Cytoskeletal Signaling
Cytoskeletal signaling inhibitors are compounds that disrupt the signaling pathways regulating the cytoskeleton, which is crucial for cell shape, motility, division, and intracellular transport. These inhibitors are used to study the dynamics of cytoskeletal proteins, such as actin and tubulin, and their role in processes like cell migration, adhesion, and cancer metastasis. Cytoskeletal signaling inhibitors are valuable in research on cell biology, cancer, and neurobiology. At CymitQuimica, we offer a comprehensive range of high-quality cytoskeletal signaling inhibitors to support your research in these areas.
Found 1382 products of "Cytoskeletal Signaling"
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PKC β pseudosubstrate acetate
<p>PKC β pseudosubstrate acetate (PKC β pseudosubstrate acetate (172308-76-8 Free base)) is a selective cell-permeable inhibitor of PKC.</p>Purity:95.42%Color and Shape:SoildBOS-172722
CAS:<p>BOS-172722 is an inhibitor of monopolar spindle 1 (MPS1) checkpoint(IC50 of 2 nM).</p>Formula:C24H30N8OPurity:99.37%Color and Shape:SolidMolecular weight:446.55Bosutinib
CAS:<p>Bosutinib (SKI-606) is a synthetic quinolone derivative and dual kinase inhibitor that targets both Abl (IC50: 1 nM) and Src (IC50: 1.2 nM) kinases.</p>Formula:C26H29Cl2N5O3Purity:98.98% - 99.9%Color and Shape:Yellowish-Orange Or Pink To Brownish Solid Solid PowderMolecular weight:530.45Vedolizumab
CAS:<p>Vedolizumab is a humanized monoclonal antibody that targets the α4β7 integrin for the treatment of Crohn's disease and ulcerative colitis.</p>Purity:SDS-PAGE:98.4%;SEC-HPLC:99.1%Color and Shape:LiquidMolecular weight:146.80 kDaIPI-493
CAS:<p>IPI-493 is a bioactive chemical.</p>Formula:C28H39N3O8Purity:>99.99%Color and Shape:SolidMolecular weight:545.62Akt3 degrader 1
CAS:<p>Akt3 degrader 1 counters Osimertinib resistance in NSCLC, inhibits cell growth, and reduces mouse tumors.</p>Formula:C53H72N8O4Purity:98.12% - 99.02%Color and Shape:SolidMolecular weight:885.19BNC105
CAS:<p>BNC105 is a tubulin polymerization inhibitor. It has potent antiproliferative and tumor vascular disrupting properties.</p>Formula:C20H20O7Purity:96.57%Color and Shape:SolidMolecular weight:372.37N-Desmethyl imatinib
CAS:<p>N-Desmethyl imatinib (Imatinib metabolite N-Desmethyl imatinib) is a metabolite of Imatinib, which is a multi-target inhibitor of c-Kit, v-Abl, and PDGFR.</p>Formula:C28H29N7OPurity:98.60%Color and Shape:Off-White To Pale-Yellow SolidMolecular weight:479.582,3-Butanedione 2-Monoxime
CAS:<p>2,3-Butanedione 2-Monoxime (Diacetyl monoxime) is an inhibitor of skeletal and cardiac muscle contraction.</p>Formula:C4H7NO2Purity:98.62%Color and Shape:Physical Description Cream-Colored Powder (Ntp 1992)Molecular weight:101.1Recilisib
CAS:<p>Recilisib (ON 01210) is a radioprotectant,can activate AKT, PI3K activities in cells.</p>Formula:C16H13ClO4SPurity:98.85% - 98.96%Color and Shape:SolidMolecular weight:336.79Abrilumab
CAS:<p>Abrilumab (MEDI-7183) is a fully human monoclonal antibody against α4β7 that inhibits the α4β7 integrin.</p>Purity:98.5% (SDS-PAGE); 99% (SEC-HPLC) - 98.5% (SDS-PAGE); 99% (SEC-HPLC)Color and Shape:LiquidVerubulin hydrochloride
