Deuterated Compounds

Stability Hygroscopic
Applications Lauroyl-L-carnitine-d3 Hydrochloride is labelled Lauroyl-L-carnitine (L178680) which is a long-chain fatty ester of carnitine which is accumulated and released into the circulation, in fatty-acid oxidation defects. Pattern of Lauroyl-L-carnitine can be diagnostic for a number of ß-oxidation defects.
References Ventura, F., et al.: Clinica Chimica Acta, 281, 1 (1999); Pourfarzam, M., et al.: Clinical Chem,, 40, 2267 (1994); Schaefer, J., et al.: Pediatric Res., 37, 354 (1995)

Applications Thymine-alpha,alpha,alpha,6-d4 Glycol (mixture of diastereomers) (CAS# 132523-94-5) is a useful isotopically labeled research compound.

Applications 3-Pyridylcarbinol-d6 (cas# 1189493-62-6) is a compound useful in organic synthesis.

Applications n-Butyl-1,1,2,2,3,3-d6 Alcohol (CAS# 1219794-84-9) is a useful isotopically labeled research compound.

Applications labelled 5-Methyl-3-heptanol.

Applications Bis(o-cresyl) p-Cresyl Phosphate-d7 is labelled Bis(o-cresyl) p-Cresyl Phosphate (B419205), an isomer of Tricresyl phosphate (TCP) which is used as an anti-wear additive in aircraft turbine engine oil.
References De Nola, G., et al.: J. Chrmoat. A, 1200, 211 (2008)

Applications cis-7,10,13,16-Docosatetraenoic Acid Methyl Ester-d3 is a labelled analog of cis-7,10,13,16-Docosatetraenoic Acid Methyl Ester. cis-7,10,13,16-Docosatetraenoic Acid Methyl Ester is used in oregano essential oil as an inhibitor of higher fatty acid oxidation.
References Terenina, M.B., et al.: Appl. Biochem. Microbiol., 47, 445 (2011)

Applications Diethyl Chlorothiophosphate-d10 (cas# 287397-89-1) is a compound useful in organic synthesis.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications trans-4-Fluoropyrrolidine-2-carboxylic Acid-13C1 Hydrochloride Salt is an isotopic analog of (2S,4R)-4-Fluoropyrrolidine-2-carboxylic Acid (F594640).

Applications 3,3’-((2-Hydroxypropane-1,3-diyl)bis(oxy))bis(2-(3-ethoxy-3-oxopropanoyl)phenolate) Disodium Salt-d5 is an intermediate used in the synthesis of Cromolyn-d5 Disodium Salt (C815002), which is a chromone complex which blocks mast cell degranulation.
References Ashton, M.J., et al.: Toxicol. Appl. Pharmacol., 26, 319 (1973), Friday, G.A., et al.: Am. J. Ophthalmol., 95, 169 (1983)

Applications Labelled Sarmentine (S141600). Sarmentine is used for controlling plant pests.
References Alecio, A., et al.: J. Na.t Prod., 61, 637 (1998), Duh, C., et al.: J. Nat. Prod., 53, 1575 (1990), Yang, Y., et al.: J. Agric. Food Chem., 50, 3765 (2002), Tsai, I., et al.: Planta Med., 71, 535 (2005),

Applications 1,3,5-Trimethylbenzene-2,4,6-d3 (CAS# 38574-14-0) is a useful isotopically labeled research compound.

Applications L-Aspartic Acid (13c4, 99%; 15n, 99%) (cas# 202468-27-7) is a useful research chemical.

Applications 1,12-Dibromododecane-d24 (CAS# 1044544-84-4) is a useful isotopically labeled research compound.

Applications Hexadecanoic-4,4-d2 Acid (CAS# 30719-28-9) is a useful isotopically labeled research compound.

Applications 16-COOH Mitragynine - D3 is the labeled 16-COOH Mitragynine(C724820) which is a derivative of Mitragynine(M373550) which is a neurochemical, having both stimulant and opiate-like effects depending on the dosage. Currently, Mitragynine is being investigated for its ability to treat hard drug addiction.
References Kikura-Hanajiri, R., et al.: For. Toxicol., 27, 67 (2009); Bjoernstad, K., et al.: Clin. Toxicol., 47, 566 (2009); Parthasarathy, S., et al.: Anal. Bioanal. Chem., 397, 2023 (2010);

Applications (±)-Tetrahydro-2-furoic-d7 Acid (CAS# 1219798-42-1) is a useful isotopically labeled research compound.

Applications 1,9-Dibromononane-d18 (CAS# 150017-89-3) is a useful isotopically labeled research compound.

Applications Cyclopropyl-1-d1 Methyl-d3 Ketone (CAS# 95249-93-7) is a useful isotopically labeled research compound.

