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Cytoskeletal Signaling

Cytoskeletal Signaling

Cytoskeletal signaling inhibitors are compounds that disrupt the signaling pathways regulating the cytoskeleton, which is crucial for cell shape, motility, division, and intracellular transport. These inhibitors are used to study the dynamics of cytoskeletal proteins, such as actin and tubulin, and their role in processes like cell migration, adhesion, and cancer metastasis. Cytoskeletal signaling inhibitors are valuable in research on cell biology, cancer, and neurobiology. At CymitQuimica, we offer a comprehensive range of high-quality cytoskeletal signaling inhibitors to support your research in these areas.

Found 1382 products of "Cytoskeletal Signaling"

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  • Pre-084

    CAS:
    <p>Pre-084 is a high affinity, selective σ1 agonist.</p>
    Formula:C19H28ClNO3
    Purity:99.91%
    Color and Shape:Solid
    Molecular weight:353.88
  • Shepherdin 79-87 acetate


    <p>Shepherdin 79-87 acetate is a peptidomimetic antagonist of the complex between Hsp90 and survivin, another key regulator of tumor cell viability.</p>
    Formula:C43H68N12O14S
    Purity:98.08%
    Color and Shape:Solid
    Molecular weight:1009.14
  • AZ13705339 hemihydrate


    <p>AZ13705339 hemihydrate: potent PAK1 inhibitor (IC50: 0.33 nM), also binds PAK1/2 (Kd: 0.28/0.32 nM), for cancer research.</p>
    Formula:C33H36FN7O3SH2O
    Color and Shape:Solid
    Molecular weight:638.77
  • Bexotegrast

    CAS:
    <p>Bexotegrast (PLN-74809) is an αvβ6 and αvβ1 integrin inhibitor with antifibrotic properties for the study of idiopathic pulmonary fibrosis (IPF).</p>
    Formula:C27H36N6O3
    Purity:99.53%
    Color and Shape:Solid
    Molecular weight:492.61
  • Alvespimycin

    CAS:
    <p>Alvespimycin (17-DMAG) is a potent Hsp90 inhibitor with potential anticancer activity, which acts by binding to Hsp90.</p>
    Formula:C32H48N4O8
    Purity:99.88%
    Color and Shape:Solid
    Molecular weight:616.75
  • FAK activator 1

    CAS:
    <p>ZINC40099027 is a FAK activator that induces gastric mucosal repair in persistent aspirin-associated gastric injury.</p>
    Formula:C23H26F3N3O3
    Purity:99.19%
    Color and Shape:Soild
    Molecular weight:449.47
  • RO0270608

    CAS:
    <p>RO0270608 is an α4β1/α4β7 integrin antagonist with anti-inflammatory activity for the study of allergic inflammatory responses.</p>
    Formula:C24H19Cl3N2O4
    Purity:98.26%
    Color and Shape:Solid
    Molecular weight:505.78
  • Muromonab

    CAS:
    <p>Muromonab (OKT3) is a mouse-derived antibody targeting the CD3 receptor, blocking all cytotoxic T cell functions.</p>
    Purity:95% - 97.51% (SEC-HPLC)
    Color and Shape:Liquid
  • Neurodazine

    CAS:
    <p>Neurodazine is a neural inducer that promotes the differentiation of pluripotent cells into neuronal cells.</p>
    Formula:C27H21ClN2O3
    Purity:98.01%
    Color and Shape:Solid
    Molecular weight:456.92
  • Bosutinib hydrate

    CAS:
    <p>Bosutinib hydrate (SKI-606 hydrate) is a kinase inhibitor of BCR-ABL and Src tyrosine kinases for the study of leukemia.</p>
    Formula:C26H31Cl2N5O4
    Purity:99.87%
    Color and Shape:Solid
    Molecular weight:548.46
  • Etaracizumab

    CAS:
    <p>Etaracizumab (LM 609) is a humanized monoclonal antibody targeting integrin αvβ3, inhibiting angiogenesis and melanoma growth, used in the study of melanoma.</p>
    Purity:96.77% (SEC-HPLC) - 99.32% (SEC-HPLC)
    Color and Shape:Liquid
    Molecular weight:144.3 (kDa)
  • Vevorisertib trihydrochloride

