S1P Receptor
Sphingosine-1-phosphate (S1P) receptors are a family of GPCRs that bind to the lipid signaling molecule sphingosine-1-phosphate. These receptors play critical roles in immune cell trafficking, vascular development, and maintaining the integrity of endothelial barriers. S1P receptor modulators are being developed for the treatment of multiple sclerosis, cancer, and cardiovascular diseases due to their ability to influence immune responses and cell migration. At CymitQuimica, we offer a variety of high-quality S1P receptor modulators to support your research in immunology, oncology, and vascular biology.
Read more
MP-A08
CAS:219832-49-2
MP-A08 selectively inhibits SPHK1; targets SphK1 & SphK2 with Ki of 6.9 μM & 27 …
Formula:
C27H25N3O4S2
Purity:
98.04%
Color and Shape:
Solid
Molecular weight:
519.64
Ref: TM-T16128
| 5mg | 39.00 € | ||
| 10mg | 58.00 € | ||
| 25mg | 101.00 € | ||
| 50mg | 183.00 € | ||
| 100mg | 325.00 € | ||
| 200mg | 455.00 € |
Estimated delivery in United States, on Wednesday 30 Apr 2025
Amiselimod hydrochloride
CAS:942398-84-7
Amiselimod hydrochloride (MT-1303 hydrochloride) is a sphingosine 1-phosphate receptor-1 (S1P1) modulator.
Formula:
C19H31ClF3NO3
Purity:
99.55%
Color and Shape:
Solid
Molecular weight:
413.9
Ref: TM-T10305
| 1mg | 38.00 € | ||
| 5mg | 80.00 € | ||
| 10mg | 120.00 € | ||
| 25mg | 215.00 € | ||
| 50mg | 354.00 € | ||
| 100mg | 512.00 € | ||
| 1mL*10mM (DMSO) | 88.00 € |
Estimated delivery in United States, on Wednesday 30 Apr 2025
PF429242 dihydrochloride
CAS:2248666-66-0
PF429242 dihydrochloride can reversibly inhibit S1P (IC50 of 175 nM).
Formula:
C25H37Cl2N3O2
Purity:
98.67%
Color and Shape:
Solid
Molecular weight:
482.49
Ref: TM-T12437
| 1mg | 43.00 € | ||
| 5mg | 93.00 € | ||
| 10mg | 120.00 € | ||
| 25mg | 235.00 € | ||
| 50mg | 432.00 € | ||
| 100mg | 620.00 € | ||
| 1mL*10mM (DMSO) | 93.00 € |
Estimated delivery in United States, on Wednesday 30 Apr 2025
CYM50308
CAS:1345858-76-5
CYM50308 is a high affinity agonist of sphingosine-1-phosphate receptor 4 (S1P4-R) (EC50: 56 nM).
Formula:
C20H21F2N3O2S
Purity:
99.43% - 99.63%
Color and Shape:
Solid
Molecular weight:
405.46
Ref: TM-T15032
| 1mg | 62.00 € | ||
| 5mg | 140.00 € | ||
| 10mg | 202.00 € | ||
| 25mg | 324.00 € | ||
| 50mg | 455.00 € | ||
| 100mg | 597.00 € | ||
| 200mg | 842.00 € | ||
| 500mg | 1,225.00 € |
Estimated delivery in United States, on Wednesday 30 Apr 2025
Vibozilimod
CAS:1403232-33-6
Vibozilimod (SCD-044) is S1P receptor-1 (S1PR1) agonist .
Formula:
C29H36ClN3O5
Purity:
99.47%
Color and Shape:
Solid
Molecular weight:
542.07
Ref: TM-T38826
| 1mg | 74.00 € | ||
| 5mg | 170.00 € | ||
| 10mg | 226.00 € | ||
| 25mg | 393.00 € | ||
| 50mg | 567.00 € | ||
| 100mg | 775.00 € | ||
| 200mg | 1,026.00 € |
Estimated delivery in United States, on Friday 2 May 2025
W140 HBr
CAS:1246817-25-3
[(3S)-3-amino-4-(3-hexylanilino)-4-oxobutyl]phosphonic acid;hydrobromide is a S1P1 antagonist with Ki of 2.84 μM.
Formula:
C16H28BrN2O4P
Purity:
99.34%
Color and Shape:
Soild
Molecular weight:
423.28
Ref: TM-T60204
| 1mg | 115.00 € | ||
| 2mg | 172.00 € | ||
| 5mg | 255.00 € | ||
| 10mg | 375.00 € | ||
| 25mg | 562.00 € | ||
| 50mg | 787.00 € | ||
| 100mg | 1,074.00 € | ||
| 1mL*10mM (DMSO) | 284.00 € |
Estimated delivery in United States, on Friday 2 May 2025
SphK1&2-IN-1
CAS:1415662-57-5
SphK1&2-IN-1 is a sphingosine kinase inhibitor with anti-inflammatory, antitumor and hemostatic effects.
