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DNA/RNA Synthesis

DNA/RNA Synthesis

Inhibitors of DNA and RNA synthesis are compounds that interfere with the replication and transcription processes in cells, thereby preventing the production of essential genetic material. These inhibitors can target various enzymes and proteins involved in nucleic acid synthesis, making them valuable tools for studying the mechanisms of replication, transcription, and translation. They are also used in developing treatments for infections and cancer. At CymitQuimica, we offer a broad spectrum of DNA/RNA synthesis inhibitors to support your research in molecular biology, virology, and therapeutic development.

Found 707 products of "DNA/RNA Synthesis"

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  • Synucleozid

    CAS:
    <p>Synucleozid is a potent the SNCA mRNA inhibitor that encodes α-synuclein protein (IC50=1.5 μM), has the potential for the investigation of Parkinson’s disease.</p>
    Formula:C22H20N6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:368.43
  • Glucocorticoid receptor modulator 1

    CAS:
    <p>Glucocorticoid receptor modulator 1 is a orally NF-κB and AP-1 inhibitor, inflammatory factors IL-6, IL-1β, TNF-α, and MMP-13, alleviating skin inflammation.</p>
    Formula:C24H23ClN2O4S
    Purity:99.79%
    Color and Shape:Solid
    Molecular weight:470.97
  • Bofumustine

    CAS:
    <p>Bofumustine is a chloroethyl nitrosourea with anti tumor properties.</p>
    Formula:C18H21ClN4O9
    Color and Shape:Solid
    Molecular weight:472.83
  • BMVC

    CAS:
    <p>BMVC is a potent G-quadruplex (G4) stabilizer and a selective telomerase inhibitor (IC50: ~0.2 μM) with anticancer activities.</p>
    Formula:C28H25I2N3
    Color and Shape:Solid
    Molecular weight:657.33
  • Picoplatin

    CAS:
    <p>Picoplatin, an anti-cancer agent overcoming platinum resistance, alkylates DNA to block replication, transcription, and induce apoptosis.</p>
    Formula:C6H10Cl2N2Pt
    Purity:98%
    Color and Shape:Solid
    Molecular weight:376.14
  • HHL-6

    CAS:
    <p>HHL-6 is a c-Fos and BDNF protein expression modulator.</p>
    Formula:C19H26N2O3
    Color and Shape:Solid
    Molecular weight:330.42
  • Fozivudine tidoxil

    CAS:
    <p>Fozivudine tidoxil, a reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.</p>
    Formula:C35H64N5O8PS
    Color and Shape:Solid
    Molecular weight:745.95
  • Werner syndrome RecQ helicase-IN-3

    CAS:
    <p>Potent WRN inhibitor, Werner syndrome RecQ helicase-IN-3, is orally active with 0.06 µM IC50; exhibits antiproliferative and anticancer effects.</p>
    Formula:C31H30ClF3N8O5
    Color and Shape:Solid
    Molecular weight:687.07
  • 2-Fluoroadenine

    CAS:
    <p>2-Fluoroadenine (NSC-27364) has toxicity in nonproliferating and proliferating tumor cells. 2-Fluoroadenine can be used for anticancer studies.</p>
    Formula:C5H4FN5
    Purity:98.84% - 99.62%
    Color and Shape:White To Light Yellow Crystal Powder
    Molecular weight:153.12
  • D-Xylofuranose, 1,2,3,5-tetraacetate

    CAS:
    <p>1,2,3,5-Tetra-O-acetyl-D-xylofuranose is a starting material for the synthesis of nucleosides.</p>
    Formula:C13H18O9
    Color and Shape:Solid
    Molecular weight:318.28
  • Crisnatol mesylate

    CAS:
    <p>Crisnatol, a potent and selective DNA intercalator, has potential anticancer activity.</p>
    Formula:C24H27NO5S
    Color and Shape:Solid
    Molecular weight:441.54
  • HBV-IN-16

    CAS:
    <p>HBV-IN-16, a quinoline derivative, inhibits HBV cccDNA, key for viral replication (from patent WO2019121357A1).</p>
    Formula:C22H20ClNO4
    Color and Shape:Solid
    Molecular weight:397.85
  • GW8510

    CAS:
    <p>GW8510 is a CDK2 and RRM2 inhibitor that affects DNA synthesis and antiproliferation in tumor cells. In mammalian aging models, GW851 prolongs lifespan.</p>
    Formula:C21H15N5O3S2
    Purity:99.32%
    Color and Shape:Solid
    Molecular weight:449.51
  • AB-182

    CAS:
    <p>AB-182 is an aziridine derivative with antitumor activity.</p>
    Formula:C11H22N3O4P
    Color and Shape:Solid
    Molecular weight:291.28
  • BPIC

    CAS:
    <p>BPIC is an agent of anti-tumor that acts by inhibiting inflammation and scavenging free radicals.</p>
    Formula:C27H20N2O5
    Color and Shape:Solid
    Molecular weight:452.46
  • HBV-IN-22

