PI3K
PI3K inhibitors are compounds that block the activity of Phosphoinositide 3-Kinases (PI3Ks), a family of enzymes involved in a wide range of cellular processes, including growth, proliferation, survival, and metabolism. The PI3K/Akt/mTOR pathway is often dysregulated in cancer, making PI3K a key target for cancer therapy. PI3K inhibitors are critical tools for studying signal transduction, cancer biology, and the development of targeted therapies. At CymitQuimica, we provide a variety of PI3K inhibitors to support your research in cell signaling, oncology, and therapeutic development.
Read more
GSK251
CAS:2125968-05-8
GSK251 is a novel, orally bioavailable inhibitor of PI3Kδ, exhibiting high potency and selectivity, with …
Formula:
C29H37FN6O4S
Purity:
98.9%
Color and Shape:
Solid
Molecular weight:
584.71
Ref: TM-T39573
| 1mg | 160.00 € | ||
| 5mg | 388.00 € | ||
| 10mg | 551.00 € | ||
| 25mg | 821.00 € | ||
| 50mg | 1,098.00 € | ||
| 100mg | 1,489.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
GSK2292767 FA
GSK2292767 FA: potent PI3Kδ inhibitor, pIC50=10.1, 500x selectivity, for respiratory research.
Formula:
C25H30N6O7S
Purity:
99.21%
Color and Shape:
Soild
Molecular weight:
558.61
Ref: TM-T6850L
| 1mg | 151.00 € | ||
| 5mg | 362.00 € | ||
| 10mg | 543.00 € | ||
| 25mg | 872.00 € | ||
| 50mg | 1,184.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
PITCOIN4
PITCOIN4 is a Class II Alpha PI3K-C2α inhibitor with high selectivity, demonstrating nanomolar inhibition of …
Purity:
98%
Ref: TM-T81453
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 5 Dec 2024
FD274
CAS:2641899-38-7
FD274 is a potent dual PI3K/mTOR inhibitor with inhibitory effects on PI3Kα/β/γ/δ and mTOR, with …
Formula:
C22H14ClFN6O2S
Purity:
98%
Color and Shape:
Soild
Molecular weight:
480.9
Ref: TM-T77629
| 1mg | 184.00 € | ||
| 5mg | 405.00 € | ||
| 10mg | 612.00 € | ||
| 25mg | 1,044.00 € | ||
| 50mg | 1,580.00 € | ||
| 100mg | 2,388.00 € | ||
| 500mg | 5,254.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
Anticancer agent 137
Anticancer agent 137 (8q), a potent PI3k inhibitor, exhibits broad-spectrum anticancer activity by inducing G2/M …
Formula:
C26H27NO6
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
449.5
Ref: TM-T79482
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 5 Dec 2024
PI3K-IN-47
PI3K-IN-47 (Compound 27) is a potent bivalent inhibitor targeting the phosphoinositide 3-kinases (PI3K) family, exhibiting …
Formula:
C50H46F4N8O8S2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
1027.07
Ref: TM-T78853
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 5 Dec 2024
Duvelisib (R enantiomer) hydrochloride
Duvelisib (R enantiomer) hydrochloride (INK1197 R enantiomer HCl) is a PI3K inhibitor.
Formula:
C22H18Cl2N6O
Purity:
99.76% - 99.87%
Color and Shape:
Soild
Molecular weight:
453.32
Ref: TM-T11129L
| 1mg | 306.00 € | ||
| 5mg | 744.00 € | ||
| 10mg | 1,019.00 € | ||
| 25mg | 1,542.00 € | ||
| 50mg | 2,070.00 € | ||
| 100mg | 2,732.00 € | ||
| 1mL*10mM (DMSO) | 936.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
THZ-P1-2
CAS:2058075-45-7
THZ-P1-2 is a PI5P4K inhibitor with anti-leukemic activity and can be used in the study …
Formula:
C31H29N7O2
Color and Shape:
Liquid
Molecular weight:
531.61
Ref: TM-T39459
| 1mg | 143.00 € | ||
| 5mg | 347.00 € | ||
| 10mg | 540.00 € | ||
| 25mg | 921.00 € | ||
| 50mg | 1,259.00 € | ||
| 100mg | 1,707.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
RLY-2608
CAS:2733573-94-7
RLY-2608 is a variant PI3Kalpha inhibitor that inhibits tumor growth in a PIK3CA mutant xenograft …
Formula:
C29H14ClF5N6O2
Purity:
98.7% - 98.96%
Color and Shape:
Liquid
Molecular weight:
