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PI3K/Akt/mTOR Signaling

PI3K/Akt/mTOR Signaling

PI3K/Akt/mTOR signaling inhibitors are compounds that target the phosphoinositide 3-kinase (PI3K), Akt kinase, and mammalian target of rapamycin (mTOR) pathways. These pathways are critical regulators of cell growth, survival, metabolism, and autophagy, making them key targets in cancer research and metabolic disorders. Inhibiting these pathways can help to control tumor growth and proliferation, offering potential therapeutic strategies for various cancers and other diseases characterized by dysregulated cell signaling. At CymitQuimica, we offer a comprehensive selection of high-quality PI3K/Akt/mTOR inhibitors to support your research in oncology, cellular signaling, and metabolic diseases.

Subcategories of "PI3K/Akt/mTOR Signaling"

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Found 1037 products of "PI3K/Akt/mTOR Signaling"

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  • SRX3207
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    SRX3207

    CAS:
    <p>SRX3207 is an inhibitor of Syk and PI3K and relieves tumor immunosuppression.</p>
    Formula:C29H29N7O3S
    Purity:99.85%
    Color and Shape:Solid
    Molecular weight:555.65

    Ref: TM-T22430

  • GSK-3β inhibitor 11
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    GSK-3β inhibitor 11

    CAS:
    <p>GSK-3β inhibitor 11 (compound 21) is a potent inhibitor of glycogen synthase kinase-3β (GSK-3β) with an inhibitory concentration (IC50) of 10.02 μM.</p>
    Formula:C20H15N3O4S
    Purity:97.33%
    Color and Shape:Solid
    Molecular weight:393.42

    Ref: TM-T61809

  • BIP-135
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    BIP-135

    CAS:
    <p>BIP-135 is a potent and selective ATP-competitive GSK-3 inhibitor.</p>
    Formula:C21H13BrN2O3
    Purity:99.93%
    Color and Shape:Solid
    Molecular weight:421.24

    Ref: TM-T14613

  • Epitinib succinate
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    Epitinib succinate

    CAS:
    <p>Epitinib succinate (HMPL-813 succinate) is an orally active and brain penetration EGFR tyrosine kinase inhibitor and can be used in studies about cancer.</p>
    Formula:C28H32N6O6
    Purity:98.02% - 99.79%
    Color and Shape:Solid
    Molecular weight:548.59

    Ref: TM-T35914

  • EMI1
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    EMI1

    CAS:
    <p>EMI1 targets mutated EGFR in drug-resistant NSCLC research.</p>
    Formula:C20H18N2O3
    Purity:99.96%
    Color and Shape:Solid
    Molecular weight:334.37

    Ref: TM-T61016

  • Falnidamol
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    Falnidamol

    CAS:
    <p>Falnidamol (BIBX 1382), an oral selective EGFR inhibitor, IC50 3 nM, weak on ErbB2 and others, anti-cancer pyrimido-pyrimidine.</p>
    Formula:C18H19ClFN7
    Purity:98.816%
    Color and Shape:Solid
    Molecular weight:387.84

    Ref: TM-TQ0271

  • EHT 1610
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    EHT 1610

    CAS:
    <p>EHT 1610 (EHT 5372) is a potent inhibitor of DYRK, with an IC50 of 0.36 nM and 0.59 nM for DYRK1A and DYRK1B, respectively.</p>
    Formula:C18H14FN5O2S
    Purity:98.59%
    Color and Shape:Solid
    Molecular weight:383.4

    Ref: TM-T15204

  • GSK-3 Inhibitor XIII
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    GSK-3 Inhibitor XIII

    CAS:
    <p>GSK-3 InhibitorXIII, an ATP-competitive GSK-3 inhibitor (Ki: 24 nM), can be used to study diabetes and obesity.</p>
    Formula:C18H15N5
    Purity:99.85% - 99.86%
    Color and Shape:Solid
    Molecular weight:301.35

    Ref: TM-T78578

  • Sunvozertinib
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    Sunvozertinib

    CAS:
    <p>Sunvozertinib (DZD9008) is a potent ErbBs and BTK inhibitor, with inhibitory effects on EGFR, Her2.Cost-effective and quality-assured.</p>
    Formula:C29H35ClFN7O3
    Purity:98.11% - 99.63%
    Color and Shape:Solid
    Molecular weight:584.08

