
Organometallic Ligands
Subcategories of "Organometallic Ligands"
- Buchwald Ligands(22 products)
- DPEN(4 products)
- DPHEN(4 products)
- JOSIPHOS(4 products)
- Phosphine(497 products)
- Porphirines(75 products)
Found 2889 products of "Organometallic Ligands"
Tezacaftor
CAS:Potentiates cystic fibrosis transmembrane conductance regulator (CFTR)Formula:C26H27F3N2O6Purity:Min. 95%Color and Shape:White PowderMolecular weight:520.5 g/molAR-R 17779 hydrochloride
CAS:AR-R 17779 is a selective agonist for α7 nicotinic acetylcholine receptors (nAChRs) (Ki value = 190 nM for rat α7 receptor). This compound has use as a tool to study the function of α7 nicotinic receptors. One such study revealed a role for α7 nicotinic receptors in nicotine-mediated excitatory effects on hippocampal learning and memory. AR-R17779 reduces formation of atherosclerotic plaques and abdominal aortic aneurysms in apolipoprotein E-deficient mice.Formula:C9H14N2O2•HClPurity:Min. 95%Color and Shape:White PowderMolecular weight:218.68 g/molMotesanib
CAS:Inhibitor of VEGFR, PDGR, c-Kit and Ret; inhibitor of angiogenesisFormula:C22H23N5OPurity:Min. 95%Molecular weight:373.45 g/molBosentan - Bio-X ™
CAS:Bosentan is a dual endothelin receptor antagonist that is used to treat hypertension. This drug works by blocking the action of endothelin molecules which prevents the narrowing of blood vessels and decreases blood pressure.
Formula:C27H29N5O6SPurity:Min. 95%Color and Shape:PowderMolecular weight:551.62 g/molIcilin - Bio-X ™
CAS:Icilin is a transient receptor potential M8 (TRPM8) agonist drug that is used for the treatment of pruritis. This drug has shown to be effective in producing an extreme cold sensation in both human and animal models. It is used in research for studying TRP channels.Formula:C16H13N3O4Purity:Min. 95%Color and Shape:PowderMolecular weight:311.29 g/molPLX 4032
CAS:BRAF kinase inhibitor; antineoplasticFormula:C23H18ClF2N3O3SPurity:Min. 95%Color and Shape:PowderMolecular weight:489.92 g/molPrilocaine HCl - Bio-X ™
CAS:Prilocaine is a drug used as a local anaesthetic in dental procedures. It has been shown to reduce the incidence of pain caused. This drug is also a sodium channel blocker that blocks the influx of sodium into cells.Formula:C13H20N2O•HClPurity:Min. 95%Color and Shape:PowderMolecular weight:256.77 g/molFingolimod phosphate
CAS:Sphingosine-1-phosphate (S1P) receptor agonist; antineoplastic, immunosppressant
Formula:C19H34NO5PPurity:Min. 95%Color and Shape:PowderMolecular weight:387.45 g/molNabumetone - Bio-X ™
CAS:Nabumetone is a non-steroidal anti-inflammatory drug that is used in the treatment of osteoarthritis and rheumatoid arthritis. This drug is also a cyclooxygenase inhibitor and works by inhibiting this enzyme so that pain and inflammation is reduced.Formula:C15H16O2Purity:Min. 95%Color and Shape:PowderMolecular weight:228.29 g/mol(-)-Sparteine hydroiodide
CAS:Sparteine hydroiodide is the salt form of sparteine. This compound acts as an inhibitor of voltage-gated sodium channels. In organic chemisty, it is used for chiral synthesis.Formula:C15H26N2•HIPurity:Min. 95%Molecular weight:362.29 g/molAfatinib - Bio-X ™
CAS:Afatinib is a small molecule that inhibits the activity of cellular kinases that are involved in the progression of cancer. It is an Irreversible inhibitor of three members of the ErbB family. This molecule binds covalently to cysteine 797 residue in HER2 and blocks downstream cellular signalling which inhibits cellular growth and promotes apoptosis. It has been researched for the treatment of non-small cell lung cancer (NSCLC), breast cancer, pancreatic cancer and colorectal cancer.Formula:C24H25ClFN5O3Purity:Min. 95%Color and Shape:PowderMolecular weight:485.94 g/molCarmustine - Bio-X ™
