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  7. S1P Receptor
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S1P Receptor

Sphingosine-1-phosphate (S1P) receptors are a family of GPCRs that bind to the lipid signaling molecule sphingosine-1-phosphate. These receptors play critical roles in immune cell trafficking, vascular development, and maintaining the integrity of endothelial barriers. S1P receptor modulators are being developed for the treatment of multiple sclerosis, cancer, and cardiovascular diseases due to their ability to influence immune responses and cell migration. At CymitQuimica, we offer a variety of high-quality S1P receptor modulators to support your research in immunology, oncology, and vascular biology.

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products per page. 41 products on this category.

BrandProduct dataPurityPrice rangeEstimated delivery
Targetmol logo
Etrasimod
REF: TM-TQ0227CAS: 1206123-37-6 		99.17% - 99.77%52.00 €~923.00 €Mon 05 May 25
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CS 2100
REF: TM-T22697CAS: 913827-99-3 		98.13%42.00 €~414.00 €Mon 05 May 25
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Opaganib
REF: TM-T6750CAS: 915385-81-8 		98.86% - 99.85%40.00 €~615.00 €Mon 05 May 25
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4-Deoxypyridoxine hydrochloride
REF: TM-T38294CAS: 148-51-6 		99.86%34.00 €Mon 05 May 25
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TY-52156
REF: TM-T17183CAS: 934369-14-9 		99.91%40.00 €~683.00 €Mon 05 May 25
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CYM50374
REF: TM-T27106CAS: 1314212-81-1 		98.4% - 98.49%333.00 €~4,655.00 €Mon 16 Jun 25
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VPC 23019
REF: TM-T17237CAS: 449173-19-7 		98%To inquireMon 16 Jun 25
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ASP-4058
REF: TM-T10385CAS: 952565-91-2 		99.5% - 99.51%99.00 €~2,737.00 €Mon 16 Jun 25
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K6PC-5
REF: TM-T27710CAS: 756875-51-1 		98.55%34.00 €~658.00 €Mon 16 Jun 25
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SK1-IN-1
REF: TM-T12927CAS: 1218816-71-7 		98.72%205.00 €~2,651.00 €Mon 16 Jun 25
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SLM6031434 HCl
REF: TM-T28806CAS: 1897379-34-8 		98%To inquireMon 16 Jun 25
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SLP9101555
REF: TM-T63047		99%333.00 €~4,655.00 €Mon 16 Jun 25
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Ex26
REF: TM-T28643CAS: 1233332-37-0 		99.62%111.00 €~1,293.00 €Mon 16 Jun 25
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N,N-Dimethylsphingosine
REF: TM-T23045CAS: 119567-63-4 		98%To inquireMon 16 Jun 25
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Amgen-23
REF: TM-T63132CAS: 1448706-15-7 		97.31%92.00 €~1,644.00 €Mon 16 Jun 25
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LX-2931
REF: TM-T27864CAS: 948840-25-3 		100% - 99.83%245.00 €~1,758.00 €Mon 16 Jun 25
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BMS-960
REF: TM-T26866CAS: 1265321-86-5 		97.74% - 99.28%712.00 €~4,019.00 €Mon 30 Jun 25
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TASP 0277308
REF: TM-T41145CAS: 945725-50-8 		- - -To inquireMon 30 Jun 25
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Cenerimod
REF: TM-T14924CAS: 1262414-04-9 		97.43% - 99.97%To inquireMon 30 Jun 25
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AMG-369
REF: TM-T29971CAS: 1202073-26-4 		98.39%393.00 €Mon 28 Jul 25
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Etrasimod
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Etrasimod

CAS:1206123-37-6
Etrasimod (APD334) is a specific and orally available antagonist of the sphingosine-1-phosphate-1 (S1P1) receptor (IC50: …
Formula:
C26H26F3NO3
Purity:
99.17% - 99.77%
Color and Shape:
Solid
Molecular weight:
457.48

Ref: TM-TQ0227

1mg52.00 €
5mg111.00 €
10mg180.00 €
25mg243.00 €
50mg305.00 €
100mg424.00 €
1mL*10mM (DMSO)113.00 €
Estimated delivery in United States, on Monday 5 May 2025
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CS 2100
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CS 2100

CAS:913827-99-3
CS 2100 (1-[[4-Ethyl-5-[5-(4-phenoxyphenyl)-1,2,4-oxadiazol-3-yl]-2-thienyl]methyl]-3-azetidinecarboxylic acid) is an S1P1 agonist.
Formula:
C25H23N3O4S
Purity:
98.13%
Color and Shape:
Solid
Molecular weight:
461.53

Ref: TM-T22697

2mg42.00 €
5mg64.00 €
10mg92.00 €
25mg177.00 €
50mg281.00 €
100mg414.00 €
Estimated delivery in United States, on Monday 5 May 2025
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Opaganib
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Opaganib

