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mTOR

mTOR

mTOR inhibitors are compounds that inhibit the activity of Mammalian Target of Rapamycin (mTOR), a central regulator of cell growth, proliferation, metabolism, and survival. The mTOR pathway is frequently altered in cancer and other diseases, making mTOR a critical target for therapeutic intervention. Inhibitors of mTOR are widely used in research related to cancer, aging, and metabolic disorders. At CymitQuimica, we offer a variety of mTOR inhibitors to support your research in signal transduction, oncology, and therapeutic development.

Found 144 products of "mTOR"

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  • NSC781406
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    NSC781406

    CAS:
    <p>NSC781406 is a highly effective inhibitor of PI3K and mTOR (IC50: 2 nM for PI3Kα).</p>
    Formula:C29H27F2N5O5S2
    Purity:99.58%
    Color and Shape:Solid
    Molecular weight:627.68

    Ref: TM-T16355

  • NV-5138
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    NV-5138

    CAS:
    <p>NV-5138 is a selective and orally active activator of brain mTORC1, with antidepressant effects.Cost-effective and quality-assured.</p>
    Formula:C7H13F2NO2
    Purity:98% - ≥98%
    Color and Shape:Solid
    Molecular weight:181.18

    Ref: TM-T12270

  • Thioridazine hydrochloride
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    Thioridazine hydrochloride

    CAS:
    <p>Thioridazine hydrochloride (Mellaril) , an antipsychotic drug, is used in the therapy of psychosis and schizophrenia and shows serotonin antagonism or D4</p>
    Formula:C21H27ClN2S2
    Purity:99.55% - 99.957%
    Color and Shape:White To Off-White Solid
    Molecular weight:407.04

    Ref: TM-T0365

  • MT 63-78
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    MT 63-78

    CAS:
    <p>MT 63-78 is a specific and effective direct AMPK activator (EC50: 25 μM).</p>
    Formula:C21H14N2O2
    Purity:97.11%
    Color and Shape:Solid
    Molecular weight:326.35

    Ref: TM-T16156

  • ICSN3250 HCl
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    ICSN3250 HCl

    CAS:
    <p>ICSN3250 HCl is an mTOR inhibitor that specifically targets cancer cells, preventing mTOR activation and leading to cytotoxicity.</p>
    Formula:C31H41ClN4O8
    Purity:98.46% - 99.60%
    Color and Shape:Soild
    Molecular weight:633.13

    Ref: TM-T70442L

  • SN32976
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    SN32976

    CAS:
    <p>SN32976 is a pan PI3K inhibitor. SN32976 potently inhibited PI3K isoforms and mTOR, displaying preferential activity for PI3Kα and sparing of PI3Kδ.</p>
    Formula:C24H33F2N9O4S
    Purity:98.06%
    Color and Shape:Solid
    Molecular weight:581.64

    Ref: TM-T9788

  • Rapamycin
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    Rapamycin

    CAS:
    <p>Rapamycin, a macrolide from Streptomyces hygroscopicus, inhibits mTOR (IC50: 0.1 nM) and promotes autophagy with immunosuppressive effects.</p>
    Formula:C51H79NO13
    Purity:97.08% - 99.80%
    Color and Shape:Yellow Solid
    Molecular weight:914.17

    Ref: TM-T1537

  • (32-Carbonyl)-RMC-5552
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    (32-Carbonyl)-RMC-5552

    CAS:
    <p>(32-Carbonyl)-RMC-5552, a potent mTOR inhibitor, blocks mTORC1/C2, with pIC50 values &gt;9 for p-P70S6K and p-4E-BP1, and 8~9 for p-AKT1/2/3.</p>
    Formula:C93H134N10O24
    Color and Shape:Solid
    Molecular weight:1776.141

    Ref: TM-T39958

  • RMC-4529
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    RMC-4529

    CAS:
    <p>RMC-4529 is a chemical compound that demonstrates potent inhibition, with an IC50 value of 1.0 nM, against p-4E-BP1-(T37/46) in mTOR kinase cellular assays.</p>
    Formula:C90H139N13O23
    Color and Shape:Solid
    Molecular weight:1771.17

