Dopamine Receptor
Dopamine receptors are a group of GPCRs that respond to the neurotransmitter dopamine, playing a key role in the regulation of movement, motivation, reward, and several cognitive functions. These receptors are divided into D1-like and D2-like families, each with distinct functions and pharmacological profiles. Dopamine receptor modulators are widely studied for their applications in treating Parkinson's disease, schizophrenia, addiction, and other neuropsychiatric disorders. At CymitQuimica, we offer a wide range of high-quality dopamine receptor modulators to support your research in neuroscience, mental health, and GPCR signaling.
Found 433 products of "Dopamine Receptor"
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Desethoxy Quetiapine hydrochloride
CAS:Desethoxy quetiapine, an active metabolite of the atypical antipsychotic quetiapine, primarily forms through the action of the cytochrome P450 (CYP) isoform CYP3A5. This compound binds to dopamine D2 receptors with an IC50 value of 1,330 nM. In vivo, desethoxy quetiapine at dosages of 20 and 40 mg/kg mitigates dopamine receptor agonist apomorphine-induced climbing behavior and ameliorates swimming deficits in mice, showcasing its potential modulatory effects on dopamine-mediated behaviors.Formula:C19H21N3OSHClColor and Shape:SolidMolecular weight:412.38PD 128907
CAS:PD 128907 - potent, selective dopamine D2/D3 agonist for researching receptor roles in the brain.Formula:C14H19NO3Purity:98%Color and Shape:SolidMolecular weight:249.31PW0464
CAS:PW0464 ((Rac)-Razpipadon) is a non-catechol D1R agonist and potent omplete G protein biased ligand with an EC50 (Gs-cAMP)=5.8 nM for neurological disorders.Formula:C19H17F2N3O4Purity:98.78%Color and Shape:SolidMolecular weight:389.35LBT 999
CAS:LBT 999 is used as a dopamine reuptake inhibitor.Formula:C20H26FNO2Color and Shape:SolidMolecular weight:331.42Brilaroxazine
CAS:<p>Brilaroxazine (RP5063): multimodal dopamine/5-HT modulator, partial agonist at D2/D3/D4, 5-HT1A/2A, and antagonist at 5-HT2B/7.</p>Formula:C22H25Cl2N3O3Purity:99.36%Color and Shape:SolidMolecular weight:450.36LY-368975
CAS:<p>LY-368975 is a potent and selective inhibitor of the norepinephrine (NE) reuptake site. LY-368975 reduces food consumption in rodents.</p>Formula:C17H21NOSColor and Shape:SolidMolecular weight:287.42CP-293019
CAS:CP-293019 is a potent, selective antagonist of dopamine D4 receptor.Formula:C19H22F2N4OPurity:98%Color and Shape:SolidMolecular weight:360.44-Amino-PPHT Hydrobromide
CAS:4-Amino-PPHT Hydrobromide is a precursor for fluorescent labeled Dopamine D2 receptors agonist.Formula:C21H28N2OPurity:98%Color and Shape:SolidMolecular weight:324.46JNJ-37822681 dihydrochloride
CAS:<p>JNJ-37822681 dihydrochloride 是特异性的、有中枢活性的，可快速解离的多巴胺 D2受体拮抗剂，与多巴胺 D2L 受体结合的亲和力适中 (Ki=158 nM)。JNJ-37822681 dihydrochloride 在精神分裂症和躁郁症领域有研究价值。</p>Formula:C17H19Cl2F5N4Purity:99.78%Color and Shape:SolidMolecular weight:445.26CY 208-243
CAS:CY 208-243 is a selective dopamine D1 receptor agonist with anti-Parkinson disease activity.Formula:C19H18N2Purity:98%Color and Shape:SolidMolecular weight:274.36ABT-670
CAS:<p>ABT-670 is a selective agonist of dopamine D4 receptor. For human D4, ferret D4, and rat D4, the EC50 values are 89 nM, 160 nM, and 93 nM , respectively.</p>Formula:C19H23N3O2Purity:98%Color and Shape:SolidMolecular weight:325.4FAUC-312
CAS:FAUC-312 is a potent and selective agonist of the dopamine D4 receptor.Formula:C21H26N4Purity:98%Color and Shape:SolidMolecular weight:334.46LY3154885
CAS:LY3154885 is an orally active dopamine D1 receptor orthosteric modulator (PAM) that reduces the risk of drug-drug interactions (DDI).Formula:C23H23Cl2N3O2Color and Shape:SolidMolecular weight:444.35Pentiapine
CAS:Pentiapine (CGS 10746) is a novel inhibitor of dopamine release.Formula:C15H17N5SPurity:99.35%Color and Shape:SolidMolecular weight:299.39AJ-76 hydrochloride
CAS:AJ-76 hydrochloride ((+)-AJ 76 hydrochloride) serves as a dopamine autoreceptor antagonist, exhibiting pK i values of 6.95 for hD3, 6.67 for hD4, 6.37 for hD2S, 6.21 for hD2L, and 6.07 for rD2 receptors, indicating its binding affinity strength across these receptor types.Formula:C15H24ClNOColor and Shape:SolidMolecular weight:269.81UWA-101 hydrochloride
CAS:<p>UWA-101 hydrochloride is a selective, non-cytotoxic inhibitor of DAT/SERT, demonstrating EC50 values of 3.6 µM for DAT and 2.3 µM for SERT inhibition. It mitigates motor disorders and other side effects associated with dopaminergic agent use (e.g., L-DOPA) without exhibiting psychotropic effects. This compound is utilized in research focused on neurodegenerative conditions like Parkinson's disease [1] [2].</p>Formula:C13H18ClNO2Color and Shape:SolidMolecular weight:255.74SB-414796
CAS:SB-414796 is a selective antagonist of the dopamine D3 receptor.Formula:C29H36N4O4SPurity:98%Color and Shape:SolidMolecular weight:536.69Naxagolide free base
CAS:Naxagolide is a sustained release formulation. It is a dopamine agonist.Formula:C15H21NO2Purity:98%Color and Shape:SolidMolecular weight:247.33Z1078601926
CAS:Z1078601926 is an allosteric inhibitor of the human dopamine transporter (hDAT) and exhibits a synergistic effect when combined with Nomifensine [1].Formula:C14H19FN2OColor and Shape:SolidMolecular weight:250.31(+)-Dihydrexidine hydrochloride
CAS:(+)-Dihydrexidine hydrochloride is an agonist of dopamine D1 receptor(EC50 of 72± 21 nM).Formula:C17H18ClNO2Purity:98%Color and Shape:SolidMolecular weight:303.78