    CAS:
    <p>Vevorisertib trihydrochloride (ARQ 751 trihydrochloride) is ainhibitor of pan-AKT and AKT1-E17K mutations, inhibiting AKT1, AKT2 and AKT3.</p>
    Formula:C35H41Cl3N8O
    Purity:98.28%
    Color and Shape:Solid
    Molecular weight:696.12
  • Ruboxistaurin hydrochloride

    CAS:
    <p>Ruboxistaurin HCl (LY 333531) selectively inhibits PKCβI/II with IC50 of 4.7/5.9 nM; much less effective on other PKC types and ATP-kinases.</p>
    Formula:C28H28N4O3·HCl
    Purity:98.44% - 99.22%
    Color and Shape:Solid
    Molecular weight:505.01
  • H-Ile-Lys-Val-Ala-Val-OH

    CAS:
    <p>H-Ile-Lys-Val-Ala-Val-OH can induce rapid differentiation of neural progenitor cells into neurons and neurite growth.</p>
    Formula:C25H48N6O6
    Purity:99.92%
    Color and Shape:Solid
    Molecular weight:528.69
  • Arg-Gly-Asp-Ser

    CAS:
    <p>Arg-Gly-Asp-Ser (RGDS peptide) is a conserved tetrapeptide sequence found in fibronectin, and the von Willebrand factor.</p>
    Formula:C15H27N7O8
    Purity:98.29%
    Color and Shape:Solid
    Molecular weight:433.42
  • NQTrp

    CAS:
    <p>NQTrp is an inhibitor of the aggregation of the tau protein with generic anti-amyloidogenic effects.</p>
    Formula:C21H16N2O4
    Purity:98.35%
    Color and Shape:Solid
    Molecular weight:360.36
  • Mps1-IN-2

    CAS:
    <p>Mps1-IN-2 is a potent, selective and ATP-competitive dual Mps1/Plk1 inhibitor.</p>
    Formula:C26H36N6O3
    Purity:96.24% - 99.75%
    Color and Shape:Solid
    Molecular weight:480.6
  • WZU-13

    CAS:
    <p>WZU-13 is an inhibitor of carboxylesterase (CES). At a concentration of 100 μM, WZU-13 suppresses 77% of CES activity.</p>
    Formula:C22H16N2O
    Color and Shape:Solid
    Molecular weight:324.38
  • Anti-Mouse CD3ε Antibody (145-2C11)


    <p>Anti-Mouse CD3ε Antibody (145-2C11) is an antibody inhibitor targeting CD3ε in Armenian hamsters, in TCR formation and in T lymphocyte activation</p>
    Purity:99%
    Color and Shape:Odour Liquid
  • ST-401

    CAS:
    <p>ST-401, a microtubule-targeting agent (MTA), functions as a brain-penetrant microtubule (MT) assembly inhibitor. It disrupts microtubule (MT) function by gently and reversibly reducing MT assembly, which leads to mitotic delay and interphase cell death. ST-401 demonstrates potent antitumor activity.</p>
    Formula:C24H20N2O
    Color and Shape:Solid
    Molecular weight:352.43
  • Vepsitamab

    CAS:
    <p>Vepsitamab (AMG 199), an anti-MUC17/CD3 BiTE, targets T cells and tumors for cell lysis and T cell activation.</p>
    Color and Shape:Liquid
  • Pinatuzumab

    CAS:
    <p>Pinatuzumab is a humanised monoclonal antibody targeting CD22, B-cell malignancies non-Hodgkin lymphoma (NHL) and chronic lymphocytic leukaemia (CLL).</p>
    Purity:95%
    Color and Shape:Liquid
  • Pasotuxizumab

    CAS:
    <p>Pasotuxizumab (BAY 2010112) is a BiTE that targets PSMA &amp; CD3 with K D s 47.0 &amp; 9.4 nM, for mCRPC research.</p>
    Color and Shape:Liquid
  • Tepoditamab

    CAS:
    <p>Tepoditamab (MCLA-117) is a bispecific antibody targeting CLEC12A and CD3, inducing T cell lysis of AML cells.</p>
    Color and Shape:Liquid
  • Gresonitamab

    CAS:
    <p>Gresonitamab (AMG 910) is an HLE BiTE antibody targeting CD3+ T cells and CLDN18.2+ tumors, for adenocarcinoma research.</p>
    Color and Shape:Liquid
  • Obrindatamab

    CAS:
    <p>Obrindatamab: a humanized bispecific antibody targeting B7-H3/CD3, enhances CTL-mediated cancer cell killing.</p>
    Color and Shape:Liquid
  • Enlimomab

