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Dopamine Receptor

Dopamine Receptor

Dopamine receptors are a group of GPCRs that respond to the neurotransmitter dopamine, playing a key role in the regulation of movement, motivation, reward, and several cognitive functions. These receptors are divided into D1-like and D2-like families, each with distinct functions and pharmacological profiles. Dopamine receptor modulators are widely studied for their applications in treating Parkinson's disease, schizophrenia, addiction, and other neuropsychiatric disorders. At CymitQuimica, we offer a wide range of high-quality dopamine receptor modulators to support your research in neuroscience, mental health, and GPCR signaling.

Found 407 products of "Dopamine Receptor"

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  • Spiperone

    CAS:
    <p>Spiperone (Spiropitan) is a spiro butyrophenone analog similar to HALOPERIDOL and other related compounds.</p>
    Formula:C23H26FN3O2
    Purity:99.34% - 99.91%
    Color and Shape:Solid
    Molecular weight:395.47
  • Bromperidol

    CAS:
    <p>Bromperidol (R-11333) is a butyrophenone derivative and it is a potent and long-acting neuroleptic.</p>
    Formula:C21H23BrFNO2
    Purity:99.89%
    Color and Shape:Tan Solid
    Molecular weight:420.32
  • Itopride hydrochloride

    CAS:
    <p>Itopride hydrochloride (Ganaton) is an AChE and D2DR inhibitor.</p>
    Formula:C20H27ClN2O4
    Purity:99.59%
    Color and Shape:White Or Pale Brownish Crystal
    Molecular weight:394.9
  • ONC206

    CAS:
    <p>ONC206, an analogue of the TRAIL inducer ONC201, acts as a selective antagonist of the D2-like dopamine receptors (DRD2/3/4) at nanomolar concentrations and</p>
    Formula:C23H22F2N4O
    Purity:99.38% - 99.81%
    Color and Shape:Solid
    Molecular weight:408.44
  • Quetiapine hemifumarate

    CAS:
    <p>Quetiapine hemifumarate (ICI-204636), an atypical antipsychotic, is used in the treatment of bipolar I mania, schizophrenia, bipolar I/II depression,.</p>
    Formula:C46H54N6O8S2
    Purity:99.32% - >99.99%
    Color and Shape:White Crystalline Solid
    Molecular weight:883.09
  • Pipamperone

    CAS:
    <p>Pipamperone (McN-JR 3345) binds 5-HT2A closely as receptor.</p>
    Formula:C21H30FN3O2
    Purity:99.85%
    Color and Shape:White Powder
    Molecular weight:375.48
  • Oxidopamine hydrobromide

    CAS:
    <p>Oxidopamine hydrobromide (6-OHDA hydrobromide) is a neurotransmitter dopamine antagonist.</p>
    Formula:C8H12BrNO3
    Purity:98.22% - 99.88%
    Color and Shape:Beige To Brown Fine Crystalline Powder
    Molecular weight:250.09
  • UCM-1306

    CAS:
    <p>UCM-1306: an oral dopamine D1 receptor PAM; boosts DA efficacy, may enhance motor and cognitive function in PD.</p>
    Formula:C14H14FNO2S
    Purity:99.98%
    Color and Shape:Soild
    Molecular weight:279.33
  • Haloperidol

    CAS:
    <p>Haloperidol (Serenace) is a highly potent neuroleptic by relieving nervous through the depression of nerve function.</p>
    Formula:C21H23ClFNO2
    Purity:98.69% - 98.97%
    Color and Shape:Crystals Solid
    Molecular weight:375.86
  • Fluphenazine dihydrochloride

    CAS:
    <p>Fluphenazine dihydrochloride (Prolixin) is an inhibitor of phenothiazine-class D1DR and D2DR. Fluphenazine can be used to probe effects and metabolic process.</p>
    Formula:C22H28Cl2F3N3OS
    Purity:99.23%
    Color and Shape:Off-White Solid
    Molecular weight:510.44
  • D5R agonist 1


