Cytoskeletal Signaling
Cytoskeletal signaling inhibitors are compounds that disrupt the signaling pathways regulating the cytoskeleton, which is crucial for cell shape, motility, division, and intracellular transport. These inhibitors are used to study the dynamics of cytoskeletal proteins, such as actin and tubulin, and their role in processes like cell migration, adhesion, and cancer metastasis. Cytoskeletal signaling inhibitors are valuable in research on cell biology, cancer, and neurobiology. At CymitQuimica, we offer a comprehensive range of high-quality cytoskeletal signaling inhibitors to support your research in these areas.
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Lifitegrast
CAS:1025967-78-5
Lifitegrast (SAR 1118) is a lymphocyte, function-associated antigen-1 antagonist.
Formula:
C29H24Cl2N2O7S
Purity:
99.39% - 99.66%
Color and Shape:
Solid
Molecular weight:
615.48
Ref: TM-T3977
| 5mg | 39.00 € | ||
| 10mg | 57.00 € | ||
| 25mg | 92.00 € | ||
| 50mg | 144.00 € | ||
| 100mg | 227.00 € | ||
| 500mg | 558.00 € | ||
| 1mL*10mM (DMSO) | 60.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
PF-562271
CAS:717907-75-0
PF-562271 is an effective ATP-competitive, reversible inhibitor of FAK(IC50=1.5 nM) and Pyk2 kinase(IC50=13 nM).
Formula:
C21H20F3N7O3S
Purity:
100% - 97.65%
Color and Shape:
Solid
Molecular weight:
507.49
Ref: TM-T2465
| 1mg | 59.00 € | ||
| 5mg | 127.00 € | ||
| 10mg | 159.00 € | ||
| 25mg | 259.00 € | ||
| 50mg | 378.00 € | ||
| 100mg | 567.00 € | ||
| 500mg | 1,188.00 € | ||
| 1mL*10mM (DMSO) | 140.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
Daphnetin
CAS:486-35-1
Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR …
Formula:
C9H6O4
Purity:
98.33% - 99.82%
Color and Shape:
Solid
Molecular weight:
178.14
Ref: TM-T2851
| 10mg | 50.00 € | ||
| 25mg | 95.00 € | ||
| 50mg | 166.00 € | ||
| 100mg | 244.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
S-trityl-L-Cysteine
CAS:2799-07-7
S-trityl-L-Cysteine is a potent inhibitor of human mitotic kinesin Eg5
Formula:
C22H21NO2S
Purity:
97.02%
Color and Shape:
Almost White To Light Yellow Granular Powder
Molecular weight:
363.47
Ref: TM-T36816
| 25mg | 35.00 € | ||
| 50mg | 47.00 € | ||
| 100mg | 60.00 € | ||
| 200mg | 88.00 € | ||
| 500mg | 131.00 € | ||
| 1mL*10mM (DMSO) | 47.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
Suprafenacine
CAS:1477482-50-0
Suprafenacine (N'-[(E)-(4-methylphenyl)methylidene]-4,5,6,7-tetrahydro-1H-indazole-3-carbohydrazide) is a cell-permeable microtubule destabilizer that induces
Formula:
C16H18N4O
Purity:
99.72%
Color and Shape:
Solid
Molecular weight:
282.34
Ref: TM-T28886
| 1mg | 64.00 € | ||
| 2mg | 89.00 € | ||
| 5mg | 131.00 € | ||
| 10mg | 178.00 € | ||
| 25mg | 321.00 € | ||
| 50mg | 452.00 € | ||
| 100mg | 638.00 € | ||
| 200mg | 843.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
PF-AKT400
CAS:1004990-28-6
PF-AKT400 (AKT protein kinase inhibitor) is a broadly selective and ATP-competitive inhibitor of Akt.
Formula:
C20H22F2N6O
Purity:
98.21%
Color and Shape:
Solid
Molecular weight:
400.43
Ref: TM-T5508
| 1mg | 95.00 € | ||
| 5mg | 227.00 € | ||
| 10mg | 325.00 € | ||
| 25mg | 550.00 € | ||
| 50mg | 787.00 € | ||
| 100mg | 1,093.00 € | ||
| 1mL*10mM (DMSO) | 250.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
GMB-475
CAS:2490599-18-1
GMB-475, a PROTAC-based BCR-ABL1 inhibitor, tackles drug resistance by promoting VHL-mediated degradation.
