Opioid Receptor
Opioid receptors are a group of G protein-coupled receptors that mediate the effects of endogenous and exogenous opioids. These receptors play a central role in pain modulation, mood regulation, and addictive behaviors. Opioid receptor agonists and antagonists are extensively used in pain management and addiction treatment, as well as in research on neurological and psychiatric disorders. At CymitQuimica, we provide a comprehensive selection of high-quality opioid receptor modulators to support your research in neurobiology, pain management, and addiction therapy.
Found 326 products of "Opioid Receptor"
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α-Neoendorphin (1-8)
CAS:α-Neoendorphin (1-8) is a 8-amino acid peptide derived from the N-terminal of α-Neoendorphin.Formula:C49H70N12O11Purity:98%Color and Shape:SolidMolecular weight:1003.15HINT1-IN-1
HINT1-IN-1 (compound 8) is an inhibitor of histidine triad nucleotide-binding protein 1 (HINT1) with a Ki of 1.14 μM. It influences the cross-regulation between μ-opioid receptors (MOR) and NMDA receptors (NMDAR).Formula:C23H24N8O5Color and Shape:SolidMolecular weight:492.49KOR agonist 4
KOR agonist 4 (compound 39) is an agonist targeting the κ opioid receptor (Kappa Opioid Receptor) and activates G protein signaling. It has an EC50 of 14 nM and an Emax of 83% for binding to GTPγS. This compound demonstrates moderate to high intrinsic clearance in human liver cells and shows selectivity for the κ opioid receptor over the μ (MOR) and δ (DOR) opioid receptors by factors of 60 and 810, respectively. KOR agonist 4 is useful for research into central nervous system (CNS) disorders.Formula:C21H25N3Color and Shape:SolidMolecular weight:319.44β-Endorphin, equine TFA
β-Endorphin, equine TFA, an endogenous opioid peptide, demonstrates high affinity binding to μ/δ opioid receptors and possesses analgesic properties [1] [2] [3Formula:C156H249F3N42O46SColor and Shape:SolidMolecular weight:3537.96Ac-RYYRWK-NH2 TFA
CAS:Ac-RYYRWK-NH2: potent, specific NOP receptor partial agonist with 0.071 nM affinity; no affinity for μ/κ/δ-opioid receptors.Formula:C51H70F3N15O11Color and Shape:SolidMolecular weight:1126.21Nociceptin(1-7)
CAS:Bioactive metabolite of nociceptin, antagonist of nociceptin-induced hyperalgesiaFormula:C31H41N7O9Purity:98%Color and Shape:SolidMolecular weight:655.709[(pF)Phe4]Nociceptin(1-13)NH2
CAS:Potent, selective OP4 agonist; pKi=10.68, pEC50=9.80. >8000x selectivity vs other opioid receptors; long-lasting in vivo effects.Formula:C61H99FN22O15Purity:98%Color and Shape:SolidMolecular weight:1399.6Dermorphin Analog
Dermorphin Analog, a heptapeptide from amphibian skin, binds μ-opioid receptors selectively and strongly.Formula:C44H59N11O10Purity:98%Color and Shape:SolidMolecular weight:901.43Gluten Exorphin B5
CAS:Gluten exorphin B5 (GE-B5) is a food-derived opioid peptide identified in digests of wheat gluten.Formula:C30H38N6O7Purity:98%Color and Shape:SolidMolecular weight:594.66PL-017
CAS:μ opioid receptor agonist; IC50: 5.5 nM (μ), >10,000 nM (δ). Induces reversible analgesia, catalepsy, hyperthermia in rats.Formula:C29H37N5O5Purity:98%Color and Shape:SolidMolecular weight:535.64[Met5]-Enkephalin, amide
CAS:[Met5]-Enkephalin, amide activates δ and ζ opioid receptors; has multiple forms and varying plasma levels.Formula:C27H36N6O6SPurity:98%Color and Shape:SolidMolecular weight:572.68Ro 64-6198
CAS:Ro 64-6198: Nonpeptide, selective NOP agonist, high brain uptake, EC50=25.6 nM, 100x NOP>opioid affinity.Formula:C26H31N3OPurity:98%Color and Shape:SolidMolecular weight:401.54Opioid receptor agonist 1
Opioid receptor agonist1 (Compound 2638-28) is an orally active opioid receptor agonist that shows strong affinity for MOR, DOR, and KOR, with Ki values of 5, 24, and 212 nM, respectively. It exhibits analgesic activity in both the mouse warm water tail-flick model and the acetic acid writhing model.Formula:C32H45N5OColor and Shape:SolidMolecular weight:515.73Morphiceptin
CAS:Morphiceptin is a synthetic tetrapeptide with morphinelike activities, highly specific for morphine receptors, but not for enkephalin receptors.Formula:C28H35N5O5Molecular weight:521.61U-54494A hydrochloride
CAS:U-54494A hydrochloride is a benzamide derivative related to kappa opioid receptor agonists. U-54494A hydrochloride has anticonvulsant activity.Formula:C18H25Cl3N2OColor and Shape:SolidMolecular weight:391.76N-terminally acetylated Endomorphin-1
N-terminally acetylated Endomorphin-1 is a modified Endomorphin-1.Formula:C36H40N6O6Purity:98%Color and Shape:SolidMolecular weight:652.74UFP-101
CAS:Strong, selective NOP receptor antagonist with pKi=10.24; >3000x selectivity over δ, μ, κ receptors; blocks nociceptin effects.