    <p>D5R Agonist 1 (Compound 5j) is a selective, orally active partial agonist of the D5 receptor that can penetrate the blood-brain barrier (EC50: 269.7 nM). It has been demonstrated to enhance cognitive abilities in a scopolamine-induced amnesia model.</p>
    Color and Shape:Odour Solid
  • DETQ

    CAS:
    <p>DETQ enhances human D1 dopamine receptor signaling, EC50=5.8 nM, less effective in rats/mice, inactive on D5.</p>
    Formula:C22H25Cl2NO3
    Color and Shape:Solid
    Molecular weight:422.34
  • Losulazine

    CAS:
    <p>Losulazine: a new antihypertensive, requires functional sympathetic nervous system; mechanism undefined.</p>
    Formula:C27H22F4N4O3S
    Purity:98.83%
    Color and Shape:Solid
    Molecular weight:558.55
  • Vanicoside E

    CAS:
    <p>Vanicoside E is an antioxidant and antitumor agent. Vanicoside E inhibits L-Tyrosine and L-DOPA with IC 50 s of 45.23 μM and 189.96 μM, respectively [1] [2] .</p>
    Formula:C53H52O22
    Color and Shape:Solid
    Molecular weight:1040.97
  • Neurotransmitter Receptor Compound Library


    <p>A unique collection of 1513 neurotransmitter receptor compounds, can be used for HTS and HCS screening;</p>
    Color and Shape:Odour Solid
  • Fenoldopam

    CAS:
    <p>Fenoldopam is a selective D1-like dopamine receptor partial agonist (EC50 = 57 nM).</p>
    Formula:C16H16ClNO3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:305.76
  • 7-Hydroxy-PIPAT maleate

    CAS:
    <p>7-Hydroxy-PIPAT maleate is a D3R agonist.</p>
    Formula:C16H22INO
    Color and Shape:Solid
    Molecular weight:371.262
  • [18F]-Labeled L-dopa precursor

    CAS:
    <p>[18F]-Labeled L-dopa precursor is a precursor for synthesis of 18F-labeled L-dopa[1].</p>
    Formula:C35H36N2O7
    Color and Shape:Solid
    Molecular weight:596.67
  • Neuromedin N

    CAS:
    <p>Neuromedin N is a neuropeptide derived from the same precursor polypeptide as neurotensin, and with similar but subtly distinct expression and effects.</p>
    Formula:C38H63N7O8
    Purity:98%
    Color and Shape:Solid
    Molecular weight:745.95
  • ABT 724 trihydrochloride

    CAS:
    <p>ABT-724 trihydrochloride: selective D4 agonist; EC50=12.4nM(human),14.3nM(rat),23.2nM(ferret); for erectile dysfunction research.</p>
    Formula:C17H22Cl3N5
    Purity:99.91%
    Color and Shape:Solid
    Molecular weight:402.75
  • Octodrine

    CAS:
    <p>Octodrine (2-Amino-6-methylheptane) is primarily used as a pharmaceutical intermediate for Octamylamine; it also functions as a local anesthetic and vasoconstrictor.</p>
    Formula:C8H19N
    Purity:99.98%
    Color and Shape:Clear Colorless To Light Yellow Liquid
    Molecular weight:129.24
  • Clomipramine D3

    CAS:
    <p>Clomipramine D3 is deuterium-labeled Clomipramine, blocking serotonin, norepinephrine, dopamine transporters (Ki: 0.14, 54, 3 nM).</p>
    Formula:C19H23ClN2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:317.87
  • MLS1082

    CAS:
    <p>MLS1082 is a D1-like dopamine receptor (D1R) orthosteric modulatothat stimulates G-protein signaling upon dopamine activation for neurodegenerative disorders.</p>
    Formula:C24H23N3O2
    Purity:99.53%
    Color and Shape:Solid
    Molecular weight:385.46
  • D3R/MOR antagonist 1