CAS:<p>Verubulin hydrochloride (MPC-6827 hydrochloride) is an agent of blood brain barrier permeable microtubule-disrupting, with potent and broad-spectrum cytotoxic</p>Formula:C17H18ClN3OPurity:98.29% - 99.77%Color and Shape:SolidMolecular weight:315.8RWJ 50271
CAS:<p>RWJ 50271 inhibits LFA-1/ICAM-1 interaction with IC50 5.0 μM in HL60 cells.</p>Formula:C18H17F3N4O2SPurity:99.09%Color and Shape:SolidMolecular weight:410.41Danicamtiv
CAS:<p>Danicamtiv (MYK-491) is an inotropic agent and it also is a selective allosteric activator of cardiac myosin.</p>Formula:C16H20F3N5O4SPurity:99.38%Color and Shape:SolidMolecular weight:435.42Teplizumab
CAS:<p>Teplizumab (MGA-031) is a humanized monoclonal antibody against CD3 that slows the loss of beta cell function.Teplizumab is used to treat type 1 diabetes.</p>Purity:SDS-PAGE:95.8%;SEC-HPLC:99.7%Color and Shape:LiquidMolecular weight:145.79 kDaFluocinolone (Acetonide)
CAS:<p>Fluocinolone Acetonide (Flucort-N) is a glucocorticoid derivative used topically in the treatment of various skin disorders.</p>Formula:C24H30F2O6Purity:99.29% - 99.82%Color and Shape:Crystals From Acetone & Hexane SolidMolecular weight:452.49ADH-1 trifluoroacetate
CAS:<p>ADH-1 trifluoroacetate (Exherin trifluoroacetate) is a cyclic pentapeptide vascular-targeting agent with potential antineoplastic and antiangiogenic activities.</p>Formula:C24H35F3N8O8S2Purity:90.08% - 99.17%Color and Shape:SolidMolecular weight:684.71Zagotenemab
CAS:<p>Zagotenemab: humanized antibody targeting tau protein to study neurological disorders, including Alzheimer's.</p>Purity:95% - > 95%Color and Shape:LiquidMolecular weight:145.3 kDaAbciximab
CAS:<p>Abciximab: chimeric antibody, anti-platelet, blocks glycoprotein IIb/IIIa, vitronectin, Mac-1.</p>Purity:SDS-PAGE:95.2%;SEC-HPLC:95.9%Color and Shape:LiquidMolecular weight:95.18 kDaImatinib Mesylate
CAS:<p>Imatinib Mesylate (STI-571) is a tyrosine kinase receptor inhibitor with antineoplastic activity (IC50s: 0.6 μM, 0.1 μM and 0.1 μM for v-Abl, c-Kit and PDGFR,</p>Formula:C29H31N7O·CH4SO3Purity:98% - >99.99%Color and Shape:White Crystalline PowderMolecular weight:589.71Dasatinib
CAS:<p>Dasatinib (BMS-354825) is a tyrosine kinase inhibitor that inhibits Src and Bcr-Abl (Ki=16/30 pM) and is orally active and ATP-competitive.</p>Formula:C22H26ClN7O2SPurity:99.59% - 99.86%Color and Shape:Pale-Yellow SolidMolecular weight:488.01Fluorofenidone
CAS:<p>Fluorofenidone (AKF-PD) slows kidney fibrosis by inhibiting NADPH oxidase/ECM via PI3K/Akt, akin to AMR69 but less toxic with a longer half-life.</p>Formula:C12H10FNOPurity:99.85%Color and Shape:SolidMolecular weight:203.21ATN-161 acetate
CAS:<p>ATN-161 acetate, a pentapeptide compound derived from the synergistic region of fibronectin, is an integrin-alpha5 antagonist with antitumor activity.</p>Formula:C25H39N9O10SPurity:98.27%Color and Shape:SoildMolecular weight:657.7CMPD101
