PI3K
PI3K inhibitors are compounds that block the activity of Phosphoinositide 3-Kinases (PI3Ks), a family of enzymes involved in a wide range of cellular processes, including growth, proliferation, survival, and metabolism. The PI3K/Akt/mTOR pathway is often dysregulated in cancer, making PI3K a key target for cancer therapy. PI3K inhibitors are critical tools for studying signal transduction, cancer biology, and the development of targeted therapies. At CymitQuimica, we provide a variety of PI3K inhibitors to support your research in cell signaling, oncology, and therapeutic development.
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PI4KIIIbeta-IN-9
CAS:1429624-84-9
PI4KIIIbeta-IN-9 is a potent inhibitor of PI4KIIIβ(IC50 of 7 nM). .
Formula:
C23H25N3O5S2
Purity:
97.18%
Color and Shape:
Solid
Molecular weight:
487.59
Ref: TM-T12469
| 1mg | 79.00 € | ||
| 5mg | 186.00 € | ||
| 10mg | 279.00 € | ||
| 25mg | 505.00 € | ||
| 50mg | 707.00 € | ||
| 100mg | 926.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Inavolisib
CAS:2060571-02-8
Inavolisib (GDC-0077) is an orally available selective PI3Kα inhibitor with an IC50 value of 0.038 …
Formula:
C18H19F2N5O4
Purity:
97.36% - 99.75%
Color and Shape:
Solid
Molecular weight:
407.37
Ref: TM-T15375
| 1mg | 87.00 € | ||
| 5mg | 210.00 € | ||
| 10mg | 370.00 € | ||
| 25mg | 629.00 € | ||
| 50mg | 1,027.00 € | ||
| 100mg | 1,780.00 € | ||
| 1mL*10mM (DMSO) | 402.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
P110δ-IN-1
CAS:1595129-71-7
P110δ-IN-1 (PWT-143) is an effective and selective inhibitor of P110δ (IC50: 8.4 nM).
Formula:
C31H40N8O3S
Purity:
99.75%
Color and Shape:
Solid
Molecular weight:
604.77
Ref: TM-T16422
| 1mg | 47.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 150.00 € | ||
| 25mg | 277.00 € | ||
| 50mg | 526.00 € | ||
| 100mg | 737.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Sophocarpine monohydrate
CAS:145572-44-7
Sophocarpine monohydrate, a major ingredient of Sophora alopecuroides, has a wide range of pharmacological effects.
Formula:
C15H22N2O
Purity:
99.33%
Color and Shape:
Solid
Molecular weight:
246.35
Ref: TM-T2746
| 50mg | 54.00 € | ||
| 1mL*10mM (DMSO) | 49.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
PI4KIIIbeta-IN-10
CAS:1881233-39-1
PI4KIIIbeta-IN-10 is a potent inhibitor of PI4KIIIβ (IC50 of 3.6 nM).
Formula:
C22H25N3O5S2
Purity:
99.85%
Color and Shape:
Solid
Molecular weight:
475.58
Ref: TM-T12468
| 1mg | 78.00 € | ||
| 5mg | 159.00 € | ||
| 10mg | 246.00 € | ||
| 25mg | 406.00 € | ||
| 50mg | 542.00 € | ||
| 100mg | 762.00 € | ||
| 200mg | 1,025.00 € | ||
| 1mL*10mM (DMSO) | 167.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Pictilisib dimethanesulfonate
CAS:957054-33-0
Pictilisib dimethanesulfonate (GDC-0941 2 MeSO3H salt) is a potent inhibitor of PI3Kα/δ with IC50 of …
Formula:
C25H35N7O9S4
Purity:
99.63%
Color and Shape:
Solid
Molecular weight:
705.85
Ref: TM-T11381
| 10mg | 35.00 € | ||
| 25mg | 47.00 € | ||
| 50mg | 54.00 € | ||
| 1mL*10mM (DMSO) | 39.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Tenalisib
CAS:1639417-53-0
Tenalisib (RP6530) (RP6530) is a potent and selective inhibitor of PI3Kδ and PI3Kγ(IC50 values of …
Formula:
C23H18FN5O2
Purity:
99.71%
Color and Shape:
Solid
Molecular weight:
415.42
Ref: TM-T13119
| 1mg | 38.00 € | ||
| 2mg | 49.00 € | ||
| 5mg | 80.00 € | ||
| 10mg | 110.00 € | ||
| 25mg | 185.00 € | ||
| 50mg | 299.00 € | ||
| 100mg | 449.00 € | ||
| 1mL*10mM (DMSO) | 89.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
NSC781406
CAS:1676893-24-5
NSC781406 is a highly effective inhibitor of PI3K and mTOR (IC50: 2 nM for PI3Kα).
