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Glucagon Receptor

Glucagon Receptor

Glucagon receptors are GPCRs that mediate the effects of glucagon, a hormone involved in regulating glucose homeostasis by promoting glycogen breakdown and glucose release from the liver. These receptors are critical in the management of blood sugar levels and are of particular interest in the study of diabetes and metabolic disorders. Glucagon receptor antagonists are being explored as potential treatments for hyperglycemia in type 2 diabetes. At CymitQuimica, we offer a variety of high-quality glucagon receptor modulators to support your research in endocrinology, diabetes, and metabolic regulation.

Found 164 products of "Glucagon Receptor"

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  • Retatrutide sodium salt


    <p>Retatrutide sodium salt is a glucagon receptor and glucagon-like peptide-1 receptor agonist for the study of type 2 diabetes mellitus.</p>
    Purity:99.97%
    Color and Shape:Soild
  • Retatrutide

    CAS:
    <p>Retatrutide (LY3437943) is a triple agonist of GCGR, GIPR and GLP-1R that can be used to study obesity.</p>
    Formula:C221H342N46O68
    Purity:98.31%
    Color and Shape:Solid
    Molecular weight:4732.09
  • Glucagon (1-29), bovine, human, porcine hydrochloride

    CAS:
    <p>Glucagon (1-29), bovine, human, porcine hydrochloride is a peptide hormone, produced by pancreatic α-cells. Glucagon increases HNF4α phosphorylation.</p>
    Formula:C153H225N43O49S·ClH
    Purity:95.65% - 98.03%
    Color and Shape:Solid
    Molecular weight:3519.21
  • Tirzepatide monosodium salt


    <p>Tirzepatide sodium salt (LY3298176 sodium salt) is a GIP and GLP-1 receptor agonist with neuroprotective activity and can be used to treat obesity.</p>
    Formula:C225H347N48O68Na
    Purity:99.69%
    Color and Shape:Soild
    Molecular weight:4835.51
  • Volagidemab

    CAS:
    <p>Anti-CD34 Antibody is a CHO-expressed humanized monoclonal antibody targeting CD34, which can be used for the study of neurological and cardiovascular diseases.</p>
    Purity:97.8% (SDS-PAGE); 98% (SEC-HPLC) - 97.8% (SDS-PAGE); 98% (SEC-HPLC)
    Color and Shape:Liquid
  • PF-06882961

    CAS:
    <p>PF-06882961 is an orally bioavailable glucagon-like peptide-1 receptor (GLP-1R) agonist.</p>
    Formula:C31H30FN5O4
    Purity:98.06% - 99.54%
    Color and Shape:Solid
    Molecular weight:555.6
  • Avexitide acetate

    CAS:
    <p>Avexitide acetate (exendin 9-39) is a potent glucagon-like peptide 1 receptor (GLP-1R) antagonist for the study of post-obesity hypoglycemia.</p>
    Formula:C155H246N40O53S
    Purity:96.64% - 98.65%
    Color and Shape:Solid
    Molecular weight:3549.91
  • Crotedumab

    CAS:
    <p>Crotedumab (REGN1193) is a humanized antibody targeting GCGR, which reduces fasting blood glucose and improves glucose tolerance, used in diabetes research.</p>
    Purity:>95%
    Color and Shape:Liquid
  • GLP-1 receptor agonist 8

    CAS:
    <p>GLP-1 receptor agonist 8, potent for diabetes and obesity research, may also study NAFLD.</p>
    Formula:C34H36ClFN6O4
    Color and Shape:Solid
    Molecular weight:647.14
  • GLP-1(7-37)

    CAS:
    <p>GLP-1 (7-37) is a truncated, bioactive form of GLP-1 that is the product of proglucagon processing in intestinal endocrine L cells.</p>
    Formula:C151H228N40O47
    Purity:98%
    Color and Shape:Solid
    Molecular weight:3355.67
  • Oxyntomodulin

