Autophagy
Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.
Found 1504 products of "Autophagy"
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AMG PERK 44
CAS:AMG PERK 44 is a PERK inhibitor that induces autophagy.AMG PERK 44 inhibits GCN2 and B-Raf and can be used in cancer research.Formula:C34H29ClN4O2Purity:98.8% - 99.81%Color and Shape:SolidMolecular weight:561.07XRK3F2
CAS:XRK3F2 inhibits p62-ZZ, counters MM's Runx2 suppression in vitro, and prompts bone growth and remodeling in vivo with tumors.Formula:C23H24ClF2NO3Purity:98.91% - 99.12%Color and Shape:SolidMolecular weight:435.89MAPK13-IN-1
CAS:MAPK13-IN-1 is a potent MAPK13 (p38δ) inhibitor (IC50: 620 nM).Formula:C20H23N5O2Purity:99.62%Color and Shape:SolidMolecular weight:365.43Ref: TM-T11943
1mg94.00€2mg137.00€5mg222.00€10mg334.00€25mg578.00€50mg838.00€100mg1,224.00€500mg2,448.00€1mL*10mM (DMSO)245.00€ITX5061
CAS:ITX5061 is a type II inhibitor of p38 MAPK and scavenger receptor B1 (SRB1) antagonist for the study of hepatitis C virus infection.Formula:C30H38ClN3O7SPurity:98.35%Color and Shape:SolidMolecular weight:620.16Ref: TM-T15603
1mg192.00€5mg485.00€10mg713.00€25mg1,198.00€50mg1,693.00€100mg2,250.00€1mL*10mM (DMSO)642.00€Mavorixafor
CAS:Mavorixafor (AMD-070) is an effective and selective antagonist of CXCR4, with an IC50 value of 13 nM against CXCR4 125I-SDF binding.Formula:C21H27N5Purity:98.56%Color and Shape:SolidMolecular weight:349.47Ref: TM-TQ0174
1mg39.00€2mg50.00€5mg84.00€10mg123.00€25mg215.00€50mg348.00€100mg557.00€1mL*10mM (DMSO)92.00€Ezurpimtrostat hydrochloride
CAS:Ethacrysta hydrochloride (GNS561 hydrochloride) is a PPT1 inhibitor with antifibrotic properties and may be used in studies of hepatocellular carcinoma.Formula:C25H32Cl2N4Purity:99.84%Color and Shape:SolidMolecular weight:459.45NUCC-390
CAS:NUCC-390, a novel small-molecule CXCR4 receptor agonist, selectively induces CXCR4 receptor internalization while acting antagonistically to AMD3100.Formula:C23H33N5OPurity:97.08%Color and Shape:SolidMolecular weight:395.54Ref: TM-T12269
1mg109.00€5mg260.00€10mg409.00€25mg730.00€50mg1,018.00€100mg1,369.00€200mg1,783.00€1mL*10mM (DMSO)268.00€Acetazolamide sodium
CAS:Acetazolamide sodium (OT-302 sodium) is a potent carbonic anhydrase (CA) IX inhibitor used for indications such as epilepsy and altitude sickness.Formula:C4H5N4NaO3S2Purity:99.71% - 99.87%Color and Shape:SolidMolecular weight:244.23Elubrixin
CAS:Elubrixin (SB-656933) inhibits neutrophil CD11b upregulation (IC50 of 260.7 nM) and shape change (IC50 of 310.5 nM).Formula:C17H17Cl2FN4O4SPurity:98.65% - 99.78%Color and Shape:SolidMolecular weight:463.31Ref: TM-T11179
1mg109.00€5mg235.00€10mg349.00€25mg532.00€50mg745.00€100mg999.00€200mg1,333.00€1mL*10mM (DMSO)253.00€Dactolisib Tosylate
CAS:Dactolisib Tosylate (BEZ235 Tosylate) is a dual kinase inhibitor that targets PI3K and mTOR.Formula:C37H31N5O4SPurity:99.91%Color and Shape:SolidMolecular weight:641.74Apostatin-1
CAS:Apostatin-1 (Apt-1) is a novel TRADD inhibitor. Apostatin-1 can bind to a pocket on the N-terminal TRAF2 binding domain of TRADD.Formula:C19H27N3OSPurity:99.31%Color and Shape:SolidMolecular weight:345.5Ref: TM-T9079