    CAS:
    <p>Enlimomab (BI-RR 0001), a mouse IgG2a antibody, blocks leukocyte binding to ICAM-1, reducing inflammation and used in stroke research.</p>
    Color and Shape:Liquid
  • Nivatrotamab


    <p>Nivatrotamab: Humanized anti-GD2/CD3 bispecific antibody for neuroblastoma research.</p>
    Color and Shape:Odour Liquid
  • Semorinemab

    CAS:
    <p>Semorinemab (RG6100) is a humanised monoclonal antibody targeting the N-terminal domain of tau protein with a Kd of 3.8 nM, suitable for Alzheimer's disease.</p>
    Purity:95% - 95%
    Color and Shape:Liquid
  • 4-Desacetylvinblastine hydrazide

    CAS:
    <p>Deacetylvinblastine hydrazide, a cytotoxic vinca alkaloid often conjugated with folic acid to produce EC145, a novel folate-receptor targeted agent.</p>
    Formula:C43H56N6O7
    Color and Shape:Solid
    Molecular weight:768.94
  • Raludotatug

    CAS:
    <p>Raludotatug is a humanized antibody targeting cadherin-6 (CDH6). As part of the ADC Raludotatug deruxtecan, it shows promise in researching platinum-sensitive ovarian cancer.</p>
    Purity:95% - 95%
    Color and Shape:Liquid
  • Gosuranemab

    CAS:
    <p>Gosuranemab (BMS-986168), a humanized IgG4 mAb, targets tau residues 15-22, and may aid in Alzheimer’s research.</p>
    Purity:95% - 95%
    Color and Shape:Liquid
  • Meclofenamate sodium hydrate

    CAS:
    <p>Meclofenamate sodium: a strong NSAID inhibiting leukocyte function—chemotaxis, degranulation, and radical production.</p>
    Formula:C14H12Cl2NNaO3
    Color and Shape:Solid
    Molecular weight:336.15
  • Posdinemab

    CAS:
    <p>Posdinemab, a humanized IgG1κ antibody, targets the microtubule-associated protein tau (MAPT) [1].</p>
    Color and Shape:Liquid
  • Plamotamab

    CAS:
    <p>Plamotamab (XmAb-13676) is a bispecific antibody targeting CD3 and CD20, recruiting T cells to destroy CD20+ tumors and causing mild hematologic reactions.</p>
    Color and Shape:Liquid
  • Anti-Mouse IL-1a Antibody (ALF-161)


    <p>Anti-Mouse IL-1a Antibody is an IgG1 subtype inhibitor specific to mouse IL-1a, derived from the Armenian Hamster.</p>
    Purity:98%
    Color and Shape:Odour Liquid
  • Ubamatamab

    CAS:
    <p>Ubamatamab (REGN4018), a human bispecific antibody targeting Mucin 16 (MUC16) and CD3, exhibits potent antitumor activity [1].</p>
    Color and Shape:Liquid
  • Osemitamab

    CAS:
    <p>Osemitamab (TST001) is a humanised monoclonal antibody targeting claudin-18.2, gastric/gastric-oesophageal junction adenocarcinoma, PDAC, and lung cancer.</p>
    Purity:95%
    Color and Shape:Liquid
  • Voxalatamab

    CAS:
    <p>Voxalatamab (JNJ-63898081), an IgG4 bispecific antibody targeting PSMA and CD3, demonstrates anti-cancer efficacy in prostate cancer research [1].</p>
    Color and Shape:Liquid
  • Vonsetamig

    CAS:
    <p>Vonsetamig, a humanized immunoglobulin G4-kappa monoclonal antibody, targets both TNFRSF17 and CD3E. It serves as an antineoplastic agent.</p>
    Color and Shape:Liquid
  • Flotetuzumab

    CAS:
    <p>Flotetuzumab (MGD006/S80880) is a CD123/CD3 bispecific DART antibody, reactivating T-cells for AML treatment.</p>
    Color and Shape:Liquid
  • Pacanalotamab

    CAS:
    <p>Pacanalotamab (AMG 420/BI-836909), a BiTE, directs T-cells to BCMA+ MM cells, causing lysis.</p>
    Color and Shape:Liquid
  • Vibecotamab

    CAS:
    <p>Vibecotamab, a bispecific antibody, targets CD123/CD3 for T-cell killing of tumors, promising for acute myeloid leukemia.</p>
    Color and Shape:Liquid
  • OS-2966


