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gsk-3

gsk-3

GSK-3 inhibitors are compounds that target Glycogen Synthase Kinase 3 (GSK-3), an enzyme involved in numerous cellular processes, including glycogen metabolism, gene transcription, and cell proliferation. GSK-3 is implicated in various diseases, such as diabetes, neurodegenerative disorders, and cancer. Inhibitors of GSK-3 are important tools for exploring these pathways and developing potential therapies. At CymitQuimica, we provide GSK-3 inhibitors to support your research in metabolic diseases, neurobiology, and oncology.

Found 112 products of "gsk-3"

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  • 5-Iodo-indirubin-3'-monoxime
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    5-Iodo-indirubin-3'-monoxime

    CAS:
    <p>5-Iodo-indirubin-3'-monoxime is a potent GSK-3β, CDK5/P25 and CDK1/cyclin B inhibitor, competing with ATP for binding to the catalytic site of the kinase (IC50s</p>
    Formula:C16H10IN3O2
    Color and Shape:Solid
    Molecular weight:403.17

    Ref: TM-T10172

  • GSK-3 inhibitor 1
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    GSK-3 inhibitor 1

    CAS:
    <p>GSK-3 inhibitor 1 is a GSK-3 inhibitor.</p>
    Formula:C22H17ClFN5O2
    Purity:98.42%
    Color and Shape:Solid
    Molecular weight:437.85

    Ref: TM-T11468

  • GSK3β-IN-1
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    GSK3β-IN-1

    CAS:
    <p>GSK3β-IN-1 (compound 1) is an inhibitor of glycogen synthase kinase-3β (GSK-3β) with an IC50 value of 65 nM, and it is utilized in Alzheimer's disease research.</p>
    Formula:C17H13FN2O4S
    Color and Shape:Solid
    Molecular weight:360.36

    Ref: TM-T204474

  • GSK3β-IN-2
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    GSK3β-IN-2

    CAS:
    <p>GSK3β-IN-2 (Compound S01) is an inhibitor of GSK3β with an IC50 of 0.35 nM. It activates the Wnt/β-catenin signaling pathway, promoting neurogenesis and neurite outgrowth. GSK3β-IN-2 reduces tau protein phosphorylation induced by Aβ at the Ser396 site, thereby decreasing neurofibrillary tangles. Furthermore, GSK3β-IN-2 improves Alzheimer's disease symptoms in a zebrafish model.</p>
    Formula:C25H18N4O
    Color and Shape:Solid
    Molecular weight:390.437

    Ref: TM-T205461

  • GSK-3β inhibitor 26
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    GSK-3β inhibitor 26

    CAS:
    <p>GSK-3β inhibitor26 (Compound D14) is a GSK-3β inhibitor with an IC50 of 18.23 μM. This compound is applicable in research related to cancer, inflammation, and neurodegenerative diseases.</p>
    Formula:C15H11N3O3
    Color and Shape:Solid
    Molecular weight:281.266

    Ref: TM-T205441

  • 5-Bromo-3-indoxylacetate
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    5-Bromo-3-indoxylacetate

    CAS:
    <p>5-Bromo-3-indoxylacetate acts as an inhibitor of GSK-3, with a pIC50 value of 3.39.</p>
    Formula:C10H8BrNO2
    Color and Shape:Solid
    Molecular weight:254.08

    Ref: TM-T205502

  • GSK-3β inhibitor 20
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    GSK-3β inhibitor 20

    CAS:
    <p>GSK-3β inhibitor20 (compound 3A) is an effective inhibitor of GSK-3β, exhibiting an IC50 value of 74.4 nM.</p>
    Formula:C22H21N5O2S
    Color and Shape:Solid
    Molecular weight:419.50

    Ref: TM-T200457

  • GSK-3β inhibitor 25
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    GSK-3β inhibitor 25

    CAS:
    <p>GSK-3β inhibitor25 (Compound 6h) exhibits weak inhibitory activity against GSK-3β with an IC50 greater than 100 μM.</p>
    Formula:C16H15NOS
    Color and Shape:Solid
    Molecular weight:269.361

    Ref: TM-T204501

  • GSK3-IN-9
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    GSK3-IN-9

    CAS:
    <p>GSK3-IN-9 (0713) is a selective inhibitor of glycogen synthase kinase 3 (GSK3). It holds potential for research into fragile X syndrome, attention deficit hyperactivity disorder (ADHD), childhood epilepsy, intellectual disabilities, diabetes, acute myeloid leukemia (AML), autism, and mental disorders.</p>
    Formula:C18H20N4O
    Color and Shape:Solid
    Molecular weight:308.378

    Ref: TM-T205647

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    GSK-3β inhibitor 7

    <p>GSK-3β inhibitor 7 is a GSK-3β inhibitor (IC50: 5.25 μM).</p>
    Formula:C27H23BrN4O2S
    Color and Shape:Solid
    Molecular weight:547.47

    Ref: TM-T63866

  • CymitQuimica logo
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    GSK-3β inhibitor 6

    <p>GSK-3β inhibitor 6 is a highly potent inhibitor of GSK-3β, with an IC50 value of 24.4 μM.</p>
    Formula:C20H17BrN4
    Color and Shape:Solid
    Molecular weight:393.28

    Ref: TM-T61804

  • Bisindolylmaleimide I HCl
    Targetmol
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    Bisindolylmaleimide I HCl

    CAS:
    <p>Bisindolylmaleimide I HCl is a specific ATP-competitive PKC inhibitor.</p>
    Formula:C25H25ClN4O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:448.95

    Ref: TM-T26826

    50mg
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    100mg
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    Discontinued product