S1P Receptor
Sphingosine-1-phosphate (S1P) receptors are a family of GPCRs that bind to the lipid signaling molecule sphingosine-1-phosphate. These receptors play critical roles in immune cell trafficking, vascular development, and maintaining the integrity of endothelial barriers. S1P receptor modulators are being developed for the treatment of multiple sclerosis, cancer, and cardiovascular diseases due to their ability to influence immune responses and cell migration. At CymitQuimica, we offer a variety of high-quality S1P receptor modulators to support your research in immunology, oncology, and vascular biology.
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MHP
CAS:1104874-94-3
MHP (Methyl caprooyl tyrosinate) is an activator of sphingosine kinase (SPHK1), and significantly stimulates CAMP …
Formula:
C16H23NO4
Purity:
99.45%
Color and Shape:
Solid
Molecular weight:
293.36
Ref: TM-T4658
| 1mg | 47.00 € | ||
| 2mg | 64.00 € | ||
| 5mg | 111.00 € | ||
| 10mg | 188.00 € | ||
| 25mg | 376.00 € | ||
| 50mg | 563.00 € | ||
| 100mg | 800.00 € | ||
| 1mL*10mM (DMSO) | 127.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
CS 2100
CAS:913827-99-3
CS 2100 (1-[[4-Ethyl-5-[5-(4-phenoxyphenyl)-1,2,4-oxadiazol-3-yl]-2-thienyl]methyl]-3-azetidinecarboxylic acid) is an S1P1 agonist.
Formula:
C25H23N3O4S
Purity:
98.13%
Color and Shape:
Solid
Molecular weight:
461.53
Ref: TM-T22697
| 2mg | 42.00 € | ||
| 5mg | 64.00 € | ||
| 10mg | 92.00 € | ||
| 25mg | 177.00 € | ||
| 50mg | 281.00 € | ||
| 100mg | 414.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
CYM-5520
CAS:1449747-00-5
CYM-5520 is a noncompetitive allosteric agonist of S1P2
Formula:
C21H19N3O2
Purity:
98.72%
Color and Shape:
Solid
Molecular weight:
345.39
Ref: TM-T22703
| 1mg | 48.00 € | ||
| 2mg | 64.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 142.00 € | ||
| 25mg | 250.00 € | ||
| 50mg | 374.00 € | ||
| 100mg | 557.00 € | ||
| 1mL*10mM (DMSO) | 103.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
Opaganib
CAS:915385-81-8
Opaganib (ABC294640) is an orally active and specific sphingosine kinase-2 (SphK2) inhibitor (IC50: 60 μM).
Formula:
C23H25ClN2O
Purity:
98.86% - 99.85%
Color and Shape:
Solid
Molecular weight:
380.91
Ref: TM-T6750
| 1mg | 40.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 85.00 € | ||
| 10mg | 124.00 € | ||
| 25mg | 240.00 € | ||
| 50mg | 415.00 € | ||
| 100mg | 615.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
S1p receptor agonist 1
CAS:1514888-56-2
S1p receptor agonist 1 (S1p-receptor-agonist-1) is an S1P receptor agonist.
Formula:
C23H24FN3O3
Purity:
99.07% - 99.90%
Color and Shape:
Solid
Molecular weight:
409.45
Ref: TM-T4031
| 1mg | 47.00 € | ||
| 5mg | 127.00 € | ||
| 10mg | 197.00 € | ||
| 25mg | 354.00 € | ||
| 50mg | 540.00 € | ||
| 100mg | 743.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
SLM6031434 HCl
CAS:1897379-34-8
SLM6031434 HCl (SLM-6031434 HCl) is a SphK2 inhibitor that reduces LPS-induced TNF伪 and IL-1尾 production.
Formula:
C22H31ClF3N5O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
489.96
Ref: TM-T28806
| 1mg | 126.00 € | ||
| 5mg | 398.00 € | ||
| 10mg | 547.00 € |
Estimated delivery in United States, on Tuesday 3 Jun 2025
Ex26
CAS:1233332-37-0
Ex26 (S1P1-IN-Ex26) is an S1P1 antagonist used in experimental autoimmune encephalomyelitis, atherosclerosis, and gastric cancer.