    <p>OS-2966 is a humanised de-immunised monoclonal antibody that target Integrin b1/ITGB1/CD29, malignant gliomas, glioblastomas, and astrocytomas.</p>
    Purity:95%
    Color and Shape:Odour Liquid
  • Rovelizumab

    CAS:
    <p>Rovelizumab: humanized anti-CD11/CD18 antibody for MS, hemorrhagic shock, MI, and stroke research.</p>
    Color and Shape:Liquid
  • Lixudebart

    CAS:
    <p>Lixudebart is a humanised monoclonal antibody targeting CLDN1 (Claudin-1), which can be used to reverse organ fibrosis and reduce initial ALT/AST levels.</p>
    Purity:95%
    Color and Shape:Liquid
  • Vatelizumab

    CAS:
    <p>Vatelizumab is a humanised monoclonal antibody targeting Integrin α2β1 ( VLA-2, CD49b), which enhances the frequency of regulatory T cells multiple sclerosis.</p>
    Purity:95%
    Color and Shape:Liquid
  • Linvoseltamab

    CAS:
    <p>Linvoseltamab, a bispecific antibody, targets both BCMA (TNFRSF17) and CD3 epsilon, demonstrating a favorable safety profile and promising efficacy in relapsed/</p>
    Color and Shape:Liquid
  • Cevostamab

    CAS:
    <p>Cevostamab (BFCR4350A, RG6160, RO7187797) is a humanized BsAb IgG1 targeting FcRH5 on MM cells and CD3 on T cells to enhance T-cell-mediated MM cell killing.</p>
    Color and Shape:Liquid
  • Odronextamab

    CAS:
    <p>Odronextamab, a fully human, hinge-stabilized IgG4-based bispecific antibody, targets CD3 receptors on T cells and CD20 receptors on B cells [1].</p>
    Color and Shape:Liquid
  • Pavurutamab

    CAS:
    <p>Pavurutamab (AMG-701) is a bispecific T cell engager targeting CD3 and BCMA with extended half-life, designed to treat MM.</p>
    Color and Shape:Liquid
  • 17-AEP-GA

    CAS:
    <p>17-AEP-GA is an HSP90 antagonist and a potent inhibitor of glioblastoma cell proliferation, survival, migration and invasion.</p>
    Formula:C34H50N4O8
    Purity:97.77% - 99.56%
    Color and Shape:Solid
    Molecular weight:642.78
  • Tubulin polymerization-IN-2

    CAS:
    <p>Tubulin-IN-2, anticancer β-tubulin binder, IC50 0.92 μM, effective against various cancers.</p>
    Formula:C17H12F2N2O2
    Color and Shape:Solid
    Molecular weight:314.29
  • Meclofenamic acid

    CAS:
    <p>Meclofenamic acid: non-selective gap-junction blocker, FTO inhibitor, anti-inflammatory.</p>
    Formula:C14H11Cl2NO2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:296.15
  • SB273005

    CAS:
    <p>SB273005 is a potent integrin inhibitor with Ki of 1.2 nM and 0.3 nM for αvβ3 receptor and αvβ5 receptor, respectively.</p>
    Formula:C22H24F3N3O4
    Purity:99.58%
    Color and Shape:Solid
    Molecular weight:451.44
  • N-Desmethylnefopam

    CAS:
    <p>N-Desmethylnefopam is the main Nefopam metabolite .</p>
    Formula:C16H17NO
    Purity:98%
    Color and Shape:Solid
    Molecular weight:239.31
  • Ionomycin calcium

    CAS:
    <p>Ionomycin calcium (SQ23377 calcium) is an effective and selective calcium ionophore, exhibiting high specificity for calcium ions. Cost-effective and quality-assured.</p>
    Formula:C41H70CaO9
    Purity:98% - 98.11%
    Color and Shape:Solid
    Molecular weight:747.07
  • Phorbol 12,13-dibutyrate

    CAS:
    <p>Phorbol 12,13-dibutyrate (Phorbol dibutyrate) is a PKC activator that induces contraction of isolated rabbit vascular smooth muscle.</p>
    Formula:C28H40O8
    Purity:99.32% - 99.37%
    Color and Shape:Solid
    Molecular weight:504.61
  • D-GsMTx4 TFA