Formula:
C14H14N2O3S
Purity:
99.27%
Color and Shape:
Liquid
Molecular weight:
290.34
Ref: TM-T9992
| 1mg | 46.00 € | ||
| 5mg | 89.00 € | ||
| 10mg | 138.00 € | ||
| 25mg | 259.00 € | ||
| 50mg | 373.00 € | ||
| 100mg | 495.00 € | ||
| 200mg | 660.00 € |
Estimated delivery in United States, on Friday 2 May 2025
Ozanimod hydrochloride
CAS:1618636-37-5
Ozanimod (RPC-1063) HCl is a selective S1P1/S1P5 modulator with high affinity, used in relapsing MS …
Formula:
C23H25ClN4O3
Purity:
99.81%
Color and Shape:
Liquid
Molecular weight:
440.92
Ref: TM-T62552
| 1mg | 66.00 € | ||
| 5mg | 139.00 € | ||
| 10mg | 202.00 € | ||
| 25mg | 416.00 € | ||
| 50mg | 652.00 € | ||
| 100mg | 938.00 € | ||
| 500mg | 1,872.00 € | ||
| 1mL*10mM (DMSO) | 154.00 € |
Estimated delivery in United States, on Monday 5 May 2025
SEW2871
CAS:256414-75-2
SEW 2871 is an orally available, highly selective S1P1 agonist. It activates ERK, Akt and …
Formula:
C20H10F6N2OS
Purity:
99.62%
Color and Shape:
White Solid
Molecular weight:
440.36
Ref: TM-T2171
| 1mg | 52.00 € | ||
| 2mg | 84.00 € | ||
| 5mg | 150.00 € | ||
| 10mg | 250.00 € | ||
| 25mg | 414.00 € | ||
| 50mg | 610.00 € | ||
| 1mL*10mM (DMSO) | 145.00 € |
Estimated delivery in United States, on Wednesday 7 May 2025
CYM-5541
CAS:945128-26-7
CYM-5541 (ML249) is a selective and allosteric S1P3 receptor agonist.
Formula:
C19H28N2O2
Purity:
97.34% - 98.39%
Color and Shape:
Solid
Molecular weight:
316.44
Ref: TM-T3961
| 2mg | 38.00 € | ||
| 5mg | 57.00 € | ||
| 10mg | 92.00 € | ||
| 25mg | 160.00 € | ||
| 50mg | 254.00 € | ||
| 100mg | 373.00 € | ||
| 500mg | 873.00 € | ||
| 1mL*10mM (DMSO) | 64.00 € |
Estimated delivery in United States, on Wednesday 7 May 2025
Ponesimod
CAS:854107-55-4
Ponesimod (ACT-128800) is an orally available sphingosine-1-phosphate receptor 1 (S1PR1, S1P1) agonist with potential immunomodulating …
Formula:
C23H25ClN2O4S
Purity:
98.22% - 99.42%
Color and Shape:
Solid
Molecular weight:
460.97
Ref: TM-T3258
| 1mg | 46.00 € | ||
| 2mg | 59.00 € | ||
| 5mg | 93.00 € | ||
| 10mg | 131.00 € | ||
| 25mg | 234.00 € | ||
| 50mg | 404.00 € | ||
| 100mg | 597.00 € | ||
| 500mg | 1,283.00 € | ||
| 1mL*10mM (DMSO) | 97.00 € |
Estimated delivery in United States, on Wednesday 7 May 2025
GLPG2938
CAS:2130996-00-6
GLPG2938 (1-(2-Ethoxy-6-(trifluoromethyl)pyridin-4-yl)-3-((5-methyl-6-(1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)pyridazin-3-yl)methyl)urea) is a potent and
Formula:
C20H19F6N7O2
Purity:
98.25%
Color and Shape:
Solid
Molecular weight:
503.4
Ref: TM-T9199
| 1mg | 84.00 € | ||
| 5mg | 160.00 € | ||
| 10mg | 274.00 € | ||
| 25mg | 550.00 € | ||
| 50mg | 792.00 € | ||
| 100mg | 1,093.00 € | ||
| 1mL*10mM (DMSO) | 170.00 € |
Estimated delivery in United States, on Wednesday 7 May 2025
Siponimod
CAS:1230487-00-9
Siponimod (BAF312) modulates S1P1/S1P5 with EC50s of 0.39/0.98 nM; >1000x selectivity over S1P2-4.
