CymitQuimica logo
PI3K/Akt/mTOR Signaling

PI3K/Akt/mTOR Signaling

PI3K/Akt/mTOR signaling inhibitors are compounds that target the phosphoinositide 3-kinase (PI3K), Akt kinase, and mammalian target of rapamycin (mTOR) pathways. These pathways are critical regulators of cell growth, survival, metabolism, and autophagy, making them key targets in cancer research and metabolic disorders. Inhibiting these pathways can help to control tumor growth and proliferation, offering potential therapeutic strategies for various cancers and other diseases characterized by dysregulated cell signaling. At CymitQuimica, we offer a comprehensive selection of high-quality PI3K/Akt/mTOR inhibitors to support your research in oncology, cellular signaling, and metabolic diseases.

Subcategories of "PI3K/Akt/mTOR Signaling"

Show 2 more subcategories

Found 1032 products of "PI3K/Akt/mTOR Signaling"

Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
products per page.
  • EGFR-IN-69
    Targetmol
    + Info

    EGFR-IN-69

    CAS:
    EGFR-IN-69: Potent EGFR inhibitor for NSCLC research; IC50: 4.3-25.6 nM against various EGFR mutations.
    Formula:C31H37Cl2N7O3S
    Color and Shape:Solid
    Molecular weight:658.64

    Ref: TM-T73153

  • EGFR-IN-68
    Targetmol
    + Info

    EGFR-IN-68

    CAS:
    EGFR-IN-68, an EGFR inhibitor, has an IC50 of 0.33 μM and shows significant anticancer effects.
    Formula:C24H22N2O
    Color and Shape:Solid
    Molecular weight:354.44

    Ref: TM-T61267

  • BRD1652
    Targetmol
    + Info

    BRD1652

    CAS:
    BRD1652 is a highly selective and potent GSK3 inhibitor.
    Formula:C20H20F3N3O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:375.39

    Ref: TM-T26896

  • Limertinib
    Targetmol
    + Info

    Limertinib

    CAS:
    <p>Limertinib (ASK120067) is a EGFR tyrosine kinase inhibitor targeting EGFR T790M, applicable for the study of non-small cell lung cancer.</p>
    Formula:C29H32ClN7O2
    Purity:97.44%
    Color and Shape:Solid
    Molecular weight:546.06

    Ref: TM-T35897

  • EGFR-IN-54
    Targetmol
    + Info

    EGFR-IN-54

    CAS:
    EGFR-IN-54 (Compound 3c) is a potent inhibitor of EGFR (IC50: 1.623 μM) and is toxic to cancer cells.
    Formula:C17H14N4O4S3
    Color and Shape:Solid
    Molecular weight:434.51

    Ref: TM-T62457

  • FT-1518
    Targetmol
    + Info

    FT-1518

    CAS:
    FT-1518 is an orally available, selective and potent mTORC1 and mTORC2 inhibitor with anticancer and antitumor activity for cancer research.
    Formula:C20H26N8O
    Purity:98.34% - 98.80%
    Color and Shape:Solid
    Molecular weight:394.47

    Ref: TM-T11328

  • EGFR-IN-25
    Targetmol
    + Info

    EGFR-IN-25

    CAS:
    EGFR-IN-25, an efficacious EGFR inhibitor, demonstrates IC50 values of 9 nM for BaF3 cells (EGFR DEL19/T790M/C797S) and 60 nM for A431 cells (WT), respectively.
    Formula:C34H43N9O2
    Color and Shape:Solid
    Molecular weight:609.76

    Ref: TM-T73101

  • JBJ-09-063 hydrochloride
    Targetmol
    + Info

    JBJ-09-063 hydrochloride

    JBJ-09-063 hydrochloride: targeted EGFR inhibitor, effective for various mutations and TKI-resistant lung cancer models.
    Formula:C31H30ClFN4O3S
    Color and Shape:Solid
    Molecular weight:593.11

    Ref: TM-T72237

  • FD2056
    Targetmol
    + Info

    FD2056

    CAS:
    <p>FD2056 is a potent, orally active PI3K inhibitor, with IC50 values of 0.30, 0.80, 1.10, and 0.42 nM against PI3Kα, PI3Kβ, PI3Kγ, and PI3Kδ, respectively.</p>
    Formula:C23H17ClN6O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:476.94