Formula:
C28H28ClFN2O3
Purity:
99.62%
Color and Shape:
Solid
Molecular weight:
494.99
Ref: TM-T28643
| 1mg | 111.00 € | ||
| 5mg | 269.00 € | ||
| 10mg | 432.00 € | ||
| 25mg | 697.00 € | ||
| 50mg | 938.00 € | ||
| 100mg | 1,293.00 € |
Estimated delivery in United States, on Tuesday 3 Jun 2025
ASP-4058
CAS:952565-91-2
ASP-4058: Safe, oral S1P1/S1P5 agonist; improves autoimmune encephalomyelitis in mice.
Formula:
C19H12F6N4O2
Purity:
99.5% - 99.51%
Color and Shape:
Solid
Molecular weight:
442.31
Ref: TM-T10385
| 1mg | 99.00 € | ||
| 5mg | 235.00 € | ||
| 10mg | 376.00 € | ||
| 25mg | 680.00 € | ||
| 50mg | 932.00 € | ||
| 100mg | 1,311.00 € |
Estimated delivery in United States, on Tuesday 3 Jun 2025
CYM50374
CAS:1314212-81-1
CYM50374 inhibits Sphingosine-1-phosphate receptor 4 (S1P4 ) with an IC50 of µM.
Formula:
C19H19NO3S
Purity:
98.4% - 98.49%
Color and Shape:
Solid
Molecular weight:
341.42
Ref: TM-T27106
| 1mg | 333.00 € | ||
| 5mg | 787.00 € | ||
| 10mg | 1,074.00 € | ||
| 25mg | 1,510.00 € | ||
| 50mg | 1,882.00 € | ||
| 100mg | 2,375.00 € | ||
| 500mg | 4,655.00 € |
Estimated delivery in United States, on Tuesday 3 Jun 2025
Amgen-23
CAS:1448706-15-7
Amgen-23 is a selective and highly potent sphingosine kinase 1 (SPHK1) inhibitor that inhibits SPHK2 …
Formula:
C23H25Cl2N3O2S
Purity:
97.31%
Color and Shape:
Liquid
Molecular weight:
478.44
Ref: TM-T63132
| 1mg | 92.00 € | ||
| 5mg | 188.00 € | ||
| 10mg | 321.00 € | ||
| 25mg | 645.00 € | ||
| 50mg | 947.00 € | ||
| 100mg | 1,644.00 € |
Estimated delivery in United States, on Tuesday 3 Jun 2025
VPC 23019
CAS:449173-19-7
VPC 23019 is a competitive antagonist at the S1P1 and S1P3 receptors (pKi= 7.86 and …
Formula:
C17H29N2O5P
Purity:
98%
Color and Shape:
Solid
Molecular weight:
372.4
Ref: TM-T17237
| 25mg | 630.00 € | ||
| 50mg | 820.00 € | ||
| 100mg | 1,225.00 € |
Estimated delivery in United States, on Tuesday 3 Jun 2025
K6PC-5
CAS:756875-51-1
K6PC-5 is a ceramide derivative that acts as an activator of sphingosine kinase 1 (SPHK1), …
Formula:
C19H37NO4
Purity:
98.55%
Color and Shape:
Solid
Molecular weight:
343.5
Ref: TM-T27710
| 1mg | 40.00 € | ||
| 5mg | 88.00 € | ||
| 10mg | 126.00 € | ||
| 25mg | 274.00 € | ||
| 50mg | 449.00 € | ||
| 100mg | 658.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Tuesday 3 Jun 2025
LX-2931
CAS:948840-25-3
LX-2931(LX-3305) is a sphingosine-1-phosphate cleavage enzyme (S1P) inhibitor for the treatment of rheumatoid arthritis.
