gsk-3
GSK-3 inhibitors are compounds that target Glycogen Synthase Kinase 3 (GSK-3), an enzyme involved in numerous cellular processes, including glycogen metabolism, gene transcription, and cell proliferation. GSK-3 is implicated in various diseases, such as diabetes, neurodegenerative disorders, and cancer. Inhibitors of GSK-3 are important tools for exploring these pathways and developing potential therapies. At CymitQuimica, we provide GSK-3 inhibitors to support your research in metabolic diseases, neurobiology, and oncology.
Read more
RGB-286638 free base
CAS:784210-88-4
RGB-286638 free base inhibits CDKs (1-5 nM), weaker on CDK7/6.
Formula:
C29H35N7O4
Purity:
97.29% - 99.91%
Color and Shape:
Solid
Molecular weight:
545.63
Ref: TM-T2378
| 1mg | 46.00 € | ||
| 2mg | 60.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 144.00 € | ||
| 25mg | 263.00 € | ||
| 50mg | 396.00 € | ||
| 100mg | 554.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
AZD1080
CAS:612487-72-6
AZD1080 is a selective, orally active, brain permeable GSK3 inhibitor.
Formula:
C19H18N4O2
Purity:
97.72% - 99.68%
Color and Shape:
Solid
Molecular weight:
334.37
Ref: TM-T1741
| 1mg | 42.00 € | ||
| 2mg | 55.00 € | ||
| 5mg | 83.00 € | ||
| 10mg | 122.00 € | ||
| 25mg | 215.00 € | ||
| 50mg | 344.00 € | ||
| 100mg | 421.00 € | ||
| 1mL*10mM (DMSO) | 63.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
TDZD-8
CAS:327036-89-5
TDZD-8 (NP 01139) is an inhibitor of GSK-3β, with an IC50 of 2 μM; minimal …
Formula:
C10H10N2O2S
Purity:
97.13% - 99.48%
Color and Shape:
White Solid
Molecular weight:
222.26
Ref: TM-T6187
| 5mg | 49.00 € | ||
| 10mg | 57.00 € | ||
| 25mg | 83.00 € | ||
| 50mg | 122.00 € | ||
| 100mg | 184.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
SB 216763
CAS:280744-09-4
SB 216763 (SB216763) is an effective and specific GSK-3α/β inhibitor (IC50: 34.3 nM).
Formula:
C19H12Cl2N2O2
Purity:
99.13% - 99.61%
Color and Shape:
Solid
Molecular weight:
371.22
Ref: TM-T3077
| 2mg | 39.00 € | ||
| 5mg | 52.00 € | ||
| 10mg | 78.00 € | ||
| 25mg | 128.00 € | ||
| 50mg | 193.00 € | ||
| 100mg | 326.00 € | ||
| 500mg | 789.00 € | ||
| 1mL*10mM (DMSO) | 53.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
CP21R7
CAS:125314-13-8
CP21 is a specific GSK3β inhibitor, used to activate stem cells for differentiation, often paired …
Formula:
C19H15N3O2
Purity:
96.14% - 98.21%
Color and Shape:
Solid
Molecular weight:
317.34
Ref: TM-T3684
| 1mg | 62.00 € | ||
| 2mg | 84.00 € | ||
| 5mg | 95.00 € | ||
| 10mg | 152.00 € | ||
| 25mg | 267.00 € | ||
| 50mg | 453.00 € | ||
| 100mg | 662.00 € | ||
| 1mL*10mM (DMSO) | 81.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
VP3.15 dihydrobromide
CAS:1281681-33-1
VP3.15 dihydrobromide: potent, oral, CNS-penetrant PDE7/GSK3 inhibitor; IC50s: PDE7- 1.59 μM, GSK- 0.88 μM.
Formula:
C20H24Br2N4OS
Purity:
96.68% - ≥95%
Color and Shape:
Solid
Molecular weight:
528.3
Ref: TM-T5956
| 2mg | 46.00 € | ||
| 5mg | 70.00 € | ||
| 10mg | 95.00 € | ||
| 25mg | 214.00 € | ||
| 50mg | 372.00 € | ||
| 100mg | 553.00 € | ||
| 500mg | 1,194.00 € | ||
| 1mL*10mM (DMSO) | 81.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
CHIR-99021
CAS:252917-06-9
View and buy CHIR-99021 from TargetMol.CHIR-99021 is a GSK-3α/β inhibitor.Cited in 10 publications.