Formula:
C29H27F2N5O5S2
Purity:
99.58%
Color and Shape:
Solid
Molecular weight:
627.68
Ref: TM-T16355
| 2mg | 41.00 € | ||
| 5mg | 62.00 € | ||
| 10mg | 90.00 € | ||
| 25mg | 164.00 € | ||
| 50mg | 238.00 € | ||
| 100mg | 365.00 € | ||
| 200mg | 520.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
BAY1082439
CAS:1375469-38-7
BAY1082439, an orally bioavailable, selective inhibitor of PI3Kα/β/δ, demonstrates high efficacy in inhibiting the growth …
Formula:
C25H30N6O5
Purity:
100%
Color and Shape:
Solid
Molecular weight:
494.54
Ref: TM-T14511
| 1mg | 37.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 118.00 € | ||
| 25mg | 184.00 € | ||
| 50mg | 343.00 € | ||
| 100mg | 510.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Thioridazine hydrochloride
CAS:130-61-0
Thioridazine hydrochloride (Mellaril) , an antipsychotic drug, is used in the therapy of psychosis and …
Formula:
C21H27ClN2S2
Purity:
99.55% - 99.55%
Color and Shape:
White To Off-White Solid
Molecular weight:
407.04
Ref: TM-T0365
| 50mg | 47.00 € | ||
| 100mg | 52.00 € | ||
| 200mg | 64.00 € | ||
| 500mg | 87.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
CGS 15943
CAS:104615-18-1
CGS 15943 is an orally bioavailable non-xanthine antagonist of Adenosine Receptor.
Formula:
C13H8ClN5O
Purity:
99.63%
Color and Shape:
Solid
Molecular weight:
285.69
Ref: TM-T14944
| 1mg | 46.00 € | ||
| 5mg | 88.00 € | ||
| 10mg | 128.00 € | ||
| 25mg | 207.00 € | ||
| 50mg | 310.00 € | ||
| 100mg | 463.00 € | ||
| 1mL*10mM (DMSO) | 91.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Isoprenaline hydrochloride
CAS:51-30-9
Isoprenaline hydrochloride (NCI-c55630) is a potent beta-adrenergic agonist with the peripheral vasodilator, bronchodilator, and cardiac …
Formula:
C11H18ClNO3
Purity:
100% - 98%
Color and Shape:
Turn Brownish-Pink Upon Prolonged Exposure To Air (Ntp 1992)
Molecular weight:
247.719
Ref: TM-T1056
| 1g | 44.00 € | ||
| 1mL*10mM (DMSO) | 36.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Copanlisib dihydrochloride
CAS:1402152-13-9
Copanlisib dihydrochloride: ATP-competitive PI3K inhibitor, potent for PI3Kα/δ/β/γ, antitumor, 2000x selectivity over other kinases except …
Formula:
C23H30Cl2N8O4
Purity:
99.05%
Color and Shape:
Solid
Molecular weight:
553.44
Ref: TM-T14998
| 5mg | 51.00 € | ||
| 10mg | 78.00 € | ||
| 25mg | 123.00 € | ||
| 50mg | 207.00 € | ||
| 100mg | 346.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Recilisib
CAS:334969-03-8
Recilisib (ON 01210) is a radioprotectant,can activate AKT, PI3K activities in cells.