CAS:<p>CMPD101 is a membrane-permeable small-molecule inhibitor of GRK2/3 (IC50: 18 nM and 5.4 nM).</p>Formula:C24H21F3N6OPurity:99.01% - 99.04%Color and Shape:SolidMolecular weight:466.46IMAB027
CAS:<p>Naratuximab (Anti-TSPAN26/CD37 Reference Antibody) is a humanized monoclonal antibody against CD37 that can be used to synthesize ADC compounds.</p>Purity:97.7% (SDS-PAGE); 97.5% (SEC-HPLC) - 97.7% (SDS-PAGE); 97.5% (SEC-HPLC)Color and Shape:LiquidMosunetuzumab
CAS:<p>Mosunetuzumab (BCT-4465A) is an IgG1 antibody targeting CD20 & CD3, used for R/R B-NHL and refractory follicular lymphoma.</p>Purity:SDS-PAGE:94.4%;SEC-HPLC:96.1%Color and Shape:LiquidMolecular weight:146.27 kDaAS1949490
CAS:<p>AS1949490, a selective SHIP-2 inhibitor with IC50 of 620 nM, boosts glucose metabolism by upregulating GLUT1 in L6 myotubes.</p>Formula:C20H18ClNO2SPurity:99.94%Color and Shape:SolidMolecular weight:371.88Veltuzumab
CAS:<p>Veltuzumab (IMMU-106) is a humanized anti-CD20 monoclonal antibody that shows anti-proliferative, apoptotic and antibody-dependent cytotoxic effects in vitro.</p>Purity:97.7% (SDS-PAGE); 97.9% (SEC-HPLC) - 97.7% (SDS-PAGE); 97.9% (SEC-HPLC)Color and Shape:LiquidOtelixizumab
CAS:<p>Otelixizumab (ChAglyCD3) is a chimeric monoclonal antibody targeting CD3, used in research on Type 1 diabetes and autoimmune diseases.</p>Purity:>95%Color and Shape:LiquidMeclofenamic acid sodium
CAS:<p>Meclofenamic acid sodium (Movens), a non-steroidal anti-inflammatory agent, has properties of antipyretic and antigranulation activities.</p>Formula:C14H10Cl2NNaO2Purity:98% - 98.96%Color and Shape:SolidMolecular weight:318.14Tubulin inhibitor 6
CAS:<p>Tubulin inhibitor 6 (iHAP1) is an inhibitor of tubulin and a potent inhibitor of multiple cancer cell lines.</p>Formula:C20H14ClNO2SPurity:99.05%Color and Shape:SolidMolecular weight:367.85ALK inhibitor 2
CAS:<p>ALK inhibitor 2 is a new-type and selective inhibitor for the ALK kinase.</p>Formula:C23H28ClN7O3SPurity:99.77% - >99.99%Color and Shape:SolidMolecular weight:518.03Vantictumab
CAS:<p>Vantictumab (OMP-18R5) is a humanized anti-FZD1/2/5/7/8 monoclonal antibody that inhibits Wnt pathway signaling.</p>Purity:99% (SDS-PAGE); 97.7% (SEC-HPLC) - 99% (SDS-PAGE); 97.7% (SEC-HPLC)Color and Shape:LiquidDonanemab
CAS:<p>Donanemab (LY3002813), a humanized IgG1 antibody, targets N-terminal Aβ for potential early Alzheimer's research.</p>Purity:95%Color and Shape:LiquidPamidronate Disodium
CAS:<p>Pamidronate Disodium (CGP 23339A), a nitrogen-containing bisphosphonate, can help to strengthen bones.</p>Formula:C3H9NNa2O7P2Purity:99.86% - 99.93%Color and Shape:White CrystalsMolecular weight:279.03Gantofiban
CAS:<p>Gantofiban is a glycoprotein IIb/IIIa (GP IIb/IIIa) antagonist used in the treatment of cardiovascular disease and may be used to study thrombosis.</p>Formula:C21H29N5O6Purity:99.57%Color and Shape:SolidMolecular weight:447.48GRGDSP
CAS:<p>Gly-Arg-Gly-Asp-Ser-Pro (GRGDSP) is used as a soluble integrin-blocking RGD-based peptide.</p>Formula:C22H37N9O10Purity:98%Color and Shape:SolidMolecular weight:587.58Larazotide
