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AMPK

AMPK

AMPK inhibitors are compounds that target and inhibit AMP-Activated Protein Kinase (AMPK), an enzyme that plays a critical role in cellular energy homeostasis. AMPK is activated in response to low energy levels in cells and helps regulate processes such as glucose uptake, fatty acid oxidation, and mitochondrial biogenesis. Inhibiting AMPK is important for studying its role in metabolic diseases, cancer, and aging. At CymitQuimica, we offer a range of AMPK inhibitors to support your research in metabolism, oncology, and age-related diseases.

Found 158 products of "AMPK"

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  • AMPK activator 12
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    AMPK activator 12

    CAS:
    <p>AMPK activator 12 is an AMPK activator and GDF15 inducer that elevates the expression level of GDF15 protein for cancer research.</p>
    Formula:C23H24BrNO2
    Purity:99.55%
    Color and Shape:Solid
    Molecular weight:426.35

    Ref: TM-T78791

  • OSU-53
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    OSU-53

    CAS:
    <p>OSU-53 is an AMPK activator, inhibiting mTOR signaling and autophagy stimulation. OSU-53 also activates mutations in RAS or BRAF.</p>
    Formula:C25H24F3N3O6S2
    Color and Shape:Solid
    Molecular weight:583.6

    Ref: TM-T71051

  • AMPK activator
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    AMPK activator

    CAS:
    <p>AMPK activator</p>
    Formula:C22H21FO4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:368.4

    Ref: TM-T22567

  • AMPK activator 1
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    AMPK activator 1

    CAS:
    <p>AMPK activator 1 is an AMPK activator(compound No.1-75, EC50: &lt;0.1μM).</p>
    Formula:C32H33F3N4O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:578.62

    Ref: TM-T10069

  • HL271
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    HL271

    CAS:
    <p>HL271, a derivative of metformin, is a potent AMPK activator that increases AMPK phosphorylation. HL271 attenuates aging-associated cognitive impairment.</p>
    Formula:C13H17ClF3N5O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:351.76

    Ref: TM-T11570

  • MARK-IN-4
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    MARK-IN-4

    CAS:
    <p>MARK-IN-4 inhibits microtubule kinase (MARK) effectively (IC50: 1 nM), a target for Alzheimer's therapy.</p>
    Formula:C21H23N7OS
    Color and Shape:Solid
    Molecular weight:421.52

    Ref: TM-T62251

  • IND 1316
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    IND 1316

    CAS:
    <p>IND 1316 is an activator of AMP-activated protein kinase (AMPK).</p>
    Formula:C22H17NO3
    Color and Shape:Solid
    Molecular weight:343.38

    Ref: TM-T70085

  • AMPK activator 4
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    AMPK activator 4

    CAS:
    <p>Potent, selective AMPK activator 4 enhances glucose tolerance and insulin sensitivity without affecting mitochondrial complex I.</p>
    Formula:C24H21ClN2O3
    Purity:99.46% - 99.65%
    Color and Shape:Solid
    Molecular weight:420.89

    Ref: TM-T62238

  • ULK1-IN-2
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    ULK1-IN-2

    CAS:
    <p>ULK1-IN-2, a potent anticancer agent, inhibits ULK1, induces apoptosis, blocks autophagy, and shows high cytotoxicity with an IC50 of 1.94 μM in A549 cells.</p>
    Formula:C19H16BrFN4O6
    Purity:99.25% - 99.25%
    Color and Shape:Solid
    Molecular weight:495.26

    Ref: TM-T63343

  • YM-53601 free base
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    YM-53601 free base

    CAS:
    <p>YM-53601 free base is an inhibitor of squalene synthetase which suppresses lipogenic biosynthesis and lipid secretion in rodents.</p>
    Formula:C21H21FN2O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:336.4

    Ref: TM-T13371

  • AMPK activator 11
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    AMPK activator 11

    CAS:
    <p>AMPK Activator 11 is a nanomolar potent inhibitor of cell proliferation in various colorectal carcinomas (CRCs), acting through the selective activation of AMP-</p>
    Formula:C25H20N4O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:408.45

    Ref: TM-T79226

  • LRRK2/NUAK1/TYK2-IN-1
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    LRRK2/NUAK1/TYK2-IN-1

    CAS:
    <p>LRRK2/NUAK1/TYK2-IN-1 inhibits LRRK2, TYK2, NUAK1 with IC50 &lt; 10 nM, useful in autoimmune research.</p>
    Formula:C20H11F3N6
    Color and Shape:Solid
    Molecular weight:392.34

    Ref: TM-T72421

  • Galegine hydrochloride
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    Galegine hydrochloride

    CAS:
    <p>Galegine hydrochloride, from G. officinalis, leads to weight loss, activates AMPK in various cells, and has antibacterial properties.</p>
    Formula:C6H14ClN3
    Color and Shape:Solid
    Molecular weight:163.65

    Ref: TM-T35532

  • GL-V9
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    GL-V9

    CAS:
    <p>GL-V9 is an AMPK activator, protecting against colitis-associated colorectal cancer by limiting NLRP3 inflammasome through autophagy.</p>
    Formula:C24H27NO5
    Color and Shape:Solid
    Molecular weight:409.47

    Ref: TM-T71314

  • SMTIN-T140
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    SMTIN-T140

    CAS:
    <p>SMTIN-T140: strong TRAP1 inhibitor, IC50=1.646μM, anticancer; disrupts mitochondria, boosts ROS, activates AMPK, shrinks PC3 tumors, no in vivo toxicity.</p>
    Formula:C36H34BrClFN5OP
    Purity:98%
    Color and Shape:Solid
    Molecular weight:718.02

    Ref: TM-T73125

  • DK419
    Targetmol
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    DK419

    CAS:
    <p>DK419 is an orally active inhibitor of Wnt/β-catenin signaling, with an IC50 of 0.19 μM.</p>
    Formula:C16H8ClF6N3O
    Purity:99.63%
    Color and Shape:Solid
    Molecular weight:407.7

    Ref: TM-T15137

  • YLF-466D
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    YLF-466D

    CAS:
    <p>YLF-466D (C24) is a newly developed AMPK activator, which inhibits platelet aggregation.</p>
    Formula:C29H20ClNO3
    Purity:97.74%
    Color and Shape:Solid
    Molecular weight:465.93

    Ref: TM-T13368

  • PF-249
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    PF-249

    CAS:
    <p>PF-249 (PF-06685249) is a β1-selective AMPK with an EC50 of 12 nM for AMPK α1β1γ1 and can be used in studies about diabetic nephropathy.</p>
    Formula:C17H16ClN3O3
    Purity:97.01%
    Color and Shape:Solid
    Molecular weight:345.78

    Ref: TM-T24626

  • Butylate
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    Butylate

    CAS:
    <p>Butylate is a herbicide of thiocarbamate.</p>
    Formula:C11H23NOS
    Color and Shape:Less Liquid Which Darkens Upon Exposure To Light Air And Moisture Colorless Liquid Which Darkens Upon Exposure To Light Air And Moisture
    Molecular weight:217.37

    Ref: TM-T20529

  • MRT199665
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    MRT199665

    CAS:
    <p>MRT199665, a selective MARK/SIK/AMPK inhibitor, blocks SIK CRTC3 S370 phosphorylation and triggers apoptosis in AML cells.</p>
    Formula:C28H31N5O2
    Color and Shape:Solid
    Molecular weight:469.58

    Ref: TM-T16142