    <p>D-GsMTx4 TFA, a selective spider venom peptide, is a TRPC1/6 and Piezo2 inhibitor that inhibits cation-permeable mechanosensitive channels (MSCs) belonging to the Piezo and TRP channel families, blocks cation-selective stretch-activated channels (SACs), and attenuates lysophosphatidylcholine (LPC)-induced astrocyte toxicity and microglia reactivity. toxicity and microglia reactivity.D-GsMTx4 TFA prevented myocardial infarction in a mouse model of ischemia/reperfusion and can be used to characterize the role of excitatory MSCs in normal physiology and pathology.</p>
    Formula:C187H279F3N48O48S6
    Purity:99.29% - 99.65%
    Color and Shape:Soild
    Molecular weight:4216.93
  • IPA-3

    CAS:
    <p>IPA-3 is a selective non-ATP competitive Pak1 inhibitor with IC50 of 2.5 μM, no inhibition to group II PAKs (PAKs 4-6).</p>
    Formula:C20H14O2S2
    Purity:97.40%
    Color and Shape:Solid
    Molecular weight:350.45
  • Tirofiban

    CAS:
    <p>Tirofiban (L700462) (MK-383) is a selective palate GPIIb/IIIa antagonist which inhibits platelet aggregation with IC50 of 9 nM.</p>
    Formula:C22H36N2O5S
    Purity:99.83%
    Color and Shape:Solid
    Molecular weight:440.6
  • Auristatin F

    CAS:
    <p>Auristatin F is an effective inhibitor of microtubule and vascular damaging agent. Auristatin F can be used in antibody-drug conjugates.</p>
    Formula:C40H67N5O8
    Purity:98.41% - 99.25%
    Color and Shape:Solid
    Molecular weight:745.99
  • Mps1-IN-1

    CAS:
    <p>Mps1-IN-1 is a potent, selective and ATP-competitive inhibitor of Mps1 kinase (IC50 : 367 nM )</p>
    Formula:C28H33N5O4S
    Purity:98.33%
    Color and Shape:Solid
    Molecular weight:535.66
  • BAY1217389

    CAS:
    <p>BAY 1217389 is an effective and selective inhibitor of the monopolar spindle 1 (MPS1) kinase (IC50&lt;10 nM).</p>
    Formula:C27H24F5N5O3
    Purity:98.14% - 99.42%
    Color and Shape:Solid
    Molecular weight:561.5
  • AS1938909

    CAS:
    <p>AS1938909: SHIP2 inhibitor boosts Akt phosphorylation, glucose use, and uptake via GLUT1 in L6 myotubes.</p>
    Formula:C19H13Cl2F2NO2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:428.28
  • IQTub4P

    CAS:
    <p>IQTub4P is a potent inhibitor of microtubules. IQTub4P exhibits cytotoxicity in HeLa cells (EC50: 170 nM).</p>
    Formula:C19H18NNa2O8P
    Color and Shape:Solid
    Molecular weight:465.305
  • HSP90-IN-14

    CAS:
    <p>HSP90-IN-14 inhibits Hsp90 (Kd=0.26 μM) and fights influenza A/H3N2, A/H1N1, B with EC50 of 2.6, 3.9, 17 μM in MDCK cells.</p>
    Formula:C14H8Cl2N4O4S
    Color and Shape:Solid
    Molecular weight:399.21
  • Microtubule inhibitor 4

    CAS:
    <p>Microtubule inhibitor 4 (Compound 2) blocks polymerization, toxic to HT-29 cells (IC50: 2.1 nM).</p>
    Formula:C25H23FN4O3
    Color and Shape:Solid
    Molecular weight:446.47
  • NC9 TG2 inhibitor

    CAS:
    <p>NC9 is an irreversible inhibitor of transglutaminase 2 (TG2) and also inhibits Factor XIIIA (FXIIIA).</p>
    Formula:C35H47N5O8S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:697.84
  • Antiproliferative agent-30

    CAS:
    <p>Antiproliferative agent-30 (Compound 8g) demonstrates broad-spectrum antiproliferative activity, with IC50 values of 0.054 nM, 0.008 nM, and 0.144 nM against</p>
    Formula:C24H26N4O4
    Color and Shape:Solid
    Molecular weight:434.49
  • Tubulin polymerization-IN-42

