Deuterated Compounds

Applications Isotope labelled Trimethylsilyl Cyanide (T796750) is used as a reagent in the synthesis of optically active cyanohydrins. Used in the preparation of Reissert compounds, which represent reactive polyamides. Toxic to humans.
References Roberge, C. et al.: Tetrahedron Asymm., 18, 208 (2007); Jois, Y. et al.: Macromol., 26, 6151 (1993); Lumor, S. et al.: J. Food. Sci., 76, T16 (2011);

Applications 2-Iodopropane-2-d1 (CAS# 95927-03-0) is a useful isotopically labeled research compound.

Applications iso-Propylamine-d9 (CAS# 1219794-73-6) is a useful isotopically labeled research compound.

Applications Ethyl-alpha,alpha-d2-benzene-d5 (CAS# 84272-90-2) is a useful isotopically labeled research compound.

Applications Isotope labelled tert-Butylbenzene is a component of the model diesel fuel.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Xiao, Jing, et al.: Indus. & Eng. Chem. Res., 51(8), 3436-3443 (2012)

Applications tert-Butyl-d9 Acrylate (CAS# 928163-00-2) is a useful isotopically labeled research compound.

Applications 17beta-Dihydroequilin-2,4,16,16-d4 (CAS# 350819-99-7) is a useful isotopically labeled research compound.

Applications N-Suberylglycine-2,2-d2 (CAS# 1219799-02-6) is a useful isotopically labeled research compound.

Applications Glyceryl-d5 Trihexadecanoate (CAS# 60763-98-6) is a useful isotopically labeled research compound.

Applications 2,4,6-Trimethylbenzeneamine-d11 (cas# 1126138-13-3) is a compound useful in organic synthesis.

Applications 4-Fluorobenzyl-d6 Alcohol (CAS# 1071809-48-7) is a useful isotopically labeled research compound.

Applications Methylcycloheptane-d3 is the isotope analog of Methylcycloheptane. It is synthesized form cycloheptanone (C989555), which is a common reagent used as the precursor for the synthesis of various pharmaceuticals including NF-κB-inducing kinase inhibitor.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Li, K., et al.: Bioorg. Med. Chem. Lett., 23, 1238 (2013); Hayden, M., et al.: Cell, 132, 344 (2008); Mackay, F., et al.: Annu. Rev. Immunol., 21, 231 (2003)

Applications 2,3-Dichlorobenzoic-d3 Acid (CAS# 1126107-18-3) is a useful isotopically labeled research compound.

Applications 5-Bromo-2,4-pyrimidinedione-13C,15N2 is the isotope labelled analogue of Bromouracil, a halogenated nitrogenous base on RNA nucleosides.
References Morinaga, H., et al.: Bioorg. Med. Chem., 21, 466 (2013);

Applications Carcinogenic compound commonly found in hair dyes and henna ink, also a commonly used synthetic intermediate
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Mulyono; T., et al.: J. Biosci. Bioeng., 103, 147 (2007), Mosley-Foreman, C., et al.: Food Chem. Toxicol., 46, 3780 (2008), Patel, A.K., et al.: J. Agric. Food Chem., 56, 9236 (2008), Akyuz, M., et al.: J. Pharm. Biomed. Anal., 47, 68 (2008),

Applications Labelled Cortisol-d4 21-Sulfate (C696320). Cortisol 21-Sulfate is a phase II metabolite of Cortisol (H714615).
References Spielgelhalder, B., et al.: J. Steroid Biochem., 7, 749 (1976), Vanluchene, E., et al.: J. Chromatogr., 456, 175 (1988), Choi, M., et al.: Steroids, 65, 54 (2000),

Applications Choline-d9 Bromide (N,N,N-trimethyl-d9) (CAS# 285979-71-7) is a useful isotopically labeled research compound.

Applications 4-Fluorobenzyl-2,3,5,6-d4-amine (CAS# 1219798-96-5) is a useful isotopically labeled research compound.

Applications n-Tetracontane-d82 (CAS# 1219802-99-9) is a useful isotopically labeled research compound.

Applications Isobutylsuccinic Acid-d9 is labelled Isobutylsuccinic Acid (I780660) which was used to synthesize succinimide derivatives as inhibitors of human leukocyte elastase, cathepsin G and proteinase 3.
References Groutas, W., et al.: Bioorg. Med. Chem., 3, 375 (1995);

Applications 1-Iodopropane-1,1-d2 (CAS# 25493-14-5) is a useful isotopically labeled research compound.

Stability Volatile
Applications Isotope labelled Acetonitrile is used as a polar aprotic solvent in organic synthesis.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Hu, H.H., et al.: Phy. Chem. Phys., 15, 7666 (2013); Kim, J.Y., et al.: J. Mater. Chem. A., et al.: 1, 5982 (2013);

Applications n-Butylamine-ND2 DCl (CAS# 156235-87-9) is a useful isotopically labeled research compound.
Chemical Name: n-Butylamine-ND2 DCl (CAS# 156235-87-9) is a useful isotopically labeled research compound.

