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gsk-3

gsk-3

GSK-3 inhibitors are compounds that target Glycogen Synthase Kinase 3 (GSK-3), an enzyme involved in numerous cellular processes, including glycogen metabolism, gene transcription, and cell proliferation. GSK-3 is implicated in various diseases, such as diabetes, neurodegenerative disorders, and cancer. Inhibitors of GSK-3 are important tools for exploring these pathways and developing potential therapies. At CymitQuimica, we provide GSK-3 inhibitors to support your research in metabolic diseases, neurobiology, and oncology.

Found 112 products of "gsk-3"

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  • TDZD-8
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    TDZD-8

    CAS:
    <p>TDZD-8 (NP 01139) is an inhibitor of GSK-3β, with an IC50 of 2 μM; minimal inhibitory effect observed on CDK1, casein kinase II, PKA and PKC.</p>
    Formula:C10H10N2O2S
    Purity:97.13% - 99.61%
    Color and Shape:White Solid
    Molecular weight:222.26

    Ref: TM-T6187

  • Bisindolylmaleimide I
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    Bisindolylmaleimide I

    CAS:
    <p>Bisindolylmaleimide I (GF109203X) is a potent and highly selective protein kinase C (PKC) inhibitor with a Ki of 14 nM.</p>
    Formula:C25H24N4O2
    Purity:98.19% - 98.75%
    Color and Shape:Orange Solid
    Molecular weight:412.48

    Ref: TM-T6513

  • SB 216763
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    SB 216763

    CAS:
    <p>SB 216763 (SB216763) is an effective and specific GSK-3α/β inhibitor (IC50: 34.3 nM).</p>
    Formula:C19H12Cl2N2O2
    Purity:98.9% - 99.13%
    Color and Shape:Solid
    Molecular weight:371.22

    Ref: TM-T3077

  • CP21R7
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    CP21R7

    CAS:
    <p>CP21 is a specific GSK3β inhibitor, used to activate stem cells for differentiation, often paired with BMP4 for mesodermal fate.</p>
    Formula:C19H15N3O2
    Purity:96.14% - 99.16%
    Color and Shape:Solid
    Molecular weight:317.34

    Ref: TM-T3684

  • TWS119
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    TWS119

    CAS:
    <p>TWS119 is a GSK-3β inhibitor; capable of inducing neuronal differentiation</p>
    Formula:C18H14N4O2
    Purity:98.14% - 99.63%
    Color and Shape:Solid
    Molecular weight:318.33

    Ref: TM-T2166

  • Indirubin-3'-monoxime
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    Indirubin-3'-monoxime

    CAS:
    <p>Indirubin-3'-monoxime (Indirubin-3'-oxime) is a potent inhibitor of GSK3β (IC50: 22 nM) and also inhibits CDKs ( (IC50s: 100/180/250 nM for Cdk5/p35, Cdk1/</p>
    Formula:C16H11N3O2
    Purity:99.55%
    Color and Shape:Dark Red Solid
    Molecular weight:277.28

    Ref: TM-T5200

  • GSK 3 Inhibitor IX
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    GSK 3 Inhibitor IX

    CAS:
    <p>GSK 3 Inhibitor IX (6-BIO) is a selective reversible, ATP-competitive inhibitor of GSK-3α/β and CDK1-cyclinB complex.</p>
    Formula:C16H10BrN3O2
    Purity:98% - 99.72%
    Color and Shape:Solid
    Molecular weight:356.17

    Ref: TM-T1917

  • KY19382
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    KY19382

    CAS:
    <p>KY19382, a dual CXXC5-DVL and GSK3β inhibitor (IC50s: 19/10 nM), boosts Wnt/β-catenin signaling and may help in metabolic disease research.</p>
    Formula:C17H11Cl2N3O2
    Purity:98.06%
    Color and Shape:Solid
    Molecular weight:360.19

    Ref: TM-T9025

  • IM-12
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    IM-12

    CAS:
    <p>IM-12, an effective GSK-3β inhibitor(IC50=53 nM), regulates Wnt signalling.</p>
    Formula:C22H20FN3O2
    Purity:99.42% - >99.99%
    Color and Shape:Solid
    Molecular weight:377.41

