
DNA/RNA Synthesis
Inhibitors of DNA and RNA synthesis are compounds that interfere with the replication and transcription processes in cells, thereby preventing the production of essential genetic material. These inhibitors can target various enzymes and proteins involved in nucleic acid synthesis, making them valuable tools for studying the mechanisms of replication, transcription, and translation. They are also used in developing treatments for infections and cancer. At CymitQuimica, we offer a broad spectrum of DNA/RNA synthesis inhibitors to support your research in molecular biology, virology, and therapeutic development.
Found 707 products of "DNA/RNA Synthesis"
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Synucleozid
CAS:<p>Synucleozid is a potent the SNCA mRNA inhibitor that encodes α-synuclein protein (IC50=1.5 μM), has the potential for the investigation of Parkinson’s disease.</p>Formula:C22H20N6Purity:98%Color and Shape:SolidMolecular weight:368.43Glucocorticoid receptor modulator 1
CAS:<p>Glucocorticoid receptor modulator 1 is a orally NF-κB and AP-1 inhibitor, inflammatory factors IL-6, IL-1β, TNF-α, and MMP-13, alleviating skin inflammation.</p>Formula:C24H23ClN2O4SPurity:99.79%Color and Shape:SolidMolecular weight:470.97Bofumustine
CAS:<p>Bofumustine is a chloroethyl nitrosourea with anti tumor properties.</p>Formula:C18H21ClN4O9Color and Shape:SolidMolecular weight:472.83BMVC
CAS:<p>BMVC is a potent G-quadruplex (G4) stabilizer and a selective telomerase inhibitor (IC50: ~0.2 μM) with anticancer activities.</p>Formula:C28H25I2N3Color and Shape:SolidMolecular weight:657.33Picoplatin
CAS:<p>Picoplatin, an anti-cancer agent overcoming platinum resistance, alkylates DNA to block replication, transcription, and induce apoptosis.</p>Formula:C6H10Cl2N2PtPurity:98%Color and Shape:SolidMolecular weight:376.14HHL-6
CAS:<p>HHL-6 is a c-Fos and BDNF protein expression modulator.</p>Formula:C19H26N2O3Color and Shape:SolidMolecular weight:330.42Fozivudine tidoxil
CAS:<p>Fozivudine tidoxil, a reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.</p>Formula:C35H64N5O8PSColor and Shape:SolidMolecular weight:745.95Werner syndrome RecQ helicase-IN-3
CAS:<p>Potent WRN inhibitor, Werner syndrome RecQ helicase-IN-3, is orally active with 0.06 µM IC50; exhibits antiproliferative and anticancer effects.</p>Formula:C31H30ClF3N8O5Color and Shape:SolidMolecular weight:687.072-Fluoroadenine
CAS:<p>2-Fluoroadenine (NSC-27364) has toxicity in nonproliferating and proliferating tumor cells. 2-Fluoroadenine can be used for anticancer studies.</p>Formula:C5H4FN5Purity:98.84% - 99.62%Color and Shape:White To Light Yellow Crystal PowderMolecular weight:153.12D-Xylofuranose, 1,2,3,5-tetraacetate
CAS:<p>1,2,3,5-Tetra-O-acetyl-D-xylofuranose is a starting material for the synthesis of nucleosides.</p>Formula:C13H18O9Color and Shape:SolidMolecular weight:318.28Crisnatol mesylate
CAS:<p>Crisnatol, a potent and selective DNA intercalator, has potential anticancer activity.</p>Formula:C24H27NO5SColor and Shape:SolidMolecular weight:441.54HBV-IN-16
CAS:<p>HBV-IN-16, a quinoline derivative, inhibits HBV cccDNA, key for viral replication (from patent WO2019121357A1).</p>Formula:C22H20ClNO4Color and Shape:SolidMolecular weight:397.85GW8510
CAS:<p>GW8510 is a CDK2 and RRM2 inhibitor that affects DNA synthesis and antiproliferation in tumor cells. In mammalian aging models, GW851 prolongs lifespan.</p>Formula:C21H15N5O3S2Purity:99.32%Color and Shape:SolidMolecular weight:449.51AB-182
