S1P Receptor
Sphingosine-1-phosphate (S1P) receptors are a family of GPCRs that bind to the lipid signaling molecule sphingosine-1-phosphate. These receptors play critical roles in immune cell trafficking, vascular development, and maintaining the integrity of endothelial barriers. S1P receptor modulators are being developed for the treatment of multiple sclerosis, cancer, and cardiovascular diseases due to their ability to influence immune responses and cell migration. At CymitQuimica, we offer a variety of high-quality S1P receptor modulators to support your research in immunology, oncology, and vascular biology.
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S1p receptor agonist 1
CAS:1514888-56-2
S1p receptor agonist 1 (S1p-receptor-agonist-1) is an S1P receptor agonist.
Formula:
C23H24FN3O3
Purity:
99.07% - 99.90%
Color and Shape:
Solid
Molecular weight:
409.45
Ref: TM-T4031
| 1mg | 46.00 € | ||
| 5mg | 127.00 € | ||
| 10mg | 198.00 € | ||
| 25mg | 354.00 € | ||
| 50mg | 540.00 € | ||
| 100mg | 743.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Ozanimod
CAS:1306760-87-1
Ozanimod (RPC-1063) (RPC1063) is a specific oral S1P Receptor 1 modulator.
Formula:
C23H24N4O3
Purity:
98.68% - 99.74%
Color and Shape:
Solid
Molecular weight:
404.46
Ref: TM-T6923
| 1mg | 48.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 142.00 € | ||
| 25mg | 276.00 € | ||
| 50mg | 444.00 € | ||
| 100mg | 641.00 € | ||
| 200mg | 907.00 € | ||
| 500mg | 1,346.00 € | ||
| 1mL*10mM (DMSO) | 95.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Etrasimod
CAS:1206123-37-6
Etrasimod (APD334) is a specific and orally available antagonist of the sphingosine-1-phosphate-1 (S1P1) receptor (IC50: …
Formula:
C26H26F3NO3
Purity:
99.17% - 99.77%
Color and Shape:
Solid
Molecular weight:
457.48
Ref: TM-TQ0227
| 1mg | 52.00 € | ||
| 5mg | 109.00 € | ||
| 10mg | 176.00 € | ||
| 25mg | 237.00 € | ||
| 50mg | 299.00 € | ||
| 100mg | 414.00 € | ||
| 1mL*10mM (DMSO) | 111.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
SEW2871
CAS:256414-75-2
SEW 2871 is an orally available, highly selective S1P1 agonist. It activates ERK, Akt and …
Formula:
C20H10F6N2OS
Purity:
99.62%
Color and Shape:
White Solid
Molecular weight:
440.36
Ref: TM-T2171
| 1mg | 57.00 € | ||
| 2mg | 82.00 € | ||
| 5mg | 152.00 € | ||
| 10mg | 250.00 € | ||
| 25mg | 405.00 € | ||
| 50mg | 597.00 € | ||
| 1mL*10mM (DMSO) | 145.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
4-Deoxypyridoxine hydrochloride
CAS:148-51-6
4-Deoxypyridoxine HCl halts S1P breakdown by blocking SPL, reducing apoptosis in insulinoma cells like S1P.
Formula:
C8H12ClNO2
Purity:
99.86%
Color and Shape:
White To Off White Crystalline Powder
Molecular weight:
189.64
Ref: TM-T38294
| 100mg | 34.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
TY-52156
CAS:934369-14-9
TY-52156 is an effective and selective S1P3 receptor antagonist (Ki: 110 nM).
Formula:
C18H19Cl2N3O
Purity:
99.91%
Color and Shape:
Solid
Molecular weight:
364.27
Ref: TM-T17183
| 2mg | 40.00 € | ||
| 5mg | 59.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 163.00 € | ||
| 50mg | 292.00 € | ||
| 100mg | 499.00 € | ||
| 200mg | 668.00 € | ||
| 1mL*10mM (DMSO) | 67.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
K6PC-5
CAS:756875-51-1
K6PC-5 is a ceramide derivative that acts as an activator of sphingosine kinase 1 (SPHK1), …
Formula:
C19H37NO4
Purity:
98.55%
Color and Shape:
Solid
Molecular weight:
343.5
Ref: TM-T27710
| 1mg | 40.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 125.00 € | ||
| 25mg | 271.00 € | ||
| 50mg | 443.00 € | ||
| 100mg | 650.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
SLM6031434 HCl
CAS:1897379-34-8
SLM6031434 HCl (SLM-6031434 HCl) is a SphK2 inhibitor that reduces LPS-induced TNF伪 and IL-1尾 production.
Formula:
C22H31ClF3N5O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
489.96
Ref: TM-T28806
| 1mg | 126.00 € | ||
| 5mg | 397.00 € | ||
| 10mg | 546.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
SLP9101555
SLP9101555 is a potent and selective sphingosine kinase 2 (SphK2) inhibitor with a Ki of …
Formula:
C16H22BrClN2
Purity:
99%
Color and Shape:
Liquid
Molecular weight:
357.72
Ref: TM-T63047
| 1mg | 326.00 € | ||
| 5mg | 774.00 € | ||
| 10mg | 1,056.00 € | ||
| 25mg | 1,477.00 € | ||
| 50mg | 1,838.00 € | ||
| 100mg | 2,336.00 € | ||
| 500mg | 4,568.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
Ex26
CAS:1233332-37-0
Ex26 (S1P1-IN-Ex26) is an S1P1 antagonist used in experimental autoimmune encephalomyelitis, atherosclerosis, and gastric cancer.