    CAS:
    <p>GLP-1 analog modulates appetite, boosts metabolism, and curbs gastric acid. Increases cAMP, mildly stimulates glucagon receptor.</p>
    Formula:C192H295N59O60S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:4421.86
  • HAEGTFTSD

    CAS:
    <p>HAEGTFTSD is GLP-1's initial segment; GLP-1 (7-36) amide, tied to food intake, stems from preproglucagon in L-cells.</p>
    Formula:C40H57N11O17
    Purity:98%
    Color and Shape:Solid
    Molecular weight:963.94
  • Exendin-3/4 (59-86)


    <p>Exendin-3/4 (59-86) is a Exendin-4 peptide derivative.</p>
    Formula:NA
    Purity:98%
    Color and Shape:Solid
    Molecular weight:3055.49
  • Secretin, porcine

    CAS:
    <p>Porcine secretin: 27-amino acid peptide for diagnosing pancreatic dysfunction and gastrinoma, stimulates bicarbonate fluid.</p>
    Formula:C130H220N44O41·xC2H4O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:N/A
  • [Des-His1,Glu9]-Glucagon amide

    CAS:
    <p>Glucagon blocker with pA2 of 7.2; no agonist effect. Boosts insulin; prevents glucagon-driven hyperglycemia in rabbits and diabetic rats.</p>
    Formula:C148H221N41O47S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:3358.68
  • Albiglutide fragment TFA


    <p>Albiglutide fragment (GLP-1 (7-36) analog) TFA represents a biologically active segment of Albiglutide, resistant to DPP-4 degradation due to its structure as a</p>
    Formula:C148H224N40O45·xC2HF3O2
    Color and Shape:Solid
  • V-0219 hydrochloride


    <p>V-0219 hydrochloride: oral GLP-1R PAM for obesity-linked diabetes study.</p>
    Formula:C20H26ClF3N4O2
    Purity:99.97%
    Color and Shape:Soild
    Molecular weight:446.89
  • GIP/GLP-1 dual receptor agonist-1

    CAS:
    <p>Compound 4: GIP/GLP-1 agonist for metabolic/fatty liver disease research.</p>
    Color and Shape:Solid
  • (R)-V-0219 hydrochloride


    <p>(R)-V-0219 hydrochloride: Oral GLP-1R PAM, enantiomer of V-0219, triggers Ca2+ flux in hGLP-1R HEK cells.</p>
    Formula:C20H26ClF3N4O2
    Color and Shape:Solid
    Molecular weight:446.89
  • (S, R)-LSN 3318839

    CAS:
    <p>(S,R)-LSN 3318839 enhances GLP-1R, shows strong blood sugar lowering in animals, works with sitagliptin.</p>
    Formula:C26H23Cl2N3O2
    Purity:99.57%
    Color and Shape:Soild
    Molecular weight:480.39
  • LSN3160440

    CAS:
    <p>LSN3160440 is a GLP-1R allosteric modulator and PPI stabilizer aiding inactive GLP-1 attachment.</p>
    Formula:C27H27Cl2N3O
    Color and Shape:Solid
    Molecular weight:480.43
  • VU0453379 hydrochloride


    <p>VU0453379 hydrochloride: selective CNS-penetrant GLP-1R PAM, EC50 1.3 μM.</p>
    Formula:C26H35ClN4O2
    Color and Shape:Solid
    Molecular weight:471.03
  • GLP-1R agonist 14

    CAS:
    <p>GLP-1R agonist 14, also known as Compound 14, is a potent agonist of the GLP-1 receptor, demonstrating an EC50 range of 0-20 nM against human GLP-1 [1].</p>
    Formula:C45H42F2N10O5
    Color and Shape:Solid
    Molecular weight:840.88
  • GLP-1R Antagonist 1