    <p>Compound 114 (D3R/MOR antagonist 1) exhibits dual antagonistic activity at dopamine D3 receptors (D3R) and mu-opioid receptors (MOR), with K i values of 46.5 nM</p>
    Formula:C22H27Cl2N3O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:420.38
  • Dopamine D2 receptor agonist-2

    CAS:
    <p>Dopamine D2 receptor agonist-2 (Dopamine D2 Receptor) is a ligand targeting the dopamine D2 receptor.</p>
    Formula:C25H31Cl2N5OS
    Purity:98.93%
    Color and Shape:Soild
    Molecular weight:520.52
  • ADTN hydrobromide

    CAS:
    <p>ADTN hydrobromide (6,7-ADTN) is a dopamine receptor agonist (EC50s = 3.5 and 0.65 μM in rat striatal and nucleus accumbens homogenates, respectively).</p>
    Formula:C10H14BrNO2
    Color and Shape:Solid
    Molecular weight:260.13
  • Amisulpride hydrochloride

    CAS:
    <p>Amisulpride is an antagonist of 5-HT7 receptor and dopamine D2 and D3 receptors. It modulates beta 2- arresting signaling and increases neurite outgrowth.</p>
    Formula:C17H28ClN3O4S
    Color and Shape:Solid
    Molecular weight:405.94
  • MOR agonist-2


    <p>Compound 46, designated as MOR agonist-2, serves as a D3R antagonist and a MOR agonist with respective K i values of 7.26 nM and 564 nM.</p>
    Formula:C37H47Cl2N5O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:680.71
  • LE 300

    CAS:
    <p>LE 300 represents a structurally novel type of antagonists acting preferentially at the dopamine D(1)/D(5)receptors and the serotonin 5-HT(2A)receptor.</p>
    Formula:C20H22N2
    Purity:97.91% - 98.79%
    Color and Shape:Solid
    Molecular weight:290.4
  • Moperone

    CAS:
    <p>Moperone (R 1658) is an antagonist of both the D2 dopamine receptor (D2 dopamine receptor) and the D3 dopamine receptor (D3 dopamine receptor), with IC50 values for each of 1.0 nM.</p>
    Formula:C22H26FNO2
    Color and Shape:Solid
    Molecular weight:355.45
  • D3R ligand 1


    <p>D3R Ligand 1 (compound 23b) is a potent, selective antagonist of the dopamine D3 receptor (Ki=66 nM), incorporating a THPB template.</p>
    Formula:C27H37NO5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:455.59
  • ADTN

    CAS:
    <p>ADTN is an agonist of the dopamine receptor.</p>
    Formula:C10H13NO2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:179.22
  • Cabergoline

    CAS:
    <p>Cabergoline (FCE-21336), an ergot-derived dopamine D2-like agonist, targets D2/D3/5-HT2B, normalizes prolactin, controls pituitary tumors.</p>
    Formula:C26H37N5O2
    Purity:97.69% - 99.86%
    Color and Shape:White Crystalline Solid
    Molecular weight:451.6
  • A 77636 hydrochloride

    CAS:
    <p>A 77636 hydrochloride is a potent, orally active, selective and long acting dopamine D1 receptor agonist (pKi=7.40; Ki=39.8 nM).</p>
    Formula:C20H28ClNO3
    Purity:99.57%
    Color and Shape:Solid
    Molecular weight:365.89
  • O-2172

    CAS:
    <p>O-2172 is a carbocyclic analogue serving as an inhibitor of dopamine transporter (DAT), exhibiting IC50 values of 47 nM for DAT and 7000 nM for the serotonin transporter (SERT).</p>
    Formula:C14H16Cl2O2
    Color and Shape:Solid
    Molecular weight:287.18
  • (R)-Preclamol hydrochloride

    CAS:
    <p>(R)-Preclamol HCl is a dopamine agonist stimulating both auto and postsynaptic receptors.</p>
    Formula:C14H22ClNO
    Color and Shape:Solid
    Molecular weight:255.78
  • Haloperidol D4