608.91
Ref: TM-T81264
| 1mg | 502.00 € | ||
| 5mg | 997.00 € | ||
| 10mg | 1,612.00 € | ||
| 25mg | 2,404.00 € | ||
| 50mg | 3,243.00 € | ||
| 1mL*10mM (DMSO) | 1,331.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
740 Y-P
CAS:1236188-16-1
740 Y-P (740YPDGFR) is a potent and cell-permeable activator of PI3K.
Formula:
C141H222N43O39PS3
Purity:
98.3% - 99.87%
Color and Shape:
Solid
Molecular weight:
3270.7
Ref: TM-TQ0003
| 1mg | 97.00 € | ||
| 2mg | 135.00 € | ||
| 5mg | 249.00 € | ||
| 10mg | 368.00 € | ||
| 25mg | 615.00 € | ||
| 50mg | 876.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
SKI V
CAS:24418-86-8
SKI V is a potent and noncompetitive non-lipid sphingosine kinase (SPHK; SK) inhibitor (GST-hSK,IC50 : …
Formula:
C15H10O4
Purity:
98.78%
Color and Shape:
Solid
Molecular weight:
254.24
Ref: TM-T8461
| 1mg | 89.00 € | ||
| 5mg | 182.00 € | ||
| 10mg | 287.00 € | ||
| 25mg | 492.00 € | ||
| 50mg | 720.00 € | ||
| 100mg | 1,061.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
AS-252424
CAS:900515-16-4
AS-252424 is a potent and selective inhibitor of PI3Kγ with IC50 of 33 nM; >10 …
Formula:
C14H8FNO4S
Purity:
99.06% - 99.26%
Color and Shape:
Solid
Molecular weight:
305.28
Ref: TM-T6208
| 1mg | 39.00 € | ||
| 2mg | 50.00 € | ||
| 5mg | 80.00 € | ||
| 10mg | 132.00 € | ||
| 25mg | 213.00 € | ||
| 50mg | 319.00 € | ||
| 100mg | 462.00 € | ||
| 500mg | 1,009.00 € | ||
| 1mL*10mM (DMSO) | 89.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
PF-04691502
CAS:1013101-36-4
PF-04691502 is a potent and selective inhibitor of PI3K and mTOR kinases with antitumor activity.
Formula:
C22H27N5O4
Purity:
96.27% - ≥95%
Color and Shape:
Solid
Molecular weight:
425.48
Ref: TM-T6251
| 1mg | 36.00 € | ||
| 2mg | 45.00 € | ||
| 5mg | 66.00 € | ||
| 10mg | 92.00 € | ||
| 25mg | 123.00 € | ||
| 50mg | 195.00 € | ||
| 100mg | 347.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Oroxin B
CAS:114482-86-9
Oroxin B (Hypocretin-2) has antioxidant activity.
Formula:
C27H30O15
Purity:
98.22% - 98.33%
Color and Shape:
Solid
Molecular weight:
594.52
Ref: TM-T3780
| 20mg | 106.00 € | ||
| 1mL*10mM (DMSO) | 88.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
GDC0084
CAS:1382979-44-3
GDC0084 (RG7666) is a PI3K inhibitor with potential antineoplastic activity.
Formula:
C18H22N8O2
Purity:
99.16% - ≥95%
Color and Shape:
Solid
Molecular weight:
382.42
Ref: TM-T3705
| 2mg | 42.00 € | ||
| 5mg | 60.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 171.00 € | ||
| 50mg | 276.00 € | ||
| 100mg | 522.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
PIK-294
CAS:900185-02-6
PIK-294 is a excellently specific p110δ inhibitor(IC50=10 nM).
Formula:
C28H23N7O2
Purity:
100% - 99%
Color and Shape:
Solid
Molecular weight:
489.53
Ref: TM-T2297
| 1mg | 35.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 70.00 € | ||
| 10mg | 110.00 € | ||
| 25mg | 169.00 € | ||
| 50mg | 271.00 € | ||
| 100mg | 422.00 € | ||
| 1mL*10mM (DMSO) | 74.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
PF-4989216
CAS:1276553-09-3
PF-4989216 is a potent and selective PI3K inhibitor with IC50 of 2 nM, 142 nM, …
Formula:
C18H13FN6OS
Purity:
99.53%
Color and Shape:
Solid
Molecular weight:
380.4
Ref: TM-T6938
| 1mg | 47.00 € | ||
| 2mg | 60.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 167.00 € | ||
| 25mg | 309.00 € | ||
| 50mg | 542.00 € | ||
| 100mg | 654.00 € | ||
| 1mL*10mM (DMSO) | 100.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
1-Deoxynojirimycin
CAS:19130-96-2
1-Deoxynojirimycin (Moranoline) is a potent α-glucosidase inhibitor, suppressing postprandial blood glucose, thereby possibly preventing diabetes …
Formula:
C6H13NO4
Purity:
99.65% - 99.98%
Color and Shape:
White-Beige Solid Crystalline
Molecular weight:
163.17
Ref: TM-T3675
| 2mg | 45.00 € | ||
| 5mg | 60.00 € | ||
| 10mg | 78.00 € | ||
| 25mg | 144.00 € | ||
| 50mg | 256.00 € | ||
| 100mg | 332.00 € | ||
| 500mg | 798.00 € | ||
| 1mL*10mM (DMSO) | 60.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Eganelisib
CAS:1693758-51-8
Eganelisib (IPI-549) is an inhibitor of PI3Kγ (IC50 = 16, 3,200, 3,500, and >8,400 nM …
Formula:
C30H24N8O2
Purity:
98% - 99.56%
Color and Shape:
Solid
Molecular weight:
528.56
Ref: TM-T5432
| 5mg | 48.00 € | ||
| 10mg | 71.00 € | ||
| 25mg | 111.00 € | ||
| 50mg | 184.00 € | ||
| 100mg | 332.00 € | ||
| 500mg | 811.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
AMG 511
CAS:1253573-53-3
AMG 511: oral class I PI3K inhibitor (α, β, δ, γ Kis: 4, 6, 2, …
Formula:
C22H28FN9O3S
Purity:
≥98%
Color and Shape:
Solid
Molecular weight:
517.58
Ref: TM-T14214
| 1mg | 91.00 € | ||
| 2mg | 106.00 € | ||
| 5mg | 150.00 € | ||
| 10mg | To inquire | ||
| 50mg | To inquire | ||
| 1mL*10mM (DMSO) | 283.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
