DNA/RNA Synthesis
Inhibitors of DNA and RNA synthesis are compounds that interfere with the replication and transcription processes in cells, thereby preventing the production of essential genetic material. These inhibitors can target various enzymes and proteins involved in nucleic acid synthesis, making them valuable tools for studying the mechanisms of replication, transcription, and translation. They are also used in developing treatments for infections and cancer. At CymitQuimica, we offer a broad spectrum of DNA/RNA synthesis inhibitors to support your research in molecular biology, virology, and therapeutic development.
Found 707 products of "DNA/RNA Synthesis"
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COH29
CAS:<p>COH29 is an oral RNR-blocking thiazole that may reduce DNA synthesis and promote apoptosis, with potential cancer-treating properties.</p>Formula:C22H16N2O5SPurity:97.04% - 98.92%Color and Shape:SolidMolecular weight:420.44Tempo
CAS:<p>Tempo (2,2,6,6-Tetramethylpiperidinooxy) has a wide range of applications including use as a free radical scavenger, a reagent in organic synthesis and as a</p>Formula:C9H18NOPurity:98.35%Color and Shape:Orange Crystals Or PowderMolecular weight:156.25Fialuridine
CAS:<p>Fialuridine (DRG-0098), a DNA polymerase inhibitor, shows strong anti-HBV effects both in vitro and in vivo.</p>Formula:C9H10FIN2O5Purity:99.71% - 99.88%Color and Shape:Less Crystals Colourless CrystalsMolecular weight:372.09TH287 hydrochloride
CAS:<p>TH287 inhibits MTH1 (IC50: 0.8 nM), causing DNA damage in cancer cells through oxidized dNTP incorporation, leading to cytotoxicity in mouse xenografts.</p>Formula:C11H11Cl3N4Purity:>99.99%Color and Shape:SolidMolecular weight:305.59Neobavaisoflavone
CAS:<p>Neobavaisoflavone: DNA polymerase inhibitor, potential for treating bone loss, anti-inflammatory, reduces ROS, RNS, cytokines in macrophages.</p>Formula:C20H18O4Purity:99.31% - 99.87%Color and Shape:SolidMolecular weight:322.352'-O-(2-Methoxyethyl)adenosine
CAS:<p>2'-O-(2-Methoxyethyl)adenosine is a nucleoside analog used to improve RNA target affinity and nuclease resistance of therapeutic oligonucleotides in preclin.</p>Formula:C13H19N5O5Purity:99.35%Color and Shape:SolidMolecular weight:325.32PolQi2
CAS:<p>PolQi2 is a Polθ inhibitor that suppresses the helicase activity of Polθ, and when combined with AZD7648.</p>Formula:C21H16ClN5O3SPurity:99.19%Color and Shape:SolidMolecular weight:453.95-Bromouridine
CAS:<p>5-Bromouridine is a antitumor uracil derivative that induces apoptosis in cancer cells by inhibiting DNA synthesis and is also a marker for DNA and RNA.</p>Formula:C9H11BrN2O6Purity:99.89%Color and Shape:White PowderMolecular weight:323.1DHX9-IN-8
CAS:<p>DHX9-IN-8 (Compound 6) functions as an inhibitor of the RNA helicase DHX9, exhibiting an EC50 of 3.4 μM for cellular target engagement within DHX9. It is primarily utilized in cancer research [1].</p>Formula:C18H16N2O3S2Color and Shape:SolidMolecular weight:372.46VVD-214
CAS:<p>VVD-214 (RO7589831) is a WRN deconjugation enzyme lethal-mutagenic inhibitor that can be used to study proliferative diseases.</p>Formula:C20H21F2N3O4SPurity:99.24%Color and Shape:SoildMolecular weight:437.46Metribuzin
CAS:<p>Metribuzin is a selective herbicide used on crops like soybeans and potatoes. It inhibits photosynthesis and is a persistent groundwater contaminant.</p>Formula:C8H14N4OSPurity:99.07%Color and Shape:Colorless Crytals Metribuzin Is A Colorless Crystalline Solid Used As An Herbicide (Niosh 2016)Molecular weight:214.29Locked nucleic acid 1
CAS:<p>Locked nucleic acid 1 is an LNA-type nucleoside derivative.</p>Formula:C32H32N2O8Purity:98%Color and Shape:SolidMolecular weight:572.61GSK4418959
