Deuterated Compounds

<p>Applications 2-Anthraquinonesulfonic Acid Sodium Salt-d7, is the labeled analogue of Anthraquinone-2-sulfonic Acid Sodium Salt (A679280), which is used as a dopant to enhance membrane integration with electrocatalysis.<br>References Zhao,F., Liu, L., Yang, F., Ren, N.: Chem. Eng. J., 230, 491 (2013);<br></p>

<p>Applications DL-Leucine-d10 (CAS# 29909-01-1) is a useful isotopically labeled research compound.<br></p>

<p>Applications Acetamidine-d3 Hydrochloride is a useful compound in the synthesis of 3-​Chloro-​3-​methyl-​d3-​diazirine (CAS# 35496-73-2).<br>References Liu, M. T. H., et al.: J. Org. Chem., 45, 4515 (1980)<br></p>

<p>Applications A labelled methoxime derivative as internal standard for Prostaglandin assays by gas chromatography-mass spectrometry.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Herold, D.A., et al.: Prostaglandins, 33, 599 (1987),<br></p>

<p>Applications Di-n-decyl Phthalate-3,4,5,6-d4 (CAS# 1276197-18-2) is a useful isotopically labeled research compound.<br></p>

<p>Applications 3-Bromotoluene-2,4,6-d3 (CAS# 1219805-60-3) is a useful isotopically labeled research compound.<br></p>

<p>Applications Anamorelin-d6 is labelled Anamorelin (A617045) which is a novel non-peptidic ghrelin mimetic and growth hormone secratogogue.<br>References Garcia, Jose M., et al.: Growth. Horm. IGF. Res., 19(3), 267-273 (2009)<br></p>

<p>Stability Hygroscopic<br>Applications Methyl-d3 β-D-Glucuronide Sodium Salt is a compound useful in organic synthesis.<br></p>

<p>Applications Hexanedioic-d8 Acid Dihydrazide (CAS# 1202865-37-9) is a useful isotopically labeled research compound.<br></p>

<p>Applications Nexturastat A-d5 is the isotope labelled analog of Nexturastat A (N391500); a potent and selective histone deacetylase 6 (HDAC6) inhibitor that shows potential antiproliferative effects against melanoma cells.<br>References Bergman, J.A., et al.: J. Med. Chem., 55, 9891 (2012)<br></p>

<p>Applications D-Alanine-2-d1 (CAS# 56595-54-1) is a useful isotopically labeled research compound.<br></p>

<p>Applications 3-Hydroxyquinoline-d6 is labelled 3-Hydroxyquinoline (H953140) which is a chemical reagent used in the preparation cyclic peptides with an antitumor functionality. Quinoline derivative as a result of the metabolism by cytochrome P 450.<br>References Riego, E. et al.: Tetrahedron, 61, 1407 (2005); Kanou, M. et al.: Fund. Clin. Pharmacol., 16, 513 (2002)<br></p>

<p>Applications 2-Bromoacetamide-13C2 is the labelled form of 2-Bromoacetamide (B679063). 2-Bromoacetamide is a disinfectant by-product.<br>References Lv, Lu., et al.: Environ. Pollut., 205, 291-298 (2015).<br></p>

<p>Applications N-Benzoylglycine-2,2-d2 (CAS# 208928-78-3) is a useful isotopically labeled research compound.<br></p>

<p>Applications 1-Heptyne-6,6,7,7,7-d5 (CAS# 83418-35-3) is a useful isotopically labeled research compound.<br></p>

<p>Applications 1,3-Diethylbenzene-2,4,5,6-d4 (CAS# 1219803-29-8) is a useful isotopically labeled research compound.<br></p>

<p>Applications Ethyl 2,3-Dicyanopropionate-13C2 15N2, is the labeled analogue of Ethyl 2,3-Dicyanopropionate (E915950), which is an intermediate for insecticide.<br>References Cole, L., et al.: Pestic. Biochem. Physiol., 46, 47 (1993), Cole, L., et al.: Life Sci., 56, 757 (1995), Hosie, A., et al.: Br. J. Pharmacol., 115, 909 (1995),<br></p>

<p>Applications A vitamin needed to synthesize DNA, conduct DNA repair and methylate DNA, it also acts as a cofactor in biological reactions involving folate.<br>References Xu, L., et al.: Mol. Pharm., 7, 1311 (2010), Everette, J., et al.: J. Agric. Food Chem., 58, 8139 (2010), Alshatwi, A., et al.: Food, Chem., Toxicol., 48, 1881 (2010), McKay, D., et al.: Nut. J., 9 (2010),<br></p>

<p>Applications N-(Carboxymethyl)-N,N,N-trimethyl-d9-ammonium Chloride (CAS# 285979-85-3) is a useful isotopically labeled research compound.<br></p>

<p>Applications Sodium Hexadecanoate-d31 (CAS# 467235-83-2) is a useful isotopically labeled research compound.<br></p>

<p>Applications o-Xylene-alpha,alpha,alpha,alpha',alpha',alpha'-d6 (CAS# 25319-54-4) is a useful isotopically labeled research compound.<br></p>

