Organic Halides

<p>Applications 3-Chlorobenzene-1,2-diamine<br></p>

<p>Applications 2-Bromo-2-phenylacetic acid<br></p>

<p>Applications β-Chlorolactic Acid (cas# 1713-85-5) is a compound useful in organic synthesis.<br></p>

<p>Applications Pentafluorobenzoic acid (cas# 602-94-8) is a useful research chemical.<br></p>

<p>Applications Nonanoyl Chloride is used in the synthesis of immunosuppressants involving 2-aminoethanols and aminopropane-1,2-diols. Also used in the synthesis of Vanilloids with antinociceptive and antiinflammatory compounds.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kiuchi, M. et al.: J. Med. Chem., 43, 2946 (2000); Janusz, J. et al.: J. Med. Chem., 36, 2595 (1993);<br></p>

<p>Applications α,α'-Dichloro-o-xylene is a useful building block, and has been used in the preparation of nanocomposite copper metal.<br>References Nejadshafiee, V.; et al.: Turkish Journal of Chemistry, 41, 700 (2017).<br></p>

<p>Applications 1-Bromobenzene, is used as a general reagent in palladium-catalyzed reactions and in the synthesis of Grignard reagents.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Miyaura, N. et al.: Synth. Commun., 11, 513 (1981); Nahm, S. et al.: Tetra. Lett., 22, 3815 (1981);<br></p>

<p>Applications 2-Amino-4-chlorobenzenethiol is used as reagent in the synthesis of several organic compounds including that of MHY908 which is an inhibitor of melanogenesis and can potentially be used in the prevention and treatment of pigmentation disorders. Also used in the synthesis of γ-lactam analogs of prostaglandin E2 which may act as EP4 agonists.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Park, M., et al.: Arch. Pharm. Res., 38, 505 (2015); Kambe, T., et al.: Bioorgan. Med. Chem., 20, 3502 (2012);<br></p>

<p>Applications Dihexadecyl(dimethyl)azanium bromide is an ionic olefin derivative used in the preparation of metal-containing ionic liquids for use in particle synthesis and materials with magnetic or thermochromic properties.<br>References Zabel, A.; et al.: Int. J. Mol. Sci., 17, 596/1 (2016).<br></p>

<p>Applications 2-Cyclopentyl-4-chlorophenol, Technical Grade (cas# 13347-42-7) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 4-Chlorobenzenethiol is a reagent used in the synthesis of small-molecule inhibitors of the protein geranylgeranyltransferase Type I (GGTase-I), acting as anti-tumor agents. Also is used in the synthesis of β-sulfanyl carbonyl compounds via Michael addition.<br>References Ranu, B. et al.: Tetrahedron, 60, 4183 (2004); J. Med. Chem., 43, 2310 (2000);<br></p>

<p>Applications 2-(2-Aminothiazol-4-yl)acetic acid hydrochloride (cas# 66659-20-9) is a useful research chemical.<br></p>

<p>Impurity Clotrimazole EP Impurity C<br>Applications 2-Chlorotrityl Chloride (Clotrimazole EP Impurity C) is used in convergent peptide synthesis. 2-Chlorotrityl Chloride is also used in the preparation of modified trityl nucleosides as inhibitors of P. falciparum dUTPase.<br>References Ruda, G.F. et al.: ChemMedChem, 6, 309 (2011); Athanassopoulos, P. et al.: Tetrahed. Lett., 36, 5645 (1995);<br></p>

<p>Applications trans-3-(2-Chloro-3,3,3-trifluoro-1-propenyl)-2,2-dimethyl-cyclopropanecarboxylic Acid is a reagent used in the synthesis of indanyl insecticides.<br></p>

<p>Stability Moisture Sensitive<br>Applications 1-(3-Chloropropyl)theobromine (cas# 74409-52-2) is a useful research chemical.<br></p>

<p>Applications 1,2,4-Trichlorobenzene is a solvent in various organic chemical reactions.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Legrand, Y. et al.: J. Am. Chem. Soc., 125, 15789 (2003); Aver'yanov, V. et al.: Kin. Cata., 43,175 (2002);<br></p>

