MELK
MELK inhibitors are compounds that inhibit Maternal Embryonic Leucine Zipper Kinase (MELK), an enzyme implicated in the regulation of cell proliferation, apoptosis, and the cell cycle. MELK is often overexpressed in various cancers, and its inhibition is being explored as a potential therapeutic strategy in oncology. Inhibiting MELK can help to better understand its role in cancer progression and to develop new cancer treatments. At CymitQuimica, we offer MELK inhibitors to support your research in cancer biology, cell cycle regulation, and therapeutic discovery.
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MELK-IN-1
CAS:2095596-44-2
MELK-IN-1 (MELK inhibitor 17) is a potent inhibitor of maternal embryonic leucine zipper kinase (MELK),(IC50:3nm;Ki:0.39 …
Formula:
C31H33N5O4
Purity:
99.14%
Color and Shape:
Solid
Molecular weight:
539.62
Ref: TM-T11997
| 1mg | 36.00 € | ||
| 5mg | 70.00 € | ||
| 10mg | 103.00 € | ||
| 25mg | 200.00 € | ||
| 50mg | 326.00 € | ||
| 100mg | 534.00 € | ||
| 1mL*10mM (DMSO) | 84.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Antitumor agent-116
Antitumor Agent-116 (Compound 6C) is an anti-tumor agent that exhibits anti-proliferative properties and induces apoptosis.
Formula:
C31H23BrN4O4S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
627.51
Ref: TM-T79582
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 5 Dec 2024
MELK-8a Dihydrochloride
MELK-8a Dihydrochloride is a useful organic compound for research related to life sciences and the …
Purity:
98%
Color and Shape:
Liquid
Ref: TM-T35342
| 5mg | 473.00 € | ||
| 25mg | 1,432.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
OTSSP167
CAS:1431697-89-0
OTSSP167 (OTS167) is an orally available inhibitor of maternal embryonic leucine zipper kinase (MELK) with …
Formula:
C25H28Cl2N4O2
Purity:
98.22% - 99.47%
Color and Shape:
Solid
Molecular weight:
487.42
Ref: TM-T1759
| 1mg | 40.00 € | ||
| 2mg | 51.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 118.00 € | ||
| 25mg | 183.00 € | ||
| 50mg | 276.00 € | ||
| 100mg | 425.00 € | ||
| 500mg | 922.00 € | ||
| 1mL*10mM (DMSO) | 95.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Prexasertib dihydrochloride
CAS:1234015-54-3
Prexasertib dihydrochloride (LY2606368) inhibits CHK1 (Ki: 0.9 nM); IC50: CHK2 8 nM, RSK 9 nM.
Formula:
C18H21Cl2N7O2
Purity:
97.5% - 99.82%
Color and Shape:
Solid
Molecular weight:
438.31
Ref: TM-T4327
| 1mg | 45.00 € | ||
| 2mg | 58.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 142.00 € | ||
| 25mg | 269.00 € | ||
| 50mg | 418.00 € | ||
| 100mg | 616.00 € | ||
| 500mg | 1,299.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
OTSSP167 hydrochloride
CAS:1431698-10-0
OTSSP167 hydrochloride is a highly potent inhibitor of MELK(IC50 : 0.41 nM).
Formula:
C25H29Cl3N4O2
Purity:
99.97%
Color and Shape:
Solid
Molecular weight:
523.88
Ref: TM-T21559
| 1mg | 40.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 119.00 € | ||
| 25mg | 186.00 € | ||
| 50mg | 349.00 € | ||
| 100mg | 522.00 € | ||
| 1mL*10mM (DMSO) | 91.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Prexasertib
CAS:1234015-52-1
Prexasertib (LY2606368) is an inhibitor of checkpoint kinase 1 (chk1) with potential antineoplastic activity.
Formula:
C18H19N7O2
Purity:
100% - 97.3%
Color and Shape:
Solid
Molecular weight:
365.39
Ref: TM-T4310
| 1mg | 52.00 € | ||
| 2mg | 80.00 € | ||
| 5mg | 119.00 € | ||
| 10mg | 179.00 € | ||
| 25mg | 350.00 € | ||
| 50mg | 513.00 € | ||
| 100mg | 731.00 € | ||
| 500mg | 1,476.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
MELK-8a hydrochloride
CAS:2096992-20-8
MELK-8a hydrochloride is a potent inhibitor of maternal embryonic leucine zipper kinase (MELK, IC50 = …
Formula:
C25H33ClN6O
Purity:
99.87%
Color and Shape:
Solid
Molecular weight:
469.02
Ref: TM-T11996
| 1mg | 42.00 € | ||
| 2mg | 55.00 € | ||
| 5mg | 89.00 € | ||
| 10mg | 126.00 € | ||
| 25mg | 248.00 € | ||
| 50mg | 396.00 € | ||
| 100mg | 584.00 € | ||
| 500mg | 1,207.00 € | ||
| 1mL*10mM (DMSO) | 91.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
JTV-519 hemifumarate
CAS:1435938-25-2
JTV-519 hemifumarate: Ca2+ blocker, SERCA inhibitor, ryanodine receptor partial agonist; antiarrhythmic, cardioprotective.
Formula:
C54H68N4O8S2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
965.28
Ref: TM-T11732
| 25mg | To inquire | ||
| 50mg | To inquire | ||
| 100mg | To inquire |
Estimated delivery in United States, on Wednesday 22 Jan 2025
