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Glucagon Receptor

Glucagon Receptor

Glucagon receptors are GPCRs that mediate the effects of glucagon, a hormone involved in regulating glucose homeostasis by promoting glycogen breakdown and glucose release from the liver. These receptors are critical in the management of blood sugar levels and are of particular interest in the study of diabetes and metabolic disorders. Glucagon receptor antagonists are being explored as potential treatments for hyperglycemia in type 2 diabetes. At CymitQuimica, we offer a variety of high-quality glucagon receptor modulators to support your research in endocrinology, diabetes, and metabolic regulation.

Found 164 products of "Glucagon Receptor"

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  • [Des-His1,Glu9]-Glucagon amide
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    [Des-His1,Glu9]-Glucagon amide

    CAS:
    <p>Glucagon blocker with pA2 of 7.2; no agonist effect. Boosts insulin; prevents glucagon-driven hyperglycemia in rabbits and diabetic rats.</p>
    Formula:C148H221N41O47S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:3358.68

    Ref: TM-TP2033

  • GLP-1R agonist 27
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    GLP-1R agonist 27

    <p>GLP-1R agonist 27 (compound 21) is a potent and orally active GLP-1R agonist. It enhances the accumulation of cyclic adenosine monophosphate (cAMP), reduces blood glucose levels, and decreases food intake. GLP-1R agonist 27 shows potential for research in obesity and type 2 diabetes mellitus (T2DM).</p>
    Formula:C32H33N5O4Se
    Color and Shape:Solid
    Molecular weight:630.6

    Ref: TM-T204289

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    (S)-V-0219 hydrochloride

    <p>(S)-V-0219 hydrochloride, a GLP-1R PAM, triggers calcium in hGLP-1R HEK cells, lowers glucose in mice, and reduces fasting hunger.</p>
    Formula:C20H26ClF3N4O2
    Color and Shape:Solid
    Molecular weight:446.89

    Ref: TM-T74265

  • GLP-1R agonist 15
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    GLP-1R agonist 15

    CAS:
    <p>GLP-1R agonist 15 (Compound 101) is a GLP-1 receptor agonist [1] .</p>
    Formula:C46H47FN8O7S
    Color and Shape:Solid
    Molecular weight:874.98

    Ref: TM-T74609

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    Gulgafafusp alfa

    CAS:
    <p>Gulgafafusp alfa is a human IgG2κ monoclonal antibody that selectively binds to the glucagon-like peptide 1 receptor (GLP1R) [1].</p>
    Color and Shape:Liquid

    Ref: TM-T80565

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    Anti-GLP-1R Antibody

    <p>Anti-GLP-1R Antibody is an anti-GLP-1R antibody that can be used for immunohistochemistry of paraffin sections.</p>
    Purity:98.3% (SDS-PAGE); 97.2% (SEC-HPLC) - 98.3% (SDS-PAGE); 97.2% (SEC-HPLC)
    Color and Shape:Odour Liquid

    Ref: TM-T9901A-080

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    SPN009

    <p>SPN009 (Sequence 3) is a GLP-1 receptor (GLP-1 Receptor) agonist, with an EC50 of 2.84 nM, and improves type 2 diabetes in DB/DB mouse models.</p>
    Formula:C191H299N45O59
    Molecular weight:4167.17798

    Ref: TM-TP3525

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    Glucagon-like peptide 1 (1-37), human TFA

    <p>Human Glucagon-like peptide 1 (1-37) TFA is a potent GLP-1 receptor agonist derived from proglucagon.</p>
    Formula:C188H276N51F3O61
    Purity:98%
    Color and Shape:Solid
    Molecular weight:4283.5

    Ref: TM-TP1147

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    GLP-1R agonist 20

    <p>GLP-1R agonist 20 (Compound I-132) is an agonist of the glucagon-like peptide-1 receptor (GLP-1 receptor), with an EC50 value of 0.0162 nM.</p>
    Formula:C31H30Cl2F2N4O5
    Molecular weight:646.15613

