Opioid Receptor
Opioid receptors are a group of G protein-coupled receptors that mediate the effects of endogenous and exogenous opioids. These receptors play a central role in pain modulation, mood regulation, and addictive behaviors. Opioid receptor agonists and antagonists are extensively used in pain management and addiction treatment, as well as in research on neurological and psychiatric disorders. At CymitQuimica, we provide a comprehensive selection of high-quality opioid receptor modulators to support your research in neurobiology, pain management, and addiction therapy.
Found 296 products of "Opioid Receptor"
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Dynorphin B (1-13) (TFA)
<p>Dynorphin B (1-13) TFA acts as an agonist on opioid κ-receptor .</p>Formula:C76H116N21F3O19Color and Shape:SolidMolecular weight:1684.86Dynorphin B (1-9)
CAS:<p>Dynorphin B (1-9), a neuropeptide and the N-terminal cleavage product of dynorphin B, has its formation inhibited by N-ethylmaleimide (NEM), a non-selective</p>Formula:C54H78N16O12Purity:98%Color and Shape:SolidMolecular weight:1143.3Ac-RYYRWK-NH2 TFA
CAS:<p>Ac-RYYRWK-NH2: potent, specific NOP receptor partial agonist with 0.071 nM affinity; no affinity for μ/κ/δ-opioid receptors.</p>Formula:C51H70F3N15O11Color and Shape:SolidMolecular weight:1126.21KOR agonist 4
<p>KOR agonist 4 (compound 39) is an agonist targeting the κ opioid receptor (Kappa Opioid Receptor) and activates G protein signaling. It has an EC50 of 14 nM and an Emax of 83% for binding to GTPγS. This compound demonstrates moderate to high intrinsic clearance in human liver cells and shows selectivity for the κ opioid receptor over the μ (MOR) and δ (DOR) opioid receptors by factors of 60 and 810, respectively. KOR agonist 4 is useful for research into central nervous system (CNS) disorders.</p>Formula:C21H25N3Color and Shape:SolidMolecular weight:319.44β-Endorphin, equine TFA
<p>β-Endorphin, equine TFA, an endogenous opioid peptide, demonstrates high affinity binding to μ/δ opioid receptors and possesses analgesic properties [1] [2] [3</p>Formula:C156H249F3N42O46SColor and Shape:SolidMolecular weight:3537.96Akuammicine
CAS:<p>Akuammicine, as an indole alkaloid from Catharanthus roseus, can be used in cancer cell eradication.</p>Formula:C20H22N2O2Color and Shape:SolidMolecular weight:322.408Nociceptin(1-7)
CAS:<p>Bioactive metabolite of nociceptin, antagonist of nociceptin-induced hyperalgesia</p>Formula:C31H41N7O9Purity:98%Color and Shape:SolidMolecular weight:655.709[(pF)Phe4]Nociceptin(1-13)NH2
CAS:<p>Potent, selective OP4 agonist; pKi=10.68, pEC50=9.80. >8000x selectivity vs other opioid receptors; long-lasting in vivo effects.</p>Formula:C61H99FN22O15Purity:98%Color and Shape:SolidMolecular weight:1399.6ICI 174,864
CAS:<p>Selective δ opioid antagonist. Exhibits partial agonist in vitro activity at δ receptors at high concentrations.</p>Formula:C38H53N5O7Purity:98%Color and Shape:White SolidMolecular weight:691.87Dermorphin Analog
<p>Dermorphin Analog, a heptapeptide from amphibian skin, binds μ-opioid receptors selectively and strongly.</p>Formula:C44H59N11O10Purity:98%Color and Shape:SolidMolecular weight:901.43PL-017
