CymitQuimica logo
DUB

DUB

DUB inhibitors target deubiquitinases, enzymes that remove ubiquitin molecules from proteins, thereby regulating the stability, localization, and activity of proteins within the cell. Deubiquitinases play essential roles in various cellular processes, including cell cycle regulation, DNA repair, and immune responses. Dysregulation of DUB activity is linked to cancer, neurodegenerative disorders, and viral infections. Inhibitors of DUBs can modulate these processes, offering potential therapeutic approaches for these conditions. At CymitQuimica, we provide DUB inhibitors to support your research in protein homeostasis, cancer, and neurobiology.

Found 84 products of "DUB"

Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
products per page.
  • P22074
    Targetmol
    + Info

    P22074

    CAS:
    <p>P22074 is a USP7 inhibitor. It is not an active antagonist like its halogenated related compounds. p22074 has antitumour activity.</p>
    Formula:C12H9NO3S2
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:279.33

    Ref: TM-T28284

  • USP22-IN-1
    Targetmol
    + Info

    USP22-IN-1

    CAS:
    <p>USP22-IN-1 is a ubiquitin-specific peptidase 22 (USP22) inhibitor that can be used to treat proliferative diseases or cancer.</p>
    Formula:C22H18N4
    Purity:98.2%
    Color and Shape:Solid
    Molecular weight:338.41

    Ref: TM-T73151

  • OTUB1/USP8-IN-1
    Targetmol
    + Info

    OTUB1/USP8-IN-1

    CAS:
    <p>OTUB1/USP8-IN-1 is an OTUB1/USP8 inhibitor with anticancer activity for the study of non-small cell lung cancer.</p>
    Formula:C22H16ClFN2O4
    Purity:98.59%
    Color and Shape:Soild
    Molecular weight:426.83

    Ref: TM-T72784

  • USP1-IN-3
    Targetmol
    + Info

    USP1-IN-3

    CAS:
    <p>USP1-IN-3 is a selective inhibitor of USPI that inhibits USPI-UAFI (IC50&lt;30 nM). USP1-IN-3 can be used to study cancer.</p>
    Formula:C27H24F3N7O
    Color and Shape:Solid
    Molecular weight:519.52

    Ref: TM-T63625

  • USP1-IN-5
    Targetmol
    + Info

    USP1-IN-5

    CAS:
    <p>USP1-IN-5 (compound 10) is a potent inhibitor of both USP1, with an IC50 of less than 50 nM, and MDA-MB-436 cells, where it also exhibits an IC50 of less than</p>
    Formula:C27H23F3N8O
    Color and Shape:Solid
    Molecular weight:532.52

    Ref: TM-T79795

  • USP7-IN-12
    Targetmol
    + Info

    USP7-IN-12

    CAS:
    <p>USP7-IN-12 (compound 1) is a potent, orally active inhibitor of Usp7, exhibiting an IC50 of 3.67 nM and demonstrating antiproliferative activity [1].</p>
    Formula:C29H28ClFN4O2S
    Color and Shape:Solid
    Molecular weight:551.07

    Ref: TM-T79164

  • FT206
    Targetmol
    + Info

    FT206

    CAS:
    <p>FT206 is a carboxamide inhibitor of ubiquitin-specific protease[1].</p>
    Formula:C25H29N5OS
    Color and Shape:Solid
    Molecular weight:447.6

    Ref: TM-T36306

  • USP7-IN-1
    Targetmol
    + Info

    USP7-IN-1

    CAS:
    <p>USP7-IN-1 is a selective and reversible ubiquitin-specific protease 7 (USP7) inhibitor (IC50 = 77 μM).</p>
    Formula:C23H24ClN3O3
    Purity:99.82%
    Color and Shape:Solid
    Molecular weight:425.91

    Ref: TM-T13268

  • DUB-IN-7
    Targetmol
    + Info

    DUB-IN-7

    CAS:
    <p>DUB-IN-7 (compound 43), a deubiquitinating enzyme (DUB) inhibitor, has utility in researching diseases driven by aberrant JAK2 activity, including leukemia [1].</p>
    Formula:C17H19N5O
    Color and Shape:Solid
    Molecular weight:309.37