Formula:
C22H18Cl2N8
Purity:
97.94% - ≥95%
Color and Shape:
Solid
Molecular weight:
465.34
Ref: TM-T2310
| 2mg | 48.00 € | ||
| 5mg | 69.00 € | ||
| 10mg | 92.00 € | ||
| 25mg | 165.00 € | ||
| 50mg | 259.00 € | ||
| 100mg | 409.00 € | ||
| 200mg | 608.00 € | ||
| 500mg | 941.00 € | ||
| 1mL*10mM (DMSO) | 70.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Indirubin-3′-oxime
CAS:667463-82-3
Indirubin-3′-oxime is an effective inhibitor of cyclin-dependent protein kinases, and may play an obligate role …
Formula:
C16H11N3O2
Purity:
98.34%
Color and Shape:
Solid
Molecular weight:
277.28
Ref: TM-T9138
| 1mg | 46.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 145.00 € | ||
| 25mg | 275.00 € | ||
| 50mg | 424.00 € | ||
| 100mg | 625.00 € | ||
| 1mL*10mM (DMSO) | 121.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
TBB
CAS:17374-26-4
TBB (NSC-231634)(NSC-231634) is a highly selective, ATP/GTP-competitive inhibitor of casein kinase-2 (CK2).
Formula:
C6HBr4N3
Purity:
98.51% - 99.45%
Color and Shape:
Off-White Solid
Molecular weight:
434.71
Ref: TM-T2695
| 5mg | 45.00 € | ||
| 10mg | 58.00 € | ||
| 25mg | 73.00 € | ||
| 50mg | 87.00 € | ||
| 100mg | 119.00 € | ||
| 200mg | 173.00 € | ||
| 1mL*10mM (DMSO) | 35.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Kaempferol 3-neohesperidoside
CAS:32602-81-6
Kaempferol 3-neohesperidoside (Kaempferol 3-O-neohesperidoside), a flavonoid compound, demonstrates an insulinomimetic effect on the rat soleus …
Formula:
C27H30O15
Purity:
98.34%
Color and Shape:
Solid
Molecular weight:
594.52
Ref: TM-TN1819
| 1mg | 60.00 € | ||
| 5mg | 124.00 € | ||
| 10mg | 183.00 € | ||
| 25mg | 308.00 € | ||
| 50mg | 461.00 € | ||
| 100mg | 643.00 € | ||
| 1mL*10mM (DMSO) | 163.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Indirubin-3'-monoxime
CAS:160807-49-8
Indirubin-3'-monoxime (Indirubin-3'-oxime) is a potent inhibitor of GSK3β (IC50: 22 nM) and also inhibits CDKs …
Formula:
C16H11N3O2
Purity:
99.65%
Color and Shape:
Dark Red Solid
Molecular weight:
277.28
Ref: TM-T5200
| 1mg | 35.00 € | ||
| 5mg | 68.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 186.00 € | ||
| 50mg | 294.00 € | ||
| 100mg | 438.00 € | ||
| 1mL*10mM (DMSO) | 73.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
KY19382
CAS:2226664-93-1
KY19382, a dual CXXC5-DVL and GSK3β inhibitor (IC50s: 19/10 nM), boosts Wnt/β-catenin signaling and may …
Formula:
C17H11Cl2N3O2
Purity:
98.06%
Color and Shape:
Solid
Molecular weight:
360.19
Ref: TM-T9025
| 1mg | 100.00 € | ||
| 5mg | 199.00 € | ||
| 10mg | 354.00 € | ||
| 25mg | 597.00 € | ||
| 50mg | 849.00 € | ||
| 100mg | 1,142.00 € | ||
| 500mg | 2,256.00 € | ||
| 1mL*10mM (DMSO) | 245.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
IM-12
CAS:1129669-05-1
IM-12, an effective GSK-3β inhibitor(IC50=53 nM), regulates Wnt signalling.
