SGLT
Sodium-glucose co-transporters (SGLTs) are membrane proteins that facilitate the reabsorption of glucose in the kidneys by coupling glucose transport with sodium ions. SGLT inhibitors are an important class of drugs used in the treatment of type 2 diabetes, as they help reduce blood glucose levels by preventing glucose reabsorption in the renal tubules. These inhibitors are also being investigated for their potential benefits in cardiovascular and renal protection. At CymitQuimica, we provide a range of high-quality SGLT modulators to support your research in diabetes, renal physiology, and metabolic disorders.
Found 30 products of "SGLT"
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KGA-2727
CAS:<p>KGA-2727: potent, selective SGLT1 inhibitor (human Ki 97.4 nM, rat 43.5 nM), with high selectivity over SGLT2 for diabetes treatment.</p>Formula:C26H40N4O8Purity:98.46%Color and Shape:SolidMolecular weight:536.62Sergliflozin A
CAS:<p>Sergliflozin A is a selective SGLT2 inhibitor that induces diabetes in a dose-dependent manner. It reduces hyperglycemia.</p>Formula:C20H24O7Purity:99.43%Color and Shape:SolidMolecular weight:376.4O-Desethyl Dapagliflozin
CAS:<p>O-Desethyl Dapagliflozin (Empagliflozin-4) is a SGLT2 inhibitor, IC50=33nM.</p>Formula:C19H21ClO6Purity:98.33%Color and Shape:SolidMolecular weight:380.82Phlorizin
CAS:<p>Phlorizin (Phloridzin) is a non-selective SGLT inhibitor found in apple, for hSGLT1( Ki=300 nM) and hSGLT2( Ki=39 nM) .</p>Formula:C21H24O10Purity:99.73% - 99.77%Color and Shape:Solid CrystallineMolecular weight:436.41Sotagliflozin
CAS:<p>Sotagliflozin (LP-802034) is an orally bioavailable inhibitor of the sodium-glucose co-transporter subtype 1 (SGLT1) and 2 (SGLT2), with potential</p>Formula:C21H25ClO5SPurity:99% - 99.86%Color and Shape:SolidMolecular weight:424.94Empagliflozin
CAS:<p>Empagliflozin (BI 10773) is an SGLT-2 inhibitor (IC50=3.1 nM) that is potent and selective, with more than 300-fold selectivity for SGLT-1/4/5/6.</p>Formula:C23H27ClO7Purity:98% - 99.98%Color and Shape:SolidMolecular weight:450.91Mizagliflozin
CAS:<p>Mizagliflozin is an orally active, selective SGLT1 inhibitor with a Ki value of 27 nM for human SGLT1.Cost-effective and quality-assured.</p>Formula:C28H44N4O8Purity:98.66% - 99.67%Color and Shape:SolidMolecular weight:564.67Dapagliflozin
CAS:<p>Dapagliflozin (BMS-512148) is a selective sodium-glucose co-transporter subtype 2 (SGLT2) inhibitor with antihyperglycemic activity.</p>Formula:C21H25ClO6Purity:99.5% - 99.93%Color and Shape:SolidMolecular weight:408.87Enavogliflozin
CAS:<p>Enavogliflozin (DWP-16001) is an orally available small molecule and sodium glucose transporter 2 inhibitor.</p>Formula:C24H27ClO6Purity:97.37%Color and Shape:SolidMolecular weight:446.92Ipragliflozin
CAS:<p>Ipragliflozin (ASP1941) is under investigation in Type 2 Diabetes and Diabetes Mellitus, Type 2.</p>Formula:C21H21FO5SPurity:99.38% - 99.70%Color and Shape:SolidMolecular weight:404.45T-1095
CAS:<p>T-1095 is an inhibitor of renal glucose reabsorption and the expression of Na+-glucose cotransporters (SGLTs) and facilitative glucose transporter 2 (GLUT2).</p>Formula:C26H28O11Purity:99.78%Color and Shape:SolidMolecular weight:516.49Phloretin
CAS:<p>Phloretin (NSC-407292) inhibits eukaryotic urea transporters, has antioxidative properties, and can induce cancer cell apoptosis. Found in apples and apricots.</p>Formula:C15H14O5Purity:98.53% - >99.99%Color and Shape:SolidMolecular weight:274.27Dapagliflozin ((2S)-1,2-propanediol, hydrate)
CAS:<p>Dapagliflozin ((2S)-1,2-propanediol, hydrate) (BMS-512148 (2S)-1,2-propanediol, hydrate) is a selective, orally active inhibitor of the renal sodium-glucose co-</p>Formula:C24H35ClO9Purity:99.88% - 99.94%Color and Shape:SolidMolecular weight:502.98Canagliflozin