CAS:<p>μ opioid receptor agonist; IC50: 5.5 nM (μ), >10,000 nM (δ). Induces reversible analgesia, catalepsy, hyperthermia in rats.</p>Formula:C29H37N5O5Purity:98%Color and Shape:SolidMolecular weight:535.64[Met5]-Enkephalin, amide
CAS:<p>[Met5]-Enkephalin, amide activates δ and ζ opioid receptors; has multiple forms and varying plasma levels.</p>Formula:C27H36N6O6SPurity:98%Color and Shape:SolidMolecular weight:572.68MT-7716 hydrochloride
CAS:<p>MT-7716 hydrochloride is a selective agonist of non-peptide nociceptin receptor (NOP)</p>Formula:C27H29ClN4O2Purity:98%Color and Shape:SolidMolecular weight:477Opioid receptor agonist 1
<p>Opioid receptor agonist1 (Compound 2638-28) is an orally active opioid receptor agonist that shows strong affinity for MOR, DOR, and KOR, with Ki values of 5, 24, and 212 nM, respectively. It exhibits analgesic activity in both the mouse warm water tail-flick model and the acetic acid writhing model.</p>Formula:C32H45N5OColor and Shape:SolidMolecular weight:515.73PIPE-3297
<p>PIPE-3297 (compound 25) is a selective kappa opioid receptor (KOR) agonist that activates the G protein signaling pathway with an EC50 of 1.1 nM and exhibits low β-arrestin-2 recruitment activity (10%). Additionally, PIPE-3297 promotes myelination and has anti-inflammatory properties.</p>Formula:C23H30N2OMolecular weight:350.23581[Nphe1]Nociceptin(1-13)NH2
CAS:<p>Competitive nociceptin receptor antagonist with pKi=8.4; no agonist activity; blocks nociceptin effects in vitro/in vivo.</p>Formula:C61H100N22O15Purity:98%Color and Shape:SolidMolecular weight:1381.6SNC 80
CAS:<p>SNC 80, a non-peptide δ-opioid agonist (Ki=1.78 nM, IC50=2.73 nM), also targets μ-δ heteromers (EC50=52.8 nM), with analgesic and antidepressant potential.</p>Formula:C28H39N3O2Purity:99.65%Color and Shape:SolidMolecular weight:449.63[DAla2, DArg6] Dynorphin A, (1-13) (porcine)
CAS:<p>'[DAla2, DArg6] Dynorphin A (1-13) porcine is a potent opioid peptide resistant to enzymatic degradation.'</p>Formula:C76H128N24O15Color and Shape:SolidMolecular weight:1617.98CJ-15208
CAS:<p>CJ-15208: κ-opioid antagonist, IC50: 47 nM kappa, 260 nM mu, 2600 nM delta, reverses asimadoline effects in rabbits (ED50 1.3 µM).</p>Formula:C34H35N5O4Color and Shape:SolidMolecular weight:577.67U-54494A hydrochloride
CAS:<p>U-54494A hydrochloride is a benzamide derivative related to kappa opioid receptor agonists. U-54494A hydrochloride has anticonvulsant activity.</p>Formula:C18H25Cl3N2OColor and Shape:SolidMolecular weight:391.76Ac-RYYRWK-NH2
CAS:<p>Selective NOP receptor partial agonist peptide; Ki=0.71 nM; >4000 nM for μ, δ, κ receptors; boosts food intake in vivo.</p>Formula:C49H69N15O9Purity:98%Color and Shape:SolidMolecular weight:1012.17Gluten Exorphin B5
CAS:<p>Gluten exorphin B5 (GE-B5) is a food-derived opioid peptide identified in digests of wheat gluten.</p>Formula:C30H38N6O7Purity:98%Color and Shape:SolidMolecular weight:594.66Herkinorin
