
Organometallic Ligands
Subcategories of "Organometallic Ligands"
- Buchwald Ligands(22 products)
- DPEN(4 products)
- DPHEN(4 products)
- JOSIPHOS(4 products)
- Phosphine(497 products)
- Porphirines(75 products)
Found 2889 products of "Organometallic Ligands"
PNU 159682
CAS:DNA alkylating agent; highly potent metabolite of nemorubicinFormula:C32H35NO13Purity:Min. 90 Area-%Color and Shape:Red PowderMolecular weight:641.62 g/molMotesanib
CAS:Inhibitor of VEGFR, PDGR, c-Kit and Ret; inhibitor of angiogenesisFormula:C22H23N5OPurity:Min. 95%Molecular weight:373.45 g/mol(R)-ADX 47273
CAS:Positive allosteric modulator of the metabotropic glutamate receptor mGluR5 with EC50 in submicromolar range. The compound is able to increase mGluR5 function in vitro and in vivo. A study showed that ADX-47273 enhanced fear extinction learning as well as improved reversal learning in experimental animals.
Formula:C20H17F2N3O2Purity:Min. 95%Color and Shape:SolidMolecular weight:369.36 g/molSB 239063
CAS:Inhibits p38 MAP kinase; anti-inflammatory; neuroprotectiveFormula:C20H21FN4O2Purity:Min. 95%Color and Shape:PowderMolecular weight:368.4 g/molH 151
CAS:A potent inhibitor of STING protein (stimulator of interferon genes), a protein that partakes in intracellular DNA sensing pathway. H 151 blocks palmitoylation of STING, which is required for the formation of multimeric complexes for recruiting downstream signalling molecules. Inhibition of STING by H 151 reduces pro-inflammatory cytokine synthesis.Formula:C17H17N3OPurity:Min. 95%Color and Shape:SolidMolecular weight:279.34 g/molLafutidine
CAS:Histamine (H2) receptor antagonist; treats ulcers and acid refluxFormula:C22H29N3O4SPurity:Min. 95%Molecular weight:431.55 g/molValiglurax
CAS:Potent and selective positive allosteric modulator (PAM) of metabotropic glutamate receptor mGlu4. Valiglurax is orally bioavailable and CNS-penetrant mGlu4 PAM in preclinical development for the Parkinson’s disease therapy and alleviation of the motor symptoms.Formula:C16H10F3N5Purity:Min. 95%Color and Shape:SolidMolecular weight:329.28 g/molBRD 6989
CAS:A small molecule inhibitor with high selectivity for CDK8 over CDK19. Increases IL-10 production in stimulated human and murine macrophages and dendritic cells. Modulatory action on inflammatory responses has therapeutic potential.Formula:C16H16N4Purity:Min. 95%Color and Shape:SolidMolecular weight:264.33 g/molAG 221
CAS:Inhibitor of isocitrate dehydrogenase 2Formula:C19H17F6N7OPurity:Min. 95%Color and Shape:PowderMolecular weight:473.38 g/molABTL-0812
CAS:ABTL-0812 is an investigational anticancer compound, which is a synthetic small molecule with a novel mechanism of action. It is derived from the research efforts focused on targeting key metabolic pathways in cancer cells. The mode of action of ABTL-0812 involves the modulation of the Akt/mTOR pathway, leading to the induction of autophagy-mediated cell death, a process that is selectively cytotoxic to cancer cells.Formula:C18H32O3Purity:Min. 95%Color and Shape:PowderMolecular weight:296.4 g/molMCC 950 sodium
CAS:Inhibitor of NLRP3 inflammasome and suppressor of the inflammatory cytokine IL-1β secretion. The compound was tested in diabetic mice and was shown to decrease the incidence of cardiac arrythmias, which are common secondary complications in diabetes mellitus. MCC 950 has potential to reverse diabetes-induced pathologies in cardiac electrophysiology.Formula:C20H23N2O5S·NaPurity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:426.46 g/molQ-VD-OPH
CAS:Inhibitor of caspases; broad spectrumFormula:C26H25F2N3O6Purity:Min. 98.00 Area-%Color and Shape:PowderMolecular weight:513.49 g/molGDC 0941
CAS:Pan-class I phosphatidylinositide 3-kinase (PI3K) inhibitor (IC50 = 3, 33, 3 and 75 nM at catalytic subunits p110α, p110β, p110δ and p110γ respectively). Inhibits proliferation in several cancer cell lines, such as glioblastoma, breast and prostate cancer cells. Has synergistic anti-cancer effect in combination with MEK/ERK kinase inhibitor GDC-0973 (cobimetinib).
