Bombesin Receptor
Bombesin receptors are a group of GPCRs that are activated by bombesin-like peptides, which are involved in regulating gastrointestinal function, energy balance, and cell proliferation. These receptors are of particular interest in cancer research, as they are often overexpressed in certain types of tumors. Bombesin receptor antagonists are studied for their potential as cancer therapeutics. At CymitQuimica, we provide a selection of high-quality bombesin receptor modulators to support your research in oncology, gastrointestinal physiology, and receptor signaling.
Found 35 products of "Bombesin Receptor"
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CD80-IN-3
CAS:CD80-IN-3 is a potent CD80 inhibitor and inhibits CD80/CD28 interaction (Kd: 125 nM; EC50: 630 nM).Formula:C17H10FN3O3Purity:98.08%Color and Shape:SolidMolecular weight:323.28Ref: TM-T10722
1mg75.00€5mg177.00€1mL*10mM (DMSO)195.00€10mg289.00€25mg467.00€50mg647.00€100mg802.00€Ici 216140
CAS:ICI 216140: GRP/bombesin receptor 2 blocker, potent at 2 nM. Reduces amylase at 2 mg/kg and lowers bombesin-induced blood pressure at 1 mM in rats.Formula:C45H65N13O8Color and Shape:SolidMolecular weight:916.08AMTG-DA1
AMTG-DA1 is a ligand for the gastrin-releasing peptide receptor (GRPR), and it can be utilized in cancer research.Formula:C101H149IN22O25Color and Shape:SolidMolecular weight:2197.0109RC-3095
CAS:RC-3095, a selective GRPR antagonist, has been shown to have anti-inflammatory properties in different models of inflammation.Formula:C56H79N15O9Purity:98%Color and Shape:SolidMolecular weight:1106.32BA 1
CAS:Potent BB1, BB2, and BB3 agonist; IC50: 0.26, 1.55, 2.52 nM. Boosts glucose transport in myocytes, promotes cancer cell growth in vitro.Formula:C57H76N14O11Purity:98%Color and Shape:SolidMolecular weight:1133.32PSMA/GRPR ligand 1
PSMA/GRPR ligand 1 (compound 3) is a bispecific ligand with dual targeting capabilities for tumors that express PSMA(+) and GRPR(+).Color and Shape:Odour Solid[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P
CAS:Broad-spectrum inverse agonist; potent at ghrelin receptor (EC50=5.2 nM); blocks other neuropeptide receptors; induces apoptosis; inhibits tumor growth.Formula:C79H109N19O12Purity:98%Color and Shape:SolidMolecular weight:1516.85[D-Phe12]-Bombesin
CAS:Bombesin receptor antagonist
Formula:C74H112N22O18SPurity:98%Color and Shape:SolidMolecular weight:1629.88RC-3095 TFA
CAS:RC-3095 TFA (RC-3095 (TFA)) is a bombesin/gastrin-releasing peptide (BN/GRP) antagonist with potential anticancer activity.Formula:C58H80F3N15O11Purity:98%Color and Shape:SolidMolecular weight:1220.34[D-Phe12,Leu14]-Bombesin
CAS:Bombesin receptor blocker; stops binding in rat brain (IC50=2 μM), hinders amylase release (IC50=4 μM), reduces appetite suppression in vivo.Formula:C77H113F3N22O20Purity:98%Color and Shape:SolidMolecular weight:1724.9GB-6
CAS:GB-6, a short linear peptide that selectively binds to the gastrin releasing peptide receptor (GRPR), shows potential as a high-contrast imaging probe due toFormula:C32H45N11O8Purity:98%Color and Shape:SolidMolecular weight:711.77GRP (14-27) (human, porcine, canine)
CAS:GRP (14-27) (human, porcine, canine) functions as a ligand for bombesin receptors, with its specific binding being inhibited by GTP and GDP, while GMP does notFormula:C75H110N24O16S2Purity:98%Color and Shape:SolidMolecular weight:1667.96Gastrin-Releasing Peptide, human
CAS:Gastrin-releasing peptide, released by vagal fibers, stimulates stomach G cells to secrete gastrin, affecting acid secretion and gut motility.Formula:C130H204N38O31S2Purity:98%Color and Shape:SolidMolecular weight:2859.38(D-Phe6,Leu-NHEt13,des-Met14)-Bombesin (6-14)
CAS:(D-Phe6,Leu-NHEt13,des-Met14)-Bombesin (6-14), a bombesin (BBN) antagonist, holds potential for cancer research applications [1].Formula:C49H69N13O9Color and Shape:SolidMolecular weight:984.15BA 1 TFA
BA1 TFA agonizes BB receptors; binds BRS3, GRPR, NMBR with IC50s of 6, 0.4, 2.5 nM.Formula:C59H77F3N14O13Color and Shape:SolidMolecular weight:1247.32Biotin-Gastrin Releasing Peptide, human TFA
Biotin-Gastrin Releasing Peptide, human TFA, is a biotinylated form of the gastrin-releasing peptide (GRP). GRP is a neuropeptide known for its growth-stimulating and tumorigenic properties.Color and Shape:Odour SolidNOTA-P2-RM26