CAS:<p>Herkinorin: μ-opioid agonist with 100x μ-affinity, 50x less κ-affinity than Salvinorin A, from Salvia divinorum. Semi-synthetic from Salvinorin B.</p>Formula:C28H30O8Color and Shape:SolidMolecular weight:494.53Dermorphin
CAS:<p>Dermorphin is agonist of μ-opioid receptor (MOR) agonist.</p>Formula:C40H50N8O10Purity:98.82%Color and Shape:SolidMolecular weight:802.87[Nphe1]Nociceptin(1-13)NH2 TFA
<p>[Nphe1]Nociceptin(1-13)NH2 is a selective nociceptin receptor antagonist with potential analgesic properties, pKi=8.4, pA2=6.0.</p>Formula:C63H101F3N22O17Color and Shape:SolidMolecular weight:1495.61Dynorphin B (1-13)
CAS:<p>Dynorphin B (1-13) acts as an agonist on opioid κ-receptor.</p>Formula:C74H115N21O17Purity:98%Color and Shape:SolidMolecular weight:1570.84β-Endorphin (rat)
CAS:<p>β-Endorphin (β-EP) is an endogenous opioid neuropeptide with diverse biological activities.</p>Formula:C157H254N42O44SColor and Shape:SolidMolecular weight:3466.07CTAP
CAS:<p>Potent μ opioid antagonist, IC50 3.5 nM, 1200x selectivity over δ and somatostatin, brain-penetrant, active in vivo.</p>Formula:C51H69N13O11S2Purity:98%Color and Shape:White Solid/PowderMolecular weight:1104.32Orphanin FQ(1-11)
CAS:<p>Nociceptin peptide fragment (1-11) with potent ORL1/KOR-3 receptor agonism (Ki = 55 nM), no opioid receptor affinity, and analgesic in mice.</p>Formula:C49H75N15O14Purity:98%Color and Shape:SolidMolecular weight:1098.2(N-Me-Tyr1,N-Me-Arg7,D-Leu-NHEt8)-Dynorphin A (1-8)
CAS:<p>E-2078, known chemically as (N-Me-Tyr1,N-Me-Arg7,D-Leu-NHEt8)-Dynorphin A (1-8), is a stable analog of Dynorphin A (1–8) and functions as a kappa opioid</p>Formula:C50H81N15O9Color and Shape:SolidMolecular weight:1036.27β-Naltrexamine dihydrochloride
CAS:<p>β-Naltrexamine dihydrochloride is an orally administered, irreversible opioid receptor antagonist. Its derivatives exhibit optimised subtype selectivity and can be used for pain research.</p>Formula:C20H28Cl2N2O3Purity:95.98%Color and Shape:SoildMolecular weight:415.35Biphalin TFA
CAS:<p>Biphalin TFA is an opioid peptide analog that penetrates the blood-brain barrier (BBB) and encompasses two active enkephalin pharmacophores.</p>Formula:C46H56N10O10·xC2HF3O2Purity:98%Color and Shape:SolidMolecular weight:909.00 (free base)CTOP
CAS:<p>Potent μ-receptor antagonist, Ki=0.96nM, ineffective at δ (>10,000nM). Alters behavior in vivo, boosts K+ currents in rat neurons in vitro, μ-independent.</p>Formula:C50H67N11O11S2Purity:98%Color and Shape:SolidMolecular weight:1062.28Cebranopadol hemicitrate
CAS:<p>Cebranopadol hemicitrate is a NOP and opioid receptor agonist that targets human NOP, MOP, KOP, and δ-opioid peptide (DOP) receptors, with Ki/EC50 values of 0.9 nM/13 nM, 0.7 nM/1.2 nM, 2.6 nM/17 nM, and 18 nM/110 nM, respectively. It is used in studies of acute and chronic pain.</p>Color and Shape:Solid[DPro10] Dynorphin A (1-11)acetate,porcine
<p>[DPro10] Dynorphin A (1-11)acetate,porcine is a highly potent κ-opioid receptor agonist with a Ki value of 0.13 nM.</p>Formula:C65H107N21O15Purity:99.05%Color and Shape:SoildMolecular weight:1422.7Nociceptin (1-13), amide
