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S1P Receptor

S1P Receptor

Sphingosine-1-phosphate (S1P) receptors are a family of GPCRs that bind to the lipid signaling molecule sphingosine-1-phosphate. These receptors play critical roles in immune cell trafficking, vascular development, and maintaining the integrity of endothelial barriers. S1P receptor modulators are being developed for the treatment of multiple sclerosis, cancer, and cardiovascular diseases due to their ability to influence immune responses and cell migration. At CymitQuimica, we offer a variety of high-quality S1P receptor modulators to support your research in immunology, oncology, and vascular biology.

Found 17 products of "S1P Receptor"

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  • MP-A08
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    MP-A08

    CAS:
    <p>MP-A08 selectively inhibits SPHK1; targets SphK1 &amp; SphK2 with Ki of 6.9 μM &amp; 27 μM, respectively.</p>
    Formula:C27H25N3O4S2
    Purity:97.44%
    Color and Shape:Solid
    Molecular weight:519.64

    Ref: TM-T16128

  • Azido-FTY720
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    Azido-FTY720

    CAS:
    <p>Azido-FTY720 (azido-Fingolimod) is an analogue of FTY720, with an azido group for click chemistry reactions. FTY720 is an orally available S1P1R modulator .</p>
    Formula:C19H32N4O2
    Color and Shape:Solid
    Molecular weight:348.49

    Ref: TM-T37548

  • SphK1&2-IN-1
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    SphK1&2-IN-1

    CAS:
    <p>SphK1&amp;2-IN-1 is a sphingosine kinase inhibitor with anti-inflammatory, antitumor and hemostatic effects.</p>
    Formula:C14H14N2O3S
    Purity:99.59%
    Color and Shape:Solid
    Molecular weight:290.34

    Ref: TM-T9992

  • Biotin Sphingosine
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    Biotin Sphingosine

    CAS:
    <p>Cimbuterol-d9 is deuterium-labeled Cimbuterol, a 12 β(2)-adrenergic agonist.</p>
    Formula:C28H52N4O4S
    Color and Shape:Solid
    Molecular weight:540.8

    Ref: TM-T83883

  • MHP
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    MHP

    CAS:
    <p>MHP (Methyl caprooyl tyrosinate) is an activator of sphingosine kinase (SPHK1), and significantly stimulates CAMP mRNA and protein production in KC.</p>
    Formula:C16H23NO4
    Purity:98.58%
    Color and Shape:Solid
    Molecular weight:293.36

    Ref: TM-T4658

  • Siponimod
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    Siponimod

    CAS:
    <p>Siponimod (BAF312) modulates S1P1/S1P5 with EC50s of 0.39/0.98 nM; &gt;1000x selectivity over S1P2-4.</p>
    Formula:C29H35F3N2O3
    Purity:97.08% - 99.40%
    Color and Shape:Solid
    Molecular weight:516.59

    Ref: TM-T6403

  • Opaganib
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    Opaganib

    CAS:
    <p>Opaganib (ABC294640) is an orally active and specific sphingosine kinase-2 (SphK2) inhibitor (IC50: 60 μM).</p>
    Formula:C23H25ClN2O
    Purity:98.86% - 99.85%
    Color and Shape:Solid
    Molecular weight:380.91

    Ref: TM-T6750

  • 4-Deoxypyridoxine hydrochloride
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    4-Deoxypyridoxine hydrochloride

    CAS:
    <p>4-Deoxypyridoxine HCl halts S1P breakdown by blocking SPL, reducing apoptosis in insulinoma cells like S1P.</p>
    Formula:C8H12ClNO2
    Purity:99.90%
    Color and Shape:White To Off White Crystalline Powder
    Molecular weight:189.64

    Ref: TM-T38294

  • SK1-I hydrochloride
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    SK1-I hydrochloride

    CAS:
    <p>SK1-I hydrochloride is a selective and competitive SphK1 inhibitor and sphingosine analog ,anti-leukemic to inhibit tumor cell growth and promote apoptosis.</p>
    Formula:C17H28ClNO2
    Purity:99.80%
    Color and Shape:Solid
    Molecular weight:313.86

    Ref: TM-T60798

  • N,N-Dimethylsphingosine
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    N,N-Dimethylsphingosine

    CAS:
    <p>N,N-Dimethylsphingosine,is a potent competitive SphK phosphorylation inhibitor.DMS is elevated in models of neuropathic pain by increasing IL-1β and MCP-1.</p>
    Formula:C20H41NO2
    Purity:98%
    Color and Shape:Clear Colorless To Faint Yellow Liquid/White To Off-White Powder
    Molecular weight:327.55

    Ref: TM-T23045

  • Amgen-23
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    Amgen-23

    CAS:
    <p>Amgen-23 is a selective and highly potent sphingosine kinase 1 (SPHK1) inhibitor that inhibits SPHK2 and can be used in anticancer research.</p>
    Formula:C23H25Cl2N3O2S
    Purity:97.31%
    Color and Shape:Solid
    Molecular weight:478.44

    Ref: TM-T63132

  • SK1-IN-1
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    SK1-IN-1

    CAS:
    <p>SK1-IN-1 is a SPHK1 inhibitor (IC50: 58 nM), with potential anticancer activity, and can be used to study cancer and neurodegenerative diseases.</p>
    Formula:C22H30N4O3
    Purity:98.72%
    Color and Shape:Solid
    Molecular weight:398.5

    Ref: TM-T12927

  • Iso-SLR 080811
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    Iso-SLR 080811

    CAS:
    <p>Iso-SLR 080811 is an isomer of SLR 080811, suitable for relevant research in the life sciences. SLR080811 is a selective SphK2 inhibitor (Ki=1.3 μM).</p>
    Formula:C21H32ClN5O
    Purity:98.34%
    Color and Shape:Solid
    Molecular weight:405.97

    Ref: TM-T70614

  • SLM6031434 HCl
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    SLM6031434 HCl

    CAS:
    <p>SLM6031434 HCl (SLM-6031434 HCl) is a SphK2 inhibitor that reduces LPS-induced TNF伪 and IL-1尾 production.</p>
    Formula:C22H31ClF3N5O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:489.96

    Ref: TM-T28806

  • K6PC-5
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    K6PC-5

    CAS:
    <p>K6PC-5 is a ceramide derivative that acts as an activator of sphingosine kinase 1 (SPHK1), inducing a swift and temporary rise in intracellular calcium levels.</p>
    Formula:C19H37NO4
    Purity:99.9%
    Color and Shape:Solid
    Molecular weight:343.5

    Ref: TM-T27710

  • SAR-114137
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    SAR-114137

    CAS:
    <p>SAR-114137 is a histone sphingomyelin kinase inhibitor used in the study of molluscum arteriosum and peripheral neuropathic pain.</p>
    Formula:C25H34N4O7S
    Purity:99.09% - 99.91%
    Color and Shape:Solid
    Molecular weight:534.63

    Ref: TM-T28658

  • AMG-369
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    AMG-369

    CAS:
    <p>AMG-369 (AMG 247) is an S1P1/S1P5 dual agonist that delays the development of experimental autoimmune encephalomyelitis in rats.</p>
    Formula:C26H22FN3O2S
    Purity:98.04% - 98.92%
    Color and Shape:Solid
    Molecular weight:459.54

    Ref: TM-T29971