mTOR
mTOR inhibitors are compounds that inhibit the activity of Mammalian Target of Rapamycin (mTOR), a central regulator of cell growth, proliferation, metabolism, and survival. The mTOR pathway is frequently altered in cancer and other diseases, making mTOR a critical target for therapeutic intervention. Inhibitors of mTOR are widely used in research related to cancer, aging, and metabolic disorders. At CymitQuimica, we offer a variety of mTOR inhibitors to support your research in signal transduction, oncology, and therapeutic development.
Found 163 products of "mTOR"
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NSC781406
CAS:NSC781406 is a highly effective inhibitor of PI3K and mTOR (IC50: 2 nM for PI3Kα).Formula:C29H27F2N5O5S2Purity:99.58%Color and Shape:SolidMolecular weight:627.68Ref: TM-T16355
2mg39.00€5mg60.00€10mg87.00€25mg159.00€50mg231.00€100mg355.00€200mg505.00€1mL*10mM (DMSO)84.00€Thioridazine hydrochloride
CAS:Thioridazine hydrochloride (Mellaril) , an antipsychotic drug, is used in the therapy of psychosis and schizophrenia and shows serotonin antagonism or D4Formula:C21H27ClN2S2Purity:99.55% - 99.957%Color and Shape:White To Off-White SolidMolecular weight:407.04SN32976
CAS:SN32976 is a pan PI3K inhibitor. SN32976 potently inhibited PI3K isoforms and mTOR, displaying preferential activity for PI3Kα and sparing of PI3Kδ.Formula:C24H33F2N9O4SPurity:98.06%Color and Shape:SolidMolecular weight:581.64Rapamycin
CAS:Rapamycin, a macrolide from Streptomyces hygroscopicus, inhibits mTOR (IC50: 0.1 nM) and promotes autophagy with immunosuppressive effects.Formula:C51H79NO13Purity:97.08% - 99.80%Color and Shape:Yellow SolidMolecular weight:914.17Ref: TM-T1537
1g268.00€10mg34.00€25mg46.00€50mg50.00€100mg65.00€200mg101.00€500mg178.00€1mL*10mM (DMSO)48.00€MT 63-78
CAS:MT 63-78 is a specific and effective direct AMPK activator (EC50: 25 μM).
Formula:C21H14N2O2Purity:97.11%Color and Shape:SolidMolecular weight:326.35NV-5138
CAS:NV-5138 is a selective and orally active activator of brain mTORC1, with antidepressant effects.Cost-effective and quality-assured.Formula:C7H13F2NO2Purity:98% - ≥98%Color and Shape:SolidMolecular weight:181.18Ref: TM-T12270
1mg89.00€5mg215.00€10mg344.00€25mg737.00€50mg1,169.00€100mg1,691.00€1mL*10mM (DMSO)170.00€DEPTOR-IN-1
CAS:DEPTOR-IN-1 is an inhibitor of DEPTOR with a Kd of 9.3 μM.Formula:C24H16Cl2FNO4Purity:97.84%Color and Shape:SolidMolecular weight:472.29PI3K-IN-22
CAS:PI3K-IN-22 is a dual kinase inhibitor of PI3Kα and mTOR, with IC50s of 0.9 and 0.6 nM respectively. PI3K-IN-22 could be used in cancer.Formula:C31H35F3N8O3Color and Shape:SolidMolecular weight:624.66PF-06465603
CAS:PF-06465603 is a metabolite of PF-04691502, a highly potent and selective ATP competitive kinase inhibitor of class 1 PI3Ks and mTOR.Formula:C22H25N5O5Color and Shape:SolidMolecular weight:439.46MKC-1
CAS:MKC-1 (Ro-31-7453) is an oral bisindolylmaleimide inhibitor that disrupts tubulin polymerization, potentially halting cancer cell division.Formula:C22H16N4O4Purity:99.63% - 99.85%Color and Shape:SolidMolecular weight:400.39Ref: TM-T9831
1mg54.00€5mg118.00€10mg168.00€25mg293.00€50mg423.00€100mg588.00€500mgTo inquire1mL*10mM (DMSO)127.00€mTOR inhibitor-12