CAS:Carmustine is a DNA alkylating agent which also cross-links DNA. As a result, Carmustine disrupts the function of DNA, resulting in the arrest the cell cycle and apoptosis. Consequently these properties of Carmustine, in addition to its ability to easily transmit through the blood-brain barrier, means it can be used as a cancer treatment, treating cancers such as, breast, ovarian and pancreatic as well as lymphomas and leukemias. Furthermore Carmustine can contribute to cytotoxic effects through its ability to carbamoylate DNA repair enzymes and proteins.Formula:C5H9Cl2N3O2Purity:Min. 95%Color and Shape:PowderMolecular weight:214.05 g/molGefitinib hydrochloride
CAS:RIPK2 protein kinase inhibitor; EGFR inhibitorFormula:C22H24ClFN4O3·HClPurity:Min. 95%Color and Shape:PowderMolecular weight:483.36 g/molTandospirone
CAS:Tandospirone is a psychotropic drug that acts as a selective serotonin receptor partial agonist. It is derived from a synthetic source, specifically targeting the 5-HT1A receptors in the brain. Tandospirone modulates serotonergic neurotransmission by binding to these receptors, which are associated with mood regulation. This action results in the anxiolytic and antidepressant effects observed with the drug.Formula:C21H29N5O2Purity:Min. 95%Molecular weight:383.49 g/molBenazepril HCl - Bio-X ™
CAS:Benazepril is a nonsteroidal anti-inflammatory drug that can be used to treat hypertension, heart failure and renal failure. It is an angiotensin-converting enzyme (ACE) inhibitor that blocks the conversion of angiotensin I to angiotensin II. This inhibition prevents the vasoconstrictive effects of this peptide, which are mediated through activation of the renin-angiotensin system.Formula:C24H28N2O5•HClPurity:Min. 95%Color and Shape:PowderMolecular weight:460.95 g/molSB 239063
CAS:Inhibits p38 MAP kinase; anti-inflammatory; neuroprotectiveFormula:C20H21FN4O2Purity:Min. 95%Color and Shape:PowderMolecular weight:368.4 g/molBIO
CAS:Specific inhibitor of glycogen synthase kinase 3 (GSK-3) with IC50 in low nanomolar range. Studies showed that BIO maintains self-renewal in embryonic stem cells (ESCs) as well as increases activity of β-catenin. In neonatal cardiomyocytes, BIO promotes cell cycle by stimulating cell entry into S phase as well as cytokinesis. In germline stem cells from female mice (FGSCs), BIO promoted proliferation and maintenance of FGSCs by activating β-catenin and up-regulating E-cadherin.Formula:C16H10BrN3O2Purity:Min. 95%Color and Shape:Red To Dark Red SolidMolecular weight:356.17 g/molDapoxetine hydrochloride - Bio-X ™
CAS:Controlled ProductDapoxetine is a drug that belongs to the group of selective serotonin reuptake inhibitors (SSRIs). It is used to treat premature ejaculation. This drug inhibits the serotonin transporter allowing for an increased action of serotonin at the postsynaptic cleft, thus promoting ejaculatory delay.Formula:C21H24ClNOPurity:Min. 98 Area-%Color and Shape:PowderMolecular weight:341.87 g/molS26131
CAS:S26131 is an advanced glycation end product (AGE) inhibitor, which is a synthetic compound designed for laboratory research purposes. It is derived from chemical synthesis processes, offering a robust tool for investigating the biochemical pathways associated with glycation. Its mechanism of action involves the inhibition of AGE formation, which is a post-translational modification resulting from the non-enzymatic reaction between sugars and proteins or lipids. This biochemical modulation is vital for studying the implications of glycation in various physiological and pathological contexts.
Formula:C31H34N2O4Purity:Min. 95%Molecular weight:498.6 g/molTacrolimus - Bio-X ™
CAS:Tacrolimus is a calcineurin inhibitor drug that is used for the prevention of rejection after an organ transplant. This drug can also be used in the treatment of severe atopic dermatitis. Tacrolimus’ mechanism of action is not well known however it is understood that this drug inhibits T-lymphocyte activation by binding to an intracellular protein called FKBP-12. This drug also has anti-inflammatory properties.
Formula:C44H69NO12Purity:Min. 95%Color and Shape:White Off-White PowderMolecular weight:804.02 g/mol