1mg34.00€2mg49.00€5mg74.00€10mg113.00€25mg222.00€50mg358.00€100mg530.00€500mg1,153.00€1mL*10mM (DMSO)82.00€Atg4B-IN-2
CAS:Atg4B-IN-2 is an Atg4B inhibitor with anticancer activity that inhibits Atg4B and PLA2 and resists the anticancer activity of resistant prostate cancer drugs.Formula:C21H30O3Purity:98.86%Color and Shape:SolidMolecular weight:330.46Laduviglusib trihydrochloride
CAS:Laduviglusib trihydrochloride, a GSK-3α/β inhibitor (IC50: 10/6.7 nM), activates Wnt/β-catenin signaling and induces autophagy.Formula:C22H20Cl5N8Purity:99.34%Color and Shape:SolidMolecular weight:573.71FMK 9a
CAS:FMK 9a is an irreversible inhibitor of ATG4B with IC50 values of 80 and 73 nM in the TR-FRET and cellular-based LRA assays.Formula:C23H21FN2O3Purity:98.97%Color and Shape:SolidMolecular weight:392.42Ref: TM-T15303
1mg105.00€5mg260.00€10mg385.00€25mg620.00€50mg879.00€100mg1,153.00€200mg1,584.00€1mL*10mM (DMSO)269.00€Nilotinib hydrochloride
CAS:Nilotinib HCl (AMN-107 HCl), an oral Bcr-Abl inhibitor, targets neuroinflammation, cognitive issues, and chronic myelogenous leukemia.Formula:C28H23ClF3N7OPurity:99.98%Color and Shape:SolidMolecular weight:565.98CP-312
CAS:CP-312 activates antioxidant defense, induces HMOX1, and shields human iPSC-derived cardiomyocytes from oxidative stress.Formula:C16H12ClN3OS2Purity:99.89%Color and Shape:SolidMolecular weight:361.87Cysmethynil
CAS:Cysmethynil is an indole-based Icmt inhibitor with antitumor activity, induces cell cycle arrest in G1 phase, and can be used for the study of solid tumors.Formula:C25H32N2OPurity:99%Color and Shape:SolidMolecular weight:376.53Ref: TM-T36082
1mg44.00€2mg57.00€5mg93.00€10mg133.00€25mg260.00€50mg416.00€100mg670.00€500mg1,341.00€Cosalane
CAS:Cosalane (NSC 658586) is an HIV replication inhibitor and an inhibitor of chemokine receptor 7 (CCR7) signalling in humans and mice.Formula:C45H60Cl2O6Purity:99.53% - 99.78%Color and Shape:SolidMolecular weight:767.86Tin-protoporphyrin IX dichloride
CAS:Tin-protoporphyrin IX inhibits HO-1, enhancing chemo efficacy in mouse PDAC.Formula:C34H32Cl2N4O4SnPurity:98%Color and Shape:SolidMolecular weight:750.26CHIR-99021 HCl
CAS:CHIR-99021 HCl is a selective GSK-3α/β inhibitor (IC50: 10/6.7 nM), 500x selective over other kinases, boosts Wnt pathway, and enhances stem cell renewal.Formula:C22H19Cl3N8Purity:98.07% - 98.14%Color and Shape:SolidMolecular weight:501.8Ref: TM-T2310L
1mg34.00€2mg49.00€5mg73.00€10mg90.00€25mg155.00€50mg227.00€100mg442.00€200mg640.00€500mg973.00€1mL*10mM (DMSO)81.00€IT1t dihydrochloride
CAS:IT1t dihydrochloride inhibits CXCL12/CXCR4 interaction with IC50 of 2.1 nM. IT1t dihydrochloride is an antagonist of CXCR4.Formula:C21H36Cl2N4S2Purity:99.91%Color and Shape:SolidMolecular weight:479.57Ref: TM-T11693L
2mg34.00€5mg50.00€10mg92.00€25mg166.00€50mg289.00€100mg420.00€200mg583.00€1mL*10mM (DMSO)56.00€Rosolutamide
CAS:Rosolutamide (ALZ-003) is a curcumin analog, an Nrf1 and Nrf2 activator.Formula:C28H32O6Purity:95.48% - 99.15%Color and Shape:SolidMolecular weight:464.55Cytarabine hydrochloride
CAS:Cytarabine hydrochloride (Ara-C hydrochloride) is a nucleoside analog that causes S phase cell cycle arrest and inhibits DNA polymerase.