Formula:
C43H46F3N7O7S
Purity:
100% - 98.78%
Color and Shape:
Solid
Molecular weight:
861.93
Ref: TM-T8488
| 1mg | 96.00 € | ||
| 5mg | 200.00 € | ||
| 10mg | 350.00 € | ||
| 25mg | 590.00 € | ||
| 50mg | 840.00 € | ||
| 100mg | 1,130.00 € | ||
| 500mg | 2,308.00 € | ||
| 1mL*10mM (DMSO) | 274.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
Chelerythrine
CAS:34316-15-9
1.
Formula:
C21H18NO4
Purity:
98.36%
Color and Shape:
Solid
Molecular weight:
348.37
Ref: TM-T6S0052
| 5mg | 55.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 142.00 € | ||
| 50mg | 207.00 € | ||
| 100mg | 309.00 € | ||
| 1mL*10mM (DMSO) | 80.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
CW-069
CAS:1594094-64-0
CW-069 (IC50=75 μM), an allosteric selective inhibitor of microtubule motor protein HSET, exhibits remarkable specificity …
Formula:
C23H21IN2O3
Purity:
97.52% - 98.59%
Color and Shape:
Solid
Molecular weight:
500.33
Ref: TM-T6209
| 1mg | 43.00 € | ||
| 5mg | 90.00 € | ||
| 10mg | 125.00 € | ||
| 25mg | 216.00 € | ||
| 50mg | 306.00 € | ||
| 100mg | 432.00 € | ||
| 500mg | 938.00 € | ||
| 1mL*10mM (DMSO) | 89.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
KW-2449
CAS:1000669-72-6
KW-2449 is a multiple-targeted inhibitor, mostly for Flt3, modestly effective to Bcr-Abl, FGFR1, and Aurora …
Formula:
C20H20N4O
Purity:
98.43% - 99.89%
Color and Shape:
Solid
Molecular weight:
332.4
Ref: TM-T2341
| 2mg | 39.00 € | ||
| 5mg | 57.00 € | ||
| 10mg | 79.00 € | ||
| 25mg | 145.00 € | ||
| 50mg | 259.00 € | ||
| 100mg | 482.00 € | ||
| 500mg | 1,074.00 € | ||
| 1mL*10mM (DMSO) | 59.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
4-Isopropoxybenzoic acid
CAS:13205-46-4
4-Isopropoxybenzoic acid (AI3 12104) is a Centromere-Associated Protein E inhibitor.
Formula:
C10H12O3
Purity:
98.58%
Color and Shape:
White To Off-White Powder
Molecular weight:
180.2
Ref: TM-T24977
| 10mg | 40.00 € | ||
| 25mg | 65.00 € | ||
| 50mg | 90.00 € | ||
| 100mg | 117.00 € | ||
| 200mg | 170.00 € | ||
| 1mL*10mM (DMSO) | 34.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
AMP-945
CAS:1393653-34-3
AMP-945 is a proprietary focal adhesion kinase (FAK) inhibitor.
Formula:
C28H32F3N5O2
Purity:
99.60%
Color and Shape:
Solid
Molecular weight:
527.58
Ref: TM-T9576
| 1mg | 97.00 € | ||
| 5mg | 188.00 € | ||
| 10mg | 311.00 € | ||
| 25mg | 533.00 € | ||
| 50mg | 755.00 € | ||
| 100mg | 1,035.00 € | ||
| 1mL*10mM (DMSO) | 254.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
Gap19
CAS:1507930-57-5
Gap19 is a peptide that corresponds to a sequence on the cytoplasmic loop (CL) of …
Formula:
C55H96N14O13
Purity:
97.67%
Color and Shape:
Solid
Molecular weight:
1161.44
Ref: TM-TP1563
| 1mg | 57.00 € | ||
| 2mg | 84.00 € | ||
| 5mg | 123.00 € | ||
| 10mg | 185.00 € | ||
| 25mg | 359.00 € | ||
| 50mg | 525.00 € | ||
| 100mg | 747.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
Estramustine
CAS:2998-57-4
Estramustine (LEO-275), a nitrogen mustard-estradiol compound, treats prostate cancer and protects against radiation.