Formula:
C22H20FN3O2
Purity:
100% - 99.71%
Color and Shape:
Solid
Molecular weight:
377.41
Ref: TM-T2261
| 5mg | 53.00 € | ||
| 10mg | 87.00 € | ||
| 25mg | 155.00 € | ||
| 50mg | 282.00 € | ||
| 100mg | 468.00 € | ||
| 500mg | 1,016.00 € | ||
| 1mL*10mM (DMSO) | 58.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Tideglusib
CAS:865854-05-3
Tideglusib (NP031112), a non-ATP competitive inhibitor of glycogen synthase kinase 3 (GSK-3), is with anti-inflammatory …
Formula:
C19H14N2O2S
Purity:
98.89% - 99.84%
Color and Shape:
Solid
Molecular weight:
334.39
Ref: TM-T3067
| 10mg | 46.00 € | ||
| 25mg | 76.00 € | ||
| 50mg | 112.00 € | ||
| 100mg | 185.00 € | ||
| 200mg | 279.00 € | ||
| 500mg | 482.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
LY2090314
CAS:603288-22-8
LY2090314, a potent GSK-3α/β blocker (IC50: 1.5/0.9 nM), could boost platinum chemo. Tested in leukemia …
Formula:
C28H25FN6O3
Purity:
99.03% - 99.88%
Color and Shape:
Solid
Molecular weight:
512.53
Ref: TM-T1755
| 1mg | 48.00 € | ||
| 2mg | 62.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 149.00 € | ||
| 25mg | 260.00 € | ||
| 50mg | 423.00 € | ||
| 100mg | 624.00 € | ||
| 1mL*10mM (DMSO) | 107.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
GS87
CAS:919936-70-2
GS87 is a highly specific inhibitor of GSK3 (glycogen synthase kinase 3) that induces extensive …
Formula:
C16H11N5O2S
Purity:
98.86%
Color and Shape:
Solid
Molecular weight:
337.36
Ref: TM-T8605
| 1mg | 130.00 € | ||
| 2mg | 185.00 € | ||
| 5mg | 279.00 € | ||
| 10mg | 425.00 € | ||
| 25mg | 701.00 € | ||
| 50mg | 985.00 € | ||
| 100mg | 1,332.00 € | ||
| 1mL*10mM (DMSO) | 294.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
AZD2858
CAS:486424-20-8
AZD2858 is a selective GSK-3 inhibitor, inhibiting tau phosphorylation at the S396 site and activating …
Formula:
C21H23N7O3S
Purity:
98% - 99.25%
Color and Shape:
Solid
Molecular weight:
453.52
Ref: TM-T1957
| 1mg | 38.00 € | ||
| 2mg | 49.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 104.00 € | ||
| 25mg | 194.00 € | ||
| 50mg | 365.00 € | ||
| 100mg | 544.00 € | ||
| 500mg | 1,180.00 € | ||
| 1mL*10mM (DMSO) | 108.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
BIO-acetoxime
CAS:667463-85-6
BIO-acetoxime (GSK-3 Inhibitor X) is a potent dual GSK3α/β inhibitor with IC50 of 10 nM, …
Formula:
C18H12BrN3O3
Purity:
97.28%
Color and Shape:
Solid
Molecular weight:
398.21
Ref: TM-T6787
| 1mg | 41.00 € | ||
| 2mg | 53.00 € | ||
| 5mg | 71.00 € | ||
| 10mg | 105.00 € | ||
| 25mg | 188.00 € | ||
| 50mg | 298.00 € | ||
| 100mg | 465.00 € | ||
| 1mL*10mM (DMSO) | 78.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Bikinin
CAS:188011-69-0
Bikinin (Abrasin), a potent inhibitor of plant GSK-3/Shaggy-like kinase, activates BR signaling downstream of the …
Formula:
C9H9BrN2O3
Purity:
100% - 99.91%
Color and Shape:
Solid
Molecular weight:
273.08
Ref: TM-T1965
| 10mg | 46.00 € | ||
| 25mg | 76.00 € | ||
| 50mg | 118.00 € | ||
| 100mg | 183.00 € | ||
| 200mg | 272.00 € | ||
| 500mg | 462.00 € | ||
| 1mL*10mM (DMSO) | 35.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
SB 415286
CAS:264218-23-7
SB 415286 is a potent GSK3α inhibitor with IC50/Ki of 78 nM/31 nM with equally …
Formula:
C16H10ClN3O5
Purity:
99.56%
Color and Shape:
Solid
Molecular weight:
359.72
Ref: TM-T6659
| 5mg | 48.00 € | ||
| 10mg | 70.00 € | ||
| 25mg | 126.00 € | ||
| 50mg | 201.00 € | ||
| 100mg | 328.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