<p>Applications A metabolite of Bis(2-chloroethyl) Ether.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lingg, R.D. et al., Arch. Environ. Con. Tox., 11, 173 (1982)<br></p>

<p>Impurity Azelastine EP Impurity E /Azelastine USP RC E<br>Applications Stilbene-related benzalphthalide derivative with with potential anti-HIV and leishmanicidal activity. It has anxiolytic effects and maybe useful in the development of a non-benzodiazepinic and non-nitrogenated antianxiety agents.An impurity arising in the synthesis of azelastine (A808250).<br>References Zamilpa, A. et al.: Bioorg. Med. Chem. Lett., 15, 3483 (2005); Bedoya, L.M. et al.: Bioorg. Med. Chem. Lett., 16, 4075 (2006); del Olmo, E. et al.: Bioorg. Med. Chem. Lett., 11, 2123 (2001);<br></p>

<p>Applications 5-Bromo-1,2,3-trichlorobenzene is a useful intermediate in the preparation of isoxazole derivatives for controlling parasites, such as Rhipicephalus sanguineous nymphs.<br>References Gauvry, Noelle., et al.: PCT Int. Appl., WO 2012120135 A1 20120913. (2012);<br></p>

<p>Applications 4,4,5,5,6,6,7,7,7-nonafluoroheptan-1-ol (cas# 83310-97-8) is a useful research chemical.<br></p>

<p>Applications 1,8-Dichloroanthraquinone is a reagent in the preparation of anthraquinones, which has antitumor activities.<br>References Barasch, D., et al.: Eur. J. Med. Chem., 34, 597 (1999)<br></p>

<p>Applications Di-β,β'-Chloroethylphosphoric Acid, is a dialkyl hydrogen phosphates, that can undergo the electrophilic trifluor- omethylation to produce trifluoromethyl phosphates in order to increase the lipophilicity of functional groups.<br>References Santschi, N., et al.: J. Fluorine Chem., 135, 83 (2012);<br></p>

<p>Applications 2,2-Dichloro-1-(2,4-dichlorophenyl)ethanone is used in the synthesis of acid chloride phenylhydrazones in a broad-spectrum anthelmintic series.<br>References Rector, D. et al.: J. Med. Chem., 24, 532 (1981);<br></p>

<p>Applications Dibromoacetamide is a byproduct produced from water purifciation processes.<br>References Chuang, Y., et al.: Env. Sci. Tech., 53, 3729 (2019);<br></p>

<p>Stability Light Sensitive, Volatile<br>Applications Trichloroacetonitrile is a by-product of the chlorine disinfection of water and is commonly used as a fumigant. It is also used as a direct alkylating agent and reacts with primary and secondary aliphatic amines to produce N-substituted trichloroacetamidines.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Christ, S.: J. Toxicol. Env. Health A, 47, 233 (1996); Davies, M. &amp; Jenkin, D.: J. Chem. Soc., No vol. given, 2374 (1954); Grivas, J. &amp; Taurins, A.: J. Chem., 36, 771 (1958)<br></p>

<p>Applications A chemical additive to control bacterial contamination in ethanol fermentation.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Vaisanen, O., et al.: J. Ind. Microbio., 4, 419 (1989), Costerton, J., et al.: J. Bacteriol., 176, 2137 (1994), Pirttijarvi, T., et al.: J. Appl. Bacteriol., 81, 445 (1996),<br></p>

<p>Applications 2-Chloro-1-(3,4-dihydroxyphenyl)ethanone (cas# 99-40-1) is a compound useful in organic synthesis.<br></p>

<p>Stability Hygroscopic<br>Applications Used in nucleophilic substitution.<br>References Genicot, C., et al.: Bioorg. Med. Chem. Lett., 13, 437 (2003),<br></p>

<p>Stability Hygroscopic<br>Applications 3-[[[2-[(Diaminomethylene)amino]-4-thiazolyl]methyl]thio]propanimidamide hydrochloride (cas# 76833-47-1) is a useful research chemical.<br></p>

