DUB
DUB inhibitors target deubiquitinases, enzymes that remove ubiquitin molecules from proteins, thereby regulating the stability, localization, and activity of proteins within the cell. Deubiquitinases play essential roles in various cellular processes, including cell cycle regulation, DNA repair, and immune responses. Dysregulation of DUB activity is linked to cancer, neurodegenerative disorders, and viral infections. Inhibitors of DUBs can modulate these processes, offering potential therapeutic approaches for these conditions. At CymitQuimica, we provide DUB inhibitors to support your research in protein homeostasis, cancer, and neurobiology.
Found 104 products for "DUB".
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USP7/USP47 inhibitor
CAS:USP7/USP47 inhibitor (USP7/47 inhibitor-1) is a selective ubiquitin-specific protease 7/47 (USP7/USP47) inhibitor, with EC50s of 0.42 μM and 1.0 μM,Formula:C18H11Cl2N3O3S3Purity:98.5% - 98.71%Color and Shape:SolidMolecular weight:484.4Ref: TM-T4338
1mg40.00€1mL*10mM (DMSO)94.00€5mg96.00€10mg152.00€25mg268.00€50mg429.00€100mg703.00€200mg954.00€P005091
CAS:P005091 (P5091) is a selective and potent inhibitor of ubiquitin-specific protease 7 (USP7) with EC50 of 4.2 μM.Formula:C12H7Cl2NO3S2Purity:99.53% - 99.87%Color and Shape:SolidMolecular weight:348.22XL177A
CAS:XL177A is a selective irreversible USP7 inhibitor(IC50 : 0.34 nM). XL177A elicits cancer cell killing through a p53-dependent mechanism.Formula:C48H57ClN8O5Purity:98.75% - 99.49%Color and Shape:Yellow SolidMolecular weight:861.47USP25/28 inhibitor AZ1
CAS:USP25/28 inhibitor AZ1 is a selective, orally active and non-competitive dual ubiquitin-specific protease USP25/28 inhibitor.Cost-effective and quality-assured.Formula:C17H16BrF4NO2Purity:99.81% - 99.86%Color and Shape:White SolidMolecular weight:422.21Ref: TM-T7685
10mgTo inquire25mgTo inquire50mgTo inquire100mgTo inquire1mg34.00€5mg66.00€1mL*10mM (DMSO)73.00€USP7-IN-8
CAS:Benzamide, 4-[6-amino-4-ethyl-5-(4-hydroxyphenyl)-3-pyridinyl]-N-methyl- is a selective ubiquitin-specific protease 7 (USP7) inhibitor with an IC50 of 1.4 μM.Formula:C21H21N3O2Purity:99.31%Color and Shape:SolidMolecular weight:347.41Ref: TM-T9217
1mg46.00€5mg92.00€1mL*10mM (DMSO)100.00€10mg147.00€25mg269.00€50mg389.00€100mg532.00€200mg705.00€SJB2-043
CAS:SJB2-043 is an inhibitor of USP1-UAF1 ( IC50 : 544 nM).Formula:C17H9NO3Purity:98.44%Color and Shape:SolidMolecular weight:275.26VLX1570
CAS:VLX1570 is a competitive inhibitor of proteasome DUB activity with IC50 ranging from 4.2 uM to 8.6 uM. It has potent inhibition for USP14.Formula:C23H17F2N3O6Purity:98.53% - 99.91%Color and Shape:SolidMolecular weight:469.39Ref: TM-T4067
1mg90.00€2mg146.00€5mg245.00€1mL*10mM (DMSO)251.00€10mg385.00€25mg645.00€50mg888.00€100mg1,234.00€ML-323
CAS:ML323 is a reversible and effective USP1-UAF1 inhibitor in a Ub-Rho assay and in orthogonal gel-based assays using K63-linked di-Ub and Ub-PCNA as substrates.Formula:C23H24N6Purity:99.87% - 99.96%Color and Shape:SolidMolecular weight:384.48DUB-IN-3
