DUB
DUB inhibitors target deubiquitinases, enzymes that remove ubiquitin molecules from proteins, thereby regulating the stability, localization, and activity of proteins within the cell. Deubiquitinases play essential roles in various cellular processes, including cell cycle regulation, DNA repair, and immune responses. Dysregulation of DUB activity is linked to cancer, neurodegenerative disorders, and viral infections. Inhibitors of DUBs can modulate these processes, offering potential therapeutic approaches for these conditions. At CymitQuimica, we provide DUB inhibitors to support your research in protein homeostasis, cancer, and neurobiology.
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HBX 41108
CAS:924296-39-9
HBX 41108: non-competitive, reversible USP7 inhibitor; IC50: 424nM; blocks USP7-p53 deubiquitination; IC50: 0.8μM.
Formula:
C13H3ClN4O
Purity:
95.63%
Color and Shape:
Solid
Molecular weight:
266.64
Ref: TM-T21527
| 1mg | 51.00 € | ||
| 2mg | 74.00 € | ||
| 5mg | 111.00 € | ||
| 10mg | 180.00 € | ||
| 25mg | 424.00 € | ||
| 50mg | 627.00 € | ||
| 100mg | 893.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
NSC632839
CAS:157654-67-6
NSC-632839 (Ubiquitin Isopeptidase Inhibitor II) is a nonselective isopeptidase inhibitor, which inhibits USP2 (EC50: 45±4 …
Formula:
C21H22ClNO
Purity:
99.74% - 99.87%
Color and Shape:
Solid
Molecular weight:
339.86
Ref: TM-T3951
| 5mg | 51.00 € | ||
| 10mg | 79.00 € | ||
| 25mg | 150.00 € | ||
| 50mg | 259.00 € | ||
| 100mg | 394.00 € | ||
| 500mg | 894.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
DUB-IN-1
CAS:924296-18-4
DUB-IN-1, with an IC50 value of 0.24 for USP8, is an active inhibitor of ubiquitin-specific …
Formula:
C20H11N5O
Purity:
98.33% - 98.96%
Color and Shape:
Solid
Molecular weight:
337.33
Ref: TM-T11110
| 1mg | 65.00 € | ||
| 5mg | 116.00 € | ||
| 10mg | 183.00 € | ||
| 25mg | 353.00 € | ||
| 50mg | 495.00 € | ||
| 100mg | 652.00 € | ||
| 200mg | 895.00 € | ||
| 1mL*10mM (DMSO) | 128.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
USP7/USP47 inhibitor
CAS:1247825-37-1
USP7/USP47 inhibitor (USP7/47 inhibitor-1) is a selective ubiquitin-specific protease 7/47 (USP7/USP47) inhibitor, with EC50s of …
Formula:
C18H11Cl2N3O3S3
Purity:
97.98% - 98.5%
Color and Shape:
Solid
Molecular weight:
484.4
Ref: TM-T4338
| 1mg | 43.00 € | ||
| 5mg | 92.00 € | ||
| 10mg | 160.00 € | ||
| 25mg | 329.00 € | ||
| 50mg | 547.00 € | ||
| 100mg | 905.00 € | ||
| 500mg | 1,786.00 € | ||
| 1mL*10mM (DMSO) | 99.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
EOAI3402143
CAS:1699750-95-2
EOAI3402143 inhibits Usp9x and Usp24 activity, increases tumor cell apoptosis.