Applications N-[(2E)-6,6-Dimethyl-2-hepten-4-yn-1-yl]-N-methyl-2-naphthalenemethanamine-d3 hydrochloride is an labelled impurity of Terbinafine (T107500), an orally active, antimycotic allylamine and a specific inhibitor of squalene epoxidase.
References Petranyi, G., et al.: Science, 224, 1239 (1984); Ryder, N.S., et al.: Antimicrob. Agents Chemother., 27, 252 (1985); Evans, E.G.V., et al.: Br. Med. J., 318, 1031 (1999);

Applications N2-Acetyl Acyclovir Benzoate-d5 is the isotope labelled analog of N2-Acetyl Acyclovir Benzoate (A167975); a derivative of Acyclovir (A192400) which is an orally active acyclic nucleoside with inhibitory activity towards several herpes viruses. Also an antiviral.
References Collins, P., et al.: J. Antimicrob. Chemother., 5, 431 (1979); Matsumoto, H., et al.: Chem. Pharm. Bull., 36, 1153 (1988); Whitley, R.J., et al.: N. Engl. J. Med., 327, 782 (1992); Ashton, D.S., et al.: J. Chromatogr. A, 707, 367 (1995)

Applications 2-Chloro-N,N-diethylethylamine-d10 Hydrochloride is the isotope labelled analog of 2-Chloro-N,N-diethylethylamine Hydrochloride. 2-Chloro-N,N-diethylethylamine Hydrochloride used in the preparation of nonsteroidal antiestrogens. As well, it is used in the synthesis of novel cyanopyridine derivatives used in the design of antibacterial drugs.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Jones, C. et al.: J. Med. Chem., 27, 1057 (1984); Bogdanowicz, A. et al.: J. Hetero. Chem., 50, 544 (2013);

Applications Heptanoic-2,2-d2 Acid (CAS# 64118-38-3) is a useful isotopically labeled research compound.

Applications 1-Bromoundecane-d23 (CAS# 349553-92-0) is a useful isotopically labeled research compound.

Applications Irbesartan-d6 is deuterium labelled Irbesartan (I751000) which is an angiotensin II type 1 (AII1)-receptor antagonist.
References Gillis, J.C. and Markham, A.: Drugs, 54, 885 (1997); Chando, T.J., et al.: Drug. Metabol. Dispos., 26, 408 (1998),

Applications rac-Mono-(4-methyloctanyl)-phthalate-D4 is the isotopically labeled analog of rac-Mono-(4-methyloctanyl)-phthalate. rac-Mono-(4-methyloctanyl)-phthalate, is similar to di-isonoyl phthalate esters (DINPs) which are used as a major plasticizer for poly(vinyl chloride) (PVC). This family of compounds (phthalate) are considered endocrine-disrupting chemicals based on biological studies.
References Hsu, J.F., et al.: Anal. Chem., 83, 8725 (2011)

Applications 2,4-Diamino-6-hydroxypyrimidine-15N3 (cas# 1638736-04-5) is a compound useful in organic synthesis.

Applications 1,5-Diaminonaphthalene (D416415). Aromatic amines likely to have high carcinogenic potency. QSARs of aromatic amines.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Franke, R., et al.: Carcinogenesis, 22, 1561 (2001), Benigni, R., et al.: Chem. Rev., 105, 1767 (2005), Benigni, R., et al.: Environ. Mol. Mutagen., 50, 152 (2009),

Applications 1,3-Propane-d6-diamine, Dihydrochloride is used in the study of trimethylsilylated di and polyamine and their isotopically labelled analogs.
References Smith, R. G., et al.: J. Org. Chem., 43, 2178 (1978)

Applications 2-Chloroethyl (2,6-Dimethylphenyl)-carbamic Acid Ester-d6 is an intermediate used in the synthesis of Dimethachlor Ethane Sulfonic Acid Sodium Salt-d6 (D460284), which is the deuterium labelled form of Dimethachlor Ethane Sulfonic Acid Sodium Salt (D460283), which is a pesticide metabolite and pollutant found in groundwater, surface water, and wastewater.
References Huntscha, S., et al.: J. Chromatogr. A, 1268, 74 (2012); Reemtsma, T., et al.: J. Chromatogr. A, 1271, 95 (2013);

Applications N,N′-Bis(3-aminopropyl)-1,3-propanediamine-d24 is labelled N,N′-Bis(3-aminopropyl)-1,3-propanediamine which is used to prepare topoisomerase inhibitors and antitumor agents.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Gamage, S., et al.: J. Med. Chem., 44, 1407 (2001);

Applications Hexachloro-1,3-Butadiene (13c4, 99%) 100 Ug/Ml In Isooctane (cas# 93951-70-3) is a useful research chemical.

Applications An intermediate in the production of labelled Enrofloxacin.
References Chao, Q., et al.: J. Med. Chem., 52, 7808 (2009), Bebbington, D., et al.: Bioorg. Med. Chem. Lett., 19, 3586 (2009),

Applications (±)-N-(2,6-Dimethylphenyl)-1-iso-propyl-d7-2-piperidinecarboxamide (CAS# 1276197-11-5) is a useful isotopically labeled research compound.