CAS:915385-81-8
Opaganib (ABC294640) is an orally active and specific sphingosine kinase-2 (SphK2) inhibitor (IC50: 60 μM).
Formula:
C23H25ClN2O
Purity:
98.86% - 99.85%
Color and Shape:
Solid
Molecular weight:
380.91

Ref: TM-T6750

1mg40.00 €
2mg52.00 €
5mg85.00 €
10mg124.00 €
25mg240.00 €
50mg415.00 €
100mg615.00 €
1mL*10mM (DMSO)87.00 €
Estimated delivery in United States, on Monday 5 May 2025
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4-Deoxypyridoxine hydrochloride
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4-Deoxypyridoxine hydrochloride

CAS:148-51-6
4-Deoxypyridoxine HCl halts S1P breakdown by blocking SPL, reducing apoptosis in insulinoma cells like S1P.
Formula:
C8H12ClNO2
Purity:
99.86%
Color and Shape:
White To Off White Crystalline Powder
Molecular weight:
189.64

Ref: TM-T38294

100mg34.00 €
Estimated delivery in United States, on Monday 5 May 2025
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TY-52156
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TY-52156

CAS:934369-14-9
TY-52156 is an effective and selective S1P3 receptor antagonist (Ki: 110 nM).
Formula:
C18H19Cl2N3O
Purity:
99.91%
Color and Shape:
Solid
Molecular weight:
364.27

Ref: TM-T17183

2mg40.00 €
5mg60.00 €
10mg87.00 €
25mg166.00 €
50mg298.00 €
100mg510.00 €
200mg683.00 €
1mL*10mM (DMSO)66.00 €
Estimated delivery in United States, on Monday 5 May 2025
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CYM50374
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CYM50374

CAS:1314212-81-1
CYM50374 inhibits Sphingosine-1-phosphate receptor 4 (S1P4 ) with an IC50 of µM.
Formula:
C19H19NO3S
Purity:
98.4% - 98.49%
Color and Shape:
Solid
Molecular weight:
341.42

Ref: TM-T27106

1mg333.00 €
5mg787.00 €
10mg1,074.00 €
25mg1,510.00 €
50mg1,882.00 €
100mg2,375.00 €
500mg4,655.00 €
Estimated delivery in United States, on Monday 16 Jun 2025
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VPC 23019
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VPC 23019

CAS:449173-19-7
VPC 23019 is a competitive antagonist at the S1P1 and S1P3 receptors (pKi= 7.86 and …
Formula:
C17H29N2O5P
Purity:
98%
Color and Shape:
Solid
Molecular weight:
372.4

Ref: TM-T17237

25mg630.00 €
50mg820.00 €
100mg1,225.00 €
Estimated delivery in United States, on Monday 16 Jun 2025
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ASP-4058
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ASP-4058

CAS:952565-91-2
ASP-4058: Safe, oral S1P1/S1P5 agonist; improves autoimmune encephalomyelitis in mice.
Formula:
C19H12F6N4O2
Purity:
99.5% - 99.51%
Color and Shape:
Solid
Molecular weight:
442.31

Ref: TM-T10385

1mg99.00 €
5mg235.00 €
10mg376.00 €
25mg680.00 €
50mg932.00 €
100mg1,311.00 €
Estimated delivery in United States, on Monday 16 Jun 2025
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K6PC-5
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K6PC-5

CAS:756875-51-1
K6PC-5 is a ceramide derivative that acts as an activator of sphingosine kinase 1 (SPHK1), …
Formula:
C19H37NO4
Purity:
98.55%
Color and Shape:
Solid
Molecular weight:
343.5

Ref: TM-T27710

1mg40.00 €
5mg88.00 €
10mg126.00 €
25mg274.00 €
50mg449.00 €
100mg658.00 €
1mL*10mM (DMSO)87.00 €
Estimated delivery in United States, on Monday 16 Jun 2025
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SK1-IN-1
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SK1-IN-1

CAS:1218816-71-7
SK1-IN-1 is a SPHK1 inhibitor (IC50: 58 nM), with potential anticancer activity, and can be …
Formula:
C22H30N4O3
Purity:
98.72%
Color and Shape:
Solid
Molecular weight:
398.5

Ref: TM-T12927

1mg205.00 €
1mL*10mM (DMSO)289.00 €
Estimated delivery in United States, on Monday 16 Jun 2025
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SLM6031434 HCl
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SLM6031434 HCl

CAS:1897379-34-8
SLM6031434 HCl (SLM-6031434 HCl) is a SphK2 inhibitor that reduces LPS-induced TNF伪 and IL-1尾 production.
Formula:
C22H31ClF3N5O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
489.96

Ref: TM-T28806

1mgTo inquire
5mgTo inquire
10mgTo inquire
Estimated delivery in United States, on Monday 16 Jun 2025
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SLP9101555
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SLP9101555