CAS:<p>Larazotide: octapeptide from V. cholerae, treats Coeliac disease by inhibiting paracellular permeability.</p>Formula:C32H55N9O10Purity:98%Color and Shape:SolidMolecular weight:725.83DSPE-PEG2000-cRGD
<p>DSPE-PEG2000-cRGD is a PEG compound composed of DSPE and an αvβ3-targeting peptide (cRGD). The cRGD peptide specifically binds to αvβ3 on the surface of various cancer cells and neovascular cells. This compound can be utilized for drug delivery.</p>Color and Shape:Odour SolidPDS-0330
CAS:<p>PDS-0330, a claudin-1 inhibitor, hinders CRC growth and metastasis with micromolar affinity and promising pharmacokinetics.</p>Formula:C25H17N3O2SPurity:99.93%Color and Shape:SoildMolecular weight:423.49hCA/Wnt/β-catenin-IN-1
<p>hCA/Wnt/β-catenin-IN-1 (Compd 15) serves as an inhibitor with selective affinity for hCA isoforms II, IX, and XII, exhibiting K i values of 33.6, 24.1, and 6.8</p>Color and Shape:Odour SolidTubulin polymerization-IN-46
<p>Tubulin polymerization-IN-46 (compound 9q) is a microtubule/tubulin inhibitor that impedes tubulin polymerization, induces apoptosis, and arrests MCF-7 breast</p>Formula:C22H25NO6Color and Shape:SolidMolecular weight:399.44DSPE-PEG2000-iRGD
<p>DSPE-PEG2000-iRGD is a PEG compound composed of DSPE and the αv-integrin targeting peptide (iRGD). The iRGD peptide binds to αv-integrins and subsequently undergoes proteolytic cleavage within tumors, producing CRGDK/R, which interacts with neuropilin-1. This compound is characterized by its tumor-targeting and tumor-penetrating properties, making DSPE-PEG2000-iRGD suitable for drug delivery applications.</p>Color and Shape:Odour SolidSNIPER(ABL)-013
<p>SNIPER(ABL)-013, a compound that links GNF5 (ABL inhibitor) with Bestatin (IAP ligand) via a linker, effectively reduces BCR-ABL protein levels with a DC50 of</p>Formula:C42H52F3N7O8Purity:98%Color and Shape:SolidMolecular weight:839.9Epothilone F
CAS:<p>Epothilone F, an active metabolite of Epothilone D with a hydroxymethyl on thiazole, disrupts cell division, shows promise over taxanes, and is water-soluble.</p>Formula:C27H41NO7SColor and Shape:SolidMolecular weight:523.68Zolbetuximab MMAE
<p>Zolbetuximab MMAE (IMAB362 MMAE) is a compound targeting Claudin 18.2 (CLDN18.2) with anti-cancer activity, used in the study of gastric and pancreatic cancers.</p>Purity:95% - 95%Color and Shape:LiquidMolecular weight:150 kDahAChE-IN-1
<p>hAChE-IN-1 (Compound 24) is a potent inhibitor of human acetylcholinesterase (hAChE), exhibiting an inhibition concentration half-maximum (IC50) of 1.09 μM.</p>Formula:C22H24N4OColor and Shape:SolidMolecular weight:360.45Foxy-5
CAS:<p>Foxy-5 is a wnt5a peptide mimetic</p>Formula:C26H42N6O12S2Purity:98%Color and Shape:SolidMolecular weight:694.776BrCaQ-C10-TPP
<p>6BrCaQ-C10-TPP inhibits TRAP1, halts cancer cell growth (IC50=0.008-0.30µM), disrupts mitochondrial membrane.</p>Formula:C45H47Br2N2O3PColor and Shape:SolidMolecular weight:854.65trans-Dehydrocurvularin
CAS:<p>trans-Dehydrocurvularin is a useful organic compound for research related to life sciences. The catalog number is T125357 and the CAS number is 21178-57-4.</p>Formula:C16H18O5Color and Shape:SolidMolecular weight:290.315