Formula:C82H138N32O21Purity:98%Color and Shape:SolidMolecular weight:1908.19[Nphe1]Nociceptin(1-13)NH2
CAS:Competitive nociceptin receptor antagonist with pKi=8.4; no agonist activity; blocks nociceptin effects in vitro/in vivo.Formula:C61H100N22O15Purity:98%Color and Shape:SolidMolecular weight:1381.6CJ-15208
CAS:CJ-15208: κ-opioid antagonist, IC50: 47 nM kappa, 260 nM mu, 2600 nM delta, reverses asimadoline effects in rabbits (ED50 1.3 µM).
Formula:C34H35N5O4Color and Shape:SolidMolecular weight:577.67ICI 174,864
CAS:Selective δ opioid antagonist. Exhibits partial agonist in vitro activity at δ receptors at high concentrations.Formula:C38H53N5O7Purity:98%Color and Shape:White SolidMolecular weight:691.87(S,S)-J-113397
CAS:(S,S)-J-113397 is an isomer of J-113397 . J-113397 is an Opioid Receptor antagonist [1] .Formula:C24H37N3O2Color and Shape:SolidMolecular weight:399.57Herkinorin
CAS:Herkinorin: μ-opioid agonist with 100x μ-affinity, 50x less κ-affinity than Salvinorin A, from Salvia divinorum. Semi-synthetic from Salvinorin B.Formula:C28H30O8Color and Shape:SolidMolecular weight:494.53Dynorphin B (1-13) (TFA)
Dynorphin B (1-13) TFA acts as an agonist on opioid κ-receptor .Formula:C76H116N21F3O19Color and Shape:SolidMolecular weight:1684.86Naldemedine
CAS:Naldemedine (S 297995), developed by Shionogi, is a drug for opioid side effects like constipation. It's well tolerated with minor GI issues.Formula:C32H34N4O6Color and Shape:SolidMolecular weight:570.64BPR1M97
CAS:BPR1M97 is a mu opioid receptor (MOP) and neuropeptide-orphin FQ (NOP) receptor agonist with blood-brain barrier permeability and potency, with Kis values of 1.Formula:C18H18Cl2N2OPurity:98.78% - 99.95%Color and Shape:SolidMolecular weight:349.25Neuropeptide AF (human)
CAS:Neuropeptide AF (93-110), Human is an endogenous antiopioid peptide.Formula:C90H132N26O25Purity:98%Color and Shape:SolidMolecular weight:1978.17CTAP
CAS:Potent μ opioid antagonist, IC50 3.5 nM, 1200x selectivity over δ and somatostatin, brain-penetrant, active in vivo.Formula:C51H69N13O11S2Purity:98%Color and Shape:White Solid/PowderMolecular weight:1104.32Dermorphin
CAS:Dermorphin is agonist of μ-opioid receptor (MOR) agonist.Formula:C40H50N8O10Purity:98.82%Color and Shape:SolidMolecular weight:802.87SB 205607 dihydrobromide
CAS:non-peptide δ1 opioid receptor agonistFormula:C23H24N2OPurity:98%Color and Shape:SolidMolecular weight:344.45β-Naltrexamine dihydrochloride
CAS:β-Naltrexamine dihydrochloride is an orally administered, irreversible opioid receptor antagonist. Its derivatives exhibit optimised subtype selectivity and can be used for pain research.Formula:C20H28Cl2N2O3Purity:95.98%Color and Shape:SoildMolecular weight:415.35Ac-RYYRIK-NH2
CAS:NOP site high affinity ligand (Ki=1.5 nM); blocks nociceptin effects in rat brain/heart; agonist in vivo, reduces mouse movement.Formula:C44H70N14O9Purity:98%Color and Shape:SolidMolecular weight:939.12CTOP
CAS:Potent μ-receptor antagonist, Ki=0.96nM, ineffective at δ (>10,000nM). Alters behavior in vivo, boosts K+ currents in rat neurons in vitro, μ-independent.Formula:C50H67N11O11S2Purity:98%Color and Shape:SolidMolecular weight:1062.28SNC 80
CAS:SNC 80, a non-peptide δ-opioid agonist (Ki=1.78 nM, IC50=2.73 nM), also targets μ-δ heteromers (EC50=52.8 nM), with analgesic and antidepressant potential.Formula:C28H39N3O2Purity:99.65%Color and Shape:SolidMolecular weight:449.63Orphanin FQ(1-11)
CAS:Nociceptin peptide fragment (1-11) with potent ORL1/KOR-3 receptor agonism (Ki = 55 nM), no opioid receptor affinity, and analgesic in mice.