Applications 1-(2-Ethoxy-2-oxoethyl)pyridin-1-ium-d5 Chloride is an intermediate used in the synthesis of Girard’s Reagent P-d5 (G388502), which is a labeled girard’s reagent used in the identification and quantification of protein carbonylation as well as in the modification of nucleosides and nucleotides. Used in the preparation of potent photoactive agents.
References Mirzaei, H. et al.: J. Chrom. A, 1134, 122 (2007); Kanofsky, J.R. et al.: Photochem. Photobiol., 73, 349 (2001);

Applications Acetamide-d5 (CAS# 33675-83-1) is a useful isotopically labeled research compound.

Applications 1-Bromooctane-3,3,4,4-d4 (CAS# 1219803-37-8) is a useful isotopically labeled research compound.

Applications N-Methyl Lacosamide-d3 is the labeled analogue of N-Methyl Lacosamide (M315210), a methly analogue of Lacosamide (L098500), a medication used for the adjunctive treatment of partial-onset seizures and diabetic neuropathic pain. Lacosamide is a potent anticonvulsant.
References Lees, G., et al.: Brain Res., 612, 190 (1993), Kuo, C., et al.: Mol. Pharmacol., 51, 1077 (1997); Barton, M., et al.: Epilepsy Res., 47, 217 (2001); Beyreuther, B., et al.: Eur. J. Pharmacol., 539, 64 (2006); Beyreuther, B., et al.: CNS Drug Rev., 13, 21 (2007)

Applications 1-[5-Chloro-2-(2,4-dichlorophenoxy)phenylethanone]-d2 Major (cas# 1189477-14-2) is a compound useful in organic synthesis.

Applications (4S)-6-Chloro-4-(2-cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazine-d2 ,13C1, is the labeled analogue of (4S)-6-Chloro-4-(2-cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazine (C365935), used for the synthesis of Efavirenz (E425000), which is a nonnucleoside HIV-1 reverse transcriptase inhibitor.
References Young, S.D., et al.: Antimicrob. Ag. Chemother., 39, 2602 (1995),

Applications 4-Chlorobenzyl-2,3,5,6-d4 Cyanide (CAS# 1219804-00-8) is a useful isotopically labeled research compound.

Applications Pentachlorothioanisole-13C6, is the labeled analogue of Pentachlorothioanisole (P238170), which can be used in the preparation of arenethiols and arenethiolates as seen in agrochemicals or fungicides.
References Dulik, D. et al.: Xenobiotica, 22, 325 (1992); Rakitin, O. et al.: Sci. Synth., 31a, 949 (2007);

Applications Lombazole-d9 is deuterium labelled form of Lombazole (L470205), which is imidazole based antimicrobial agent with some antifungal activity.
References Barug, D., De Groot, K.: Antimicrob. Agents Chemother., 28, 643 (1985); Barug, D., et al.: Antimicrob. Agents Chemother., 30, 238 (1986);

Applications Styrene-alpha,beta,beta-d3 (CAS# 3814-93-5) is a useful isotopically labeled research compound.

Applications 2-Phenylpropane-1,1,1,3,3,3-d6 (CAS# 20201-29-0) is a useful isotopically labeled research compound.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications 2,2-Dimethyloctanoic Acid-d3 is the isotope analog of 2,2-Dimethyloctanoic Acid. 2,2-Dimethyloctanoic Acid is used in biological studies as benzyl dimethyloctanoate metabolite of sewage bacteria.
References Millier, A., et al.: Bull. Environ. Contam. Toxicol., 28, 113 (1982);

Applications Ethylene Glycol Monooctanoate-d4 is a deuterated version of Ethylene Glycol Monooctanoate (E917547), a reactant in the synthesis of water-woluble phospholipid analogues as inhibitors of phospholipase C.
References Franklin, Christopher L., et al.: J. of Org. Chem., 68(19), 7298-7307 (2003)

Applications Ethylbenzene-2,3,4,5,6-d5 (CAS# 20302-26-5) is a useful isotopically labeled research compound.

Applications Glyceryl Tri(pentadecanoate-d29) (CAS# 352431-43-7) is a useful isotopically labeled research compound.

Applications (±)-2-Chloropropionyl-2,3,3,3-d4 Chloride (CAS# 1219794-98-5) is a useful isotopically labeled research compound.

Stability Volatile
Applications rac 1,2-Diaminopropane-d3 is labelled rac 1,2-Diaminopropane which was used as model precursor in the electron induced deposition of amorphous carbon nitride films. It was also used to synthesize cage peroxide, 1,6-diaza-3,4,8,9-tetraoxa-11-methylbicyclo[4.4.2]dodecane.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Wnuk, J., et al.: J. Phys. Chem., 113, 12345 (2009); Edward, J., et al.: Can. J. Chem., 77, 1057 (1999)

Applications 1,4-Cyclohexane-d10-diamine (cis/trans mixture) (CAS# 1219802-80-8) is a useful isotopically labeled research compound.

