Endothelin Receptor
Endothelin receptors are GPCRs that mediate the effects of endothelins, potent vasoconstrictor peptides that play a significant role in vascular tone regulation, blood pressure control, and cell proliferation. Endothelin receptor antagonists are used in the treatment of conditions such as pulmonary arterial hypertension and heart failure. These receptors are also important targets in research on cardiovascular diseases and cancer. At CymitQuimica, we offer a selection of high-quality endothelin receptor modulators to support your research in cardiovascular biology, oncology, and vascular physiology.
Found 86 products of "Endothelin Receptor"
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Macitentan
CAS:Macitentan (ACT-064992) is an endothelin receptor antagonist that is used in the therapy of pulmonary arterial hypertension (PAH).Formula:C19H20Br2N6O4SPurity:98% - >99.99%Color and Shape:SolidMolecular weight:588.27Endothelin-2 (49-69), human
CAS:Endothelin-2 (49-69), human (Human endothelin-2) is a 21-amino acid vasoactive peptide that binds to G-protein-linked transmembrane receptors, ET-RA and ET-RB.Formula:C115H160N26O32S4Purity:98.26%Color and Shape:SolidMolecular weight:2546.92Nebentan potassium
CAS:Nebentan potassium (YM598) is an ETA receptor antagonist that inhibits pulmonary arterial hypertension and is used in the study of neurologic diseases.Formula:C24H20KN5O5SPurity:99.05%Color and Shape:SolidMolecular weight:529.61Ref: TM-T36008
1mg52.00€2mg77.00€5mg111.00€10mg177.00€25mg313.00€50mg502.00€100mg680.00€200mg888.00€1mL*10mM (DMSO)133.00€Zibotentan
CAS:Zibotentan (ZD4054) (ZD4054) is a specific Endothelin (ET)A antagonist with IC50 of 21 nM, exhibiting no activity at ETB. Phase 3.Formula:C19H16N6O4SPurity:97.00% - 97.02%Color and Shape:SolidMolecular weight:424.43TBC3711
CAS:TBC3711 is an endothelin receptor modulator. It is used for the research of endothelin-mediated disorders.Formula:C20H21N3O5S2Purity:98%Color and Shape:SolidMolecular weight:447.53ZD-1611
CAS:ZD-1611 is an effective and selective ETA receptor antagonist. It is used for the research of ischemic stroke.Formula:C22H24N4O5SPurity:98%Color and Shape:SolidMolecular weight:456.51CH 141
CAS:CH 141 is a new type of peripheral vasodilator.Formula:C19H21N3OColor and Shape:SolidMolecular weight:307.39ABT-546
CAS:ABT-546 is a potent, selective endothelin ETA receptor antagonist, Ki 0.46 nM for [125I]ET-1 binding.Formula:C30H48N2O6Purity:98%Color and Shape:SolidMolecular weight:532.71BMS-193884
CAS:BMS-193884 is an oral endothelin antagonist for the treatment of congestive heart failure (CHF) and pulmonary arterial hypertension.Formula:C20H17N3O4SColor and Shape:SolidMolecular weight:395.43CI 1020
CAS:endothelin-A receptor (ETA) antagonistFormula:C28H26O9Purity:98%Color and Shape:SolidMolecular weight:506.5PD-156707
CAS:PD-156707 is a selective antagonist of endothelin A receptor.Formula:C28H26NaO9Purity:98%Color and Shape:SolidMolecular weight:529.497WS 009B
CAS:WS 009B is an antagonist of the endothelin receptor.Formula:C24H25NO11SPurity:98%Color and Shape:SolidMolecular weight:535.52Daglutril
CAS:Daglutril is a NEP/ECE inhibitor for treating hypertension, heart failure, and pulmonary issues, blocking big endothelin-1 conversion.Formula:C31H38N2O6Color and Shape:SolidMolecular weight:534.64Atrasentan hydrochloride
CAS:Atrasentan hydrochloride (ABT-627 hydrochloride) is an antagonist of the endothelin receptor(IC50 = 55.1 μM for ETA).Formula:C29H39ClN2O6Purity:99.75%Color and Shape:SolidMolecular weight:547.08Avosentan
CAS:Avosentan（Ro 67-0565; SPP-301） is a potent endothelin receptor (ETA) antagonist.Cost-effective and quality-assured.Formula:C23H21N5O5SPurity:98.31% - 99.47%Color and Shape:SolidMolecular weight:479.51PD-159020
CAS:PD-159020 is a non-selective antagonist of ETA/ETB(hETA and hETB with IC50s of 30 and 50 nM , respectively).Formula:C32H25NO8Purity:98%Color and Shape:SolidMolecular weight:551.54WS 009A
CAS:WS 009A is an antagonist of the endothelin receptor.Formula:C24H25NO10SPurity:98%Color and Shape:SolidMolecular weight:519.52ETA antagonist 1
CAS:ETA antagonist 1 is an antagonist of ETA selective (IC50 of 0.08 μM).Formula:C20H25N3O3SPurity:98%Color and Shape:SolidMolecular weight:387.5Aminaftone