Formula:
C25H28Cl2N4O3
Purity:
98.09%
Color and Shape:
Solid
Molecular weight:
503.42
Ref: TM-T11209
| 1mg | 66.00 € | ||
| 5mg | 144.00 € | ||
| 10mg | 227.00 € | ||
| 25mg | 445.00 € | ||
| 50mg | 717.00 € | ||
| 100mg | 1,064.00 € | ||
| 1mL*10mM (DMSO) | 160.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
USP25/28 inhibitor AZ1
CAS:2165322-94-9
USP25/28 inhibitor AZ1 is a selective, orally active and non-competitive dual ubiquitin-specific protease USP25/28 inhibitor.Cost-effective …
Formula:
C17H16BrF4NO2
Purity:
99.79% - 99.79%
Color and Shape:
Solid
Molecular weight:
422.21
Ref: TM-T7685
| 1mg | 35.00 € | ||
| 5mg | 70.00 € | ||
| 10mg | 97.00 € | ||
| 25mg | 210.00 € | ||
| 50mg | 321.00 € | ||
| 100mg | 472.00 € | ||
| 500mg | 1,035.00 € | ||
| 1mL*10mM (DMSO) | 78.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
P 22077
CAS:1247819-59-5
P 22077 (P22077) is an inhibitor of ubiquitin-specific protease USP7 with EC50 of 8.6 μM. …
Formula:
C12H7F2NO3S2
Purity:
97.9% - 99.58%
Color and Shape:
Solid
Molecular weight:
315.32
Ref: TM-T2424
| 2mg | 38.00 € | ||
| 5mg | 57.00 € | ||
| 10mg | 90.00 € | ||
| 25mg | 164.00 € | ||
| 50mg | 304.00 € | ||
| 100mg | 452.00 € | ||
| 1mL*10mM (DMSO) | 89.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
IU1
CAS:314245-33-5
IU1 是一种可逆的特异性人类 USP14 蛋白酶体抑制剂,可以穿透细胞,IC50为 4.7 μM。
Formula:
C18H21FN2O
Purity:
98% - 99.30%
Color and Shape:
Solid
Molecular weight:
300.37
Ref: TM-T6107
| 5mg | 59.00 € | ||
| 10mg | 84.00 € | ||
| 25mg | 143.00 € | ||
| 50mg | 240.00 € | ||
| 100mg | 425.00 € | ||
| 1mL*10mM (DMSO) | 65.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
P005091
CAS:882257-11-6
P005091 (P5091) is a selective and potent inhibitor of ubiquitin-specific protease 7 (USP7) with EC50 …
Formula:
C12H7Cl2NO3S2
Purity:
99.53% - 99.87%
Color and Shape:
Solid
Molecular weight:
348.22
Ref: TM-T6925
| 2mg | 47.00 € | ||
| 5mg | 69.00 € | ||
| 10mg | 88.00 € | ||
| 25mg | 156.00 € | ||
| 50mg | 256.00 € | ||
| 100mg | 410.00 € | ||
| 1mL*10mM (DMSO) | 74.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
DUB-IN-3
CAS:924296-17-3
DUB-IN-3 is a potent deubiquitinase (USP) enzyme inhibitor and the IC50 for USP8 is 0.56 …
Formula:
C16H9N5O
Purity:
99.34%
Color and Shape:
Solid
Molecular weight:
287.28
Ref: TM-T11112
| 1mg | 137.00 € | ||
| 2mg | 188.00 € | ||
| 5mg | 325.00 € | ||
| 10mg | 465.00 € | ||
| 25mg | 743.00 € | ||
| 50mg | 1,035.00 € | ||
| 100mg | 1,406.00 € | ||
| 500mg | 2,802.00 € | ||
| 1mL*10mM (DMSO) | 341.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
ML364
CAS:1991986-30-1
ML364 is an inhibitor of ubiquitin specific peptidase 2 (USP2) and can be used for …
Formula:
C24H18F3N3O3S2
Purity:
100% - 99.92%
Color and Shape:
Solid
Molecular weight:
517.54
Ref: TM-T3555
| 5mg | 72.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 175.00 € | ||
| 50mg | 279.00 € | ||
| 100mg | 435.00 € | ||
| 500mg | 935.00 € | ||
| 1mL*10mM (DMSO) | 82.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
IU1-248
CAS:2307472-03-1
IU1-248 is a derivative of IU1. IU1-248 is a potent and selective USP14 inhibitor with …
Formula:
C20H23N3O2
Purity:
99.30%
Color and Shape:
Solid
Molecular weight:
337.42
Ref: TM-T9375
| 1mg | 77.00 € | ||
| 5mg | 169.00 € | ||
| 10mg | 264.00 € | ||
| 25mg | 535.00 € | ||
| 50mg | 753.00 € | ||
| 100mg | 1,074.00 € | ||
| 1mL*10mM (DMSO) | 180.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
GNE-6776
CAS:2009273-71-4
GNE-6776 is a selective USP7 inhibitor.