mTOR inhibitor-12 (Compound 11), a selective, brain-penetrant mTOR inhibitor, exhibits no genotoxicity risk and is utilized in research pertaining to centralFormula:C19H24N6O2SPurity:98%Color and Shape:SolidMolecular weight:400.5RMC-4529
CAS:RMC-4529 is a chemical compound that demonstrates potent inhibition, with an IC50 value of 1.0 nM, against p-4E-BP1-(T37/46) in mTOR kinase cellular assays.Formula:C90H139N13O23Color and Shape:SolidMolecular weight:1771.17RMC-6272
CAS:RMC-6272 (RM-006) is a bi-steric mTORC1 inhibitor with selective potency over mTORC2 and shows greater effects than Rapamycin on TSC2-deficient tumors.Formula:C95H141FN6O27SColor and Shape:SolidMolecular weight:1850.25PI3K-AKT-mTOR Compound Library
A unique collection of 420 compounds targeting PI3K/Akt/mTOR signaling for research in PI3K/Akt/mTOR signaling, and drug discovery in diseases involved withColor and Shape:Odour SolidRef: TM-L1300
1mgTo inquire30μL*10mM (DMSO)To inquire50μL*10mM (DMSO)To inquire100μL*10mM (DMSO)To inquire250μL*10mM (DMSO)To inquireYB-3-17
CAS:YB-3-17 is a bifunctional molecule that can inhibit mTOR with an IC50 of 0.22 nM or degrade the G1 to S phase transition 1 gene (GSPT1) through the PROTAC mechanism, with a DC50 of 5 nM. It exhibits antiproliferative activity at nanomolar concentrations in various glioblastoma cell lines. Additionally, YB-3-17 shows antitumor activity in mouse models. (Pink: ligand for target protein; Black: linker; Blue: ligand for E3 ligase Cereblon)Formula:C38H39N11O6Color and Shape:SolidMolecular weight:745.786FD274
CAS:FD274 is a potent dual PI3K/mTOR inhibitor with inhibitory effects on PI3Kα/β/γ/δ and mTOR, with IC50s of 0.65 nM, 1.57 nM, 0.65 nM, 0.42 nM, and 2.03 nM,Formula:C22H14ClFN6O2SPurity:98%Color and Shape:SoildMolecular weight:480.9FDA-Approved Kinase Inhibitor Library
A unique collection of 263 kinase inhibitors/regulators for specific targeting of kinases, ready for high-throughput screening and high-content screening.
Color and Shape:LiquidmTOR inhibitor 13
CAS:Urea derivative; selective mTOR blocker; IC50: 0.29nM (mTOR), 119nM (PI3Kα).Formula:C24H22N6O2SPurity:99.75%Color and Shape:SolidMolecular weight:458.54RMC-4627
CAS:RMC-4627 is a selective mTORC1 inhibitor that activates 4EBP1 and inhibits tumor growth.Formula:C93H141N11O23Color and Shape:SolidMolecular weight:1781.17Thioether-cyclized helix B peptide, CHBP TFA
Thioether-cyclized helix B peptide, CHBP (TFA), is the trifluoroacetic (TFA) salt of CHBP.Formula:C56H93N19O22S·xC2HF3O2Purity:98%Color and Shape:SolidMolecular weight:1416.52 (free base)mTOR inhibitor 9c
CAS:mTOR inhibitor 9c is a selective mTOR inhibitor with IC50 of 0.7nM and 825nM for mTOR and PI3Kα, respectively.Formula:C21H22FN5O2SPurity:99.23%Color and Shape:SoildMolecular weight:427.5(32-Carbonyl)-RMC-5552
CAS:(32-Carbonyl)-RMC-5552, a potent mTOR inhibitor, blocks mTORC1/C2, with pIC50 values >9 for p-P70S6K and p-4E-BP1, and 8~9 for p-AKT1/2/3.Formula:C93H134N10O24Color and Shape:SolidMolecular weight:1776.141Thioether-cyclized helix B peptide, CHBP