Formula:
C9H15N3O5
Purity:
100% - 99.83%
Color and Shape:
Solid
Molecular weight:
245.23
Ref: TM-T27864
| 1mg | 245.00 € | ||
| 5mg | 610.00 € | ||
| 10mg | 868.00 € | ||
| 25mg | 1,301.00 € | ||
| 50mg | 1,758.00 € |
Estimated delivery in United States, on Tuesday 3 Jun 2025
SK1-IN-1
CAS:1218816-71-7
SK1-IN-1 is a SPHK1 inhibitor (IC50: 58 nM), with potential anticancer activity, and can be …
Formula:
C22H30N4O3
Purity:
98.72%
Color and Shape:
Solid
Molecular weight:
398.5
Ref: TM-T12927
| 1mg | 205.00 € | ||
| 1mL*10mM (DMSO) | 289.00 € |
Estimated delivery in United States, on Tuesday 3 Jun 2025
SLP9101555
SLP9101555 is a potent and selective sphingosine kinase 2 (SphK2) inhibitor with a Ki of …
Formula:
C16H22BrClN2
Purity:
99%
Color and Shape:
Liquid
Molecular weight:
357.72
Ref: TM-T63047
| 1mg | 333.00 € | ||
| 5mg | 787.00 € | ||
| 10mg | 1,074.00 € | ||
| 25mg | 1,510.00 € | ||
| 50mg | 1,882.00 € | ||
| 100mg | 2,375.00 € | ||
| 500mg | 4,655.00 € | ||
| 1mL*10mM (DMSO) | 663.00 € |
Estimated delivery in United States, on Tuesday 3 Jun 2025
Cenerimod
CAS:1262414-04-9
Cenerimod (ACT-334441) is an S1P1 agonist used in the study of murine experimental autoimmune encephalomyelitis …
Formula:
C25H31N3O5
Purity:
97.43% - 99.97%
Color and Shape:
Solid
Molecular weight:
453.53
Ref: TM-T14924
| 2mg | 42.00 € | ||
| 5mg | 62.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 153.00 € | ||
| 50mg | 216.00 € | ||
| 1mL*10mM (DMSO) | 67.00 € |
Estimated delivery in United States, on Tuesday 17 Jun 2025
TASP 0277308
CAS:945725-50-8
NH2-UAMC1110 TFA is an aminobutoxy derivative of UAMC1110 used in the synthesis of FAPI-QS. UAMC1110 …
Formula:
C23H28Cl2N6O3S
Color and Shape:
Solid
Molecular weight:
539.48
Ref: TM-T41145
| 1mg | 259.00 € | ||
| 5mg | 635.00 € |
Estimated delivery in United States, on Tuesday 17 Jun 2025
BMS-960
CAS:1265321-86-5
BMS-960 is an S1P agonist with potential anti-tumour activity for cancer research.
Formula:
C26H23F3N4O5
Purity:
97.74% - 99.28%
Color and Shape:
Solid
Molecular weight:
528.48
Ref: TM-T26866
| 1mg | 712.00 € | ||
| 5mg | 1,483.00 € | ||
| 25mg | 2,688.00 € | ||
| 50mg | 4,019.00 € |
Estimated delivery in United States, on Tuesday 17 Jun 2025
AMG-369
CAS:1202073-26-4
AMG-369 (AMG 247) is an S1P1/S1P5 dual agonist that delays the development of experimental autoimmune …
Formula:
C26H22FN3O2S
Purity:
98.39%
Color and Shape:
Solid
Molecular weight:
459.54
Ref: TM-T29971
| 1mg | 393.00 € |
Estimated delivery in United States, on Tuesday 15 Jul 2025
SAR-114137
CAS:537706-31-3
SAR-114137 is a histone sphingomyelin kinase inhibitor used in the study of molluscum arteriosum and …
Formula:
C25H34N4O7S
Purity:
100% - 99.57%
Color and Shape:
Solid
Molecular weight:
534.63
Ref: TM-T28658
| 1mg | 465.00 € | ||
| 5mg | 1,074.00 € | ||
| 10mg | 1,454.00 € | ||
| 25mg | 2,157.00 € | ||
| 50mg | 2,832.00 € |
Estimated delivery in United States, on Tuesday 15 Jul 2025