    CAS:
    <p>Haloperidol D4 is deuterium-labeled haloperidol.</p>
    Formula:C21H23ClFNO2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:379.89
  • Preclamol hydrochloride

    CAS:
    <p>Preclamol hydrochloride: selective dopamine agonist with research potential in schizophrenia.</p>
    Formula:C14H22ClNO
    Color and Shape:Solid
    Molecular weight:255.78
  • Secretoneurin, rat

    CAS:
    <p>Secretoneurin, rat, a 33-amino acid polypeptide, is generated by proteolytic processing of secretogranin II (SgII).</p>
    Formula:C159H252N40O58
    Purity:98%
    Color and Shape:Solid
    Molecular weight:3651.95
  • Fluphenazine free base

    CAS:
    <p>Flufenazine: antipsychotic for schizophrenia, blocks dopamine D2 receptors, reduces hallucinations and delusions.</p>
    Formula:C22H26F3N3OS
    Color and Shape:Solid
    Molecular weight:437.52
  • Adrogolide HCl

    CAS:
    <p>Adrogolide Hydrochloride is a selective dopamine receptor D1 agonist.</p>
    Formula:C22H26ClNO4S
    Color and Shape:Solid
    Molecular weight:435.96
  • N-0500 HCl

    CAS:
    <p>N-0500 HCl, a potent DA receptor agonist, displaces [3H]DP_x005f_x0002_5,6-ADTN with an IC50 of 3nM.</p>
    Formula:C15H22ClNO2
    Purity:98.85% - 99.54%
    Color and Shape:Solid
    Molecular weight:283.79
  • (-)-GSK598809 hydrochloride

    CAS:
    <p>(-)-GSK598809 hydrochloride, a DRD3 selective antagonist, may correct reward deficits in substance dependence.</p>
    Formula:C22H24ClF4N5OS
    Purity:98.36%
    Color and Shape:Soild
    Molecular weight:517.97
  • Quinelorane

    CAS:
    <p>Quinelorane is dextrorotary isomer.</p>
    Formula:C14H22N4
    Color and Shape:Solid
    Molecular weight:246.35
  • PF-4363467

    CAS:
    <p>PF-4363467 is a dopamine D3/D2 receptor antagonist that reduces opioid-seeking behavior without the side effects associated with D2 receptors. It has a Ki value of 3.1 nM for D3R and 692 nM for D2R.</p>
    Formula:C22H30N2O3S
    Color and Shape:Solid
    Molecular weight:402.55
  • D3R/MOR antagonist 2


    <p>Compound 121, a D3R/MOR antagonist with K i values of 361 nM and 85.2 nM for D3R and MOR respectively, has the potential for analgesic effects through MOR</p>
    Formula:C25H31ClN2O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:410.98
  • ST-836 hydrochloride

    CAS:
    <p>ST-836 hydrochloride is a dopamine receptor ligand; Antiparkinsonian agent .</p>
    Formula:C23H35ClN4OS
    Purity:98%
    Color and Shape:Solid
    Molecular weight:451.07
  • cis-(Z)-Flupentixol dihydrochloride

    CAS:
    <p>cis-(Z)-Flupentixol dihydrochloride (Emergil) is a dopamine receptor antagonist.</p>
    Formula:C23H27Cl2F3N2OS
    Purity:98.07%
    Color and Shape:Solid
    Molecular weight:507.44
  • Haloperidol (D4')

    CAS:
    <p>Haloperidol D4' is deuterium-labeled haloperidol. Haloperidol is a dopamine D2 receptor antagonist.</p>
    Formula:C21H23ClFNO2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:379.89
  • Eticlopride hydrochloride

    CAS:
    <p>Eticlopride, an antipsychotic, is a Selective dopamine D2/D3 receptor antagonist (Ki: 0.5/0.16 nM).</p>
    Formula:C17H25ClN2O3·HCl
    Purity:98%
    Color and Shape:Solid
    Molecular weight:377.31