CAS:<p>Canagliflozin (JNJ 28431754AAA) is a selective SGLT2 inhibitor. Canagliflozin is used to treat type II diabetes mellitus. Cost-effective and quality-assured.</p>Formula:C24H25FO5SPurity:98.01% - >99.99%Color and Shape:SolidMolecular weight:444.52Tofogliflozin (hydrate)
CAS:<p>Tofogliflozin hydrate (CSG-452 hydrate) is a potent and highly specific inhibitor of SGLT2(Ki of 2.9 nM, 14.9 nM, and 6.4 nM for human, rat, and mouse SGLT2).</p>Formula:C22H28O7Purity:97.03% - 98.78%Color and Shape:SolidMolecular weight:404.45Ertugliflozin
CAS:<p>PF-04971729 (Ertugliflozin (PF-04971729)) is a potent and selective inhibitor of the sodium-dependent glucose cotransporter 2 (SGLT2).</p>Formula:C22H25ClO7Purity:99.89% - 99.96%Color and Shape:SolidMolecular weight:436.88Bexagliflozin
CAS:<p>Bexagliflozin (EGT1442) is a potent, selective sodium glucose co-transporter 2 (SGLT2) inhibitor with IC50 values of 2 nM for human SGLT2.</p>Formula:C24H29ClO7Purity:98.99% - 99.89%Color and Shape:SolidMolecular weight:464.94Trilobatin
CAS:<p>Trilobatin (P-Phlorizin) has anti-oxidant effect, can increase superoxide dismutase (SOD) activity.Trilobatin has anti-inflammatory effect, it potentially</p>Formula:C21H24O10Purity:97.16%Color and Shape:SolidMolecular weight:436.41Canagliflozin hemihydrate
CAS:<p>Canagliflozin hemihydrate (TA 7284) treats type 2 diabetes by blocking SGLT2, leading to glucose excretion in urine.</p>Formula:C48H52F2O11S2Purity:99.42% - 99.96%Color and Shape:SolidMolecular weight:907.05Dapagliflozin-d5
CAS:<p>Dapagliflozin D5 (BMS-512148 D5) is deuterated Dapagliflozin. Dapagliflozin is a competitive SGLT2 inhibitor.</p>Formula:C21H25ClO6Purity:98%Color and Shape:SolidMolecular weight:413.9Licogliflozin
CAS:<p>Licogliflozin (LIK066) is an inhibitor of sodium-glucose cotransporter (SGLT1 and SGLT2).</p>Formula:C23H28O7Purity:98%Color and Shape:SolidMolecular weight:416.46HSK0935
CAS:<p>HSK0935 is a highly selective and orally available SGLT2 inhibitor (IC50: 1.3 nM). It has antihyperglycemic activities.</p>Formula:C22H25ClO7Purity:98%Color and Shape:SolidMolecular weight:436.88Sergliflozin etabonate
CAS:<p>Sergliflozin etabonate (KGT-1251) is an inhibitor of SGLT2 and can be used in studies about type 2 diabetes and obesity.</p>Formula:C23H28O9Purity:97.88%Color and Shape:SolidMolecular weight:448.46Remogliflozin etabonate
CAS:<p>Remogliflozin etabonate is a prodrug SGLT2 inhibitor; Ki for hSGLT2: 1.95μM, rSGLT2: 2.14μM, rSGLT1: 8.57μM, hSGLT1: 43.1μM.</p>Formula:C26H38N2O9Purity:98.98%Color and Shape:SolidMolecular weight:522.59Velagliflozin
CAS:<p>Velagliflozin is an orally available inhibitor of sodium-glucose cotransporter 2.</p>Formula:C23H25NO5Purity:98%Color and Shape:SolidMolecular weight:395.45Ertugliflozin L-pyroglutamic acid
CAS:<p>Ertugliflozin is a potent oral hSGLT2 inhibitor (IC50: 0.877 nM) for type 2 diabetes treatment studies.</p>Formula:C27H32ClNO10Purity:99.88% - 99.94%Color and Shape:SolidMolecular weight:566SGLT1/2-IN-8
CAS:<p>SGLT1/2-IN-8 (compound 8) is a potent and orally active dual inhibitor of SGLT1/2, exhibiting IC50 values of 4 nM and 1 nM, respectively. It shows antihyperglycemic properties, making it suitable for related research.</p>Formula:C22H26O6Color and Shape:SolidMolecular weight:386.438SGLT inhibitor-1
CAS:<p>SGLT inhibitor-1 is a potentsodium glucose co-transporter proteins (SGLTs) dual inhibitor(hSGLT1 and hSGLT2 with IC50s of 43 nM and 9 nM, respectively).</p>Formula:C24H27FO8Purity:98%Color and Shape:SolidMolecular weight:462.46SGL5213
CAS:<p>SGL5213 is a potent oral SGLT1 inhibitor (IC50: 29 nM) with potential for treating type 2 diabetes.</p>Formula:C37H55N3O8Purity:98%Color and Shape:SolidMolecular weight:669.85Canagliflozin-d4
CAS:<p>Canagliflozin D4 is a deuterium-labeled Canagliflozin. Canagliflozin is an SGLT2 inhibitor.</p>Formula:C24H25FO5SPurity:98%Color and Shape:SolidMolecular weight:448.54