    CAS:
    <p>HBV-IN-22 (Compound LC5f) is an HBV DNA replication inhibitor that acts on both wild-type HBV (IC50: 0.71 μM) and drug-resistant HBV (IC50: 0.84 μM).</p>
    Formula:C26H29N3O2S2
    Color and Shape:Solid
    Molecular weight:479.66
  • Braco-19 trihydrochloride

    CAS:
    <p>BRACO19 3HCl inhibits telomerase, blocking its capping function, and prevents HAdV viral replication.</p>
    Formula:C35H46Cl3N7O2
    Purity:98.74%
    Color and Shape:Solid
    Molecular weight:703.14
  • Datelliptium chloride

    CAS:
    <p>Datelliptium chloride is a DNA-intercalating agent derived from ellipticine. Datelliptium chloride shows anti-tumor activities.</p>
    Formula:C23H28ClN3O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:397.94
  • UIAA-II-232

    CAS:
    <p>UIAA-II-232 (compound 19b) is a potent inhibitor of DNA gyrase catalytic (IC 50= 3.5 μM).</p>
    Formula:C20H24FN5O3
    Color and Shape:Solid
    Molecular weight:401.43
  • RHI002-Me

    CAS:
    <p>RHI002-Me is a methylated derivative of RHI002, a selective inhibitor of human RNaseH2.</p>
    Formula:C18H19N3O2S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:373.49
  • Antitumor agent-84


    <p>Antitumor agent-84 stabilizes G-quadruplex DNA, exhibits potent anti-tumor effects.</p>
    Formula:C24H31N7
    Color and Shape:Solid
    Molecular weight:417.55
  • Beaucage reagent

    CAS:
    <p>Beaucage reagent, which is found to be effective in causing DNA cleavage.</p>
    Formula:C7H4O3S2
    Purity:98.50%
    Color and Shape:White To Off-White Powder
    Molecular weight:200.23
  • CGP 53353

    CAS:
    <p>CGP 53353 (DAPH-7) is a PKC inhibitor with inhibitory effects on PKCβII and PKCβI and can be used to study atherosclerosis.</p>
    Formula:C20H13F2N3O2
    Purity:98.11%
    Color and Shape:Solid
    Molecular weight:365.33
  • Homocarbonyltopsentin

    CAS:
    <p>Homocarbonyltopsentin: Small molecule, binds TSL2 pentaloops, enhances SMN2 E7 splicing, EC50 16 μM.</p>
    Formula:C21H14N4O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:370.36
  • Triaziquone

    CAS:
    <p>Triaziquone is an alkylating agent that can react with DNA to form intrastrand crosslinks.</p>
    Formula:C12H13N3O2
    Color and Shape:Solid
    Molecular weight:231.25
  • Phelorphan

    CAS:
    <p>Phelorphan is an inhibitor of enkephalinase.</p>
    Formula:C20H22N2O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:386.46
  • MLAF50

    CAS:
    <p>MLAF50 is an inhibitor of the REV1 UBM2-Ubiquitin interaction.</p>
    Formula:C15H12I2O4
    Color and Shape:Solid
    Molecular weight:510.06
  • JFN05510

    CAS:
    <p>Compound: 3'-O-tert-BDMS-5'-O-DMT-N2-IBG 2'-CE phosphoramidite; has anticancer properties and activates enzymes.</p>
    Formula:C50H68N7O9PSi
    Color and Shape:Solid
    Molecular weight:970.18
  • BMH-22

    CAS:
    <p>BMH-22 is an RNA polymerase I inhibitor that acts by causing nucleolar stress and showing potent anticancer activity across many tumor types.</p>
    Formula:C16H17N3
    Color and Shape:Solid
    Molecular weight:251.33
  • Phen-DC3

    CAS:
    <p>Phen-DC3 is a G-quadruplex (G4) specific ligand which can inhibit FANCJ and DinG helicases (IC50s of 65±6 and 50±10 nM, respectively).</p>
    Formula:C34H26N6O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:550.61
  • Zelpolib

    CAS:
    <p>Zelpolib is a specific inhibitor of DNA polymerase δ (Pol δ), inhibiting DNA replication. antiproliferative.</p>
    Formula:C22H21N3O5S2
    Purity:98.79%
    Color and Shape:Solid
    Molecular weight:471.55
  • HBV-IN-4

    CAS:
    <p>HBV-IN-4, a phthalazinone, inhibits HBV DNA replication orally (IC50: 14 nM), encouraging genome-free capsids with strong anti-HBV effects.</p>
    Formula:C24H19ClFN5O3
    Color and Shape:Solid
    Molecular weight:479.89
  • AS-136A

    CAS:
    <p>AS-136A is an orally active MV RdRp inhibitor with antiviral activity that inhibits measles virus and blocks viral RNA synthesis.</p>
    Formula:C17H19F3N4O3S
    Purity:98.52%
    Color and Shape:Solid
    Molecular weight:416.42
  • HIPP