<p>Applications 4-Bromo-2-(ethyl-d3)pyridine is an intermediate in the synthesis of Ethionamide-d3 (E890422), a labelled antibacterial (tuberculostatic) agent.<br>References Banerjee, A., et al.: Science, 263, 227 (1994), Newton, G., et al.: J. Bacteriol., 178, 1990 (1996), Baulard, A., et al.: J. Biol. Chem., 275, 28326 (2000), Koledin, T., et al.: Arch. Microbiol., 178, 331 (2002), Cardoso, R., et al.: Antimicrob. Agents Chemother., 48, 3373 (2004),<br></p>

<p>Applications Indole-2,4,5,6,7-d5-3-acetic-alpha,alpha-d2 Acid (CAS# 1173020-21-7) is a useful isotopically labeled research compound.<br></p>

<p>Applications Testosterone Hexanoate-d11 is the isotopic analog of Testosterone Hexanoate. Testosterone Hexanoate is a metabolite of testosterone(T155000), which is used in analytical studies to determine the use of anabolic steroid esters and related compounds in equine hair sample though ultra high performance liquid chromatography-tandem mass spectrometry.<br>References Gray, B.P., et al.: Analtica Chemica Acta, 787, 163 (2013); McKinney, A., et al.: Bioanalysis 1, 785 (2009)<br></p>

<p>Applications Methyl Acetate-d3 (CAS# 21300-54-9) is a useful isotopically labeled research compound.<br></p>

<p>Applications Isotope labelled 3-[2-(Ethylhexyl)oxyl]-1,2-propandiol, the novel raw material for deodorants application and is widely used as a cosmetic emollient. 3-[2-(Ethylhexyl)oxyl]-1,2-propandiol reliably inhibits the odor-causing bacteria, yeast and fungi on the skin.<br>References Nagao, S.: Frag. J., 34, 39 (2006); Lawan, K. et al.: J. Health Sci., 23, 1 (2009); Leschke, M.: SOFW J., 136, 10 (2010);<br></p>

<p>Applications 17beta-Dihydroequilin-2,4,16,16-d4 (CAS# 350819-99-7) is a useful isotopically labeled research compound.<br></p>

<p>Applications 2-Phenyl-d5-ethyl Isothiocyanate (CAS# 912627-98-6) is a useful isotopically labeled research compound.<br></p>

<p>Applications N-Suberylglycine-2,2-d2 (CAS# 1219799-02-6) is a useful isotopically labeled research compound.<br></p>

<p>Applications 2,3-Dibromo-1-propan-1,1,2,3,3-d5-ol is a labelled analogue of 2,3-Dibromo-1-propanol (D425522), which is a metabolite of the flame retardant tris(2,3-dibromopropyl) phosphate (T775560), previously shown to be a mutagen and carcinogen in experimental animals. It is also an intermediate in synthesizing Bis(2,3-dibromopropyl) Phosphate-d10 (B426237), which an isotope labelled analog of Bis(2,3-dibromopropyl) Phosphate. Bis(2,3-dibromopropyl) Phosphate is a derivative of Tris(2,3-dibromopropyl) Phosphate, a widely used flame retardant in plastic and textiles.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Pandith, A.H., et al.: Org. Chem. Int., 17, (2010); Dixon, D., et al.: Toxicol. Pathol., 36,428 (2008);Eustis, S.L., et al.: Toxiciol. Sci., 26, 41 (1994); Elliott, W.C., et al.: Life. Sci., 7, 1107 (1983);<br></p>

<p>Applications Methylcycloheptane-d3 is the isotope analog of Methylcycloheptane. It is synthesized form cycloheptanone (C989555), which is a common reagent used as the precursor for the synthesis of various pharmaceuticals including NF-κB-inducing kinase inhibitor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Li, K., et al.: Bioorg. Med. Chem. Lett., 23, 1238 (2013); Hayden, M., et al.: Cell, 132, 344 (2008); Mackay, F., et al.: Annu. Rev. Immunol., 21, 231 (2003)<br></p>

<p>Applications 2,3-Dichlorobenzoic-d3 Acid (CAS# 1126107-18-3) is a useful isotopically labeled research compound.<br></p>

<p>Applications 5-Bromo-2,4-pyrimidinedione-13C,15N2 is the isotope labelled analogue of Bromouracil, a halogenated nitrogenous base on RNA nucleosides.<br>References Morinaga, H., et al.: Bioorg. Med. Chem., 21, 466 (2013);<br></p>

<p>Applications Carcinogenic compound commonly found in hair dyes and henna ink, also a commonly used synthetic intermediate<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Mulyono; T., et al.: J. Biosci. Bioeng., 103, 147 (2007), Mosley-Foreman, C., et al.: Food Chem. Toxicol., 46, 3780 (2008), Patel, A.K., et al.: J. Agric. Food Chem., 56, 9236 (2008), Akyuz, M., et al.: J. Pharm. Biomed. Anal., 47, 68 (2008),<br></p>

<p>Applications Labelled Farnesyl Pyrophosphate. Isoprenoid from the intracellular mevalonate pathway used for prenylation of several low molecular mass G proteins, including Ras.<br>References Correll, C., et al.: J. Biol. Chem., 269, 17390 (1994), Moura, I., et al.: Antimicrob. Agents Chemother., 45, 2553 (2001), Gana-Weisz, M., et al.: Clin. Cancer Res., 8, 555 (2002),<br></p>