Formula:
C28H28ClFN2O3
Purity:
99.62%
Color and Shape:
Solid
Molecular weight:
494.99
Ref: TM-T28643
| 1mg | 109.00 € | ||
| 5mg | 264.00 € | ||
| 10mg | 424.00 € | ||
| 25mg | 683.00 € | ||
| 50mg | 920.00 € | ||
| 100mg | 1,267.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
VPC 23019
CAS:449173-19-7
VPC 23019 is a competitive antagonist at the S1P1 and S1P3 receptors (pKi= 7.86 and …
Formula:
C17H29N2O5P
Purity:
98%
Color and Shape:
Solid
Molecular weight:
372.4
Ref: TM-T17237
| 25mg | 616.00 € | ||
| 50mg | 804.00 € | ||
| 100mg | 1,202.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
Amgen-23
CAS:1448706-15-7
Amgen-23 is a selective and highly potent sphingosine kinase 1 (SPHK1) inhibitor that inhibits SPHK2 …
Formula:
C23H25Cl2N3O2S
Color and Shape:
Liquid
Molecular weight:
478.44
Ref: TM-T63132
| 1mg | 89.00 € | ||
| 5mg | 181.00 € | ||
| 10mg | 309.00 € | ||
| 25mg | 619.00 € | ||
| 50mg | 908.00 € | ||
| 100mg | 1,578.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
LX-2931
CAS:948840-25-3
LX-2931(LX-3305) is a sphingosine-1-phosphate cleavage enzyme (S1P) inhibitor for the treatment of rheumatoid arthritis.
Formula:
C9H15N3O5
Purity:
100% - 99.83%
Color and Shape:
Solid
Molecular weight:
245.23
Ref: TM-T27864
| 1mg | 241.00 € | ||
| 5mg | 596.00 € | ||
| 10mg | 848.00 € | ||
| 25mg | 1,280.00 € | ||
| 50mg | 1,723.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
ASP-4058
CAS:952565-91-2
ASP-4058: Safe, oral S1P1/S1P5 agonist; improves autoimmune encephalomyelitis in mice.
Formula:
C19H12F6N4O2
Purity:
99.5% - 99.51%
Color and Shape:
Solid
Molecular weight:
442.31
Ref: TM-T10385
| 1mg | 95.00 € | ||
| 5mg | 226.00 € | ||
| 10mg | 362.00 € | ||
| 25mg | 654.00 € | ||
| 50mg | 896.00 € | ||
| 100mg | 1,262.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
SK1-IN-1
CAS:1218816-71-7
SK1-IN-1 is a SPHK1 inhibitor (IC50: 58 nM), with potential anticancer activity, and can be …
Formula:
C22H30N4O3
Purity:
98.72%
Color and Shape:
Solid
Molecular weight:
398.5
Ref: TM-T12927
| 1mg | 197.00 € | ||
| 1mL*10mM (DMSO) | 278.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
Cenerimod
CAS:1262414-04-9
Cenerimod (ACT-334441) is an S1P1 agonist used in the study of murine experimental autoimmune encephalomyelitis …
Formula:
C25H31N3O5
Purity:
97.43%
Color and Shape:
Solid
Molecular weight:
453.53
Ref: TM-T14924
| 2mg | 42.00 € | ||
| 5mg | 61.00 € | ||
| 10mg | 93.00 € | ||
| 1mL*10mM (DMSO) | 68.00 € |
Estimated delivery in United States, on Wednesday 5 Feb 2025
BMS-960
CAS:1265321-86-5
BMS-960 is an S1P agonist with potential anti-tumour activity for cancer research.
Formula:
C26H23F3N4O5
Purity:
97.74% - 99.28%
Color and Shape:
Solid
Molecular weight:
528.48
Ref: TM-T26866
| 1mg | 705.00 € | ||
| 5mg | 1,467.00 € | ||
| 25mg | 2,661.00 € | ||
| 50mg | 3,978.00 € |
Estimated delivery in United States, on Wednesday 5 Feb 2025
TASP 0277308
CAS:945725-50-8
TASP 0277308 is an S1P1 inhibitor with immunomodulatory and anticancer activity that inhibits S1P- and …
Formula:
C23H28Cl2N6O3S
Color and Shape:
Solid
Molecular weight:
539.48
Ref: TM-T41145
| 1mg | 256.00 € | ||
| 5mg | 627.00 € |
Estimated delivery in United States, on Wednesday 5 Feb 2025
SAR-114137
CAS:537706-31-3
SAR-114137 is a histone sphingomyelin kinase inhibitor used in the study of molluscum arteriosum and …
Formula:
C25H34N4O7S
Purity:
100% - 99.57%
Color and Shape:
Solid
Molecular weight:
534.63
Ref: TM-T28658
| 1mg | 444.00 € | ||
| 5mg | 1,023.00 € | ||
| 10mg | 1,386.00 € | ||
| 25mg | 2,117.00 € | ||
| 50mg | 2,779.00 € |
Estimated delivery in United States, on Wednesday 5 Mar 2025