    Ref: TM-T2261

  • Tideglusib
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    Tideglusib

    CAS:
    <p>Tideglusib (NP031112), a non-ATP competitive inhibitor of glycogen synthase kinase 3 (GSK-3), is with anti-inflammatory and neuroprotective activities.</p>
    Formula:C19H14N2O2S
    Purity:98.40% - 99.35%
    Color and Shape:Solid
    Molecular weight:334.39

    Ref: TM-T3067

  • LY2090314
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    LY2090314

    CAS:
    <p>LY2090314, a potent GSK-3α/β blocker (IC50: 1.5/0.9 nM), could boost platinum chemo. Tested in leukemia and advanced cancers.</p>
    Formula:C28H25FN6O3
    Purity:99.21% - 99.91%
    Color and Shape:Solid
    Molecular weight:512.53

    Ref: TM-T1755

  • GS87
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    GS87

    CAS:
    <p>GS87 is a highly specific inhibitor of GSK3 (glycogen synthase kinase 3) that induces extensive differentiation of AML cells.</p>
    Formula:C16H11N5O2S
    Purity:98.86%
    Color and Shape:Solid
    Molecular weight:337.36

    Ref: TM-T8605

  • AZD1080
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    AZD1080

    CAS:
    <p>AZD1080 is a selective, orally active, brain permeable GSK3 inhibitor.</p>
    Formula:C19H18N4O2
    Purity:97.72% - 99.75%
    Color and Shape:Solid
    Molecular weight:334.37

    Ref: TM-T1741

  • BIO-acetoxime
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    BIO-acetoxime

    CAS:
    <p>BIO-acetoxime (GSK-3 Inhibitor X) is a potent dual GSK3α/β inhibitor with IC50 of 10 nM, &gt;240-fold selectivity over CDK5/p25, CDK2/cyclin A and CDK1/cyclin B.</p>
    Formula:C18H12BrN3O3
    Purity:97.15%
    Color and Shape:Solid
    Molecular weight:398.21

    Ref: TM-T6787

  • Bikinin
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    Bikinin

    CAS:
    <p>Bikinin (Abrasin), a potent inhibitor of plant GSK-3/Shaggy-like kinase, activates BR signaling downstream of the BR receptor.</p>
    Formula:C9H9BrN2O3
    Purity:99.86% - >99.99%
    Color and Shape:Solid
    Molecular weight:273.08

    Ref: TM-T1965

  • GSK-3β inhibitor 10
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    GSK-3β inhibitor 10

    CAS:
    <p>GSK-3β inhibitor 10 has skin-whitening, anti-oxidizing and PPAR activities.</p>
    Formula:C12H12N2O3S
    Purity:98.06%
    Color and Shape:Solid
    Molecular weight:264.3

    Ref: TM-T9725

  • RGB-286638 free base
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    RGB-286638 free base

    CAS:
    <p>RGB-286638 free base inhibits CDKs (1-5 nM), weaker on CDK7/6.</p>
    Formula:C29H35N7O4
    Purity:98% - 99.91%
    Color and Shape:Solid
    Molecular weight:545.63

    Ref: TM-T2378

  • GNF4877
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    GNF4877

    CAS:
    <p>GNF4877 inhibits DYRK1A/GSK3β (IC50: 6/16 nM), blocks NFATc export, and boosts β-cell growth.</p>
    Formula:C25H27FN6O4
    Purity:98.68% - 99.40%
    Color and Shape:Solid
    Molecular weight:494.52

    Ref: TM-T11447

  • (E/Z)-GSK-3β inhibitor 1
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    (E/Z)-GSK-3β inhibitor 1

    CAS:
    <p>(E/Z)-GSK-3β inhibitor 1 is a glycogen synthase kinase 3β (GSK-3β) inhibitor and demonstrates high antidiabetic efficacy.</p>
    Formula:C14H10N2O
    Purity:98.60%
    Color and Shape:Solid
    Molecular weight:222.24

    Ref: TM-T9178

  • 7BIO
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    7BIO

    CAS:
    <p>7BIO triggers nonapoptotic death, blocks FLT3, DYRK1A/2, Aurora B/C kinases.</p>
    Formula:C16H10BrN3O2
    Purity:99.67%
    Color and Shape:Solid
    Molecular weight:356.17

    Ref: TM-T22012