Formula:C23H27N7O3S2Purity:Min. 95%Color and Shape:White PowderMolecular weight:513.64 g/mol7-Prenyloxycoumarin
CAS:7-Prenyloxycoumarin is a naturally occurring compound, often categorized as a phytochemical, which is primarily isolated from various plant sources including the Rutaceae family. This compound exhibits intriguing biochemical properties due to its unique molecular structure, primarily the presence of a prenyloxy group attached to the coumarin core. The mode of action of 7-Prenyloxycoumarin primarily involves its ability to interact with biological membranes and proteins, leading to modulation of enzymatic activity and disruption of pathogen cell walls.Formula:C14H14O3Purity:Min. 98 Area-%Color and Shape:PowderMolecular weight:230.26 g/molNAcM-OPT
CAS:Inhibits N-Acetyl-mediated interaction between BE2M (E2 conjugating enzyme) and DCN1 (a component of E3 ligase complex). Also has inhibitory action on DCN2 and NEDD8 ubiquitin-like protein. Reduces anchorage-independent growth in DCN1-amplified cell line.Formula:C23H29Cl2N3OPurity:Min. 95%Color and Shape:solid.Molecular weight:434.4 g/molIrsogladine maleate - Bio-X ™
CAS:Irsogladine is a gastroprotective drug that is used for the treatment of GERD and gastric ulcers. This drug also has antioxidant properties. Irsogladine is a phosphodiesterase-4 inhibitor and increases levels of cAMP. It helps to prevent and heal damage to the stomach lining.Formula:C13H11Cl2N5O4Purity:Min. 95%Color and Shape:PowderMolecular weight:372.16 g/molBosentan - Bio-X ™
CAS:Bosentan is a dual endothelin receptor antagonist that is used to treat hypertension. This drug works by blocking the action of endothelin molecules which prevents the narrowing of blood vessels and decreases blood pressure.
Formula:C27H29N5O6SPurity:Min. 95%Color and Shape:PowderMolecular weight:551.62 g/molLY 411575
CAS:Potent inhibitor of γ-secretase. LY 411575 inhibited production of amyloid β (Aβ) peptides with IC50 of 0.078 nM in vitro as well as decreased levels of Aβ40 and Aβ42 amyloids in brain of a mouse model for Alzheimer’s disease. In vitro studies confirmed that LY 411575 inhibited cleavage of Notch receptor at S3 site with IC50 of 0.39 nM, which blocked Notch activation and downstream signalling, leading to apoptosis in primary and immortalized Kaposi's sarcoma cells.Formula:C26H23F2N3O4Purity:Min. 95%Color and Shape:SolidMolecular weight:479.48 g/molBrimonidine-D-tartrate
CAS:Brimonidine-D-tartrate is a selective alpha-2 adrenergic agonist, which is a pharmacological compound derived synthetically, targeting specific receptor subtypes in the adrenergic receptor family. Its mode of action involves reducing aqueous humor production and increasing uveoscleral outflow in the eye, thereby lowering intraocular pressure. Additionally, it induces peripheral vasoconstriction, playing a role in reducing redness in rosacea.Formula:C15H16BrN5O6Color and Shape:White PowderMolecular weight:442.22 g/molPipethanate ethobromide
CAS:Prostaglandin E2 (EP2) receptor antagonistFormula:C23H30NO3•BrPurity:Min. 95%Color and Shape:White PowderMolecular weight:448.39 g/mol