Applications Labelled Isopentenyl Pyrophosphate. Used for the preparation of antitumor agents phosphohalohydrins.
References Dhe-Paganon, S., et al.: Biochem., 33, 13355 (1994), Tanaka, Y., et al.: Nature, 375 155 (1995), Wesch, D., et al.: Eur. J. Immunol., 27, 952 (1997),

Applications Dodecylphosphocholine (D38, 98%) (cas# 130890-78-7) is a useful research chemical.

Applications N,N-Bis-desethyl, N-Methyl Entacapone-d3 is the isotope analog of N,N-Bis-desethyl, N-Methyl Entacapone which is an impurity of Entacapone (E558500). The (E)-Isomer of Entacapone which is a polymorphic form A. Peripherally acting inhibitor of catechol-O-methyl transferase (COMT), an enzyme involved in the metabolism of catecholamine neurotransmitters and related drugs. Antiparkinsonian.
References Karlsson, M., et al.: J. Pharm. Biomed. Anal., 10, 593 (1992), Nissinen, E., et al.: Arch. Pharmacol., 346, 262 (1992), Wikberg, T., et al.: Eur. J. Drug Metab. Pharmacokinet., 18, 359 (1993),

Applications Hexadecanoic-15,15,16,16,16-d5 Acid (CAS# 285979-77-3) is a useful isotopically labeled research compound.

Applications Labelled 2,4-Diaminobutyric Acid. 2,4-Diaminobutyric Acid is a pharmacological tool and potential chiral building block. 2,4-Diaminobutyric Acid is also used as an internal standard for amino acid analysis. 2,4-Diaminobutyric Acid is also found to inhibit GABA transaminase, thus producing an elevation of GABA level, and to have an antitumor activity in vitro and in vivo against mouse fibrosarcoma cells.
References Riordan, J.F. et al.: Methods Enzymol., 47, 31 (1977); Beart, P.M. et al.: Neurscience Lett., 5, 193 (1977); Ronquist, G. et al.: J. Cancer Res. Clin. Oncol., 96, 259 (1980); Solladie-Cavallo, A. et al.: Tetrahedron Lett., 30, 6011 (1989);

Applications (3,4,5-Trimethoxyphenyl)acetic-alpha,alpha-d2 Acid (CAS# 344299-45-2) is a useful isotopically labeled research compound.

Applications Potassium Dodecanoate-d23 (CAS# 51732-20-8) is a useful isotopically labeled research compound.

Stability Volatile
Applications Acetonitrile (15n, 98%+) (cas# 14149-39-4) is a useful research chemical.

Applications 2,6-Dimethylnaphthalene-d12 (CAS# 350820-12-1) is a useful isotopically labeled research compound.

Applications Labelled Indole derivative with anticancer activity.
References Lavrenov, S. et al.: Bioorgan. Med. Chem. 18, 6905 (2010)

Applications Phosphoric Acid-D4 Trifluoroboroane Deuterium Oxide is an intermediate in the synthesis of 3-Hydroxy Benzopyrene-d11 (H829402), which is a abelled metabolite of Benzopyrene (BaP), a carcinogenic component of tobacco smoke implicated in lung cancer.
References DiBiasio, K., et al.: Drug Metab. Dispos.,19, 227 (1991), Beach, J., et al.: J. Anal. Toxicol., 24, 670 (2000), Borman, S., et al.: Toxicol. Appl. Pharmacol., 167, 191 (2000), Tsai-Turton, M., et al.: Biol. Reprod., 77, 442 (2007),

Applications 2-Nitrobiphenyl-d9 (CAS# 38537-53-0) is a useful isotopically labeled research compound.

Applications (±)-Ropivacaine-d7 (propyl-d7) (CAS# 1392208-04-6) is a useful isotopically labeled research compound.

Applications 4-Hydroxypiperidine-3,3,4,5,5-d5 (CAS# 1219799-35-5) is a useful isotopically labeled research compound.

Applications (1,2,5,6-Tetramethyl-d6)naphthalene is the labeled analogue of 1,2,5,6-Tetramethylnaphthalene (T303675), a polycyclic aromatic hydrocarbon that has been found in petroleum.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Forster, P.G., et. al.: J. Chromatogr., 483, 384 (1989)

Applications Ethyl N-n-Butyl-d9-carbamate (CAS# 1276197-24-0) is a useful isotopically labeled research compound.

Applications (2,4-Dichlorophenoxy-d3)acetic-d2 Acid (CAS# 352438-69-8) is a useful isotopically labeled research compound.

Applications N-Methylform-d1-amide (CAS# 26103-38-8) is a useful isotopically labeled research compound.

Applications Tetradecanoic-14,14,14-d3 Acid (CAS# 62217-71-4) is a useful isotopically labeled research compound.

Applications Methyl Methacrylate-d5 (CAS# 55935-46-1) is a useful isotopically labeled research compound.

Applications Reagent used in the addition of labelled cyclopropane.