    Ref: TM-T79672

  • FT671
    Targetmol
    + Info

    FT671

    CAS:
    <p>FT671 is a non-covalent and selective inhibitor of USP7 (IC50: 52 nM) It also binds to the USP7 catalytic domain (Kd: 65 nM).</p>
    Formula:C24H23F4N7O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:533.48

    Ref: TM-T12621L

  • USP7-IN-3
    Targetmol
    + Info

    USP7-IN-3

    CAS:
    <p>USP7-IN-3 is a potent and selective allosteric inhibitor of ubiquitin-specific protease 7 (USP7).</p>
    Formula:C29H31F3N6O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:568.59

    Ref: TM-T13269

  • LDN-91946
    Targetmol
    + Info

    LDN-91946

    CAS:
    <p>LDN-91946 is an effective and selective inhibitor of ubiquitin C-terminal hydrolase-L1 (UCH-L1) (Ki = 2.8 μM).</p>
    Formula:C15H10N2O4S
    Purity:97.12%
    Color and Shape:Solid
    Molecular weight:314.32

    Ref: TM-T15729

  • USP30 inhibitor 18
    Targetmol
    + Info

    USP30 inhibitor 18

    CAS:
    <p>USP30 inhibitor 18 is a selective inhibitor of USP30 (IC50 = 0.02 μM). USP30 inhibitor 18 is able to accelerate mitophagy and increase protein ubiquitination.</p>
    Formula:C26H28FN3O4S
    Purity:99.85%
    Color and Shape:Solid
    Molecular weight:497.58

    Ref: TM-T36682

  • USP1-IN-6
    Targetmol
    + Info

    USP1-IN-6

    CAS:
    <p>USP1-IN-6 (Compound 11) functions as a potent USP1 inhibitor, exhibiting an IC50 value of less than 50 nM.</p>
    Formula:C29H27F3N8O
    Color and Shape:Solid
    Molecular weight:560.57

    Ref: TM-T79796

  • CT1113
    Targetmol
    + Info

    CT1113

    CAS:
    <p>CT1113, a potent inhibitor of both USP28 and USP25, effectively reduces MYC levels in vivo and demonstrates anti-tumor efficacy in a mouse pancreatic cancer CDX</p>
    Formula:C25H29N5O2S
    Color and Shape:Solid
    Molecular weight:463.6

    Ref: TM-T79187

  • USP7-IN-13
    Targetmol
    + Info

    USP7-IN-13

    CAS:
    <p>USP7-IN-13 (Compound 101), a USP7 inhibitor, exhibits an IC50 range of 0.2-1 μM and is applicable in researching multiple myeloma [1].</p>
    Formula:C24H28N4O3
    Color and Shape:Solid
    Molecular weight:420.5

    Ref: TM-T84710

  • IMP-1710
    Targetmol
    + Info

    IMP-1710

    CAS:
    <p>IMP-1710 is a selective UCH-L1 inhibitor with an IC50 value of 38 nM in a fluorescence polarization assay.[1]Cost-effective and quality-assured.</p>
    Formula:C23H19N5O
    Purity:99.3%
    Color and Shape:Solid
    Molecular weight:381.43

    Ref: TM-T37591

  • USP7-IN-10
    Targetmol
    + Info

    USP7-IN-10

    CAS:
    <p>USP7-IN-10 is a potent inhibitor of ubiquitin-specific protease 7 (USP7), exhibiting an inhibition concentration half-maximal (IC50) value of 13.39 nM.</p>
    Formula:C26H29ClN4O3S
    Color and Shape:Solid
    Molecular weight:513.05

    Ref: TM-T73136

  • FT709
    Targetmol
    + Info

    FT709

    CAS:
    <p>FT709 is a selective USP9X deubiquitinating enzyme inhibitor (IC50=82 nM) that reduces Makorin and ZNF598 levels, impairing ribosomal quality control pathways.</p>
    Formula:C23H22N4O7S
    Color and Shape:Solid
    Molecular weight:498.51

    Ref: TM-T63375

  • CymitQuimica logo
    Targetmol
    + Info

    FT3967385

    <p>FT3967385: New USP30 inhibitor boosts mitochondrial ubiquitylation via PINK1-PARKIN.</p>
    Formula:C21H19N5O2
    Color and Shape:Solid
    Molecular weight:373.41

    Ref: TM-T61512