Formula:C9H14ClN3O5Purity:98.46%Color and Shape:White PowderMolecular weight:279.68MTK458
CAS:MTK458 (EP-0035985) is a PINK1 activator with antidepressant activity for the study of Parkinson;s disease.Formula:C17H15F3N4Purity:98.36%Color and Shape:SolidMolecular weight:332.32AC-73
CAS:AC-73, an oral CD147 inhibitor, blocks ERK1/2/STAT3/MMP-2 pathway, reducing liver cancer progression and leukemia cell growth.Formula:C21H21NO2Purity:99.36%Color and Shape:SolidMolecular weight:319.4Ref: TM-T14091
1mg50.00€5mg92.00€10mg170.00€25mg289.00€50mg487.00€100mg862.00€500mg1,728.00€1mL*10mM (DMSO)103.00€AZD8797
CAS:AZD8797 (KAND567) is a CX3CR1 antagonist with potential protective effects against neuronal damage and prevents nociceptive hypersensitivity in rats.Formula:C19H25N5OS2Purity:98.73% - 99.68%Color and Shape:SolidMolecular weight:403.56Ref: TM-T14384
1mg80.00€5mg170.00€10mg253.00€25mg442.00€50mg620.00€100mg845.00€1mL*10mM (DMSO)187.00€GC7 Sulfate
CAS:GC7 Sulfate blocks DHS, the sole enzyme activating eIF5A2, thus preventing eIF5A2 activation.Formula:C8H22N4O4SPurity:98.07% - 99.85%Color and Shape:SolidMolecular weight:270.35AZD8309
CAS:AZD8309 is an oral CXCR2 antagonist, curbing neutrophil movement, lowering MPO in lungs/pancreas, and trypsin/elastase activity.
Formula:C15H14F2N4O2S2Purity:98.35% - 99.67%Color and Shape:SolidMolecular weight:384.42Acitretin sodium
CAS:Acitretin sodium is a second-generation, systemic retinoid. It is also has been used in the treatment of psoriasis.Formula:C21H26NaO3Purity:98%Color and Shape:SolidMolecular weight:349.42SLLN-15
CAS:SLLN-15: oral, potent autophagy enhancer; targets macroautophagy in TNBC.Formula:C19H23N7Se2Purity:98%Color and Shape:SolidMolecular weight:507.35Di-N-desethyl amiodarone hydrochloride
CAS:Di-N-desethyl Amiodarone hydrochloride, a metabolite of Amiodarone, functions as a potent inhibitor of the respiratory chain [1].Formula:C21H22ClI2NO3Purity:98%Color and Shape:SolidMolecular weight:625.67SR10067
CAS:SR10067 is a potent, selective and brain penetrant agonist of Rev-Erbβ(IC50 = 160 nM) and Rev-Erbα(IC50 = 170 nM) with anxiolytic activity.Formula:C31H31NO3Purity:99.57%Color and Shape:SolidMolecular weight:465.58Ref: TM-T12998
1mg46.00€5mg84.00€10mg114.00€25mg234.00€50mg348.00€100mg510.00€200mg858.00€1mL*10mM (DMSO)93.00€TIQ-15
CAS:TIQ-15 is an effective and selective CXCR4 antagonist. It has good drug-like properties.Formula:C23H32N4Purity:98%Color and Shape:SolidMolecular weight:364.53Antitumor agent-82
Antitumor agent-82: potent, anti-proliferative, induces autophagy via ATG5/ATG7.Formula:C32H42N6Color and Shape:SolidMolecular weight:510.72Calmidazolium chloride
CAS:Calmidazolium chloride blocks calmodulin, hinders phosphodiesterase (IC50=0.15µM), Ca2+-ATPase (IC50=0.35µM), and can induce cancer cell apoptosis.Formula:C31H23Cl7N2OPurity:98.53%Color and Shape:SolidMolecular weight:687.7Ref: TM-T10667
5mg59.00€10mg93.00€25mg138.00€50mg203.00€100mg304.00€200mg442.00€1mL*10mM (DMSO)90.00€4E2RCat
CAS:4E2RCat is an inhibitor of eIF4E-eIF4G interaction (IC50 = 13.5 μM) and is capable of blocking coronavirus replication as monitored by viral protein expressionFormula:C22H14ClNO4S2Purity:98.44%Color and Shape:SolidMolecular weight:455.93RK-682
CAS:RK-682 is a natural selective inhibitor of protein tyrosine phosphatases (PTPases).Formula:C21H36O5Color and Shape:SolidMolecular weight:368.51Beclin1-ATG14L interaction inhibitor 1