    CAS:
    <p>Tubulin polymerization-IN-42 (compound 10j), an indole-substituted furanone, inhibits tubulin polymerization and exhibits anti-cancer properties [1].</p>
    Formula:C22H21NO5
    Color and Shape:Solid
    Molecular weight:379.41
  • CCT251236

    CAS:
    <p>CCT251236 is an orally available Pirin ligand obtained from a heat shock transcription factor 1 (hsf1) phenotypic screen.</p>
    Formula:C32H32N4O5
    Purity:98.82% - 99.89%
    Color and Shape:Solid
    Molecular weight:552.62
  • GR 144053 trihydrochloride

    CAS:
    <p>platelet fibrinogen receptor glycoprotein IIb/IIIa (GpIIb/IIIa) antagonist</p>
    Formula:C18H30Cl3N5O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:454.82
  • Alyssin

    CAS:
    <p>Alyssin: sulforaphane analog, antioxidant; boosts Nrf2 and phase II enzymes in cancer cells; lowers PAH metabolism, reducing cancer risk in vitro.</p>
    Formula:C7H13NOS2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:191.31
  • CH5164840

    CAS:
    <p>CH5164840: strong HSP90 blocker; excels in NSCLC treatment; boosts erlotinib efficacy on EGFR-mutant tumors.</p>
    Formula:C19H23N5O2S
    Color and Shape:Solid
    Molecular weight:385.48
  • Tubulozole

    CAS:
    <p>Tubulozole blocks mitosis by inhibiting microtubule dynamics, leading to cell cycle arrest and apoptosis.</p>
    Formula:C23H23Cl2N3O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:508.42
  • SEW84

    CAS:
    <p>SEW84, an Aha1-stimulated Hsp90 inhibitor, has an IC50 of 0.3 μM, aiding protein deposition disease research.</p>
    Formula:C19H14F4N4OS
    Color and Shape:Solid
    Molecular weight:422.4
  • Hsp90-Cdc37-IN-1

    CAS:
    <p>Hsp90-Cdc37-IN-1 is an Hsp90-Cdc37 interaction disruptor (IC50: 140 nM) that inhibit cell migration and reverse drug resistance.</p>
    Formula:C43H57FN2O6S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:748.99
  • PP2A Cancerous-IN-1

    CAS:
    <p>PP2A Cancerous-IN-1 is a potent inhibitor of CIP2A (Cancerous inhibitor of PP2A) and p-Akt that exhibits potent anti-proliferative effects.</p>
    Formula:C30H24N4O3
    Color and Shape:Solid
    Molecular weight:488.54
  • OXi8007

    CAS:
    <p>OXi8007, a water-soluble prodrug for OXi8006, disrupts vasculature and exhibits strong cytotoxicity against DU-145 cancer cells.</p>
    Formula:C26H24NNa2O10P
    Color and Shape:Solid
    Molecular weight:587.428
  • Hsp90-IN-17

    CAS:
    <p>Hsp90-IN-17 (Example 5) is an inhibitor of HSP90, applicable in researching proliferative diseases, including cancer and neurodegenerative conditions.</p>
    Formula:C21H20N4O7
    Color and Shape:Solid
    Molecular weight:440.41
  • Chrysotobibenzyl

    CAS:
    <p>Chrysotobibenzyl from Dendrobium pulchellum stems may trigger cell death in detached cells and hinder lung cancer growth.</p>
    Formula:C19H24O5
    Color and Shape:Solid
    Molecular weight:332.39
  • Hydromethylthionine HBr

    CAS:
    <p>Hydromethylthionine (LMTM/Leucomethylene Blue) inhibits tau in Alzheimer's/frontotemporal dementia and improves brain function.</p>
    Formula:C16H21Br2N3S
    Color and Shape:Solid
    Molecular weight:447.233
  • CHPG

    CAS:
    <p>CHPG is a selective mGluR5 agonist protects against traumatic brain injury.activates the ERK and Akt pathways, It also alleviates LPS-induced inflammation.</p>
    Formula:C8H8ClNO3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:201.61
  • Heat Shock Protein Inhibitor II

    CAS:
    <p>Hsp inhibitor II, an active benzylidene lactam, blocks inducible Hsp synthesis, reduces tumor thermotolerance, and enhances AmB effects on A. fumigatus.</p>
    Formula:C12H11NO3
    Color and Shape:Solid
    Molecular weight:217.22
  • Tau-aggregation-IN-1

