mTOR
mTOR inhibitors are compounds that inhibit the activity of Mammalian Target of Rapamycin (mTOR), a central regulator of cell growth, proliferation, metabolism, and survival. The mTOR pathway is frequently altered in cancer and other diseases, making mTOR a critical target for therapeutic intervention. Inhibitors of mTOR are widely used in research related to cancer, aging, and metabolic disorders. At CymitQuimica, we offer a variety of mTOR inhibitors to support your research in signal transduction, oncology, and therapeutic development.
Found 144 products of "mTOR"
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(32-Carbonyl)-RMC-5552
CAS:<p>(32-Carbonyl)-RMC-5552, a potent mTOR inhibitor, blocks mTORC1/C2, with pIC50 values >9 for p-P70S6K and p-4E-BP1, and 8~9 for p-AKT1/2/3.</p>Formula:C93H134N10O24Color and Shape:SolidMolecular weight:1776.141YB-3-17
CAS:<p>YB-3-17 is a bifunctional molecule that can inhibit mTOR with an IC50 of 0.22 nM or degrade the G1 to S phase transition 1 gene (GSPT1) through the PROTAC mechanism, with a DC50 of 5 nM. It exhibits antiproliferative activity at nanomolar concentrations in various glioblastoma cell lines. Additionally, YB-3-17 shows antitumor activity in mouse models. (Pink: ligand for target protein; Black: linker; Blue: ligand for E3 ligase Cereblon)</p>Formula:C38H39N11O6Color and Shape:SolidMolecular weight:745.786PI3K-IN-22
CAS:<p>PI3K-IN-22 is a dual kinase inhibitor of PI3Kα and mTOR, with IC50s of 0.9 and 0.6 nM respectively. PI3K-IN-22 could be used in cancer.</p>Formula:C31H35F3N8O3Color and Shape:SolidMolecular weight:624.66RMC-6272
CAS:<p>RMC-6272 (RM-006) is a bi-steric mTORC1 inhibitor with selective potency over mTORC2 and shows greater effects than Rapamycin on TSC2-deficient tumors.</p>Formula:C95H141FN6O27SColor and Shape:SolidMolecular weight:1850.25mTOR inhibitor-12
<p>mTOR inhibitor-12 (Compound 11), a selective, brain-penetrant mTOR inhibitor, exhibits no genotoxicity risk and is utilized in research pertaining to central</p>Formula:C19H24N6O2SPurity:98%Color and Shape:SolidMolecular weight:400.5mTOR inhibitor-14
<p>mTOR Inhibitor-14 (compound 14c) is a potent inhibitor of mTOR with minimal inhibition of CYP2C8 and has demonstrated the capability to inhibit tumor growth [1</p>Purity:98%Color and Shape:Odour SolidRMC-4627
CAS:<p>RMC-4627 is a selective mTORC1 inhibitor that activates 4EBP1 and inhibits tumor growth.</p>Formula:C93H141N11O23Color and Shape:SolidMolecular weight:1781.17Cbz-B3A
CAS:<p>Cbz-B3A is a potent inhibitor of mTORC1 signalling, inhibits phosphorylation of eIF4E-binding protein 1 (4EBP1) and blocks translation by 68%.</p>Formula:C35H58N6O9Purity:98.59%Color and Shape:SolidMolecular weight:706.87Anti-Phospho-mTOR (Ser2481) Antibody (4R8)
<p>Anti-Phospho-MTOR (Ser2481) Antibody (4R8) is an antibody targeting Phospho-MTOR (Ser2481). Anti-Phospho-MTOR (Ser2481) Antibody (4R8) can be used in ELISA, WB, IF.</p>Color and Shape:Odour LiquidS6K1-IN-DG2
CAS:<p>S6K1-IN-DG2(S6K1InhibitorDG2) is a potent p70S6K inhibitor with an IC50 value of less than 100 nM.</p>Formula:C16H17BrN6OPurity:99.25%Color and Shape:SolidMolecular weight:389.25RMC-5552
CAS:<p>RMC-5552 selectively inhibits mTORC1 with ~40-fold selectivity over mTORC2, demonstrating anticancer activity and research utility.</p>Formula:C93H136N10O24Color and Shape:SolidMolecular weight:1778.16Anti-Phospho-MTOR (Ser2448) Antibody (2K503)
<p>Anti-Phospho-MTOR (Ser2448) Antibody (2K503) is an antibody targeting Phospho-MTOR (Ser2448). Anti-Phospho-MTOR (Ser2448) Antibody (2K503) can be used in ELISA, WB, IHC, IF.</p>Color and Shape:Odour LiquidLupiwighteone
CAS:<p>Lupiwighteone has anti-angiogenesis potential, it also has anticancer and cancer preventive effects on SH-SY5Y cells.</p>Formula:C20H18O5Purity:98.92%Color and Shape:SolidMolecular weight:338.35Omipalisib
CAS:<p>Omipalisib (GSK2126458) is a small-molecule pyridylsulfonamide inhibitor of phosphatidylinositol 3-kinase (PI3K) with potential antineoplastic activity.</p>Formula:C25H17F2N5O3SPurity:98% - 99.8%Color and Shape:SolidMolecular weight:505.5mTOR inhibitor-1
CAS:<p>C-4 is a potential ATP-competitive inhibitor of mTOR. C-4 could inhibit cell growth and proliferation.</p>Formula:C16H15BrN2O3Purity:99.43%Color and Shape:SolidMolecular weight:363.21Mito-LND
CAS:<p>Mito-LND (Mito-Loidamine) is an orally active and mitochondria-targeted inhibitor of oxidative phosphorylation.</p>Formula:C43H45BrCl2N3OPPurity:97.25% - 98.34%Color and Shape:SolidMolecular weight:801.62Samotolisib
CAS:<p>Samotolisib (LY3023414) inhibits PI3K, DNA-PK, mTOR; tested for solid tumors including breast and colon cancer.</p>Formula:C23H26N4O3Purity:98.41% - 99.69%Color and Shape:SolidMolecular weight:406.48Corynoxine
CAS:<p>Corynoxine is a tetracyclic oxindole alkaloid isolated from Uncaria macrophylla.</p>Formula:C22H28N2O4Purity:96.83% - 99.93%Color and Shape:SolidMolecular weight:384.47Salidroside
CAS:<p>Salidroside is a bioactive phenolic glycoside compound isolated from Rhodiola rosea and is a prolyl endopeptidase inhibitor.Cost-effective and quality-assured.</p>Formula:C14H20O7Purity:97.81%Color and Shape:Red-Brown Fine PowderMolecular weight:300.3PF-04691502
CAS:<p>PF-04691502 is a potent and selective inhibitor of PI3K and mTOR kinases with antitumor activity.</p>Formula:C22H27N5O4Purity:96.27% - ≥95%Color and Shape:SolidMolecular weight:425.48
