CAS:Ataluren (PTC124) is a novel, orally administered drug that targets nonsense mutations.Formula:C15H9FN2O3Purity:99.16% - 99.84%Color and Shape:SolidMolecular weight:284.24SRT 1720
CAS:<p>SRT 1720 is a selective activator of human SIRT1 (EC1.5: 0.16 μM) and is >230-fold less potent for SIRT2 and SIRT3.</p>Formula:C25H23N7OSPurity:98.84%Color and Shape:SolidMolecular weight:469.56BAY 11-7082
CAS:BAY 11-7082 (BAY 11-7821) is an NF-κB inhibitor that inhibits TNFα-induced IκBα phosphorylation (IC50=10 μM).Formula:C10H9NO2SPurity:98% - 99.92%Color and Shape:SolidMolecular weight:207.25L-779450
CAS:L-779450, an effective, ATP-competitive Raf kinase inhibitor (IC50: 10 nM) , displays >7, >30 and >70-fold selectivity over p38α, GSK3β and Lck respectively.Formula:C20H14ClN3OPurity:≥95%Color and Shape:SolidMolecular weight:347.8Gemcitabine hydrochloride
CAS:Gemcitabine hydrochloride (LY 188011 hydrochloride) is a synthetic cytosine nucleoside derivative and an inhibitor of DNA synthesis.Formula:C9H11F2N3O4·HClPurity:99.28% - 99.98%Color and Shape:White Crystalline Granular OdorlessMolecular weight:299.66BL-918
CAS:BL-918 is a potent activator of UNC-51-like kinase 1 (ULK1) with an EC50 of 24.14 nM.Formula:C23H15F8N3OSPurity:99.4% - 99.89%Color and Shape:SolidMolecular weight:533.44TPEN
CAS:<p>TPEN (TPEDA) is a specific cell-permeable heavy metal chelator.</p>Formula:C26H28N6Purity:98% - 99.72%Color and Shape:White Crystalline PowderMolecular weight:424.54RSVA405
CAS:RSVA405 is an AMPK activator (EC50 = 1 μM), and is STAT3 inhibitorFormula:C17H20N4O2Purity:99.30%Color and Shape:SolidMolecular weight:312.37Zebularine
CAS:Zebularine (4-Deoxyuridine) is a DNA methylation inhibitor.Formula:C9H12N2O5Purity:99.04% - >99.99%Color and Shape:SolidMolecular weight:228.2
