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MELK

MELK

MELK inhibitors are compounds that inhibit Maternal Embryonic Leucine Zipper Kinase (MELK), an enzyme implicated in the regulation of cell proliferation, apoptosis, and the cell cycle. MELK is often overexpressed in various cancers, and its inhibition is being explored as a potential therapeutic strategy in oncology. Inhibiting MELK can help to better understand its role in cancer progression and to develop new cancer treatments. At CymitQuimica, we offer MELK inhibitors to support your research in cancer biology, cell cycle regulation, and therapeutic discovery.

Found 7 products of "MELK"

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  • MELK-IN-1
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    MELK-IN-1

    CAS:
    <p>MELK-IN-1 (MELK inhibitor 17) is a potent inhibitor of maternal embryonic leucine zipper kinase (MELK),(IC50:3nm;Ki:0.39 nM).</p>
    Formula:C31H33N5O4
    Purity:99.84%
    Color and Shape:Solid
    Molecular weight:539.62

    Ref: TM-T11997

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    MELK-8a Dihydrochloride

    <p>MELK-8a Dihydrochloride is a useful organic compound for research related to life sciences and the catalog number is T35342.</p>
    Purity:98%
    Color and Shape:Solid

    Ref: TM-T35342

  • Prexasertib
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    Prexasertib

    CAS:
    <p>Prexasertib (LY2606368) is a selective checkpoint kinase 1 (CHK1) inhibitor (Ki 0.9 nM, IC50&lt;1 nM). antitumor activity. High-Quality, Low-Cost!</p>
    Formula:C18H19N7O2
    Purity:97.3% - 98.23%
    Color and Shape:Solid
    Molecular weight:365.39

    Ref: TM-T4310

  • OTSSP167
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    OTSSP167

    CAS:
    <p>OTSSP167 (OTS167) is an orally available inhibitor of maternal embryonic leucine zipper kinase (MELK) with potential antineoplastic activity.</p>
    Formula:C25H28Cl2N4O2
    Purity:98.22% - 99.47%
    Color and Shape:Solid
    Molecular weight:487.42

    Ref: TM-T1759

  • Prexasertib dihydrochloride
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    Prexasertib dihydrochloride

    CAS:
    <p>Prexasertib dihydrochloride (LY2606368) inhibits CHK1 (Ki: 0.9 nM); IC50: CHK2 8 nM, RSK 9 nM.</p>
    Formula:C18H21Cl2N7O2
    Purity:98.46% - 99.82%
    Color and Shape:Solid
    Molecular weight:438.31

    Ref: TM-T4327

  • OTSSP167 hydrochloride
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    OTSSP167 hydrochloride

    CAS:
    <p>OTSSP167 hydrochloride is a highly potent inhibitor of MELK(IC50 : 0.41 nM).</p>
    Formula:C25H29Cl3N4O2
    Purity:99.41%
    Color and Shape:Solid
    Molecular weight:523.88

    Ref: TM-T21559

  • MELK-8a hydrochloride
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    MELK-8a hydrochloride

    CAS:
    <p>MELK-8a hydrochloride is a potent inhibitor of maternal embryonic leucine zipper kinase (MELK, IC50 = 2 nM). </p>
    Formula:C25H33ClN6O
    Purity:99.87%
    Color and Shape:Solid
    Molecular weight:469.02

    Ref: TM-T11996