Formula:
C16H13ClO4S
Purity:
98.85% - 99.84%
Color and Shape:
Solid
Molecular weight:
336.79
Ref: TM-T13862
| 1mg | 45.00 € | ||
| 2mg | 58.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 118.00 € | ||
| 25mg | 183.00 € | ||
| 50mg | 348.00 € | ||
| 100mg | 520.00 € | ||
| 500mg | 1,140.00 € | ||
| 1mL*10mM (DMSO) | 105.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Parsaclisib
CAS:1426698-88-5
Parsaclisib (INCB050465) is a potent and selective inhibitor of PI3Kδ(IC50 of 1 nM at 1 …
Formula:
C20H22ClFN6O2
Purity:
98.59%
Color and Shape:
Solid
Molecular weight:
432.88
Ref: TM-T12367
| 1mg | 143.00 € | ||
| 5mg | 299.00 € | ||
| 10mg | 485.00 € | ||
| 25mg | 788.00 € | ||
| 50mg | 1,087.00 € | ||
| 100mg | 1,473.00 € | ||
| 1mL*10mM (DMSO) | 334.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
IPI-3063
CAS:1425043-73-7
IPI-3063 is an effective and selective inhibitor of PI3K p110δ (IC50: 2.5 ± 1.2 nM).
Formula:
C25H25N7O2
Purity:
99.08%
Color and Shape:
Solid
Molecular weight:
455.51
Ref: TM-T15592
| 1mg | 46.00 € | ||
| 2mg | 63.00 € | ||
| 5mg | 102.00 € | ||
| 10mg | 171.00 € | ||
| 25mg | 333.00 € | ||
| 50mg | 462.00 € | ||
| 100mg | 630.00 € | ||
| 1mL*10mM (DMSO) | 113.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Safingol hydrochloride
CAS:139755-79-6
Safingol hydrochloride (L-threo-dihydrosphingosine hydrochloride) is a PKC-specific inhibitor that inhibits PKC and PI3k and induces …
Formula:
C18H40ClNO2
Purity:
99.31% - 99.71%
Color and Shape:
Soild
Molecular weight:
337.969
Ref: TM-T83978
| 1mg | 184.00 € | ||
| 5mg | 455.00 € | ||
| 10mg | 651.00 € | ||
| 25mg | 1,016.00 € | ||
| 50mg | 1,401.00 € | ||
| 100mg | 1,834.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
PI3K-IN-46
CAS:304645-61-2
PI3K-IN-46 is a specific inhibitor of PI3Kγ.
Formula:
C13H9N3OS
Purity:
97.51%
Color and Shape:
Soild
Molecular weight:
255.3
Ref: TM-T64392
| 1mg | 112.00 € | ||
| 5mg | 249.00 € | ||
| 10mg | 365.00 € | ||
| 25mg | 547.00 € | ||
| 50mg | 770.00 € | ||
| 100mg | 1,035.00 € | ||
| 200mg | 1,404.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
PI3Kα-IN-12
PI3Kα-IN-12 (compound 13), a potent and selective PI3Kα inhibitor (IC50: 1.2 nM), effectively suppresses HCT-116 …
Formula:
C28H36F2N10O5S3
Color and Shape:
Liquid
Molecular weight:
726.84
Ref: TM-T78804
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 5 Dec 2024
hSMG-1 inhibitor 11j
CAS:1402452-15-6
hSMG-1 inhibitor 11j: pyrimidine, IC50=0.11 nM, >455x selective vs. mTOR/PI3Kα/γ/CDK1/CDK2; cancer research use.
Formula:
C27H28ClN7O3S
Purity:
99.04% - 99.29%
Color and Shape:
Solid
Molecular weight:
566.07
Ref: TM-T8884
| 1mg | 158.00 € | ||
| 2mg | 227.00 € | ||
| 5mg | 385.00 € | ||
| 10mg | 574.00 € | ||
| 25mg | 921.00 € | ||
| 50mg | 1,243.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
