DNA/RNA Synthesis
Inhibitors of DNA and RNA synthesis are compounds that interfere with the replication and transcription processes in cells, thereby preventing the production of essential genetic material. These inhibitors can target various enzymes and proteins involved in nucleic acid synthesis, making them valuable tools for studying the mechanisms of replication, transcription, and translation. They are also used in developing treatments for infections and cancer. At CymitQuimica, we offer a broad spectrum of DNA/RNA synthesis inhibitors to support your research in molecular biology, virology, and therapeutic development.
Found 802 products of "DNA/RNA Synthesis"
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5-BrdU
CAS:5-BrdU (Broxuridine) is a nucleoside analogue, detect proliferating cells and compete with thymidine for incorporation into DNA. High-Quality, Low-Cost!Formula:C9H11BrN2O5Purity:99.54% - 99.87%Color and Shape:Crystals From Absolute Ethanol Physical Description White Crystalline Powder (Ntp 1992)Molecular weight:307.1Datelliptium chloride hydrochloride
CAS:Datelliptium chloride hydrochloride is a DNA-intercalating agent derived from ellipticine. with anti-tumor activities.
Formula:C23H29Cl2N3OPurity:99.46%Color and Shape:SolidMolecular weight:434.4PolQi2
CAS:PolQi2 is a Polθ inhibitor that suppresses the helicase activity of Polθ, and when combined with AZD7648.Formula:C21H16ClN5O3SPurity:99.19%Color and Shape:SolidMolecular weight:453.9Ref: TM-T84770
1mg84.00€5mg170.00€10mg281.00€25mg542.00€50mg757.00€100mg1,044.00€1mL*10mM (DMSO)195.00€5'-O-DMT-N4-Bz-5-Me-dC
CAS:5'-O-DMT-N4-Bz-5-Me-dC (DMT-NBZ-5-METHYL DC) is a modified nucleoside used in the synthesis of nucleoside phosphoramidites.Formula:C38H37N3O7Purity:98.88%Color and Shape:SolidMolecular weight:647.725-Bromouridine
CAS:5-Bromouridine is a antitumor uracil derivative that induces apoptosis in cancer cells by inhibiting DNA synthesis and is also a marker for DNA and RNA.Formula:C9H11BrN2O6Purity:99.89%Color and Shape:White PowderMolecular weight:323.12'-O-(2-Methoxyethyl)adenosine
CAS:2'-O-(2-Methoxyethyl)adenosine is a nucleoside analog used to improve RNA target affinity and nuclease resistance of therapeutic oligonucleotides in preclin.Formula:C13H19N5O5Purity:99.35%Color and Shape:SolidMolecular weight:325.32VVD-214
CAS:VVD-214 (RO7589831) is a WRN deconjugation enzyme lethal-mutagenic inhibitor that can be used to study proliferative diseases.Formula:C20H21F2N3O4SPurity:99.24% - 99.93%Color and Shape:SoildMolecular weight:437.46Ref: TM-T85309
1mg69.00€5mg147.00€10mg224.00€25mg358.00€50mg512.00€100mg707.00€1mL*10mM (DMSO)164.00€Locked nucleic acid 1
CAS:Locked nucleic acid 1 is an LNA-type nucleoside derivative.Formula:C32H32N2O8Purity:98%Color and Shape:SolidMolecular weight:572.61GSK4418959
CAS:GSK4418959 (IDE275) is a selective WRN helicase inhibitor that blocks ATPase and DNA unwinding, serving as a tool in MSI-H cancer research.Formula:C31H30F4N4O5SPurity:99.141%Color and Shape:SoildMolecular weight:646.65DHX9-IN-8
CAS:DHX9-IN-8 (Compound 6) functions as an inhibitor of the RNA helicase DHX9, exhibiting an EC50 of 3.4 μM for cellular target engagement within DHX9. It is primarily utilized in cancer research [1].Formula:C18H16N2O3S2Color and Shape:SolidMolecular weight:372.46Metribuzin
CAS:Metribuzin is a selective herbicide used on crops like soybeans and potatoes. It inhibits photosynthesis and is a persistent groundwater contaminant.