CAS:<p>AB-182 is an aziridine derivative with antitumor activity.</p>Formula:C11H22N3O4PColor and Shape:SolidMolecular weight:291.28BPIC
CAS:<p>BPIC is an agent of anti-tumor that acts by inhibiting inflammation and scavenging free radicals.</p>Formula:C27H20N2O5Color and Shape:SolidMolecular weight:452.46HBV-IN-22
CAS:<p>HBV-IN-22 (Compound LC5f) is an HBV DNA replication inhibitor that acts on both wild-type HBV (IC50: 0.71 μM) and drug-resistant HBV (IC50: 0.84 μM).</p>Formula:C26H29N3O2S2Color and Shape:SolidMolecular weight:479.66Braco-19 trihydrochloride
CAS:<p>BRACO19 3HCl inhibits telomerase, blocking its capping function, and prevents HAdV viral replication.</p>Formula:C35H46Cl3N7O2Purity:98.74%Color and Shape:SolidMolecular weight:703.14Datelliptium chloride
CAS:<p>Datelliptium chloride is a DNA-intercalating agent derived from ellipticine. Datelliptium chloride shows anti-tumor activities.</p>Formula:C23H28ClN3OPurity:98%Color and Shape:SolidMolecular weight:397.94UIAA-II-232
CAS:<p>UIAA-II-232 (compound 19b) is a potent inhibitor of DNA gyrase catalytic (IC 50= 3.5 μM).</p>Formula:C20H24FN5O3Color and Shape:SolidMolecular weight:401.43RHI002-Me
CAS:<p>RHI002-Me is a methylated derivative of RHI002, a selective inhibitor of human RNaseH2.</p>Formula:C18H19N3O2S2Purity:98%Color and Shape:SolidMolecular weight:373.49Antitumor agent-84
<p>Antitumor agent-84 stabilizes G-quadruplex DNA, exhibits potent anti-tumor effects.</p>Formula:C24H31N7Color and Shape:SolidMolecular weight:417.55Beaucage reagent
CAS:<p>Beaucage reagent, which is found to be effective in causing DNA cleavage.</p>Formula:C7H4O3S2Purity:98.50%Color and Shape:White To Off-White PowderMolecular weight:200.23CGP 53353
CAS:<p>CGP 53353 (DAPH-7) is a PKC inhibitor with inhibitory effects on PKCβII and PKCβI and can be used to study atherosclerosis.</p>Formula:C20H13F2N3O2Purity:98.11%Color and Shape:SolidMolecular weight:365.33Homocarbonyltopsentin
CAS:<p>Homocarbonyltopsentin: Small molecule, binds TSL2 pentaloops, enhances SMN2 E7 splicing, EC50 16 μM.</p>Formula:C21H14N4O3Purity:98%Color and Shape:SolidMolecular weight:370.36Triaziquone
CAS:<p>Triaziquone is an alkylating agent that can react with DNA to form intrastrand crosslinks.</p>Formula:C12H13N3O2Color and Shape:SolidMolecular weight:231.25Phelorphan
CAS:<p>Phelorphan is an inhibitor of enkephalinase.</p>Formula:C20H22N2O4SPurity:98%Color and Shape:SolidMolecular weight:386.46MLAF50
CAS:<p>MLAF50 is an inhibitor of the REV1 UBM2-Ubiquitin interaction.</p>Formula:C15H12I2O4Color and Shape:SolidMolecular weight:510.06JFN05510
CAS:<p>Compound: 3'-O-tert-BDMS-5'-O-DMT-N2-IBG 2'-CE phosphoramidite; has anticancer properties and activates enzymes.</p>Formula:C50H68N7O9PSiColor and Shape:SolidMolecular weight:970.18BMH-22
CAS:<p>BMH-22 is an RNA polymerase I inhibitor that acts by causing nucleolar stress and showing potent anticancer activity across many tumor types.</p>Formula:C16H17N3Color and Shape:SolidMolecular weight:251.33Phen-DC3
CAS:<p>Phen-DC3 is a G-quadruplex (G4) specific ligand which can inhibit FANCJ and DinG helicases (IC50s of 65±6 and 50±10 nM, respectively).</p>Formula:C34H26N6O2Purity:98%Color and Shape:SolidMolecular weight:550.61Zelpolib
CAS:<p>Zelpolib is a specific inhibitor of DNA polymerase δ (Pol δ), inhibiting DNA replication. antiproliferative.</p>Formula:C22H21N3O5S2Purity:98.79%Color and Shape:SolidMolecular weight:471.55HBV-IN-4
CAS:<p>HBV-IN-4, a phthalazinone, inhibits HBV DNA replication orally (IC50: 14 nM), encouraging genome-free capsids with strong anti-HBV effects.</p>Formula:C24H19ClFN5O3Color and Shape:SolidMolecular weight:479.89AS-136A