Formula:C49H75N15O14Purity:98%Color and Shape:SolidMolecular weight:1098.2[DPro10] Dynorphin A (1-11)acetate,porcine
[DPro10] Dynorphin A (1-11)acetate,porcine is a highly potent κ-opioid receptor agonist with a Ki value of 0.13 nM.Formula:C65H107N21O15Purity:99.59%Color and Shape:SoildMolecular weight:1422.7Dafphedyn
CAS:Dafphedyn (DAFPHEDYN), a potent endorphin 1-13 analog, induces diuresis and analgesia in rats via IV.Formula:C76H124F5N25O14Color and Shape:SolidMolecular weight:1706.95Neurotransmitter Receptor Compound Library
A unique collection of 1513 neurotransmitter receptor compounds, can be used for HTS and HCS screening；
Color and Shape:Odour Solid[Arg14,Lys15]Nociceptin
CAS:Potent NOP agonist (EC50 = 1 nM), >875x selective vs opioid receptors; outperforms nociceptin in vivo, increases pain perception, reduces movement.Formula:C82H137N31O22Purity:98%Color and Shape:SolidMolecular weight:1909.18MT-7716 free base
CAS:MT-7716: selective NOP agonist, potential in preventing alcohol abuse/relapse.Formula:C27H28N4O2Purity:98%Color and Shape:SolidMolecular weight:440.54MT-7716 hydrochloride
CAS:MT-7716 hydrochloride is a selective agonist of non-peptide nociceptin receptor (NOP)Formula:C27H29ClN4O2Purity:98%Color and Shape:SolidMolecular weight:477β-Endorphin (rat)
CAS:β-Endorphin (β-EP) is an endogenous opioid neuropeptide with diverse biological activities.Formula:C157H254N42O44SColor and Shape:SolidMolecular weight:3466.07TAN67
CAS:TAN67 is the first effective selective non-peptide delta1 opioid receptor.
Formula:C23H26Br2N2OColor and Shape:SolidMolecular weight:506.282Boc-ypgflt(O-tbu)
CAS:Boc-ypgflt(O-tbu) is a delta-receptor-selective opioid antagonist.Formula:C44H64N6O11Color and Shape:SolidMolecular weight:853.01Axelopran
CAS:Axelopran (TD-1211) treats opioid constipation; it's a potent, selective peripheral opioid blocker.Formula:C26H39N3O4Color and Shape:SolidMolecular weight:457.61N-Acetyl-α-Endorphin
CAS:N-Acetyl-α-Endorphin is a chemical compound consisting of α-Endorphin that has been acetylated at the N-terminal.Formula:C79H122N18O27SPurity:98%Color and Shape:SolidMolecular weight:1787.98(Rac)-SNC80
CAS:(Rac)-SNC80, a racemic δ-opioid agonist (K i 1.78 nM), shows potential for treating various headache disorders.Formula:C28H39N3O2Color and Shape:SolidMolecular weight:449.63DAMGO (TFA)
CAS:DAMGO is a selective peptide agonist of the µ-opioid receptor .Formula:C28H36F3N5O8Purity:98%Color and Shape:SolidMolecular weight:627.61Clocinnamox mesylate
CAS:Clocinnamox mesylate: irreversible μ-opioid blocker; Ki: 0.7 nM (mouse μ), 1.9 nM (δ), 5.7 nM (κ).Formula:C30H33ClN2O7SColor and Shape:SolidMolecular weight:601.11Ac-RYYRWK-NH2
CAS:Selective NOP receptor partial agonist peptide; Ki=0.71 nM; >4000 nM for μ, δ, κ receptors; boosts food intake in vivo.Formula:C49H69N15O9Purity:98%Color and Shape:SolidMolecular weight:1012.17Dynorphin A (1-13) amide
CAS:Dynorphin A (1-13) amide, an endogenous opioid peptide, counteracts the analgesic effects of morphine [1].Formula:C75H127N25O14Molecular weight:1602.97
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