CAS:NOTA-P2-RM26 is a high-affinity NOTA-conjugated bombesin antagonist designed for GRPR-targeted tumor imaging.Formula:C73H110N18O19Molecular weight:1543.76PD176252
CAS:PD176252 is a BB1 and BB2 antagonist, GRPR inhibitor, and FPR1/FPR2 agonist that inhibits the growth and proliferation of a wide range of cancer cells.Formula:C32H36N6O5Purity:99.00%Color and Shape:SolidMolecular weight:584.67Bombesin
CAS:Bombesin: 14-amino acid peptide from toad skin with two mammalian homologs, neuromedin B and gastrin-releasing peptide.Formula:C71H110N24O18SColor and Shape:While Lyophilized PowderMolecular weight:1619.85ML-18
CAS:ML-18 is a non-peptide bombesin receptor subtype-3 (BRS-3) antagonist with an IC50 of 4.8 μM.Formula:C32H35N5O5Purity:98.62% - >99.99%Color and Shape:SolidMolecular weight:569.65Ref: TM-T4540
1mg34.00€5mg60.00€1mL*10mM (DMSO)75.00€10mg96.00€25mg170.00€50mg264.00€100mg425.00€200mg587.00€Litorin acetate(55749-97-8 Free base)
Litorin acetate, an amphibian bombesin peptide derivative, is an bombesin receptor agonist.Formula:C53H72N14O13SPurity:98.61%Color and Shape:SolidMolecular weight:1145.29Kuwanon H
CAS:Kuwanon H is a potent non-peptide GRP receptor antagonist with a Ki of 290 nM, useful in GRP-related studies.Formula:C45H44O11Purity:97.09% - 97.99%Color and Shape:SolidMolecular weight:760.82Bombesin acetate(31362-50-2 free base)
CAS:Bombesin acetate is a 14-amino acid peptide originally isolated from the skin of the European fire-bellied toad (Bombina bombina).Formula:C73H114N24O20SPurity:98.44%Color and Shape:SolidMolecular weight:1679.92BA 1 acetate(183241-31-8 free base)
BA 1 acetate: bombesin agonist, IC50s: 0.26/1.55/2.52 nM (BB1/BB2/BB3), boosts glucose transport, promotes lung cancer cell growth in vitro.Formula:C59H80N14O13Purity:95.3%Color and Shape:SolidMolecular weight:1193.35[D-Phe12,Leu14]-Bombesin acetate
[D-Phe12,Leu14]-Bombesin acetate inhibits bombesin-stimulated secretion.Formula:C77H118N22O20Purity:98.41% - 99.14%Color and Shape:SolidMolecular weight:1671.9[D-Phe12]-Bombesin acetate
[D-Phe12]-Bombesin acetate inhibits bombesin-stimulated secretion.Formula:C76H116N22O20SPurity:99.81%Color and Shape:SolidMolecular weight:1689.94kuwanon G
CAS:Kuwanon G (Moracenin B) may be used to treat the type II diabetes mellitus as a dual inhibitor of PTP1B and α-glucosidase and as an insulin sensitiser.Formula:C40H36O11Purity:98% - 99.57%Color and Shape:SolidMolecular weight:692.71Ref: TM-T3S1612
1mg63.00€5mg138.00€1mL*10mM (DMSO)178.00€10mg198.00€25mg321.00€50mg465.00€100mg627.00€200mg845.00€Litorin
CAS:Litorin suppresses appetite and stimulates smooth muscle, gastrin, gastric acid, and pancreatic secretion.Formula:C51H68N14O11SColor and Shape:White PowderMolecular weight:1085.24MK-5046
CAS:MK-5046 is a novel BRS-3 agonist, binding to BRS-3 with high affinity (mouse Ki = 1.6 nM, human Ki = 25 nM).Formula:C20H18F6N4OPurity:98.56%Color and Shape:SolidMolecular weight:444.37DSO-5a
CAS:DSO-5a, a potent and selective orally active BB3 agonist, is a DMAKO-00 derivative that enhances ppar-γ activity via BB3 and stimulates ERK1/2 phosphorylation.Formula:C23H24N2O7Purity:98%Color and Shape:SolidMolecular weight:440.45Bag-1
CAS:Bag-1 is a novel potent, non-peptidic bombesin receptor subtype-3 (BRS-3) agonist.Formula:C22H27N3Color and Shape:SolidMolecular weight:333.47PD 168368
CAS:PD 168368 is a mixed neuromodulin B receptor (NMB-R) antagonist and potent FPR1/FPR2/FPR3 agonist that inhibits the gastrin-releasing peptide receptor.Formula:C31H34N6O4Purity:98.11% - 99.87%Color and Shape:SolidMolecular weight:554.64Ref: TM-T8691
1mg84.00€5mg167.00€1mL*10mM (DMSO)197.00€10mg245.00€25mg492.00€50mg737.00€100mg1,054.00€PD 165929
CAS:PD 165929 is a selective antagonist of Bombesin BB1.Formula:C37H47N5O2Purity:98%Color and Shape:SolidMolecular weight:593.8GRPR antagonist-1
GRPR antagonist-1 targets GRPR, kills specific cancer cells (e.g., PC3, Pan02, HGC-27), and promotes apoptosis by modulating Bcl-2 and Bax.Formula:C29H33F3N4O4Color and Shape:SolidMolecular weight:558.59GRPR antagonist-2
GRPR antagonist-2 blocks GRPR, kills some cancer cells, effective on HGC-27 (IC50: 0.77 μM) & Pan02 (IC50: 2.5 μM).Formula:C28H32F3N5O4Color and Shape:SolidMolecular weight:559.58
![[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FTP1931.webp&w=3840&q=75)
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