SLP9101555 is a potent and selective sphingosine kinase 2 (SphK2) inhibitor with a Ki of …
Formula:
C16H22BrClN2
Purity:
99%
Color and Shape:
Liquid
Molecular weight:
357.72

Ref: TM-T63047

1mg333.00 €
5mg787.00 €
10mg1,074.00 €
25mg1,510.00 €
50mg1,882.00 €
100mg2,375.00 €
500mg4,655.00 €
1mL*10mM (DMSO)663.00 €
Estimated delivery in United States, on Monday 16 Jun 2025
+ info
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Ex26
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Ex26

CAS:1233332-37-0
Ex26 (S1P1-IN-Ex26) is an S1P1 antagonist used in experimental autoimmune encephalomyelitis, atherosclerosis, and gastric cancer.
Formula:
C28H28ClFN2O3
Purity:
99.62%
Color and Shape:
Solid
Molecular weight:
494.99

Ref: TM-T28643

1mg111.00 €
5mg269.00 €
10mg432.00 €
25mg697.00 €
50mg938.00 €
100mg1,293.00 €
Estimated delivery in United States, on Monday 16 Jun 2025
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N,N-Dimethylsphingosine
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N,N-Dimethylsphingosine

CAS:119567-63-4
sphingosine kinase (SphK) inhibitor
Formula:
C20H41NO2
Purity:
98%
Color and Shape:
Clear Colorless To Faint Yellow Liquid/White To Off-White Powder
Molecular weight:
327.55

Ref: TM-T23045

5mgTo inquire
10mgTo inquire
25mgTo inquire
50mgTo inquire
Estimated delivery in United States, on Monday 16 Jun 2025
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Amgen-23
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Amgen-23

CAS:1448706-15-7
Amgen-23 is a selective and highly potent sphingosine kinase 1 (SPHK1) inhibitor that inhibits SPHK2 …
Formula:
C23H25Cl2N3O2S
Purity:
97.31%
Color and Shape:
Liquid
Molecular weight:
478.44

Ref: TM-T63132

1mg92.00 €
5mg188.00 €
10mg321.00 €
25mg645.00 €
50mg947.00 €
100mg1,644.00 €
Estimated delivery in United States, on Monday 16 Jun 2025
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LX-2931
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LX-2931

CAS:948840-25-3
LX-2931(LX-3305) is a sphingosine-1-phosphate cleavage enzyme (S1P) inhibitor for the treatment of rheumatoid arthritis.
Formula:
C9H15N3O5
Purity:
100% - 99.83%
Color and Shape:
Solid
Molecular weight:
245.23

Ref: TM-T27864

1mg245.00 €
5mg610.00 €
10mg868.00 €
25mg1,301.00 €
50mg1,758.00 €
Estimated delivery in United States, on Monday 16 Jun 2025
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BMS-960
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BMS-960

CAS:1265321-86-5
BMS-960 is an S1P agonist with potential anti-tumour activity for cancer research.
Formula:
C26H23F3N4O5
Purity:
97.74% - 99.28%
Color and Shape:
Solid
Molecular weight:
528.48

Ref: TM-T26866

1mg712.00 €
5mg1,483.00 €
25mg2,688.00 €
50mg4,019.00 €
Estimated delivery in United States, on Monday 30 Jun 2025
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TASP 0277308
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TASP 0277308

CAS:945725-50-8
NH2-UAMC1110 TFA is an aminobutoxy derivative of UAMC1110 used in the synthesis of FAPI-QS. UAMC1110 …
Formula:
C23H28Cl2N6O3S
Color and Shape:
Solid
Molecular weight:
539.48

Ref: TM-T41145

1mgTo inquire
5mgTo inquire
Estimated delivery in United States, on Monday 30 Jun 2025
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Cenerimod
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Cenerimod

CAS:1262414-04-9
Cenerimod (ACT-334441) is an S1P1 agonist used in the study of murine experimental autoimmune encephalomyelitis …
Formula:
C25H31N3O5
Purity:
97.43% - 99.97%
Color and Shape:
Solid
Molecular weight:
453.53

Ref: TM-T14924

2mg42.00 €
5mg62.00 €
10mg94.00 €
25mg153.00 €
50mg216.00 €
1mL*10mM (DMSO)67.00 €
Estimated delivery in United States, on Monday 30 Jun 2025
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AMG-369
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AMG-369

CAS:1202073-26-4
AMG-369 (AMG 247) is an S1P1/S1P5 dual agonist that delays the development of experimental autoimmune …
Formula:
C26H22FN3O2S
Purity:
98.39%
Color and Shape:
Solid
Molecular weight:
459.54

Ref: TM-T29971

1mg393.00 €
Estimated delivery in United States, on Monday 28 Jul 2025
+ info
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