CAS:Aminaftone, a derivative of 4-aminobenzoic acid, inhibits endothelin-1 (ET-1) production and can be used to study hypertension and systemic sclerosis.Formula:C18H15NO4Purity:96.31% - 99.39%Color and Shape:SolidMolecular weight:309.32FR 139317
CAS:highly potent and selective ETA endothelin receptor antagonistFormula:C33H44N6O5Purity:98%Color and Shape:SolidMolecular weight:604.74BMS 182874
CAS:BMS 182874: Oral ETA antagonist, IC50=0.150 μM, Ki=0.055 μM, lowers hypertension in rats.Formula:C17H19N3O3SPurity:99.73%Color and Shape:SolidMolecular weight:345.42Edonentan
CAS:Edonentan is A potent endothelin A (ETA) receptor antagonist that can be used to study heart failure.Formula:C28H32N4O5SPurity:98.07% - 99.6%Color and Shape:SolidMolecular weight:536.64SB-209670
CAS:SB-209670 is a selective endothelin receptor antagonist that inhibits the activity of ET(B) receptors in rat vascular endothelium and vascular smooth muscle.Formula:C29H28O9Purity:98.29% - 99.40%Color and Shape:SolidMolecular weight:520.53Ref: TM-T34541
1mg315.00€5mg745.00€10mg1,018.00€25mg1,431.00€50mg1,783.00€100mg2,250.00€500mg4,410.00€1mL*10mM (DMSO)755.00€Sitaxsentan
CAS:Sitaxsentan (TBC-11251), a selective ETA receptor antagonist, prevents vasoconstriction by blocking endothelin.Formula:C18H15ClN2O6S2Purity:97.99% - 98.71%Color and Shape:SolidMolecular weight:454.9L-749329
CAS:L-749329 is a ligand of ET(A) and ET(B) endothelin receptor.Formula:C28H29NO8SPurity:98%Color and Shape:SolidMolecular weight:539.6Clazosentan
CAS:Clazosentan (Ro 61-1790) is a selective ET_A receptor antagonist that inhibits ET-1 vasoconstriction and prevents cerebral vasospasm.Formula:C25H23N9O6SPurity:95.39% - >99.99%Color and Shape:SolidMolecular weight:577.57Ref: TM-T64084
1mg79.00€5mg178.00€10mg279.00€25mg628.00€50mg1,017.00€100mg1,311.00€200mg1,768.00€1mL*10mM (DMSO)230.00€K-8794
CAS:K-8794 is an orally active and selective endothelin receptor ETB antagonist that can be utilized in cardiovascular disease research.Formula:C36H38N6O6SColor and Shape:SolidMolecular weight:682.789Edonentan hydrate
CAS:Edonentan (BMS 207940) hydrate effectively blocks the endothelin A (ETA) receptor as a potent and selective antagonist, featuring a K i of 10 pM. It exhibits complete (100%) oral bioavailability in rats [1].Formula:C28H34N4O6SColor and Shape:SolidMolecular weight:554.66Diosuxentan
CAS:Diosuxentan is an inhibitor of ETA and is utilized in research pertaining to cardiovascular, renal, and neuronal inflammatory diseases.Formula:C20H21BrN6O7SColor and Shape:SolidMolecular weight:569.39BMS-248360
CAS:BMS-248360: Oral dual hAT1/hETA antagonist with Kis of 10nM & 1.9nM, respectively; treats hypertension.Formula:C36H45N5O5SPurity:98%Color and Shape:SolidMolecular weight:659.84JKC 302
CAS:JKC 302 is an ET-A receptor antagonist that partially inhibits the contraction of tracheal rings in asthmatic rats induced by ET-1.Formula:C30H42N6O6Color and Shape:SolidMolecular weight:582.69Macitentan (n-butyl analogue)
CAS:Macitentan n-butyl analogue, an oral ETA/ETB receptor blocker, may treat IPF and PAH.Formula:C20H21Br2N5O4SPurity:98%Color and Shape:SolidMolecular weight:587.29IRL 2500
CAS:IRL 2500 is an antagonist of Endothelin receptor with IC50s of 1.3 and 94 nM for Endothelin A receptor and Endothelin B receptor.Formula:C36H35N3O4Purity:99.36%Color and Shape:White Crystalline SolidMolecular weight:573.68Tezosentan
CAS:Tezosentan is an antagonist of the endothelin receptor (pA2s: 9.5, 7.7 for ETA and ETB receptors, respectively).Formula:C27H27N9O6SPurity:98%Color and Shape:SolidMolecular weight:605.63BQ-788
CAS:BQ-788 is an ETB receptor antagonist with potential hypertensive activity that inhibits exogenous ET-1-induced elevation of coronary perfusion pressure.Formula:C34H51N5O7Purity:98.81%Color and Shape:SolidMolecular weight:641.8Ref: TM-T10595
1mg137.00€2mg188.00€5mg329.00€10mg472.00€25mg753.00€50mg1,017.00€100mg1,378.00€500mg2,737.00€1mL*10mM (DMSO)360.00€Patecibart
CAS:Patecibart is a humanized immunoglobulin G4-kappa monoclonal antibody that functions as an antagonist to the endothelin receptor A (EDNRA).
Purity:98%Color and Shape:Liquid
