AMPK
AMPK inhibitors are compounds that target and inhibit AMP-Activated Protein Kinase (AMPK), an enzyme that plays a critical role in cellular energy homeostasis. AMPK is activated in response to low energy levels in cells and helps regulate processes such as glucose uptake, fatty acid oxidation, and mitochondrial biogenesis. Inhibiting AMPK is important for studying its role in metabolic diseases, cancer, and aging. At CymitQuimica, we offer a range of AMPK inhibitors to support your research in metabolism, oncology, and age-related diseases.
Found 159 products for "AMPK".
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LRRK2/NUAK1/TYK2-IN-1
CAS:LRRK2/NUAK1/TYK2-IN-1 inhibits LRRK2, TYK2, NUAK1 with IC50 < 10 nM, useful in autoimmune research.Formula:C20H11F3N6Color and Shape:SolidMolecular weight:392.34AMPK activator 11
CAS:AMPK Activator 11 is a nanomolar potent inhibitor of cell proliferation in various colorectal carcinomas (CRCs), acting through the selective activation of AMP-Formula:C25H20N4O2Purity:98%Color and Shape:SolidMolecular weight:408.45AMPK activator 6
CAS:AMPK activator 6 stimulates AMPK, lowers lipids in cells, and reduces serum TC, LDL-C, and TG. Useful for NAFLD and metabolic research.Formula:C25H28O5Color and Shape:SolidMolecular weight:408.49PF-739
CAS:PF-739 is an AMPK agonist that has been shown to activate AMPK in hepatocytes and skeletal muscle.Formula:C23H23ClN2O5Purity:98%Color and Shape:SolidMolecular weight:442.89AMPK activator 12
CAS:AMPK activator 12 is an AMPK activator and GDF15 inducer that elevates the expression level of GDF15 protein for cancer research.Formula:C23H24BrNO2Purity:99.57%Color and Shape:SolidMolecular weight:426.35AMDE-1
CAS:AMDE-1, an autophagy modulator, triggers Atg5-dependent autophagy, recruits Atg16, and induces LC3 lipidation.Formula:C18H8ClF6N3Purity:90%Color and Shape:SolidMolecular weight:415.72YM-53601 free base
CAS:YM-53601 free base is an inhibitor of squalene synthetase which suppresses lipogenic biosynthesis and lipid secretion in rodents.Formula:C21H21FN2OPurity:98%Color and Shape:SolidMolecular weight:336.4AMPK activator 1
CAS:AMPK activator 1 is an AMPK activator(compound No.1-75, EC50: <0.1μM).Formula:C32H33F3N4O3Purity:98%Color and Shape:SolidMolecular weight:578.62HL271
CAS:HL271 hydrochloride is a chemical derivative of metformin and a potent AMPK activator that enhances AMPK phosphorylation levels.Formula:C13H17ClF3N5OPurity:99.84%Color and Shape:SolidMolecular weight:351.76GL-V9
CAS:GL-V9 is an AMPK activator, protecting against colitis-associated colorectal cancer by limiting NLRP3 inflammasome through autophagy.Formula:C24H27NO5Color and Shape:SolidMolecular weight:409.47SMTIN-T140
CAS:SMTIN-T140: strong TRAP1 inhibitor, IC50=1.646μM, anticancer; disrupts mitochondria, boosts ROS, activates AMPK, shrinks PC3 tumors, no in vivo toxicity.Formula:C36H34BrClFN5OPPurity:98%Color and Shape:SolidMolecular weight:718.02IND 1316
CAS:IND 1316 is an activator of AMP-activated protein kinase (AMPK).Formula:C22H17NO3Color and Shape:SolidMolecular weight:343.38AMPK activator 8
CAS:AMPK activator 8 targets rAMPK α1β1γ1/α2β1γ1/α1β2γ1 (EC50: 11/27/4 nM) for type 2 diabetes research.Formula:C25H21ClN2O6Color and Shape:SolidMolecular weight:480.9XMD-17-51
CAS:XMD-17-51 has DCLK1 kinase inhibitory activity, inhibits DCLK1 and cell proliferation, and can be used in lung cancer research.Formula:C21H24N8OPurity:99.04%Color and Shape:SolidMolecular weight:404.47OSU-53
CAS:OSU-53 is an AMPK activator, inhibiting mTOR signaling and autophagy stimulation. OSU-53 also activates mutations in RAS or BRAF.Formula:C25H24F3N3O6S2Color and Shape:SolidMolecular weight:583.6AMPK activator 4
CAS:Potent, selective AMPK activator 4 enhances glucose tolerance and insulin sensitivity without affecting mitochondrial complex I.Formula:C24H21ClN2O3Purity:99.97% - 99.99%Color and Shape:SolidMolecular weight:420.89Ref: TM-T62238
1mg86.00€5mg173.00€1mL*10mM (DMSO)203.00€10mg334.00€25mg563.00€50mg802.00€100mg1,099.00€500mg2,187.00€DK419
CAS:DK419 is an orally active inhibitor of Wnt/β-catenin signaling, with an IC50 of 0.19 μM.Formula:C16H8ClF6N3OPurity:99.63%Color and Shape:White SolidMolecular weight:407.7AMPK-IN-3
CAS:AMPK-IN-3: potent, selective AMPK (α2/α1) & KDR inhibitor; IC50: 60.7/107/3820 nM; anticancer in K562 cells.Formula:C25H33N5O3Purity:97.25%Color and Shape:SolidMolecular weight:451.56PF-249
CAS:PF-249 (PF-06685249) is a β1-selective AMPK with an EC50 of 12 nM for AMPK α1β1γ1 and can be used in studies about diabetic nephropathy.Formula:C17H16ClN3O3Purity:97.01%Color and Shape:SolidMolecular weight:345.78Ref: TM-T24626
1mg46.00€5mg92.00€1mL*10mM (DMSO)100.00€10mg147.00€25mg236.00€50mg344.00€100mg482.00€200mg662.00€YLF-466D
CAS:YLF-466D (C24) is a newly developed AMPK activator, which inhibits platelet aggregation.Formula:C29H20ClNO3Purity:97.74%Color and Shape:SolidMolecular weight:465.93Ref: TM-T13368
1mg34.00€5mg79.00€1mL*10mM (DMSO)82.00€10mg111.00€25mg188.00€50mg269.00€100mg371.00€200mg512.00€