    CAS:
    <p>HIPP is a highly selective inhibitor of antineoplastic CtBP.</p>
    Formula:C9H9NO3
    Color and Shape:Solid
    Molecular weight:179.17
  • HIV-1 inhibitor-43

    CAS:
    <p>HIV-1 Inhibitor-43 suppresses HIV-1, with EC50: 21.3 nM (Y188L), 6.2 nM (K103N-Y181C), &lt;0.7 nM (K103N/Y181C), and lowers HIV RNA/p24 protein.</p>
    Formula:C24H21ClN2O4S
    Color and Shape:Solid
    Molecular weight:468.95
  • 360A iodide

    CAS:
    <p>360A iodide is a selective stabilizer of G-quadruplex and inhibits telomerase activity (IC50: 300 nM in TRAP-G4 assay).</p>
    Formula:C27H23I2N5O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:703.31
  • Cylindrospermopsin

    CAS:
    <p>Cylindrospermopsin: a toxic cyanobacterial uracil derivative, disrupts protein/glutathione synthesis in hepatocytes, and is genotoxic.</p>
    Formula:C15H21N5O7S
    Color and Shape:Solid
    Molecular weight:415.42
  • BAY-707

    CAS:
    <p>BAY-707: tolerable in mice, no anticancer efficacy; potent, selective MTH1 inhibitor, IC50 = 2.3 nM; good PK profile.</p>
    Formula:C15H20N4O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:288.34
  • EGFR/HER2/TS-IN-2

    CAS:
    <p>EGFR/HER2/TS-IN-2: Strong EGFR, HER2 &amp; TS inhibitor; EGFR IC50=0.173μM, HER2 IC50=0.125μM, TS IC50=1.12μM; kills MDA-MB-231 cells (IC50=1.69μM).</p>
    Formula:C26H21N7OS2
    Color and Shape:Solid
    Molecular weight:511.62
  • FLDP-5

    CAS:
    <p>FLDP-5: BBB-penetrant curcuminoid, induces ROS, DNA damage, S phase arrest, suppresses tumors in LN-18 cells.</p>
    Formula:C21H21NO5
    Color and Shape:Solid
    Molecular weight:367.4
  • HBV-IN-21

    CAS:
    <p>HBV-IN-21 inhibits HBV DNA replication (IC50: 2.2 μM) and binds HBV capsid protein well (KD: 60.0 μM).</p>
    Formula:C17H17FN4OS2
    Color and Shape:Solid
    Molecular weight:376.47
  • 15(S)-HpETE

    CAS:
    <p>15(S)-HpETE is a product of arachidonic acid formed in the 15-lipoxygenase pathway and inhibits angiogenesis.</p>
    Formula:C20H32O4
    Color and Shape:Solid
    Molecular weight:336.47
  • NPD9948

    CAS:
    <p>NPD9948 is a competitive inhibitor of MTH1.</p>
    Formula:C13H14N6
    Color and Shape:Solid
    Molecular weight:254.29
  • CAY10760

    CAS:
    <p>CAY10760 inhibits RAD51-BRCA2 interaction (EC50=19 μM), reduces homologous recombination by 54%, and hinders BxPC-3/Capan-1 cancer cell proliferation.</p>
    Formula:C28H24ClN3O3
    Color and Shape:Solid
    Molecular weight:485.96
  • BMH-23

    CAS:
    <p>BMH-23 is an RNA polymerase I inhibitor that acts by causing nucleolar stress and showing potent anticancer activity across many tumor types.</p>
    Formula:C15H15N3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:237.3
  • ERCC1-XPF-IN-1

    CAS:
    <p>ERCC1-XPF-IN-1: potent ERCC1-XPF inhibitor (IC50: 0.49 μM), hampers CPD removal, boosts UV toxicity, hinders DNA repair.</p>
    Formula:C28H32ClN5O2
    Color and Shape:Solid
    Molecular weight:506.04
  • Halofuginone hydrobromide

    CAS:
    <p>Halofuginone specifically inhibits collagen type I and MMP-2 gene expression, which may result in the suppression of angiogenesis and tumor cell growth.</p>
    Formula:C16H17BrClN3O3·HBr
    Purity:97.01% - 99.73%
    Color and Shape:Solid
    Molecular weight:495.59
  • Enocitabine

    CAS:
    <p>Enocitabine is a nucleoside analog.</p>
    Formula:C31H55N3O6
    Purity:97.22%
    Color and Shape:Solid
    Molecular weight:565.78
  • cp028

    CAS:
    <p>cp028 inhibits pre-mRNA splicing in vitro.</p>
    Formula:C23H17FN2O4
    Color and Shape:Solid
    Molecular weight:404.39
  • IACS-4759

    CAS:
    <p>IACS-4759 is a novel potent and selective MTH1 inhibitor with excellent cell permeability and good metabolic stability in microsomes.</p>
    Formula:C10H17N3O2
    Color and Shape:Solid
    Molecular weight:211.26