CAS:Beclin1-ATG14L Interaction Inhibitor 1 (COM 19) is a selective inhibitor targeting the specific interaction between Beclin1 and ATG14L.Formula:C23H24N4O5SPurity:98%Color and Shape:SolidMolecular weight:468.53LY2955303
CAS:LY2955303 is an effective and selective antagonist of retinoic acid receptor gamma (RARγ, Ki = 1.09 nM).Formula:C36H42N4O3Purity:98.56% - 99.85%Color and Shape:SolidMolecular weight:578.74AMD-3329 hydrobromide
CAS:AMD-3329 hydrobromide: strong, selective anti-HIV agent, blocks virus replication by targeting CXCR4 co-receptor.Formula:C34H58Br8N8Color and Shape:SolidMolecular weight:1218.13Butylate
CAS:Butylate is a herbicide of thiocarbamate.Formula:C11H23NOSColor and Shape:Less Liquid Which Darkens Upon Exposure To Light Air And Moisture Colorless Liquid Which Darkens Upon Exposure To Light Air And MoistureMolecular weight:217.37USP30 inhibitor 18
CAS:USP30 inhibitor 18 is a selective inhibitor of USP30 (IC50 = 0.02 μM). USP30 inhibitor 18 is able to accelerate mitophagy and increase protein ubiquitination.Formula:C26H28FN3O4SPurity:99.85%Color and Shape:SolidMolecular weight:497.58Ref: TM-T36682
1mg137.00€5mg281.00€10mg447.00€25mg713.00€50mg1,018.00€100mg1,369.00€500mg2,673.00€1mL*10mM (DMSO)309.00€E6130
CAS:E6130 may be effective in the treatment of inflammatory bowel disease and is a highly selective CX3CR1 regulator for oral administration.Formula:C28H37ClF3N3O3Color and Shape:SolidMolecular weight:556.06BPO-27 racemate
CAS:BPO-27 racemate (BPO-27 (racemate)) is an effective CFTR inhibitor with IC50 of 8 nM.Formula:C26H18BrN3O6Purity:97.67% - 98.86%Color and Shape:SolidMolecular weight:548.34Ref: TM-T10591
1mg44.00€5mg111.00€10mg166.00€25mg265.00€50mg388.00€100mg535.00€200mg718.00€1mL*10mM (DMSO)128.00€DCAP
CAS:DCAP, a broad-spectrum antibiotic, disrupts the membranes of both Gram-positive and Gram-negative bacteria. Additionally, it inhibits late-stage autophagy by blocking autophagolysosome maturation and interrupting autophagic flux [1].Formula:C19H22Cl2N2O4Color and Shape:SolidMolecular weight:413.3KN-93 Phosphate
CAS:KN-93 (Phosphate) can competitively block the binding of calmodulin to the corresponding kinase.Cost-effective and quality-assured.Formula:C26H32ClN2O8PSPurity:99.58% - 99.93%Color and Shape:SolidMolecular weight:599.03Ref: TM-T2606
1mg49.00€5mg92.00€10mg137.00€25mg268.00€50mg497.00€100mg718.00€500mg1,431.00€1mL*10mM (DMSO)132.00€Ladarixin Sodium
CAS:Ladarixin Sodium, an Chemokine CXCR antagonist, is used potentially for the treatment of type I diabetes.Formula:C11H12F3NNaO6S2Color and Shape:SolidMolecular weight:398.32EACC
CAS:EACC inhibits Stx17, blocking autophagosome-lysosome fusion, and is a reversible autophagy inhibitor.Formula:C13H11N3O6S2Purity:99.8%Color and Shape:SolidMolecular weight:369.37INT-767
CAS:INT-767 is a highly potent farneson X receptor (FXR)/TGR5 dual agonist that prevents NASH and promotes visceral fat brown lipogenesis and mitochondrial functionFormula:C25H43NaO6SPurity:98%Color and Shape:SolidMolecular weight:494.66(3R,5R)-Rosuvastatin
CAS:(3R,5R)-Rosuvastatin is the (3R,5R)-enantiomer of Rosuvastatin. Rosuvastatin is a competitive HMG-CoA reductase inhibitor (IC50: 11 nM).Formula:C22H28FN3O6SPurity:98%Color and Shape:SolidMolecular weight:481.54