    Ref: TM-T79370

  • EGFR-IN-89
    Targetmol
    + Info

    EGFR-IN-89

    CAS:
    <p>EGFR-IN-89 (compound 13k) is a fourth-generation inhibitor selectively targeting EGFR mutations, exhibiting potent activity with an IC50 of 10.1 nM against</p>
    Formula:C26H31FN8O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:538.64

    Ref: TM-T79775

  • Tyrphostin AG 112
    Targetmol
    + Info

    Tyrphostin AG 112

    CAS:
    Tyrphostin AG 112 is an inhibitor of EGFR phosphorylation.
    Formula:C13H8N4O
    Purity:99.14%
    Color and Shape:Solid
    Molecular weight:236.23

    Ref: TM-T8534

  • MTX-531
    Targetmol
    + Info

    MTX-531

    CAS:
    MTX-531 is a selective inhibitor of EGFR and PI3K with IC50 of 14.7   nM and 1.1-233  nM (PI3Kα, PI3Kβ...), respectively. It also acts as a weak agonist of PPARγ, with an EC50 of 3.4 μM in 293H cells.
    Formula:C22H20ClN5O2S
    Color and Shape:Soild
    Molecular weight:453.94

    Ref: TM-T88436

  • NVP-CLR457
    Targetmol
    + Info

    NVP-CLR457

    CAS:
    NVP-CLR457 is an oral pan-class I PI3K inhibitor with dose-dependent antitumor activity.
    Formula:C18H20F3N7O4
    Color and Shape:Solid
    Molecular weight:455.39

    Ref: TM-T62816

  • EGFR/HER2-IN-2
    Targetmol
    + Info

    EGFR/HER2-IN-2

    CAS:
    EGFR/HER2-IN-2 (Compound ZINC35560729) is a dual EGFR and HER2 inhibitor that acts on both EGFR (IC50: 5.02 μM) and HER2 (IC50: 0.83 μM).
    Formula:C26H23N5O3
    Color and Shape:Solid
    Molecular weight:453.49

    Ref: TM-T62776

  • Larotinib
    Targetmol
    + Info

    Larotinib

    CAS:
    <p>Larotinib is an orally active, potent, and broad-spectrum tyrosine kinase inhibitor (TKI) with an IC50 of 0.6 nM for EGFR.</p>
    Formula:C24H26ClFN4O4
    Purity:98.45%
    Color and Shape:Solid
    Molecular weight:488.94

    Ref: TM-T73334

  • Rezivertinib
    Targetmol
    + Info

    Rezivertinib

    CAS:
    <p>Rezivertinib (BPI-7711) is an EGFR inhibitor with antitumor activity and can be used to study central nervous system diseases.</p>
    Formula:C27H30N6O3
    Purity:99.26% - 99.89%
    Color and Shape:Solid
    Molecular weight:486.57

    Ref: TM-T36644

  • A-935142
    Targetmol
    + Info

    A-935142

    CAS:
    A-935142 enhances hERG (Kv 11.1) channels, slows inactivation, promotes activation, and shortens repolarization.
    Formula:C18H19F3N2O2
    Purity:98.97% - 99.91%
    Color and Shape:Solid
    Molecular weight:352.35

    Ref: TM-T14077

  • Falnidamol
    Targetmol
    + Info

    Falnidamol

    CAS:
    <p>Falnidamol (BIBX 1382), an oral selective EGFR inhibitor, IC50 3 nM, weak on ErbB2 and others, anti-cancer pyrimido-pyrimidine.</p>
    Formula:C18H19ClFN7
    Purity:98.816%
    Color and Shape:Solid
    Molecular weight:387.84

    Ref: TM-TQ0271

  • RS1-PDK1 inhibitor
    Targetmol
    + Info

    RS1-PDK1 inhibitor

    CAS:
    <p>RS1-PDK1 inhibitor (RS 1) is a selective inhibitor of the protein kinase PDK1 that can be used to treat and prevent disease or disorders.</p>
    Formula:C15H9ClN2O2S3
    Purity:98.12%
    Color and Shape:Solid
    Molecular weight:380.89

    Ref: TM-T24741

  • BIP-135
    Targetmol
    + Info

    BIP-135

    CAS:
    <p>BIP-135 is a potent and selective ATP-competitive GSK-3 inhibitor.</p>
    Formula:C21H13BrN2O3
    Purity:99.93%
    Color and Shape:Solid
    Molecular weight:421.24

    Ref: TM-T14613