Formula:
C23H31Cl2NO3
Purity:
99.25%
Color and Shape:
Solid
Molecular weight:
440.4
Ref: TM-T20681
| 5mg | 47.00 € | ||
| 10mg | 70.00 € | ||
| 25mg | 126.00 € | ||
| 50mg | 202.00 € | ||
| 100mg | 329.00 € | ||
| 500mg | 783.00 € | ||
| 1mL*10mM (DMSO) | 57.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
BGG463
CAS:890129-26-7
BGG463 (K 0859) can inhibit c-ABL-T334I, BCR-ABL and BCR-ABL-T315I variants with an IC50 of 0.25 …
Formula:
C30H29F3N6O3
Purity:
100% - 95.05%
Color and Shape:
Solid
Molecular weight:
578.58
Ref: TM-T4618
| 1mg | 62.00 € | ||
| 2mg | 87.00 € | ||
| 5mg | 119.00 € | ||
| 10mg | 188.00 € | ||
| 25mg | 350.00 € | ||
| 50mg | 505.00 € | ||
| 100mg | 730.00 € | ||
| 1mL*10mM (DMSO) | 154.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
BIIB021
CAS:848695-25-0
BIIB021 (CNF2024) is an orally-available, fully synthetic inhibitor of HSP90(Ki=1.7 nM, EC50=38 nM).
Formula:
C14H15ClN6O
Purity:
98% - 99.82%
Color and Shape:
Solid
Molecular weight:
318.76
Ref: TM-T2286
| 5mg | 52.00 € | ||
| 10mg | 74.00 € | ||
| 25mg | 106.00 € | ||
| 50mg | 170.00 € | ||
| 100mg | 250.00 € | ||
| 200mg | 427.00 € | ||
| 500mg | 705.00 € | ||
| 1mL*10mM (DMSO) | 57.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
ML346
CAS:100872-83-1
ML346 is a novel activator of Hsp70.
Formula:
C14H12N2O4
Purity:
99.25% - 99.29%
Color and Shape:
Solid
Molecular weight:
272.26
Ref: TM-T3594
| 1mg | 40.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 85.00 € | ||
| 10mg | 115.00 € | ||
| 25mg | 172.00 € | ||
| 50mg | 274.00 € | ||
| 100mg | 427.00 € | ||
| 500mg | 938.00 € | ||
| 1mL*10mM (DMSO) | 85.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
PD173955
CAS:260415-63-2
PD173955 is src family-selective tyrosine kinase inhibitor with IC50 of ~22 nM for Src, Yes …
Formula:
C21H16Cl2N4OS
Purity:
98.52% - 99.28%
Color and Shape:
Solid
Molecular weight:
443.35
Ref: TM-T3063
| 1mg | 48.00 € | ||
| 5mg | 88.00 € | ||
| 10mg | 144.00 € | ||
| 25mg | 283.00 € | ||
| 50mg | 437.00 € | ||
| 100mg | 655.00 € | ||
| 1mL*10mM (DMSO) | 163.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
TRC051384
CAS:867164-40-7
TRC051384 is a HSP70 inducer that reduces stroke-associated neuronal damage and increases survival in a …
Formula:
C25H31N5O4
Purity:
92.66%
Color and Shape:
Solid
Molecular weight:
465.54
Ref: TM-T3527
| 1mg | 37.00 € | ||
| 5mg | 80.00 € | ||
| 10mg | 111.00 € | ||
| 25mg | 210.00 € | ||
| 50mg | 298.00 € | ||
| 100mg | 432.00 € | ||
| 200mg | 622.00 € | ||
| 1mL*10mM (DMSO) | 81.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
AG1024
CAS:65678-07-1
AG1024 (Tyrphostin) suppresses IGF-1R autophosphorylation(IC50=7 μM), and is less potent for IR(IC50=57 μM).
Formula:
C14H13BrN2O
Purity:
98% - 99.37%
Color and Shape:
Solid
Molecular weight:
305.17
Ref: TM-T2693
| 2mg | 40.00 € | ||
| 5mg | 57.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 160.00 € | ||
| 50mg | 235.00 € | ||
| 100mg | 354.00 € | ||
| 1mL*10mM (DMSO) | 64.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
