mTOR
mTOR inhibitors are compounds that inhibit the activity of Mammalian Target of Rapamycin (mTOR), a central regulator of cell growth, proliferation, metabolism, and survival. The mTOR pathway is frequently altered in cancer and other diseases, making mTOR a critical target for therapeutic intervention. Inhibitors of mTOR are widely used in research related to cancer, aging, and metabolic disorders. At CymitQuimica, we offer a variety of mTOR inhibitors to support your research in signal transduction, oncology, and therapeutic development.
Found 164 products for "mTOR".
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GNE-490
CAS:GNE-490 is an effective inhibitor of pan-PI3K with IC50s of 3.5 nM, 25 nM, 5.2 nM, 15 nM for PI3Kα, PI3Kβ, PI3Kδ and PI3Kγ, respectively.Formula:C18H22N6O2SPurity:99.77%Color and Shape:White SolidMolecular weight:386.47Ref: TM-T22339
1mg80.00€2mg109.00€5mg178.00€1mL*10mM (DMSO)193.00€10mg304.00€25mg482.00€50mg665.00€100mg883.00€200mg1,215.00€WYE-132
CAS:WYE-125132: potent mTOR inhibitor, IC50 0.19 nM, selective over PI3Ks/hSMG1/ATR.Formula:C27H33N7O4Purity:99.29%Color and Shape:SolidMolecular weight:519.6mTOR inhibitor-11
CAS:mTOR inhibitor-11 (Compound 9) is a brain-penetrant compound capable of inhibiting mTOR with an IC50 of 21 nM for pS6.Formula:C21H26N6O2Purity:98%Color and Shape:SolidMolecular weight:394.47mTOR inhibitor 9d
CAS:mTOR inhibitor 9d is a dual inhibitor of the protein kinases mTOR and PI3K with an mTOR IC50 value of 0.31 nm, and can be used for the treatment of leukemia,Formula:C21H23N5O3SPurity:98.91%Color and Shape:SolidMolecular weight:425.5WYE-23
CAS:WYE-23 is an inhibitor of mammalian target of rapamycin (mTOR).Formula:C26H32N8O4Color and Shape:SolidMolecular weight:520.58PI3K/mTOR Inhibitor-12
CAS:PI3K/mTOR Inhibitor-12: oral, potent, selective; IC50: PI3Kα 0.06 nM, mTOR 3.12 nM; strong antitumor; less liver toxicity.Formula:C27H27F2N9O4SPurity:98%Color and Shape:SolidMolecular weight:611.62Rheb inhibitor NR1
CAS:Rheb inhibitor NR1 is a Rheb inhibitor and selective mTORC1 inhibitor that promotes phosphorylation of S473pAKT.Formula:C25H19BrCl2N2O3SPurity:99.72%Color and Shape:White SolidMolecular weight:578.3Ref: TM-T16741
1mL*10mM (DMSO)44.00€1mg87.00€5mg178.00€10mg295.00€25mg595.00€50mg895.00€100mg1,513.00€WAY-600
CAS:WAY-600 is a potent, ATP-competitive and selective inhibitor of mTOR with IC50 of 9 nM; blocks mTORC1/P-S6K(T389) and mTORC2/P-AKT(S473) but not P-AKT(T308).Formula:C28H30N8OPurity:99.88%Color and Shape:SolidMolecular weight:494.59GDC-0349
CAS:GDC-0349 (RG-7603) is a potent and selective ATP-competitive inhibitor of mTOR, 790-fold inhibitory effect against PI3Kα and other 266 kinases. Phase 1.Formula:C24H32N6O3Purity:96.00% - 98.49%Color and Shape:SolidMolecular weight:452.55PKI-402
CAS:PKI-402 is a potent PI3K and mTOR inhibitor. PKI-402 inhibits PI3Kα, mTOR, PI3Kβ, PI3Kδ and PI3Kγ with IC50s of 2, 3, 7, 14 and 16 nM, respectively.Formula:C29H34N10O3Purity:99.94%Color and Shape:SolidMolecular weight:570.65PF-04979064
CAS:PF-04979064 is a potent and selective PI3K and mTOR dual kinase inhibitor(Ki of 0.13 nM and 1.42 nM,respectively).Formula:C24H26N6O3Purity:99.98% - ≥98%Color and Shape:SolidMolecular weight:446.5PD-M6
CAS:PD-M6 is an mTOR PROTAC degrader with a DC50 of 4.8 μM, which facilitates the ubiquitination and degradation of mTOR. It inhibits the proliferation of cancer cell lines HeLa, MCF-7, and HepG2 with IC50 values of 11.3, 2.58, and 3.23 μM, respectively, and induces autophagy. Additionally, PD-M6 specifically targets the degradation of the key protein LAMTOR1 in the mTOR signaling pathway.Formula:C30H39N9O6Color and Shape:SolidMolecular weight:621.69PI3K-IN-37
CAS:PI3K-IN-37 inhibits PI3K α/β/δ (IC50: 6/8/4 nM) and mTOR (IC50: 4 nM).Formula:C25H26N6O2Color and Shape:SolidMolecular weight:442.51AZD 3147
CAS:AZD 3147 inhibits mTORC1 (40.7 nM), mTORC2 (5.75 nM), and PI3Kα/β/δ/γ (912/5495/9333/6310 nM IC50s).Formula:C24H31N5O4S2Purity:99.99%Color and Shape:SolidMolecular weight:517.66Ref: TM-T36200
1mg92.00€5mg200.00€1mL*10mM (DMSO)259.00€10mg319.00€25mg550.00€50mg737.00€100mg1,018.00€
