AMPK
AMPK inhibitors are compounds that target and inhibit AMP-Activated Protein Kinase (AMPK), an enzyme that plays a critical role in cellular energy homeostasis. AMPK is activated in response to low energy levels in cells and helps regulate processes such as glucose uptake, fatty acid oxidation, and mitochondrial biogenesis. Inhibiting AMPK is important for studying its role in metabolic diseases, cancer, and aging. At CymitQuimica, we offer a range of AMPK inhibitors to support your research in metabolism, oncology, and age-related diseases.
Found 158 products of "AMPK"
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XY221
<p>XY221 (Compound 16o) selectively inhibits BRD4 BD2 with an IC50 of 5.8 nM. It demonstrates high selectivity for pan-BD2 and BRD4 BD2 domains, being 667 times more selective than for BRD4 BD1, and 9-32 times more selective than for BRD2/3/T BD2. XY221 can induce apoptosis in MV4-11 cells and exhibits anti-cancer activity.</p>Formula:C32H34FN3O5Color and Shape:SolidMolecular weight:559.628AMPK-IN-6
<p>AMPK-IN-6 (compound 13a) is a potent AMPK inhibitor with an IC50 value of 0.093 µM. It induces apoptosis and suppresses autophagy. Additionally, AMPK-IN-6 exhibits antiproliferative activity and holds potential for research into pulmonary arterial hypertension.</p>Formula:C18H20FN5OColor and Shape:SolidMolecular weight:341.383SAMS
CAS:<p>SAMS peptide is a specific substrate for the AMP-activated protein kinase (AMPK).</p>Formula:C74H131N29O18S2Purity:98%Color and Shape:SolidMolecular weight:1779.15ALKBH1-IN-3
<p>ALKBH1-IN-3 is an effective inhibitor of the DNA N6-methyladenosine (6mA) demethylase ALKBH1. This compound enhances the abundance of 6mA in gastric cancer cell lines HGC27 and AGS, simultaneously inhibiting cell viability and upregulating the AMP-activated protein kinase (AMPK) signaling pathway. ALKBH1-IN-3 holds potential for use in cancer research, including studies on gastric cancer.</p>Color and Shape:Odour SolidGlycometabolism Compound Library
<p>xnum glycometabolism-related comounds, can be used for HTS and HCT;</p>Color and Shape:Odour SolidSTO-609 acetate
CAS:<p>STO-609 acetate is selective, cell-permeable inhibitor of Ca2+-calmodulin-dependent protein kinase kinase (Ki: 80/15 ng/ml, for CaM-KKα/KKβ); competes for the</p>Formula:C19H10N2O3·C2H4O2Purity:99.75%Color and Shape:SolidMolecular weight:374.35AMPK activator 15
<p>AP39 Prodrug 1 (Compound M1) is a mitochondria-targeted H2S prodrug. In hepatocytes, it induces ROS-dependent mild mitochondrial uncoupling, activates mitochondria-associated AMPK, and inhibits Palmitic acid (PA)-induced lipid accumulation.</p>Formula:C53H51BrNO10PSColor and Shape:SolidMolecular weight:1004.92Anti-Phospho-AMPKα (Thr172) Antibody (3O988)
<p>Anti-Phospho-AMPKα (Thr172) Antibody (3O988) is a Rabbit antibody targeting Phospho-AMPKα (Thr172). Anti-Phospho-AMPKα (Thr172) Antibody (3O988) can be used in WB.</p>Color and Shape:Odour LiquidMetformin-d6 hydrochloride
CAS:<p>Metformin-d6 hydrochloride (Metformin-d6 hydrochloride) is a deuteride of Metformin, which can be used to study Metformin metabolism in vivo.</p>Formula:C4H12ClN5Purity:98.1%Color and Shape:SolidMolecular weight:171.666-Azuridine
CAS:<p>6-Azauridine is a purine analog with antitumor effects, inhibiting DNA synthesis and inducing apoptosis in lymphatic cancers.</p>Formula:C8H11N3O6Purity:>99.99%Color and Shape:SolidMolecular weight:245.19Metformin
CAS:<p>Metformin (1,1-Dimethylbiguanide) is an AMPK activator with blood-brain barrier permeability.</p>Formula:C4H11N5Purity:99.77% - >99.99%Color and Shape:SolidMolecular weight:129.16COH-SR4
CAS:<p>COH-SR4 (COH-SR4 (Mitochondria uncoupler SR4)) is a uncoupler of mitochondrial oxidative phosphorylation.</p>Formula:C13H8Cl4N2OPurity:98.96%Color and Shape:SolidMolecular weight:350.03O-304
CAS:<p>O-304 is a pan-activator of AMP-activated protein kinase (AMPK).</p>Formula:C16H11Cl2N3O2SPurity:99.84% - ≥98%Color and Shape:SolidMolecular weight:380.25AMPK activator 2
CAS:<p>AMPK activator 2, a chloroformin derivative, may boost cancer treatment by enhancing AMPK and inhibiting mTOR pathways, and cancer cell growth.</p>Formula:C13H18F3N5Purity:99.86%Color and Shape:SolidMolecular weight:301.31GSK621
CAS:<p>GSK621 is a specific and potent AMPK activator.</p>Formula:C26H20ClN3O5Purity:97.02% - 97.05%Color and Shape:SolidMolecular weight:489.91Bempedoic acid
CAS:<p>Bempedoic acid (ETC1002) is an orally available, once-daily LDL-C lowering small molecule designed to lower elevated levels of LDL-C.</p>Formula:C19H36O5Purity:99.85% - 99.94%Color and Shape:SolidMolecular weight:344.49Mogroside I E1
CAS:<p>Mogroside I E1 is a triterpenoid glycoside isolated from the extracts of Luo Han Guo, is a nonsugar sweetener.</p>Formula:C36H62O9Purity:98.62% - 99.71%Color and Shape:SolidMolecular weight:638.87Kahweol
CAS:<p>Kahweol has anticarcinogenic, anti-angiogenic,and anti-inflammatory activities, it can block the LPS-induced activation of NF-kappaB by preventing IkappaB</p>Formula:C20H26O3Purity:99.26% - 99.86%Color and Shape:Off-White To Yellow SolidMolecular weight:314.42BC1618
CAS:<p>BC1618 (2-Propanol, 1-[bis(phenylmethyl)amino]-3-[4-(trifluoromethyl)phenoxy]-) is an orally active Fbxo48 inhibitor that stimulates Ampk-dependent signaling.</p>Formula:C24H24F3NO2Purity:99.95%Color and Shape:SolidMolecular weight:415.45EB-3D
CAS:<p>EB-3D is a potent and selective choline kinase alpha 1 (ChoKα1) inhibitor(IC50 : 1 μM).with anti-cancer activity.</p>Formula:C30H36Br2N4O2Purity:99.48%Color and Shape:SolidMolecular weight:644.4