Formula:C8H14N4OSPurity:99.07%Color and Shape:Colorless Crytals Metribuzin Is A Colorless Crystalline Solid Used As An Herbicide (Niosh 2016)Molecular weight:214.29Tilatamig samrotecan
Tilatamig samrotecan (AZD9592) is an antibody-drug conjugate (ADC) designed to deliver a topoisomerase I inhibitor (TOP1i). It targets epidermal growth factor receptor (EGFR) and c-MET and demonstrates antitumor activity. The compound induces DNA double-strand breaks, elevates pRAD50 and γH2AX expression, and inhibits the growth of non-small cell lung cancer.Color and Shape:Odour SolidE-982
CAS:E-982 is derived from the reference compound.Formula:C25H31NO6SPurity:98%Color and Shape:SolidMolecular weight:473.582'-Azido-2'-deoxyuridine
CAS:2'-Azido-2'-deoxyuridine (N3dUrd) is a ribonucleotide reductase inhibitor with anti-cancer activity.Formula:C9H11N5O5Purity:98%Color and Shape:SolidMolecular weight:269.21RI(dl)-2 TFA
CAS:RI(dl)-2 TFA inhibits RAD51 D-loop at 11.1 μM and HR in human cells at 3.0 μM.Formula:C19H17N3Color and Shape:SolidMolecular weight:287.36Halofuginone
CAS:Halofuginone (RU-19110) inhibits prolyl-tRNA synthetase (Ki=18.3 nM), down-regulates Smad3, and blocks TGF-β at 10 ng/ml.Formula:C16H17BrClN3O3Purity:99.53%Color and Shape:Off-White SolidMolecular weight:414.68Ref: TM-T6856
1mg34.00€5mg82.00€10mg116.00€25mg227.00€50mg344.00€100mg517.00€500mg1,134.00€1mL*10mM (DMSO)92.00€3,4-Dihydroxybenzylamine hydrobromide
CAS:3,4-Dihydroxybenzylamine hydrobromide inhibits DNA polymerase and melanoma growth, varying with tyrosinase activity.Formula:C7H10BrNO2Purity:98.49%Color and Shape:Light Beige Crystalline PowderMolecular weight:220.06E3330
CAS:E3330 is a potent and selective APE1(Ref-1) inhibitor, which suppressed NF-kappa B DNA-binding activity.Formula:C21H30O6Purity:99.52%Color and Shape:SolidMolecular weight:378.46BAY-707
CAS:BAY-707: tolerable in mice, no anticancer efficacy; potent, selective MTH1 inhibitor, IC50 = 2.3 nM; good PK profile.Formula:C15H20N4O2Purity:98%Color and Shape:SolidMolecular weight:288.342-Fluoroadenine
CAS:2-Fluoroadenine (NSC-27364) has toxicity in nonproliferating and proliferating tumor cells. 2-Fluoroadenine can be used for anticancer studies.
Formula:C5H4FN5Purity:98.84% - 99.62%Color and Shape:White To Light Yellow Crystal PowderMolecular weight:153.12CBL 0100 free base
CAS:CBL0100 is an inhibitor of viral transcriptional elongation, blocking both HIV-1 replication and reactivation.Formula:C24H26N2O2Purity:98.18% - 98.86%Color and Shape:SolidMolecular weight:374.48Halofuginone hydrobromide
CAS:Halofuginone specifically inhibits collagen type I and MMP-2 gene expression, which may result in the suppression of angiogenesis and tumor cell growth.Formula:C16H17BrClN3O3·HBrPurity:97.01% - 99.73%Color and Shape:SolidMolecular weight:495.59Ref: TM-T3524
1mg34.00€2mg49.00€5mg74.00€10mg106.00€25mg207.00€50mg310.00€100mg469.00€500mg897.00€1mL*10mM (DMSO)84.00€CTP Synthetase-IN-1
CAS:CTP Synthetase-IN-1 is a cytidine 5'-triphosphate synthetase (CTPS) inhibitor with antitumor activity for the study of arthritis and rheumatoid arthritis.Formula:C20H19F3N6O3S2Purity:98.11% - 99.18%Color and Shape:SolidMolecular weight:512.53Ref: TM-T72505
1mg65.00€5mg141.00€10mg230.00€25mg477.00€50mg803.00€100mg1,378.00€1mL*10mM (DMSO)158.00€2-Keto-D-galactose
CAS:2-Keto-D-galactose inhibits DNA synthesis and inhibits the proliferation of in vitro grown Ehrlich ascites tumor cells.Formula:C6H10O6Purity:98%Color and Shape:SolidMolecular weight:178.14Antitumor agent-84
Antitumor agent-84 stabilizes G-quadruplex DNA, exhibits potent anti-tumor effects.Formula:C24H31N7Color and Shape:SolidMolecular weight:417.55Synucleozid
CAS:Synucleozid is a potent the SNCA mRNA inhibitor that encodes α-synuclein protein (IC50=1.5 μM), has the potential for the investigation of Parkinson’s disease.Formula:C22H20N6Purity:98%Color and Shape:SolidMolecular weight:368.43Braco-19 trihydrochloride
CAS:BRACO19 3HCl inhibits telomerase, blocking its capping function, and prevents HAdV viral replication.Formula:C35H46Cl3N7O2Purity:98.74%Color and Shape:SolidMolecular weight:703.14HBV-IN-22
CAS:HBV-IN-22 (Compound LC5f) is an HBV DNA replication inhibitor that acts on both wild-type HBV (IC50: 0.71 μM) and drug-resistant HBV (IC50: 0.84 μM).Formula:C26H29N3O2S2Color and Shape:SolidMolecular weight:479.66BPIC
