CymitQuimica logo
Dopamine Receptor

Dopamine Receptor

Dopamine receptors are a group of GPCRs that respond to the neurotransmitter dopamine, playing a key role in the regulation of movement, motivation, reward, and several cognitive functions. These receptors are divided into D1-like and D2-like families, each with distinct functions and pharmacological profiles. Dopamine receptor modulators are widely studied for their applications in treating Parkinson's disease, schizophrenia, addiction, and other neuropsychiatric disorders. At CymitQuimica, we offer a wide range of high-quality dopamine receptor modulators to support your research in neuroscience, mental health, and GPCR signaling.

Found 433 products of "Dopamine Receptor"

Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
products per page.
  • CM699
    Targetmol
    + Info

    CM699

    CAS:
    <p>CM699 is an effective dual inhibitor of the dopamine transporter (DAT) and Sigma receptor (σR), with IC50 values of 311 nM and 14.1 nM, respectively.</p>
    Formula:C24H29N3O2
    Color and Shape:Solid
    Molecular weight:391.51

    Ref: TM-T207261

  • CymitQuimica logo
    Targetmol
    + Info

    Dopamine D3 receptor ligand-1

    Dopamine D 3 receptor ligand is a potent, selective, high-affinity dopamine D3 receptor ligand that is 89 times more selective for D3 (Ki: 8 nM) than D2 (Ki:
    Formula:C27H29N5O
    Color and Shape:Solid
    Molecular weight:439.55

    Ref: TM-T62528

  • CymitQuimica logo
    Targetmol
    + Info

    Dopamine D3 receptor antagonist-2

    Dopamine D3 receptor antagonist-2 is a dopamine D3 receptor selective (Ki=2.16 nM) or multi-targeting dual ligand that shows potential effects in CNS disorders.
    Formula:C23H27Cl2N3O3
    Color and Shape:Solid
    Molecular weight:464.38

    Ref: TM-T62946

  • RG-15
    Targetmol
    + Info

    RG-15

    CAS:
    RG-15 is an orally active dopamine receptor antagonist with high affinity for the human D2 receptor (pKi of 8.23) and human D3 receptor (pKi of 10.49). It inhibits dopamine-stimulated [35S]GTPγS binding with IC50 values of 21.2 nM in rat striatal membranes, 36.7 nM in mouse A9 cells expressing human D2L receptors, and 7.2 nM in CHO cells expressing human D3 receptors. RG-15 enhances dopamine turnover and synthesis in the striatum and olfactory bulb of mice, exhibiting antipsychotic activity.
    Formula:C25H32Cl2F3N5O2S
    Color and Shape:Solid
    Molecular weight:594.52

    Ref: TM-T206486

  • CymitQuimica logo
    Targetmol
    + Info

    D4R antagonist-1

    <p>Potent, selective D4R antagonist; IC50 = 6.87 µM; potential in Parkinson’s disease research.</p>
    Formula:C21H25F2NO2
    Color and Shape:Solid
    Molecular weight:361.43

    Ref: TM-T61347

  • NMDAR antagonist 5
    Targetmol
    + Info

    NMDAR antagonist 5

    CAS:
    NMDAR antagonist 5 (Compound A17) is a multi-target antagonist that acts on NMDAR and monoamine transporters (SERT, DAT, and NET). It demonstrates strong NMDAR antagonistic efficacy (IC50= 0.3 μM) and effective activity on monoamine transporters (SERT IC50= 1.1 μM, DAT IC50= 0.7 μM, NET IC50= 2.7 μM). NMDAR antagonist 5 exhibits high safety with low toxicity (hepatic and renal toxicity IC50> 100 μM; cardiac toxicity IC50= 24.5 μM). It has antidepressant properties and is useful for depression research.
    Formula:C17H21N3
    Color and Shape:Solid
    Molecular weight:267.369

    Ref: TM-T206943

  • Quinagolide Free Base
    Targetmol
    + Info

    Quinagolide Free Base

    CAS:
    Quinagolide Free Base is a non-ergot dopamine D(2)-agonist.
    Formula:C20H33N3O3S
    Color and Shape:Solid
    Molecular weight:395.56

    Ref: TM-T68483

  • CymitQuimica logo
    Targetmol
    + Info

    D4R antagonis-2

    Potent D4R antagonist-2: selective, IC50=6.52 μM, good in vitro PK and brain penetration, potential for Parkinson's research.
    Formula:C21H23ClF2N2O2
    Color and Shape:Solid
    Molecular weight:408.87

    Ref: TM-T62054

  • Lisuride
    Targetmol
    + Info

    Lisuride

    CAS:
    Lisuride: an oral D2 dopamine agonist, ergot derivative, used in Parkinson's, migraine, and high prolactin research.
    Formula:C20H26N4O
    Color and Shape:Solid
    Molecular weight:338.45

    Ref: TM-T61065

  • Cendifensine
    Targetmol
    + Info

    Cendifensine

    CAS:
    <p>Cendifensine functions as a monoamine reuptake inhibitor, targeting the serotonin transporter (SERT), norepinephrine transporter (NET), and dopamine transporter (DAT).</p>
    Formula:C14H17Cl2NO
    Color and Shape:Solid
    Molecular weight:286.197

    Ref: TM-T206480

  • 3-Hydroxybenzylamine
    Targetmol
    + Info

    3-Hydroxybenzylamine

    CAS:
    <p>3-Hydroxybenzylamine is a useful organic compound for research related to life sciences. The catalog number is T124305 and the CAS number is 73604-31-6.</p>
    Formula:C7H9NO
    Color and Shape:Solid
    Molecular weight:123.155

    Ref: TM-T124305

    ne
    Discontinued
    Discontinued product
  • 6-Chloro-5-(2-chloroethyl)indolin-2-one
    Targetmol
    + Info

    6-Chloro-5-(2-chloroethyl)indolin-2-one

    CAS:
    6-Chloro-5-(2-chloroethyl)indolin-2-one is a useful organic compound for research related to life sciences. The catalog number is T64862 and the CAS number is 118289-55-7.
    Formula:C10H9Cl2NO
    Color and Shape:Solid
    Molecular weight:230.09

    Ref: TM-T64862

    ne
    Discontinued
    Discontinued product
  • GR 218,231
    Targetmol
    + Info

    GR 218,231

    CAS:
    GR 218,231 is a selective antagonist of D3 dopamine receptor.
    Formula:C24H33NO3S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:415.59

    Ref: TM-T27431

    25mg
    Discontinued
    50mg
    Discontinued
    100mg
    Discontinued
    Discontinued product