    CAS:
    <p>GLP-1R Antagonist 1 is an orally active, CNS penetrant and non-competitive glucagon-like peptide 1 receptor (GLP-1R) antagonist (IC50: 650 nM).</p>
    Formula:C16H11ClF6N4O2
    Purity:99.84%
    Color and Shape:Solid
    Molecular weight:440.73
  • GLP-1 receptor agonist 13


    <p>Compound (S)-9, a GLP-1 receptor agonist, exhibits an EC50 of 76 nM for the glucagon GLP-1 receptor [1].</p>
    Formula:C25H23ClF2N6O
    Color and Shape:Solid
    Molecular weight:496.94
  • Albiglutide Fragment

    CAS:
    <p>Albiglutide fragment is a 30-amino-acid sequence of modified human GLP-1 (fragment 7-36).</p>
    Formula:C148H224N40O45
    Purity:98%
    Color and Shape:Solid
    Molecular weight:3283.6
  • Tirzepatide

    CAS:
    <p>Tirzepatide (LY-3298176) is a dual glucose-dependent polypeptide (GIP) (EC50=0.042 nM) and glucagon-like peptide-1 (GLP-1) (EC50=0.086 nM) receptor agonist.</p>
    Formula:C225H348N48O68
    Purity:99.52% - 99.99%
    Color and Shape:Solid
    Molecular weight:4813.45
  • Cinnamtannin A2

    CAS:
    <p>Cinnamtannin A2, a tetrameric procyanidin, boosts GLP-1, insulin, CRH expression, and has antioxidant, anti-diabetic, nephroprotective properties.</p>
    Formula:C60H50O24
    Color and Shape:Solid
    Molecular weight:1155.02
  • {Val1}-Exendin-3/4


    <p>{Val1}- exendin-3/4 is the first n-terminal 1-28 residue of exendin-4 peptide.</p>
    Formula:NA
    Purity:98%
    Color and Shape:Solid
    Molecular weight:3241.7
  • Tirzepatide hydrochloride


    <p>Tirzepatide HCl is a dual GIP and GLP-1 receptor agonist.</p>
    Formula:C225H349N48O68Cl
    Purity:98%
    Color and Shape:Solid
    Molecular weight:4849.91
  • GLP-1R agonist 29


    <p>GLP-1R agonist 29 (Compound 20) is a GLP-1R agonist that induces hGLP-1R-mediated cAMP stimulation with an EC50 of 0.018 nM. It exhibits favorable pharmacokinetic properties and shows good in vivo exposure, with an AUC0-∞,sc of 77688 ng·h/mL.</p>
    Color and Shape:Odour Solid
  • GLP-1R agonist 27


    <p>GLP-1R agonist 27 (compound 21) is a potent and orally active GLP-1R agonist. It enhances the accumulation of cyclic adenosine monophosphate (cAMP), reduces blood glucose levels, and decreases food intake. GLP-1R agonist 27 shows potential for research in obesity and type 2 diabetes mellitus (T2DM).</p>
    Formula:C32H33N5O4Se
    Color and Shape:Solid
    Molecular weight:630.6
  • GLP-1 receptor agonist 4

    CAS:
    <p>GLP-1 receptor agonist 4 targets GLP-1R, EC50 64.5 nM, potential diabetes treatment research.</p>
    Formula:C51H44Cl2N4O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:879.82
  • VU0453379

    CAS:
    <p>VU0453379 is a highly selective and central nervous system penetrant positive allosteric modulator of glucagon-like peptide-1R (EC50: 1.3 μM).</p>
    Formula:C26H34N4O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:434.57
  • Glucagon (19-29), human

    CAS:
    <p>Glucagon, a 29-amino-acid hormone, is produced by alpha cells in the pancreas' islets of Langerhans.</p>
    Formula:C61H89N15O18S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1352.53
  • GLP-1 (9-36) amide