CAS:BPIC is an agent of anti-tumor that acts by inhibiting inflammation and scavenging free radicals.Formula:C27H20N2O5Color and Shape:SolidMolecular weight:452.46NSC666715
CAS:NSC666715 is the strand-displacement activity of DNA polymerase inhibitor.Formula:C15H13Cl2N5O2S2Purity:98%Color and Shape:SolidMolecular weight:430.33RHI002-Me
CAS:RHI002-Me is a methylated derivative of RHI002, a selective inhibitor of human RNaseH2.Formula:C18H19N3O2S2Purity:98%Color and Shape:SolidMolecular weight:373.49Apricitabine
CAS:Apricitabine (SPD754) is a highly selective and orally active HIV-1 reverse transcriptase inhibitor (Ki=0.08 μM), the (-) enantiomer of 2′-deoxy-3′-oxy-4′-Formula:C8H11N3O3SPurity:99.45%Color and Shape:SolidMolecular weight:229.26Ref: TM-T14313
1mg283.00€5mg507.00€10mg628.00€25mg962.00€50mg1,601.00€100mg2,682.00€1mL*10mM (DMSO)592.00€BMVC
CAS:BMVC is a potent G-quadruplex (G4) stabilizer and a selective telomerase inhibitor (IC50: ~0.2 μM) with anticancer activities.Formula:C28H25I2N3Color and Shape:SolidMolecular weight:657.33Bofumustine
CAS:Bofumustine is a chloroethyl nitrosourea with anti tumor properties.Formula:C18H21ClN4O9Color and Shape:SolidMolecular weight:472.83Nitracrine
CAS:Nitracrine: a 1-nitroacridine, hypoxia-selective, anti-tumor agent; inhibits RNA synthesis, binds DNA reversibly and forms covalent adducts.Formula:C18H20N4O2Purity:98%Color and Shape:SolidMolecular weight:324.38DDD100097
CAS:DDD100097 is a N-myristoyltransferase inhibitor with potential inhibitory effects on Trypanosoma brucei, which can be used to study neurological disorders.Formula:C22H30Cl2F2N4O2SPurity:98.89%Color and Shape:SolidMolecular weight:523.47D-Xylofuranose, 1,2,3,5-tetraacetate
CAS:1,2,3,5-Tetra-O-acetyl-D-xylofuranose is a starting material for the synthesis of nucleosides.Formula:C13H18O9Color and Shape:SolidMolecular weight:318.28BMVC2
CAS:BMVC2 (o-BMVC), a carbazole derivative of BMVC, is a G-quadruplex (G4) stabilizer.Formula:C28H25I2N3Color and Shape:SolidMolecular weight:657.33Enocitabine
CAS:Enocitabine is a nucleoside analog.Formula:C31H55N3O6Purity:97.22%Color and Shape:SolidMolecular weight:565.78BMH-23
CAS:BMH-23 is an RNA polymerase I inhibitor that acts by causing nucleolar stress and showing potent anticancer activity across many tumor types.Formula:C15H15N3Purity:98%Color and Shape:SolidMolecular weight:237.3BMH-22
CAS:BMH-22 is an RNA polymerase I inhibitor that acts by causing nucleolar stress and showing potent anticancer activity across many tumor types.Formula:C16H17N3Color and Shape:SolidMolecular weight:251.33Triaziquone
CAS:Triaziquone is an alkylating agent that can react with DNA to form intrastrand crosslinks.Formula:C12H13N3O2Color and Shape:SolidMolecular weight:231.25ST7612AA1
CAS:ST7612AA1: potent, oral HDAC inhibitor; reactivates HIV-1 latency; shows antitumor effects; may study malaria.Formula:C20H27N3O4SPurity:99.71%Color and Shape:SolidMolecular weight:405.51Direct Black 38 free acid
CAS:Ferristatin II (Direct Black 38 free acid) is a polysulphonated dye and promotes the degradation of transferrin receptor-1 in vitro and in vivo.Formula:C34H27N9O7S2Purity:98%Color and Shape:SolidMolecular weight:737.77S-(N-PhenethylthiocarbaMoyl)-L-cysteine
CAS:PEITC-Cys: anticarcinogenic, antileukemic, inhibits DNA synthesis in HL60, P450 inhibitor.Formula:C12H16N2O2S2Color and Shape:SolidMolecular weight:284.48-Azido-ADP disodium
CAS:8-Azido-ADP (disodium) is a covalent inhibitor of ADP/ATP exchange in mitochondria, causing irreversible inhibition in light.Formula:C10H13N8NaO10P2Color and Shape:SolidMolecular weight:490.197MTH1-IN-2
CAS:MTH1-IN-2 is an inhibitor of MutT homolog 1 (MTH1), with anti-tumor activity.Formula:C24H27N3O5SPurity:98%Color and Shape:SolidMolecular weight:469.55SPC-839
CAS:SPC-839 is an IKK-2 Inhibitor with oral activity.Formula:C18H14N4O3SColor and Shape:SolidMolecular weight:366.39360A iodide
CAS:360A iodide is a selective stabilizer of G-quadruplex and inhibits telomerase activity (IC50: 300 nM in TRAP-G4 assay).Formula:C27H23I2N5O2Purity:98%Color and Shape:SolidMolecular weight:703.31Phen-DC3
CAS:Phen-DC3 is a G-quadruplex (G4) specific ligand which can inhibit FANCJ and DinG helicases (IC50s of 65±6 and 50±10 nM, respectively).Formula:C34H26N6O2Purity:98%Color and Shape:SolidMolecular weight:550.61