CAS:Thioether-cyclized helix B peptide (CHBP) enhances metabolic stability and exerts renoprotective effects by promoting autophagy through the inhibition of mTORFormula:C56H93N19O22SPurity:98%Color and Shape:SolidMolecular weight:1416.52mTOR inhibitor-14
mTOR Inhibitor-14 (compound 14c) is a potent inhibitor of mTOR with minimal inhibition of CYP2C8 and has demonstrated the capability to inhibit tumor growth [1Purity:98%Color and Shape:Odour SolidmTOR inhibitor WYE-28
CAS:mTOR inhibitor WYE-28, Potent mTOR (IC50=0.08 nM) and PI3Kα (IC50=6 nM) inhibitor, short half-life in mouse microsomes.Formula:C30H34N8O5Color and Shape:SolidMolecular weight:586.65AJ2-30
CAS:AJ2-30: Inhibits SLCl5A4, TLR9-B cell activation, MDP transport, NOD signaling; for inflammation study.Formula:C23H22N4Purity:>99.99%Color and Shape:SoildMolecular weight:354.45Ref: TM-T77644
1mg48.00€5mg101.00€10mg167.00€25mg334.00€50mg537.00€100mg762.00€200mg1,018.00€1mL*10mM (DMSO)114.00€QL-IX-55
CAS:QL-IX-55 has a wide range of applications in life science related research.Formula:C24H14F4N4OColor and Shape:SolidMolecular weight:450.39mTOR inhibitor 9e
CAS:mTOR inhibitor 9e is a selective mTOR inhibitor with IC50 of 0.68nM and 1359nM for mTOR and PI3Kα, respectively.Formula:C22H23N5O2SPurity:98.84%Color and Shape:SoildMolecular weight:421.52WYE-687
CAS:WYE-687 is a selective mTOR inhibitor (IC50: 7 nM), over 100x more selective for mTOR than PI3Kα/γ, affecting mTORC1/pS6K and mTORC2/P-AKT(S473).Formula:C28H32N8O3Purity:99.93%Color and Shape:SolidMolecular weight:528.61DA-143
DA-143 is a selective inhibitor of DNA-PKcs (IC50: 2.5 nM), demonstrating disparate inhibitory effects on mTOR, PI3KΔ, and ATM, with IC50 values of 280 nM, 106 nM, and 6,594 nM, respectively. This compound effectively blocks the phosphorylation of DNA-PKcs substrates and enhances the sensitivity of cancer cells to doxorubicin.Color and Shape:Odour SolidKinase Inhibitor Library
A unique collection of 2720 kinase inhibitors/regulators for high throughput screening and high content screening for drug discovery in kinase related diseases;Color and Shape:Odour SolidRef: TM-L1600
1mgTo inquire30μL*10mM (DMSO)To inquire50μL*10mM (DMSO)To inquire100μL*10mM (DMSO)To inquire250μL*10mM (DMSO)To inquireAschantin
CAS:Aschantin is a useful organic compound for research related to life sciences. The catalog number is T126072 and the CAS number is 13060-15-6.Formula:C22H24O7Color and Shape:SolidMolecular weight:400.427MCX 28
CAS:MCX 28, a triple PI3K/mTOR/PIM inhibitor, displays low nanomolar activity.Formula:C25H19N5O4S3Color and Shape:SolidMolecular weight:549.642DII
2DII is a potent and selective mTORC2 inhibitor. It specifically binds to the mSin1 PH domain, resulting in a decreased phosphorylation of AKT1.Formula:C54H76ClN7O11SColor and Shape:SolidMolecular weight:1066.74mTOR inhibitor 9f
CAS:mTOR inhibitor 9f is a selective mTOR inhibitor with IC50 of 1.25nM and 82nM for mTOR and PI3Kα, respectively.Formula:C25H23N5O2SPurity:99.18%Color and Shape:SoildMolecular weight:457.55RMC-5552
CAS:RMC-5552 selectively inhibits mTORC1 with ~40-fold selectivity over mTORC2, demonstrating anticancer activity and research utility.Formula:C93H136N10O24Color and Shape:SolidMolecular weight:1778.16Cbz-B3A