CAS:<p>GSK4418959 (IDE275) is a selective WRN helicase inhibitor that blocks ATPase and DNA unwinding, serving as a tool in MSI-H cancer research.</p>Formula:C31H30F4N4O5SPurity:99.141%Color and Shape:SoildMolecular weight:646.65E-982
CAS:<p>E-982 is derived from the reference compound.</p>Formula:C25H31NO6SPurity:98%Color and Shape:SolidMolecular weight:473.582'-Azido-2'-deoxyuridine
CAS:<p>2'-Azido-2'-deoxyuridine (N3dUrd) is a ribonucleotide reductase inhibitor with anti-cancer activity.</p>Formula:C9H11N5O5Purity:98%Color and Shape:SolidMolecular weight:269.21RI(dl)-2 TFA
CAS:RI(dl)-2 TFA inhibits RAD51 D-loop at 11.1 μM and HR in human cells at 3.0 μM.Formula:C19H17N3Color and Shape:SolidMolecular weight:287.363,4-Dihydroxybenzylamine hydrobromide
CAS:<p>3,4-Dihydroxybenzylamine hydrobromide inhibits DNA polymerase and melanoma growth, varying with tyrosinase activity.</p>Formula:C7H10BrNO2Purity:98.49%Color and Shape:Light Beige Crystalline PowderMolecular weight:220.06E3330
CAS:<p>E3330 is a potent and selective APE1(Ref-1) inhibitor, which suppressed NF-kappa B DNA-binding activity.</p>Formula:C21H30O6Purity:99.52%Color and Shape:SolidMolecular weight:378.46Halofuginone
CAS:<p>Halofuginone (RU-19110) inhibits prolyl-tRNA synthetase (Ki=18.3 nM), down-regulates Smad3, and blocks TGF-β at 10 ng/ml.</p>Formula:C16H17BrClN3O3Purity:99.53%Color and Shape:Off-White SolidMolecular weight:414.68Thiarabine
CAS:<p>Thiarabine displays effective anti-tumor activity. It also inhibition of DNA synthesis.</p>Formula:C9H13N3O4SPurity:98%Color and Shape:SolidMolecular weight:259.28BzDANP
CAS:<p>BzDANP is a modulator of pre-miR-29a maturation by Dicer.</p>Formula:C18H24N6Color and Shape:SolidMolecular weight:324.42SPC-839
CAS:<p>SPC-839 is an IKK-2 Inhibitor with oral activity.</p>Formula:C18H14N4O3SColor and Shape:SolidMolecular weight:366.39SEC inhibitor KL-2
CAS:<p>KL-2: potent SEC inhibitor, selectively disrupts AFF4-CCNT1, dose-dependent, Ki: 1.50 μM.</p>Formula:C17H13ClFNO3Purity:99.86%Color and Shape:SolidMolecular weight:333.74MTH1-IN-2
CAS:<p>MTH1-IN-2 is an inhibitor of MutT homolog 1 (MTH1), with anti-tumor activity.</p>Formula:C24H27N3O5SPurity:98%Color and Shape:SolidMolecular weight:469.55AM-TS23
CAS:<p>AM-TS23 is used as a DNA polymerase lambda and beta inhibitor.</p>Formula:C17H12N2O3S3Purity:98%Color and Shape:SolidMolecular weight:388.48ML366
CAS:<p>ML366 is a Vibrio cholerae Quorum Sensing inhibitor Acting via the LuxO response regulator.</p>Formula:C17H19N3O4Purity:98%Color and Shape:SolidMolecular weight:329.35Meturedepa
CAS:<p>Meturedepa is an antineoplastic agent.</p>Formula:C11H22N3O3PPurity:98%Color and Shape:SolidMolecular weight:275.288-Azido-ADP disodium
CAS:<p>8-Azido-ADP (disodium) is a covalent inhibitor of ADP/ATP exchange in mitochondria, causing irreversible inhibition in light.</p>Formula:C10H13N8NaO10P2Color and Shape:SolidMolecular weight:490.197S-(N-PhenethylthiocarbaMoyl)-L-cysteine
CAS:<p>PEITC-Cys: anticarcinogenic, antileukemic, inhibits DNA synthesis in HL60, P450 inhibitor.</p>Formula:C12H16N2O2S2Color and Shape:SolidMolecular weight:284.42-Keto-D-galactose
CAS:<p>2-Keto-D-galactose inhibits DNA synthesis and inhibits the proliferation of in vitro grown Ehrlich ascites tumor cells.</p>Formula:C6H10O6Purity:98%Color and Shape:SolidMolecular weight:178.14DHX9-IN-1
CAS:<p>DHX9-IN-1 is a potent ATP-dependent RNA helicase A (DHX9) inhibitor, exhibiting an IC50 of 9.45 nM and demonstrating antitumor activity [1].</p>Formula:C21H21F2N5O3SColor and Shape:SolidMolecular weight:461.49Direct Black 38 free acid
CAS:<p>Ferristatin II (Direct Black 38 free acid) is a polysulphonated dye and promotes the degradation of transferrin receptor-1 in vitro and in vivo.</p>Formula:C34H27N9O7S2Purity:98%Color and Shape:SolidMolecular weight:737.77Crisnatol
CAS:<p>Crisnatol (BWA770U) is an oral anticancer DNA intercalator, toxic to breast cancer cells, not skin fibroblasts.</p>Formula:C23H23NO2Color and Shape:SolidMolecular weight:345.43Codon readthrough inducer 1