    CAS:
    <p>GLP-1 (9-36) amide is an antagonist at the human GLP-1 receptor.</p>
    Formula:C140H214N36O43
    Purity:97%
    Color and Shape:Solid
    Molecular weight:3089.41
  • TT-OAD2 free base

    CAS:
    <p>TT-OAD2 free base, a non-peptide GLP-1 receptor agonist, can treat diabetes; has an EC50 of 5 nM.</p>
    Formula:C50H47Cl2N3O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:856.83
  • Glucagon-like peptide 1 (1-37), human

    CAS:
    <p>Human GLP-1 (1-37) is a potent GLP-1 receptor agonist without impact on rat food intake or insulin secretion.</p>
    Formula:C186H275N51O59
    Purity:98%
    Color and Shape:Solid
    Molecular weight:4169.48
  • Secretin (28-54), human

    CAS:
    <p>Secretin (28-54), human, is a 27-amino acid residue peptide with a C-terminal amidation, acting on human secretin receptors.</p>
    Formula:C130H220N44O40
    Purity:98%
    Color and Shape:Powder
    Molecular weight:3039.46
  • Albenatide

    CAS:
    <p>Albenatide is a modified analog of exendin 4 conjugated to recombinant human albumin.</p>
    Formula:C26H47N7O9S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:633.76
  • HAEGTFTSDVS

    CAS:
    <p>HAEGTFTSDVS is the first N-terminal 1-11 residues of GLP-1 peptide.</p>
    Formula:C48H71N13O20
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1150.18
  • Pal-Glu(OSu)-OH

    CAS:
    <p>Pal-Glu(OSu)-OH is a Liraglutide side chain, a GLP-1 agonist for type 2 diabetes study.</p>
    Formula:C25H42N2O7
    Color and Shape:Solid
    Molecular weight:482.618
  • TT-OAD2

    CAS:
    <p>TT-OAD2 is a non-peptide agonist of glucagon-like peptide-1 (GLP-1) receptor (EC50: 5 nM), with the potential for diabetes treatment.</p>
    Formula:C50H49Cl4N3O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:929.75
  • GLP-2(1-33)(human)

    CAS:
    <p>GLP-2(1-33) (human) is an enteroendocrine hormone which stimulates the growth of the intestinal epithelium.</p>
    Formula:C165H254N44O55S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:3766.19
  • HAEGTFT

    CAS:
    <p>HAEGTFT is the first N-terminal 1-7 residues of GLP-1 peptide.</p>
    Formula:C33H47N9O12
    Purity:98%
    Color and Shape:Solid
    Molecular weight:761.78
  • Taspoglutide

    CAS:
    <p>Taspoglutide is a long-acting glucagon-like peptide 1 (GLP-1) receptor agonist(EC50 value of 0.06 nM),and for treatment of type 2 diabetes</p>
    Formula:C152H232N40O45
    Purity:98%
    Color and Shape:Solid
    Molecular weight:3339.763
  • GLP-1 moiety from Dulaglutide


    <p>GLP-1 moiety from Dulaglutide is a 31-amino acid fragment of Dulaglutide which is a glucagon-like peptide 1 receptor (GLP-1) agonist.</p>
    Formula:C149H221N37O49
    Purity:98%
    Color and Shape:Solid
    Molecular weight:3314.62
  • Apraglutide

    CAS:
    <p>Apraglutide (FE 203799 is a synthetic 33-amino acid peptide and long-acting glp-2 analogue.</p>
    Formula:C172H263N43O52
    Purity:98%
    Color and Shape:Solid
    Molecular weight:3765.25
  • Dulaglutide

    CAS:
    <p>Dulaglutide (LY2189265) is a GLP-1 receptor agonist for studying type 2 diabetes mellitus (T2DM).</p>
    Color and Shape:Solid
  • Glucagon receptor antagonists-1

    CAS:
    <p>Glucagon receptor antagonist -1 is a highly effective glucagon receptor antagonist.</p>
    Formula:C29H34FNO2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:447.58