CAS:Cbz-B3A is a potent inhibitor of mTORC1 signalling, inhibits phosphorylation of eIF4E-binding protein 1 (4EBP1) and blocks translation by 68%.Formula:C35H58N6O9Purity:98.59%Color and Shape:SolidMolecular weight:706.87Anti-Phospho-MTOR (Ser2448) Antibody (2K503)
Anti-Phospho-MTOR (Ser2448) Antibody (2K503) is an antibody targeting Phospho-MTOR (Ser2448). Anti-Phospho-MTOR (Ser2448) Antibody (2K503) can be used in ELISA, WB, IHC, IF.Color and Shape:Odour LiquidAnti-Phospho-mTOR (Ser2481) Antibody (4R8)
Anti-Phospho-MTOR (Ser2481) Antibody (4R8) is an antibody targeting Phospho-MTOR (Ser2481). Anti-Phospho-MTOR (Ser2481) Antibody (4R8) can be used in ELISA, WB, IF.Color and Shape:Odour LiquidS6K1-IN-DG2
CAS:S6K1-IN-DG2(S6K1InhibitorDG2) is a potent p70S6K inhibitor with an IC50 value of less than 100 nM.Formula:C16H17BrN6OPurity:99.99%Color and Shape:SolidMolecular weight:389.25Omipalisib
CAS:Omipalisib (GSK2126458) is a small-molecule pyridylsulfonamide inhibitor of phosphatidylinositol 3-kinase (PI3K) with potential antineoplastic activity.Formula:C25H17F2N5O3SPurity:98% - 99.8%Color and Shape:SolidMolecular weight:505.5Lupiwighteone
CAS:Lupiwighteone has anti-angiogenesis potential, it also has anticancer and cancer preventive effects on SH-SY5Y cells.Formula:C20H18O5Purity:98.92%Color and Shape:SolidMolecular weight:338.35Samotolisib
CAS:Samotolisib (LY3023414) inhibits PI3K, DNA-PK, mTOR; tested for solid tumors including breast and colon cancer.Formula:C23H26N4O3Purity:98.41% - 99.69%Color and Shape:SolidMolecular weight:406.48mTOR inhibitor-1
CAS:C-4 is a potential ATP-competitive inhibitor of mTOR. C-4 could inhibit cell growth and proliferation.Formula:C16H15BrN2O3Purity:99.43%Color and Shape:SolidMolecular weight:363.21Mito-LND
CAS:Mito-LND (Mito-Loidamine) is an orally active and mitochondria-targeted inhibitor of oxidative phosphorylation.Formula:C43H45BrCl2N3OPPurity:97.25% - 98.34%Color and Shape:SolidMolecular weight:801.62PF-04691502
CAS:PF-04691502 is a potent and selective inhibitor of PI3K and mTOR kinases with antitumor activity.Formula:C22H27N5O4Purity:96.27% - ≥95%Color and Shape:SolidMolecular weight:425.48Ref: TM-T6251
1mg34.00€2mg43.00€5mg63.00€10mg88.00€25mg117.00€50mg187.00€100mg333.00€1mL*10mM (DMSO)65.00€Corynoxine
CAS:Corynoxine is a tetracyclic oxindole alkaloid isolated from Uncaria macrophylla.Formula:C22H28N2O4Purity:96.83% - 99.93%Color and Shape:SolidMolecular weight:384.47Salidroside
CAS:Salidroside is a bioactive phenolic glycoside compound isolated from Rhodiola rosea and is a prolyl endopeptidase inhibitor.Cost-effective and quality-assured.Formula:C14H20O7Purity:97.81%Color and Shape:Red-Brown Fine PowderMolecular weight:300.30Ref: TM-T2717
2mg34.00€5mg50.00€10mg81.00€25mg130.00€50mg178.00€100mg268.00€200mg408.00€1mL*10mM (DMSO)55.00€OSI-027
CAS:OSI-027 (ASP4786) is a selective and potent dual inhibitor of mTORC1 and mTORC2 with IC50 of 22 nM and 65 nM.Formula:C21H22N6O3Purity:97.42%Color and Shape:SolidMolecular weight:406.44Ref: TM-T6319
1mg39.00€2mg50.00€5mg81.00€10mg131.00€25mg235.00€50mg369.00€100mg537.00€1mL*10mM (DMSO)84.00€