    CAS:
    <p>Tau-aggregation-IN-1 is a dopamine D2 and D3 receptor agonist and an inhibitor of tau441 protein aggregation (IC50: 21 μM).</p>
    Formula:C28H37N5O2S
    Color and Shape:Solid
    Molecular weight:507.69
  • AK963

    CAS:
    <p>AK963 (40708899) is a powerful PAK1 inhibitor reducing gastric cancer cell growth via the PAK1-NFκB-CyclinB1 pathway.</p>
    Formula:C16H18N2O
    Color and Shape:Solid
    Molecular weight:254.33
  • (R)-TTBK1-IN-1

    CAS:
    <p>(R)-TTBK1-IN-1: potent, selective brain-penetrant TTBK1 inhibitor, studies Alzheimer’s &amp; tauopathies.</p>
    Formula:C18H19N5O2
    Color and Shape:Solid
    Molecular weight:337.38
  • BMS-688521

    CAS:
    <p>BMS-688521 is an LFA-1/ICAM interaction inhibitor, a small molecule antagonist of LFA-1 with potential anti-inflammatory activity.</p>
    Formula:C26H19Cl2N5O4
    Purity:98.87%
    Color and Shape:Solid
    Molecular weight:536.37
  • Syntelin

    CAS:
    <p>Syntelin: a selective CENP-E inhibitor with an IC50 of 160 nM; distinct from GSK923295, effective on resistant mutants.</p>
    Formula:C21H20N6O2S3
    Color and Shape:Solid
    Molecular weight:484.62
  • LS-104

    CAS:
    <p>LS-104 is a JAK2 inhibitor.</p>
    Formula:C19H16N2O3
    Color and Shape:Solid
    Molecular weight:320.34
  • Tubulin polymerization-IN-25

    CAS:
    <p>Tubulin polymerization-IN-25 inhibits tubulin (IC50: 1.11 μM) &amp; FTase (IC50: 0.39 μM), and is cytotoxic to cancer cells, halting growth.</p>
    Formula:C24H18N2O3S
    Color and Shape:Solid
    Molecular weight:414.48
  • AKT-IN-8

    CAS:
    <p>AKT-IN-8 is a potent inhibitor of AKT, acting on AKT1 (IC50: 4.46 nM), AKT2 (IC50: 2.44 nM) and AKT3 (IC50: 9.47 nM).</p>
    Formula:C22H25ClN6O3
    Color and Shape:Solid
    Molecular weight:456.93
  • AKT-IN-5

    CAS:
    <p>AKT-IN-5, an Akt inhibitor, targets Akt1/Akt2 with IC50s: 450/400 nM.</p>
    Formula:C23H20N4O2
    Color and Shape:Solid
    Molecular weight:384.43
  • Zalunfiban

    CAS:
    <p>RUC-4 is an aIIb 3 antagonist. It is also used for prehospital therapy of myocardial infarction.</p>
    Formula:C16H18N8O2S
    Color and Shape:Solid
    Molecular weight:386.43
  • cemadotin free base

    CAS:
    <p>Cemadotin free base(LU103793 free base) is a novel anti-limiting peptide , an analog of Dolastatin 15, a naturally occurring cytotoxic peptide that blocks</p>
    Formula:C35H56N6O5
    Purity:98.70% - 99.64%
    Color and Shape:Solid
    Molecular weight:640.86
  • Zarilamide

    CAS:
    <p>Zarilamide disrupts microtubules, inhibiting mitosis in Phytophthora capsici zoospore cysts.</p>
    Formula:C11H11ClN2O2
    Color and Shape:Solid
    Molecular weight:238.67
  • Tubulin polymerization-IN-20

    CAS:
    <p>Tubulin aggregation-IN-20, a potent inhibitor, may be studied for breast and drug-resistant colon cancers.</p>
    Formula:C25H24FNO5
    Color and Shape:Solid
    Molecular weight:437.46
  • Tubulin/MMP-IN-1


    <p>Tubulin/MMP-IN-1 inhibits tubulin, MMP, and cancer cell growth; disrupts cell cycles and induces apoptosis.</p>
    Formula:C38H44NO9P
    Color and Shape:Solid
    Molecular weight:689.73
  • HSP90-IN-20

    CAS:
    <p>HSP90-IN-20, a potent inhibitor of HSP90, exhibits an IC50 of ≤10 μM, indicating its potential application in cancer research.</p>
    Formula:C26H32N4O4
    Color and Shape:Solid
    Molecular weight:464.56