    Ref: TM-T209770

  • GLP-1R agonist 16
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    GLP-1R agonist 16

    CAS:
    <p>Compound 115a, a GLP-1R agonist, effectively activates the GLP-1 receptor with an EC50 of 0.15 nM [1].</p>
    Formula:C50H58FN10O6P
    Color and Shape:Solid
    Molecular weight:945.03

    Ref: TM-T74610

  • GLP-1R agonist 4
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    GLP-1R agonist 4

    CAS:
    <p>GLP-1R agonist 4, potentially for diabetes research, is a potent GLP-1R stimulator linked to hypoglycemia.</p>
    Formula:C32H30ClF2N3O5
    Color and Shape:Solid
    Molecular weight:610.05

    Ref: TM-T74323

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    SAR441255

    <p>SAR441255 is a potent unimolecular peptide that acts as a GLP-1/GIP/GCG receptor triagonist, demonstrating balanced activation across all three target receptors</p>
    Color and Shape:Odour Solid

    Ref: TM-T81214

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    FTSDVSKQMEEEAVRLFIEWLKNGGPSSGAPPPS

    <p>FTSDVSKQMEEEAVRLFIEWLKNGGPSSGAPPPS is an Exendin-4 peptide derivative.</p>
    Color and Shape:Solid
    Molecular weight:3692.15

    Ref: TM-T75859

  • Dapiglutide
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    Dapiglutide

    CAS:
    <p>Dapiglutide (ZP7570) is a long-acting GLP-1R &amp; GLP-2R dual agonist for SBS research.</p>
    Color and Shape:Solid

    Ref: TM-T39820

  • GRPP (human)
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    GRPP (human)

    CAS:
    <p>GRPP (human), a 30-amino-acid peptide derived from Gcg, modestly elevates plasma insulin levels while reducing plasma glucagon concentrations.</p>
    Formula:C136H215N41O58S
    Color and Shape:Solid
    Molecular weight:3384.47

    Ref: TM-T80149

  • Glucagon (1-29), bovine, human, porcine
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    Glucagon (1-29), bovine, human, porcine

    CAS:
    <p>Corynoxine B (Cory B) is a naturally occurring alkaloid isolated from Uncaria rhynchophylla (Miq. ) and is an autophagy inducer.</p>
    Formula:C153H225N43O49S
    Purity:99.56% - 99.56%
    Color and Shape:Solid
    Molecular weight:3482.75

    Ref: TM-T15389

  • GLP-1 receptor agonist 7
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    GLP-1 receptor agonist 7

    CAS:
    <p>GLP-1 receptor agonist 7, potential for diabetes research, from patent WO2021219019A1.</p>
    Formula:C31H30ClFN4O5
    Color and Shape:Solid
    Molecular weight:593.05

    Ref: TM-T64195

  • GLP-1 receptor agonist 2
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    GLP-1 receptor agonist 2

    CAS:
    <p>GLP-1 receptor agonist 2 is a glucagon-like peptide-1 receptor (GLP-1R) agonist.</p>
    Formula:C30H31ClFN5O4
    Color and Shape:Solid
    Molecular weight:580.05

    Ref: TM-T11407

  • V-0219
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    V-0219

    CAS:
    <p>V-0219 is a positive allosteric modulator of GLP-1 and can be used in studies about obesity-associated diabetes.</p>
    Formula:C20H25F3N4O2
    Purity:99.91%
    Color and Shape:Soild
    Molecular weight:410.43

    Ref: TM-T60047

  • GLP-1R modulator C16
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    GLP-1R modulator C16

    CAS:
    <p>GLP-1R modulator C16 is a variable modulator that significantly increases the binding affinity of GLP-4.</p>
    Formula:C21H26ClFN2O3
    Purity:99.6% - >99.99%
    Color and Shape:Solid
    Molecular weight:408.89

    Ref: TM-T40997