CAS:DUB-IN-3 is a potent deubiquitinase (USP) enzyme inhibitor and the IC50 for USP8 is 0.56 μM.Formula:C16H9N5OPurity:99.34%Color and Shape:SolidMolecular weight:287.28Ref: TM-T11112
1mg130.00€2mg178.00€5mg309.00€1mL*10mM (DMSO)324.00€10mg442.00€25mg705.00€50mg982.00€100mg1,333.00€500mg2,655.00€GNE-6640
CAS:GNE-6640: non-covalent USP7 inhibitor; IC50s: 0.75 µM (full), 0.43 µM (catalytic), 20.3 µM (USP43), 0.23 µM (Ub-MDM2).Formula:C20H18N4OPurity:98.64%Color and Shape:SolidMolecular weight:330.38Ref: TM-T5461
1mg66.00€2mg96.00€5mg144.00€1mL*10mM (DMSO)158.00€10mg236.00€25mg507.00€50mg730.00€100mg1,018.00€NSC632839
CAS:NSC-632839 (Ubiquitin Isopeptidase Inhibitor II) is a nonselective isopeptidase inhibitor, which inhibits USP2 (EC50: 45±4 μM), USP7 (EC50: 37±1 μM), and SENP2Formula:C21H22ClNOPurity:99.74% - 99.88%Color and Shape:SolidMolecular weight:339.86EOAI3402143
CAS:EOAI3402143 inhibits Usp9x and Usp24 activity, increases tumor cell apoptosis.Formula:C25H28Cl2N4O3Purity:99.6%Color and Shape:SolidMolecular weight:503.42Ref: TM-T11209
1mg63.00€5mg137.00€1mL*10mM (DMSO)152.00€10mg215.00€25mg423.00€50mg680.00€100mg1,009.00€TCID
CAS:TCID (UCH-L3 Inhibitor)(IC50=0.6 μM) is a DUB inhibitor of ubiquitin C-terminal hydrolase L3. It has the 125-fold selectivity to L1.Formula:C9H2Cl4O2Purity:98.87% - 99.34%Color and Shape:SolidMolecular weight:283.92ML364
CAS:ML364 is an inhibitor of ubiquitin specific peptidase 2 (USP2) and can be used for the research of breast cancer.Formula:C24H18F3N3O3S2Purity:99.35% - >99.99%Color and Shape:SolidMolecular weight:517.54USP1-IN-2
CAS:USP1-IN-2 is a potent USP1 inhibitor with potential anti-tumor activity for the study of cancer.Formula:C26H22F4N6OPurity:99.88% - 99.99%Color and Shape:SolidMolecular weight:510.486Ref: TM-T63518
1mg164.00€5mg389.00€1mL*10mM (DMSO)452.00€10mg515.00€25mg783.00€50mg1,054.00€100mg1,423.00€POSH-IN-1
CAS:POSH-IN-1 (Compound 108) is an inhibitor of the POSH polypeptide （e3 ligase) and has antiviral, anticancer, and neurodegenerative disease potential.Formula:C14H8FNO3SPurity:99.29%Color and Shape:SolidMolecular weight:289.28VCPIP1-IN-2
CAS:VCPIP1-IN-1 (Compound 076) is an inhibitor of VCPIP1.Formula:C14H13ClFN3O2Color and Shape:SolidMolecular weight:309.72LCAHA
CAS:LCAHA is a USP2a inhibitor. LCAHA inhibits growth of cyclin D1-dependent cells.Formula:C24H41NO3Color and Shape:SolidMolecular weight:391.59FT827
CAS:FT827 is a covalent inhibitor of USP7 that targets the catalytic center of the autoinhibitory apolipoprotein form of USP7 for cancer research.Formula:C27H28N6O5SPurity:98.76%Color and Shape:White SolidMolecular weight:548.61MF-095
CAS:MF-095 is a control probe for MF-094, which is a potent inhibitor of ubiquitin specific protease 30.Formula:C27H31N3O4SColor and Shape:SolidMolecular weight:493.62