Formula:
C29H35F3N2O3
Purity:
97.08% - 99.40%
Color and Shape:
Solid
Molecular weight:
516.59
Ref: TM-T6403
| 2mg | 39.00 € | ||
| 5mg | 57.00 € | ||
| 10mg | 87.00 € | ||
| 25mg | 139.00 € | ||
| 50mg | 224.00 € | ||
| 100mg | 310.00 € | ||
| 1mL*10mM (DMSO) | 65.00 € |
Estimated delivery in United States, on Wednesday 7 May 2025
MHP
CAS:1104874-94-3
MHP (Methyl caprooyl tyrosinate) is an activator of sphingosine kinase (SPHK1), and significantly stimulates CAMP …
Formula:
C16H23NO4
Purity:
98.58%
Color and Shape:
Solid
Molecular weight:
293.36
Ref: TM-T4658
| 1mg | 47.00 € | ||
| 2mg | 64.00 € | ||
| 5mg | 111.00 € | ||
| 10mg | 188.00 € | ||
| 25mg | 376.00 € | ||
| 50mg | 563.00 € | ||
| 100mg | 800.00 € | ||
| 1mL*10mM (DMSO) | 127.00 € |
Estimated delivery in United States, on Wednesday 7 May 2025
ML-031
CAS:852230-33-2
ML-031 activated S1P2 with an EC50 value of 1 μM in an S1P reporter assay.
Formula:
C19H20N2O3
Purity:
99.21%
Color and Shape:
Solid
Molecular weight:
324.37
Ref: TM-T22101
| 1mg | 63.00 € | ||
| 2mg | 92.00 € | ||
| 5mg | 113.00 € | ||
| 10mg | 187.00 € | ||
| 25mg | 361.00 € | ||
| 50mg | 474.00 € | ||
| 100mg | 688.00 € |
Estimated delivery in United States, on Wednesday 7 May 2025
CYM-5520
CAS:1449747-00-5
CYM-5520 is a noncompetitive allosteric agonist of S1P2
Formula:
C21H19N3O2
Purity:
98.72%
Color and Shape:
Solid
Molecular weight:
345.39
Ref: TM-T22703
| 1mg | 48.00 € | ||
| 2mg | 64.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 142.00 € | ||
| 25mg | 250.00 € | ||
| 50mg | 374.00 € | ||
| 100mg | 557.00 € | ||
| 1mL*10mM (DMSO) | 103.00 € |
Estimated delivery in United States, on Wednesday 7 May 2025
CYM5442
CAS:1094042-01-9
CYM5442 is an S1P agonist, targeting to Sphingosine.
Formula:
C23H27N3O4
Purity:
96.65% - 97.57%
Color and Shape:
Solid
Molecular weight:
409.48
Ref: TM-T2026
| 1mg | 47.00 € | ||
| 2mg | 60.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 137.00 € | ||
| 25mg | 250.00 € | ||
| 50mg | 406.00 € | ||
| 100mg | 620.00 € | ||
| 500mg | 1,283.00 € |
Estimated delivery in United States, on Wednesday 7 May 2025
GSK2018682
CAS:1034688-30-6
GSK2018682 is an agonist of sphingosine-1-phosphate receptor (s1p1) and (s1p5) agonist(pEC50s of 7.7 and 7.2,respectively).
Formula:
C22H21ClN4O4
Purity:
99.04%
Color and Shape:
Solid
Molecular weight:
440.88
Ref: TM-T7360
| 2mg | 35.00 € | ||
| 5mg | 51.00 € | ||
| 10mg | 88.00 € | ||
| 25mg | 154.00 € | ||
| 50mg | 274.00 € | ||
| 100mg | 406.00 € | ||
| 1mL*10mM (DMSO) | 57.00 € |
Estimated delivery in United States, on Wednesday 7 May 2025
S1p receptor agonist 1
CAS:1514888-56-2
S1p receptor agonist 1 (S1p-receptor-agonist-1) is an S1P receptor agonist.
Formula:
C23H24FN3O3
Purity:
99.07% - 99.90%
Color and Shape:
Solid
Molecular weight:
409.45
Ref: TM-T4031
| 1mg | 47.00 € | ||
| 5mg | 127.00 € | ||
| 10mg | 197.00 € | ||
| 25mg | 354.00 € | ||
| 50mg | 540.00 € | ||
| 100mg | 743.00 € |
Estimated delivery in United States, on Wednesday 7 May 2025
Ozanimod
CAS:1306760-87-1
Ozanimod (RPC-1063) (RPC1063) is a specific oral S1P Receptor 1 modulator.
Formula:
C23H24N4O3
Purity:
98.68% - 99.58%
Color and Shape:
Solid
Molecular weight:
404.46
Ref: TM-T6923
| 1mg | 48.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 144.00 € | ||
| 25mg | 283.00 € | ||
| 50mg | 454.00 € | ||
| 100mg | 655.00 € | ||
| 200mg | 929.00 € | ||
| 500mg | 1,378.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Wednesday 7 May 2025