CAS:<p>Nociceptin (1-13), amide is a potent ORL1 (OP4) receptor agonist with a pEC50 of 7.9 for mouse vas deferens and a Ki of 0.75 nM for binding to rat forebrain</p>Formula:C61H100N22O15Purity:98%Color and Shape:SolidMolecular weight:1381.59Ro 64-6198
CAS:<p>Ro 64-6198: Nonpeptide, selective NOP agonist, high brain uptake, EC50=25.6 nM, 100x NOP>opioid affinity.</p>Formula:C26H31N3OPurity:98%Color and Shape:SolidMolecular weight:401.54[Arg14,Lys15]Nociceptin
CAS:<p>Potent NOP agonist (EC50 = 1 nM), >875x selective vs opioid receptors; outperforms nociceptin in vivo, increases pain perception, reduces movement.</p>Formula:C82H137N31O22Purity:98%Color and Shape:SolidMolecular weight:1909.18N-Desmethyl Loperamide
CAS:<p>N-Desmethyl Loperamide is the major metabolite of loperamide. It is also used as the precusor for radiolabelled loperamide.</p>Formula:C28H31ClN2O2Color and Shape:SolidMolecular weight:463.01MT-7716 free base
CAS:<p>MT-7716: selective NOP agonist, potential in preventing alcohol abuse/relapse.</p>Formula:C27H28N4O2Purity:98%Color and Shape:SolidMolecular weight:440.54Neurotransmitter Receptor Compound Library
<p>A unique collection of 1513 neurotransmitter receptor compounds, can be used for HTS and HCS screening；</p>Color and Shape:Odour SolidBAM-22P
CAS:<p>Bovine adrenal medulla docosapeptide (BAM-22P) is a potent opioid agonist, derived from the proenkephalin A gene, which is present in the adrenal medulla.</p>Formula:C130H184N38O31S2Purity:98%Color and Shape:SolidMolecular weight:2839.22TAN67
CAS:<p>TAN67 is the first effective selective non-peptide delta1 opioid receptor.</p>Formula:C23H26Br2N2OColor and Shape:SolidMolecular weight:506.282Boc-ypgflt(O-tbu)
CAS:<p>Boc-ypgflt(O-tbu) is a delta-receptor-selective opioid antagonist.</p>Formula:C44H64N6O11Color and Shape:SolidMolecular weight:853.01UFP-101
CAS:<p>Strong, selective NOP receptor antagonist with pKi=10.24; >3000x selectivity over δ, μ, κ receptors; blocks nociceptin effects.</p>Formula:C82H138N32O21Purity:98%Color and Shape:SolidMolecular weight:1908.19N-terminally acetylated Endomorphin-1
<p>N-terminally acetylated Endomorphin-1 is a modified Endomorphin-1.</p>Formula:C36H40N6O6Purity:98%Color and Shape:SolidMolecular weight:652.74(Rac)-SNC80
CAS:<p>(Rac)-SNC80, a racemic δ-opioid agonist (K i 1.78 nM), shows potential for treating various headache disorders.</p>Formula:C28H39N3O2Color and Shape:SolidMolecular weight:449.63DAMGO (TFA)
CAS:<p>DAMGO is a selective peptide agonist of the µ-opioid receptor .</p>Formula:C28H36F3N5O8Purity:98%Color and Shape:SolidMolecular weight:627.61Deltorphin acetate
<p>Deltorphin acetate is a substance obtained from the skin secretions of a frog, Phyllomedusa bicolor and shows high selectivity and affinity for δ-opioid</p>Formula:C46H66N10O12S2Purity:98.93%Color and Shape:SolidMolecular weight:1015.21N-Phenethylnoroxymorphone
CAS:<p>N-Phenethylnoroxymorphone is an opioid compound that can enhance morphine-induced analgesia in rats. It is used in the research of neurological disorders.</p>Formula:C24H25NO4Color and Shape:SolidMolecular weight:391.46
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