CAS:<p>Codon readthrough inducer 1 contains pyrimidine bases and shows good readthrough activity.</p>Formula:C15H11N3O5Purity:98%Color and Shape:SolidMolecular weight:313.26MS0017509
CAS:<p>MS0017509 is a DNA damage repair inhibitor.</p>Formula:C11H10N4Purity:98%Color and Shape:SolidMolecular weight:198.22CTP Synthetase-IN-1
CAS:<p>CTP Synthetase-IN-1 is a cytidine 5'-triphosphate synthetase (CTPS) inhibitor with antitumor activity for the study of arthritis and rheumatoid arthritis.</p>Formula:C20H19F3N6O3S2Purity:98.11% - 99.18%Color and Shape:SolidMolecular weight:512.53DENV-IN-4
CAS:<p>DENV-IN-4: Effective DENV inhibitor (EC50=4.79 μM), low toxicity (CC50>100 μM), and strong selectivity (SI>20.9); suppresses DENV2 and RdRp.</p>Formula:C28H32N4O4SiColor and Shape:SolidMolecular weight:516.66JNJ-9676
CAS:<p>JNJ-9676 is an orally active inhibitor of the coronavirus membrane protein, thereby blocking viral assembly and release.coronavirus and SARS-CoV.</p>Formula:C28H21F2N5O2Purity:99.83%Color and Shape:SoildMolecular weight:497.5IDD388
CAS:<p>IDD388 is a selective and potent aldose reductase (ALR2) inhibitor with antitumor activity that inhibits the ALR1 receptor.</p>Formula:C16H12BrClFNO4Purity:99.56%Color and Shape:SolidMolecular weight:416.63TDRL-X80
CAS:<p>TDRL-X80 inhibits XPA DNA binding; effective on single, double, and cisplatin-damaged DNA; IC50: 18-29 μM (FP), 21-39 μM (ELISA).</p>Formula:C23H15ClN2O6Color and Shape:SolidMolecular weight:450.833'-Deoxyuridine-5'-triphosphate
CAS:<p>3'-dUTP, a nucleotide analogue, competitively inhibits RNA polymerases I & II, with a Ki of 2.0 µM.</p>Formula:C9H15N2O14P3Color and Shape:SolidMolecular weight:468.14ST7612AA1
CAS:<p>ST7612AA1: potent, oral HDAC inhibitor; reactivates HIV-1 latency; shows antitumor effects; may study malaria.</p>Formula:C20H27N3O4SPurity:99.71%Color and Shape:SolidMolecular weight:405.51Apricitabine
CAS:<p>Apricitabine (SPD754) is a highly selective and orally active HIV-1 reverse transcriptase inhibitor (Ki=0.08 μM), the (-) enantiomer of 2′-deoxy-3′-oxy-4′-</p>Formula:C8H11N3O3SPurity:99.45%Color and Shape:SolidMolecular weight:229.26Werner syndrome RecQ helicase-IN-4
CAS:<p>Werner syndrome RecQ helicase-IN-4 is a WRN inhibitor with anticancer and anti-proliferative activity, used in colorectal and gastric cancer research.</p>Formula:C32H33F3N8O5Purity:98.27%Color and Shape:SolidMolecular weight:666.65DDD100097
CAS:<p>DDD100097 is a N-myristoyltransferase inhibitor with potential inhibitory effects on Trypanosoma brucei, which can be used to study neurological disorders.</p>Formula:C22H30Cl2F2N4O2SPurity:98.89%Color and Shape:SolidMolecular weight:523.47CM03
CAS:<p>CM03 is a cell-selective G-quadruplex ligand with anti-cancer activity, stabilizing G4 genes, useful in pancreatic cancer research.</p>Formula:C34H44N6O6Purity:98.65%Color and Shape:SolidMolecular weight:632.75Nitracrine
CAS:<p>Nitracrine: a 1-nitroacridine, hypoxia-selective, anti-tumor agent; inhibits RNA synthesis, binds DNA reversibly and forms covalent adducts.</p>Formula:C18H20N4O2Purity:98%Color and Shape:SolidMolecular weight:324.38Laromustine
CAS:<p>Laromustine (VNP40101M) is a sulfonyl hydrolysis alkylation prodrug for cancer treatment with significant anticancer activity, inhibiting thioredoxin reductase.</p>Formula:C6H14ClN3O5S2Purity:≥98%Color and Shape:SolidMolecular weight:307.7810-Formyl-5,8-dideazafolic acid
CAS:<p>10-Formyl-5,8-dideazafolic acid is a thymidylate synthase inhibitor.</p>Formula:C22H21N5O7Purity:96.04%Color and Shape:SolidMolecular weight:467.43CID 5951923
CAS:<p>CID 5951923 is an inhibitor of KLF5 transcription factor with an IC50 of 603 nM.</p>Formula:C16H18N2O7SPurity:99.95%Color and Shape:SolidMolecular weight:382.39
