S1P Receptor
Sphingosine-1-phosphate (S1P) receptors are a family of GPCRs that bind to the lipid signaling molecule sphingosine-1-phosphate. These receptors play critical roles in immune cell trafficking, vascular development, and maintaining the integrity of endothelial barriers. S1P receptor modulators are being developed for the treatment of multiple sclerosis, cancer, and cardiovascular diseases due to their ability to influence immune responses and cell migration. At CymitQuimica, we offer a variety of high-quality S1P receptor modulators to support your research in immunology, oncology, and vascular biology.
Found 17 products of "S1P Receptor"
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MP-A08
CAS:MP-A08 selectively inhibits SPHK1; targets SphK1 & SphK2 with Ki of 6.9 μM & 27 μM, respectively.Formula:C27H25N3O4S2Purity:97.44%Color and Shape:SolidMolecular weight:519.64Azido-FTY720
CAS:Azido-FTY720 (azido-Fingolimod) is an analogue of FTY720, with an azido group for click chemistry reactions. FTY720 is an orally available S1P1R modulator .Formula:C19H32N4O2Color and Shape:SolidMolecular weight:348.49SphK1&2-IN-1
CAS:SphK1&2-IN-1 is a sphingosine kinase inhibitor with anti-inflammatory, antitumor and hemostatic effects.
Formula:C14H14N2O3SPurity:99.59%Color and Shape:SolidMolecular weight:290.34Biotin Sphingosine
CAS:Cimbuterol-d9 is deuterium-labeled Cimbuterol, a 12 β(2)-adrenergic agonist.Formula:C28H52N4O4SColor and Shape:SolidMolecular weight:540.8MHP
CAS:MHP (Methyl caprooyl tyrosinate) is an activator of sphingosine kinase (SPHK1), and significantly stimulates CAMP mRNA and protein production in KC.Formula:C16H23NO4Purity:98.58%Color and Shape:SolidMolecular weight:293.36Ref: TM-T4658
1mg34.00€2mg46.00€5mg66.00€10mg101.00€25mg207.00€50mg334.00€100mg537.00€200mg762.00€1mL*10mM (DMSO)73.00€Siponimod
CAS:Siponimod (BAF312) modulates S1P1/S1P5 with EC50s of 0.39/0.98 nM; >1000x selectivity over S1P2-4.Formula:C29H35F3N2O3Purity:99.13% - 99.8%Color and Shape:SolidMolecular weight:516.59Opaganib
CAS:Opaganib (ABC294640) is an orally active and specific sphingosine kinase-2 (SphK2) inhibitor (IC50: 60 μM).Formula:C23H25ClN2OPurity:98.86% - 99.85%Color and Shape:SolidMolecular weight:380.91Ref: TM-T6750
1mg38.00€2mg50.00€5mg80.00€10mg117.00€25mg227.00€50mg394.00€100mg583.00€1mL*10mM (DMSO)82.00€4-Deoxypyridoxine hydrochloride
CAS:4-Deoxypyridoxine HCl halts S1P breakdown by blocking SPL, reducing apoptosis in insulinoma cells like S1P.Formula:C8H12ClNO2Purity:99.90%Color and Shape:White To Off White Crystalline PowderMolecular weight:189.64SK1-IN-1
CAS:SK1-IN-1 is a SPHK1 inhibitor (IC50: 58 nM), with potential anticancer activity, and can be used to study cancer and neurodegenerative diseases.Formula:C22H30N4O3Purity:98.72%Color and Shape:SolidMolecular weight:398.5SK1-I hydrochloride
CAS:SK1-I hydrochloride is a selective and competitive SphK1 inhibitor and sphingosine analog ,anti-leukemic to inhibit tumor cell growth and promote apoptosis.Formula:C17H28ClNO2Purity:99.80%Color and Shape:SolidMolecular weight:313.86N,N-Dimethylsphingosine
CAS:N,N-Dimethylsphingosine,is a potent competitive SphK phosphorylation inhibitor.DMS is elevated in models of neuropathic pain by increasing IL-1β and MCP-1.Formula:C20H41NO2Purity:98%Color and Shape:Clear Colorless To Faint Yellow Liquid/White To Off-White PowderMolecular weight:327.55SLM6031434 HCl
CAS:SLM6031434 HCl (SLM-6031434 HCl) is a SphK2 inhibitor that reduces LPS-induced TNF伪 and IL-1尾 production.Formula:C22H31ClF3N5O2Purity:98%Color and Shape:SolidMolecular weight:489.96Iso-SLR 080811
CAS:Iso-SLR 080811 is an isomer of SLR 080811, suitable for relevant research in the life sciences. SLR080811 is a selective SphK2 inhibitor (Ki=1.3 μM).Formula:C21H32ClN5OPurity:98.34%Color and Shape:SolidMolecular weight:405.97S1P1 Agonist III
CAS:S1P1 Agonist III is an orally active S1P1 receptor agonist (EC₅₀ = 18 nM) with applications in inflammation, immunology, and receptor signaling studies.Formula:C21H16F3N3O3Purity:99.08%Color and Shape:SolidMolecular weight:415.37Amgen-23
CAS:Amgen-23 is a selective and highly potent sphingosine kinase 1 (SPHK1) inhibitor that inhibits SPHK2 and can be used in anticancer research.Formula:C23H25Cl2N3O2SPurity:97.31%Color and Shape:SolidMolecular weight:478.44K6PC-5
CAS:K6PC-5 is a ceramide derivative that acts as an activator of sphingosine kinase 1 (SPHK1), inducing a swift and temporary rise in intracellular calcium levels.Formula:C19H37NO4Purity:99.9%Color and Shape:SolidMolecular weight:343.5AMG-369
CAS:AMG-369 (AMG 247) is an S1P1/S1P5 dual agonist that delays the development of experimental autoimmune encephalomyelitis in rats.Formula:C26H22FN3O2SPurity:98.04% - 98.92%Color and Shape:SolidMolecular weight:459.54