    Ref: TM-T64124

  • EGFR-IN-99
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    EGFR-IN-99

    CAS:
    <p>EGFR-IN-99 (JBJ-03-142-02) is an EGFR and HER2 Exon 20 insertion mutation inhibitor for the study of non-small cell lung cancer (NSCLC).</p>
    Formula:C25H22FN7O3
    Purity:97.75%
    Color and Shape:Solid
    Molecular weight:487.49

    Ref: TM-T35901

  • Cloperastine fendizoate
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    Cloperastine fendizoate

    CAS:
    <p>Cloperastine fendizoate (Hustazol) inhibits the hERG K+ currents in a concentration-dependent manner (IC50: 27 nM).</p>
    Formula:C40H38ClNO5
    Purity:99.97%
    Color and Shape:Solid
    Molecular weight:648.19

    Ref: TM-T13619

  • A-935142
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    A-935142

    CAS:
    <p>A-935142 enhances hERG (Kv 11.1) channels, slows inactivation, promotes activation, and shortens repolarization.</p>
    Formula:C18H19F3N2O2
    Purity:98.97% - 99.91%
    Color and Shape:Solid
    Molecular weight:352.35

    Ref: TM-T14077

  • GS-9901
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    GS-9901

    CAS:
    <p>GS-9901 is a selective, orally active and potent PI3Kδ inhibitor (IC50: 1 nM) for the study of non-Hodgkin's lymphoma and chronic lymphocytic leukemia.</p>
    Formula:C22H17ClFN9O
    Purity:98.60% - 99.92%
    Color and Shape:Solid
    Molecular weight:477.88

    Ref: TM-T15420

  • PD 174265
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    PD 174265

    CAS:
    <p>PD 174265 is an effective, selective and reversible inhibitor of epidermal growth factor receptor (EGFR) with an IC50 of 0.45 nM.</p>
    Formula:C17H15BrN4O
    Purity:99.51%
    Color and Shape:Solid
    Molecular weight:371.23

    Ref: TM-T28339

  • Tyrphostin A25
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    Tyrphostin A25

    CAS:
    <p>Tyrphostin A25 (Tyrphostin AG 82) is a specific EGFR tyrosine kinase inhibitor and GPR35 agonist with an IC50 value of 0.94 μM for GPR35 and an EC50 value of 5.</p>
    Formula:C10H6N2O3
    Purity:98.76%
    Color and Shape:Yellow Green Powder /Off-White Solid
    Molecular weight:202.17

    Ref: TM-T21622

  • AZ044
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    AZ044

    CAS:
    <p>AZ044 is a potent, selective inhibitor of type III phosphatidylinositol-4-kinase alpha-subtype (PI4KIIIalpha).</p>
    Formula:C24H27N3O3S
    Purity:99.5%
    Color and Shape:Solid
    Molecular weight:437.55

    Ref: TM-T26698

  • DIF-3
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    DIF-3

    CAS:
    <p>DIF-3 activates GSK-3β, degrades cyclin D1/c-Myc, and inhibits Wnt/β-catenin in DLD-1 cells, curbing HeLa cell proliferation.</p>
    Formula:C13H17ClO4
    Purity:99.57%
    Color and Shape:Solid
    Molecular weight:272.72

    Ref: TM-T60485

  • SKLB 1028
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    SKLB 1028

    CAS:
    <p>SKLB 1028, an oral EGFR/FLT3/Abl inhibitor, excels in AML and CML with Abl mutations.</p>
    Formula:C24H29N9
    Purity:99.90% - >99.99%
    Color and Shape:Solid
    Molecular weight:443.55

    Ref: TM-T34656

  • ARN25068
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    ARN25068

    CAS:
    <p>ARN25068 inhibits GSK-3β, FYN, DYRK1A kinases; acts in sub-micromolar range; combats tau hyperphosphorylation.</p>
    Formula:C19H18N6S
    Purity:99.75%
    Color and Shape:Solid
    Molecular weight:362.45

    Ref: TM-T61360

  • PQR514
    Targetmol
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    PQR514

    CAS:
    <p>PQR514: more potent pan-PI3K inhibitor than predecessor PQR309, exhibits strong anticancer activity in vitro and in OVCAR-3 model.</p>
    Formula:C16H20F2N8O2
    Purity:98.77% - 99.19%
    Color and Shape:Solid
    Molecular weight:394.38

    Ref: TM-T70058