AMPK
AMPK inhibitors are compounds that target and inhibit AMP-Activated Protein Kinase (AMPK), an enzyme that plays a critical role in cellular energy homeostasis. AMPK is activated in response to low energy levels in cells and helps regulate processes such as glucose uptake, fatty acid oxidation, and mitochondrial biogenesis. Inhibiting AMPK is important for studying its role in metabolic diseases, cancer, and aging. At CymitQuimica, we offer a range of AMPK inhibitors to support your research in metabolism, oncology, and age-related diseases.
Found 168 products of "AMPK"
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XY221
XY221 (Compound 16o) selectively inhibits BRD4 BD2 with an IC50 of 5.8 nM. It demonstrates high selectivity for pan-BD2 and BRD4 BD2 domains, being 667 times more selective than for BRD4 BD1, and 9-32 times more selective than for BRD2/3/T BD2. XY221 can induce apoptosis in MV4-11 cells and exhibits anti-cancer activity.Formula:C32H34FN3O5Color and Shape:SolidMolecular weight:559.628AMPK-IN-6
AMPK-IN-6 (compound 13a) is a potent AMPK inhibitor with an IC50 value of 0.093 µM. It induces apoptosis and suppresses autophagy. Additionally, AMPK-IN-6 exhibits antiproliferative activity and holds potential for research into pulmonary arterial hypertension.Formula:C18H20FN5OColor and Shape:SolidMolecular weight:341.383Flindersine
CAS:Flindersine is a useful organic compound for research related to life sciences. The catalog number is T124718 and the CAS number is 523-64-8.Formula:C14H13NO2Color and Shape:SolidMolecular weight:227.263AMARA peptide
CAS:AMARA peptide: a minimal substrate for SIK, AMPK, and other protein kinases; contains AMPK phosphorylation site.Formula:C62H115N27O17SPurity:98%Color and Shape:SolidMolecular weight:1542.81NUAK1-IN-2
NUAK1-IN-2 (Compound 24) is an inhibitor of NUAK1 with an IC50 of 3.162 nM, as well as an inhibitor of CDK2/4/6. It is applicable in research related to cancer, neurodevelopmental disorders, and Alzheimer's disease.Formula:C24H30N6OColor and Shape:SolidMolecular weight:418.535STO-609 acetate
CAS:STO-609 acetate is selective, cell-permeable inhibitor of Ca2+-calmodulin-dependent protein kinase kinase (Ki: 80/15 ng/ml, for CaM-KKα/KKβ); competes for theFormula:C19H10N2O3·C2H4O2Purity:99.75%Color and Shape:SolidMolecular weight:374.35ALKBH1-IN-3 prodrug
<p>ALKBH1-IN-4 prodrug (Compound 29E) is a prodrug of an inhibitor targeting the DNA N6-methyladenine demethylase enzyme ALKBH1. It works by significantly increasing the cellular abundance of 6mA and enhancing the AMPK signaling pathway, which suppresses the vitality of gastric cancer cells. ALKBH1-IN-4 prodrug displays excellent cellular activity and favorable metabolic exposure in vivo, making it a promising candidate for research in gastric cancer-related areas.</p>Color and Shape:Odour SolidSAMS
CAS:SAMS peptide is a specific substrate for the AMP-activated protein kinase (AMPK).Formula:C74H131N29O18S2Purity:98%Color and Shape:SolidMolecular weight:1779.15ALKBH1-IN-3
<p>ALKBH1-IN-3 is an effective inhibitor of the DNA N6-methyladenosine (6mA) demethylase ALKBH1. This compound enhances the abundance of 6mA in gastric cancer cell lines HGC27 and AGS, simultaneously inhibiting cell viability and upregulating the AMP-activated protein kinase (AMPK) signaling pathway. ALKBH1-IN-3 holds potential for use in cancer research, including studies on gastric cancer.</p>Color and Shape:Odour SolidGlycometabolism Compound Library
<p>xnum glycometabolism-related comounds, can be used for HTS and HCT;</p>Color and Shape:Odour SolidKanglexin
CAS:Kanglexin is an orally active novel anthraquinone compound. It inhibits NLRP3 inflammasome activation and pyroptosis, offering cardioprotective benefits. By stimulating the FGFR1/ERK signaling pathway, Kanglexin promotes angiogenesis and accelerates wound healing in diabetes. Additionally, it has lipid-lowering effects and inhibits vascular smooth muscle cell dedifferentiation, making it a potential compound for studying hyperlipidemia, fatty liver, and atherosclerosis.Formula:C21H18O8Molecular weight:398.36Anti-Phospho-AMPKα (Thr172) Antibody (3O988)
Anti-Phospho-AMPKα (Thr172) Antibody (3O988) is a Rabbit antibody targeting Phospho-AMPKα (Thr172). Anti-Phospho-AMPKα (Thr172) Antibody (3O988) can be used in WB.Color and Shape:Odour LiquidMetformin-d6 hydrochloride
CAS:Metformin-d6 hydrochloride (Metformin-d6 hydrochloride) is a deuteride of Metformin, which can be used to study Metformin metabolism in vivo.Formula:C4H12ClN5Purity:98.1%Color and Shape:SolidMolecular weight:171.66Teneligliptin hydrobromide hydrate
CAS:Teneligliptin hydrobromide hydrate: potent, long-lasting DPP-4 inhibitor with ~1 nM IC50.Formula:C22H33BrN6O2SColor and Shape:SolidMolecular weight:525.51Pyraclostrobin (Standard)
CAS:Pyraclostrobin (Standard) is the standard substance of Pyraclostrobin, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Pyraclostrobin is one of the most heavily used fungicides that inhibits mitochondrial complex III of fungal and mammalian cells.Formula:C19H18ClN3O4Molecular weight:387.826-Azuridine
CAS:<p>6-Azauridine is a purine analog with antitumor effects, inhibiting DNA synthesis and inducing apoptosis in lymphatic cancers.</p>Formula:C8H11N3O6Purity:>99.99%Color and Shape:SolidMolecular weight:245.19BC1618
CAS:<p>BC1618 (2-Propanol, 1-[bis(phenylmethyl)amino]-3-[4-(trifluoromethyl)phenoxy]-) is an orally active Fbxo48 inhibitor that stimulates Ampk-dependent signaling.</p>Formula:C24H24F3NO2Purity:99.95%Color and Shape:SolidMolecular weight:415.45Metformin
CAS:<p>Metformin (1,1-Dimethylbiguanide) is an AMPK activator with blood-brain barrier permeability.</p>Formula:C4H11N5Purity:99.77% - >99.99%Color and Shape:SolidMolecular weight:129.16COH-SR4
CAS:<p>COH-SR4 (COH-SR4 (Mitochondria uncoupler SR4)) is a uncoupler of mitochondrial oxidative phosphorylation.</p>Formula:C13H8Cl4N2OPurity:98.96%Color and Shape:SolidMolecular weight:350.03Kahweol
CAS:Kahweol has anticarcinogenic, anti-angiogenic,and anti-inflammatory activities, it can block the LPS-induced activation of NF-kappaB by preventing IkappaBFormula:C20H26O3Purity:99.26% - 99.86%Color and Shape:Off-White To Yellow SolidMolecular weight:314.42