Formula:
C20H20N4O2
Purity:
96.59% - 98.2%
Color and Shape:
Solid
Molecular weight:
348.4
Ref: TM-T4634
| 1mg | 81.00 € | ||
| 5mg | 170.00 € | ||
| 10mg | 273.00 € | ||
| 25mg | 525.00 € | ||
| 50mg | 753.00 € | ||
| 100mg | 1,026.00 € | ||
| 1mL*10mM (DMSO) | 187.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
TCID
CAS:30675-13-9
TCID (UCH-L3 Inhibitor)(IC50=0.6 μM) is a DUB inhibitor of ubiquitin C-terminal hydrolase L3. It has …
Formula:
C9H2Cl4O2
Purity:
99.34%
Color and Shape:
Solid
Molecular weight:
283.92
Ref: TM-T6697
| 2mg | 39.00 € | ||
| 5mg | 57.00 € | ||
| 10mg | 88.00 € | ||
| 25mg | 170.00 € | ||
| 50mg | 220.00 € | ||
| 100mg | 285.00 € | ||
| 1mL*10mM (DMSO) | 62.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
USP28-IN-4
CAS:2931509-15-6
USP28-IN-4 is a USP28 inhibitor with anticancer activity that dose-dependently down-regulates cellular levels of c-Myc …
Formula:
C22H18Cl2N2O3S
Purity:
98.48%
Color and Shape:
Liquid
Molecular weight:
461.36
Ref: TM-T74794
| 1mg | 62.00 € | ||
| 5mg | 133.00 € | ||
| 10mg | 202.00 € | ||
| 25mg | 406.00 € | ||
| 50mg | 645.00 € | ||
| 100mg | 1,017.00 € |
Estimated delivery in United States, on Tuesday 10 Jun 2025
OTUB1/USP8-IN-1
CAS:2858800-98-1
OTUB1/USP8-IN-1 is an OTUB1/USP8 inhibitor with anticancer activity for the study of non-small cell lung …
Formula:
C22H16ClFN2O4
Purity:
98.59%
Color and Shape:
Soild
Molecular weight:
426.83
Ref: TM-T72784
| 1mg | 99.00 € | ||
| 5mg | 235.00 € | ||
| 10mg | 376.00 € | ||
| 25mg | 747.00 € | ||
| 50mg | 1,121.00 € | ||
| 100mg | 1,768.00 € |
Estimated delivery in United States, on Tuesday 10 Jun 2025
USP30 inhibitor 11
CAS:2067332-64-1
USP30 inhibitor 11 (USP30-IN-11) is a USP30 inhibitor that inhibits SVA and can be used …
Formula:
C17H16N6O2S
Purity:
100% - 96.31%
Color and Shape:
Solid
Molecular weight:
368.41
Ref: TM-T13267
| 1mg | 205.00 € | ||
| 5mg | 512.00 € | ||
| 10mg | 753.00 € | ||
| 25mg | 1,121.00 € | ||
| 50mg | 1,549.00 € | ||
| 100mg | 2,080.00 € |
Estimated delivery in United States, on Tuesday 10 Jun 2025
I-138
CAS:2098211-50-6
I-138 is an orally active and reversible inhibitor of USP1-UAF1.I-138 induces mono-ubiquitination of FANCD2 and …
Formula:
C26H23F3N6O
Purity:
99.41%
Color and Shape:
Liquid
Molecular weight:
492.5
Ref: TM-T73560
| 1mg | 188.00 € | ||
| 2mg | 255.00 € | ||
| 5mg | 369.00 € | ||
| 10mg | 597.00 € | ||
| 25mg | 1,121.00 € | ||
| 50mg | 1,700.00 € | ||
| 100mg | 2,205.00 € | ||
| 1mL*10mM (DMSO) | 425.00 € |
Estimated delivery in United States, on Tuesday 10 Jun 2025
SJB3-019A
CAS:2070015-29-9
SJB3-019A is a potent, potent and novel ubiquitin-specific protease 1 (USP1) inhibitor, which promotes ID1 …
Formula:
C16H8N2O3
Purity:
99.75%
Color and Shape:
Solid
Molecular weight:
276.25
Ref: TM-T12926
| 1mg | 94.00 € | ||
| 2mg | 137.00 € | ||
| 5mg | 224.00 € | ||
| 10mg | 339.00 € | ||
| 25mg | 560.00 € | ||
| 50mg | 810.00 € | ||
| 100mg | 1,121.00 € | ||
| 500mg | 2,232.00 € |
Estimated delivery in United States, on Tuesday 10 Jun 2025
P22074
CAS:90680-28-7
P22074 is a USP7 inhibitor. It is not an active antagonist like its halogenated related …
Formula:
C12H9NO3S2
Purity:
100%
Color and Shape:
Solid
Molecular weight:
279.33
Ref: TM-T28284
| 1mg | 200.00 € | ||
| 5mg | 472.00 € | ||
| 10mg | 645.00 € | ||
| 25mg | 905.00 € | ||
| 1mL*10mM (DMSO) | 360.00 € |
Estimated delivery in United States, on Tuesday 10 Jun 2025