CAS:<p>AS-136A is an orally active MV RdRp inhibitor with antiviral activity that inhibits measles virus and blocks viral RNA synthesis.</p>Formula:C17H19F3N4O3SPurity:98.52%Color and Shape:SolidMolecular weight:416.42HIPP
CAS:<p>HIPP is a highly selective inhibitor of antineoplastic CtBP.</p>Formula:C9H9NO3Color and Shape:SolidMolecular weight:179.17HIV-1 inhibitor-43
CAS:<p>HIV-1 Inhibitor-43 suppresses HIV-1, with EC50: 21.3 nM (Y188L), 6.2 nM (K103N-Y181C), <0.7 nM (K103N/Y181C), and lowers HIV RNA/p24 protein.</p>Formula:C24H21ClN2O4SColor and Shape:SolidMolecular weight:468.95360A iodide
CAS:<p>360A iodide is a selective stabilizer of G-quadruplex and inhibits telomerase activity (IC50: 300 nM in TRAP-G4 assay).</p>Formula:C27H23I2N5O2Purity:98%Color and Shape:SolidMolecular weight:703.31Cylindrospermopsin
CAS:<p>Cylindrospermopsin: a toxic cyanobacterial uracil derivative, disrupts protein/glutathione synthesis in hepatocytes, and is genotoxic.</p>Formula:C15H21N5O7SColor and Shape:SolidMolecular weight:415.42BAY-707
CAS:<p>BAY-707: tolerable in mice, no anticancer efficacy; potent, selective MTH1 inhibitor, IC50 = 2.3 nM; good PK profile.</p>Formula:C15H20N4O2Purity:98%Color and Shape:SolidMolecular weight:288.34EGFR/HER2/TS-IN-2
CAS:<p>EGFR/HER2/TS-IN-2: Strong EGFR, HER2 & TS inhibitor; EGFR IC50=0.173μM, HER2 IC50=0.125μM, TS IC50=1.12μM; kills MDA-MB-231 cells (IC50=1.69μM).</p>Formula:C26H21N7OS2Color and Shape:SolidMolecular weight:511.62FLDP-5
CAS:<p>FLDP-5: BBB-penetrant curcuminoid, induces ROS, DNA damage, S phase arrest, suppresses tumors in LN-18 cells.</p>Formula:C21H21NO5Color and Shape:SolidMolecular weight:367.4HBV-IN-21
CAS:<p>HBV-IN-21 inhibits HBV DNA replication (IC50: 2.2 μM) and binds HBV capsid protein well (KD: 60.0 μM).</p>Formula:C17H17FN4OS2Color and Shape:SolidMolecular weight:376.4715(S)-HpETE
CAS:<p>15(S)-HpETE is a product of arachidonic acid formed in the 15-lipoxygenase pathway and inhibits angiogenesis.</p>Formula:C20H32O4Color and Shape:SolidMolecular weight:336.47NPD9948
CAS:<p>NPD9948 is a competitive inhibitor of MTH1.</p>Formula:C13H14N6Color and Shape:SolidMolecular weight:254.29CAY10760
CAS:<p>CAY10760 inhibits RAD51-BRCA2 interaction (EC50=19 μM), reduces homologous recombination by 54%, and hinders BxPC-3/Capan-1 cancer cell proliferation.</p>Formula:C28H24ClN3O3Color and Shape:SolidMolecular weight:485.96BMH-23
CAS:<p>BMH-23 is an RNA polymerase I inhibitor that acts by causing nucleolar stress and showing potent anticancer activity across many tumor types.</p>Formula:C15H15N3Purity:98%Color and Shape:SolidMolecular weight:237.3ERCC1-XPF-IN-1
CAS:<p>ERCC1-XPF-IN-1: potent ERCC1-XPF inhibitor (IC50: 0.49 μM), hampers CPD removal, boosts UV toxicity, hinders DNA repair.</p>Formula:C28H32ClN5O2Color and Shape:SolidMolecular weight:506.04Halofuginone hydrobromide
CAS:<p>Halofuginone specifically inhibits collagen type I and MMP-2 gene expression, which may result in the suppression of angiogenesis and tumor cell growth.</p>Formula:C16H17BrClN3O3·HBrPurity:97.01% - 99.73%Color and Shape:SolidMolecular weight:495.59Enocitabine
CAS:<p>Enocitabine is a nucleoside analog.</p>Formula:C31H55N3O6Purity:97.22%Color and Shape:SolidMolecular weight:565.78cp028
CAS:<p>cp028 inhibits pre-mRNA splicing in vitro.</p>Formula:C23H17FN2O4Color and Shape:SolidMolecular weight:404.39IACS-4759
CAS:<p>IACS-4759 is a novel potent and selective MTH1 inhibitor with excellent cell permeability and good metabolic stability in microsomes.</p>Formula:C10H17N3O2Color and Shape:SolidMolecular weight:211.26