    Ref: TM-T39776

  • YB-3-17
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    YB-3-17

    CAS:
    <p>YB-3-17 is a bifunctional molecule that can inhibit mTOR with an IC50 of 0.22 nM or degrade the G1 to S phase transition 1 gene (GSPT1) through the PROTAC mechanism, with a DC50 of 5 nM. It exhibits antiproliferative activity at nanomolar concentrations in various glioblastoma cell lines. Additionally, YB-3-17 shows antitumor activity in mouse models. (Pink: ligand for target protein; Black: linker; Blue: ligand for E3 ligase Cereblon)</p>
    Formula:C38H39N11O6
    Color and Shape:Solid
    Molecular weight:745.786

    Ref: TM-T204111

  • PI3K-IN-22
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    PI3K-IN-22

    CAS:
    <p>PI3K-IN-22 is a dual kinase inhibitor of PI3Kα and mTOR, with IC50s of 0.9 and 0.6 nM respectively. PI3K-IN-22 could be used in cancer.</p>
    Formula:C31H35F3N8O3
    Color and Shape:Solid
    Molecular weight:624.66

    Ref: TM-T36087

  • mTOR inhibitor WYE-28
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    mTOR inhibitor WYE-28

    CAS:
    <p>Compound 28 (mTOR inhibitor WYE-28) is a selective inhibitor of mTOR (IC50=0.08 nM). Also inhibits PI3Kα (IC50 6 nM).</p>
    Formula:C30H34N8O5
    Color and Shape:Solid
    Molecular weight:586.653

    Ref: TM-T36307

  • PF-06465603
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    PF-06465603

    CAS:
    <p>PF-06465603 is a metabolite of PF-04691502, a highly potent and selective ATP competitive kinase inhibitor of class 1 PI3Ks and mTOR.</p>
    Formula:C22H25N5O5
    Color and Shape:Solid
    Molecular weight:439.46

    Ref: TM-T28373

  • RMC-6272
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    RMC-6272

    CAS:
    <p>RMC-6272 (RM-006) is a bi-steric mTORC1 inhibitor with selective potency over mTORC2 and shows greater effects than Rapamycin on TSC2-deficient tumors.</p>
    Formula:C95H141FN6O27S
    Color and Shape:Solid
    Molecular weight:1850.25

    Ref: TM-T39959

  • RMC-4627
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    RMC-4627

    CAS:
    <p>RMC-4627 is a selective mTORC1 inhibitor that activates 4EBP1 and inhibits tumor growth.</p>
    Formula:C93H141N11O23
    Color and Shape:Solid
    Molecular weight:1781.17

    Ref: TM-T74283

  • CymitQuimica logo
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    HN2210

    <p>Compound HN2210 (compund HN2210) is an inhibitor of mTORC2.</p>
    Color and Shape:Odour Solid

    Ref: TM-T200784

  • QL-IX-55
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    QL-IX-55

    CAS:
    <p>QL-IX-55 has a wide range of applications in life science related research.</p>
    Formula:C24H14F4N4O
    Color and Shape:Solid
    Molecular weight:450.39

    Ref: TM-T36313

  • Kinase Inhibitor Library
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    Kinase Inhibitor Library

    <p>A unique collection of 2720 kinase inhibitors/regulators for high throughput screening and high content screening for drug discovery in kinase related diseases;</p>
    Color and Shape:Odour Solid

    Ref: TM-L1600

  • MCX 28
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    MCX 28

    CAS:
    <p>MCX 28, a triple PI3K/mTOR/PIM inhibitor, displays low nanomolar activity.</p>
    Formula:C25H19N5O4S3
    Color and Shape:Solid
    Molecular weight:549.64

    Ref: TM-T38839

  • FDA-Approved Kinase Inhibitor Library
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    FDA-Approved Kinase Inhibitor Library

    <p>A unique collection of 263 kinase inhibitors/regulators for specific targeting of kinases, ready for high-throughput screening and high-content screening.</p>
    Color and Shape:Liquid

    Ref: TM-L1610