<p>Applications 2,4,6-Tribromophenyl Acetate (cas# 607-95-4) is a compound useful in organic synthesis.<br></p>

<p>Applications Shows some anti-viral activity due to the adamantane structure. In addition it shows anti-microbial activity and cytotoxic application.<br>References Aigami, K. et al.: J. Med. Chem., 18, 713 (1975); Aigami, K. et al.: J. Pharm. Res., 4, 1407 (2011);<br></p>

<p>Applications 10-Bromo-1-aminodecane, Hydrobromide (cas# 24566-82-3) is a compound useful in organic synthesis.<br></p>

<p>Applications 6,8-Dichloro-octanoate is an Intermediate in the synthesis of α-Lipoic acid (L468750) and its derivatives.<br>References Zhang, S.J. et al: Bioorg. Medn. Chem. Letters., 20, 3078 (2010);<br></p>

<p>Applications Diethylamine Hydrochloride is a secondary amine and a precursor of Atrazine (A794600). It is used as a reactant if the production of pesticides, dyes and pharmaceutical compounds.<br>References Raghuram, P. et al.: Chromatograph., 71, 963 (2010); Smith, D. &amp; Crowley, D.: FEMS Microbiol. Ecol., 58, 271 (2006); Asiri, A.: Dyes and Pigments., 42, 209 (1999); Rijhsinghani, K. et al.: Canc. Det. Prev., 5, 283 (1982)<br></p>

<p>Applications 4,6-Dichloronicotinic acid<br></p>

<p>Applications p-Toluidine Trifluoroacetamide (cas# 350-96-9) is a compound useful in organic synthesis.<br></p>

<p>Applications 5-Chloronicotinic Acid is used as reagent/reactant luminescence and hydrothermal preparation of cobalt/cadmium/lead chloronicotinate phenanthroline MOF.<br>References Gao, Z.Q., et al.: J. Solid State Chem., 241, 121-130 (2016)<br></p>

<p>Applications Di-tert-butyldichlorosilane (cas# 18395-90-9) is a useful research chemical.<br></p>

<p>Applications Methyl 2-Bromomethylbenzoate is a reactant in the preparation of Methyl 2-((4-(2-(2-methylphenoxy)acetyl)piperazin-1-yl)methyl)benzoate with neuroprotective activity.<br>References Zhong, Y., et. al.: Chin. J. Struct. Chem., 33, 1096 (2014)<br></p>

<p>Applications 4-[(2-chloroacetyl)amino]benzoic acid (cas# 4596-39-8) is a useful research chemical.<br></p>

<p>Applications Ethylamine Hydrochloride a chemical used in various chemical organic syntheses and biological studies.<br>References Miller, M.M. et al.: Bioorg. Med. Chem. Lett., 22, 6503 (2012); Yasui, K. et al.: Prot. Sci., 19, 486 (2010);<br></p>

<p>Applications Octafluorocyclopentene (cas# 559-40-0) is a useful research chemical.<br></p>

<p>Applications DIISOPROPYLAMINE HYDROCHLORIDE (cas# 819-79-4) is a useful research chemical.<br></p>

<p>Applications 11-Bromoundecanenitrile is an intermediate in synthesizing N-(12-Aminododecyl)deoxynojirimycin (A608080), which is used in the preparation of imino-alditols as glycosidase inhibitors.<br>References Jefferies, I., et al.: Bioorg. Med. Chem. Lett., 7, 1171 (1997); Hassan, A., et al.: Carbohydr. Res., 339, 1565 (2004); Lundt, et al.: Bioorg. Med. Chem., 14, 1737 (2006);<br></p>

<p>Applications 2-bromo-6-chlorophenol (cas# 2040-88-2) is a useful research chemical.<br></p>

<p>Applications Methoxylamine is a methoxime derivative used as internal standard for Prostaglandin assays by gas chromatography-mass spectrometry.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Herold, D.A. et al.: Prostaglandins, 33, 599 (1987);<br></p>