Organic Halides

Applications An intermediate in the preparation of Ondansetron impurities and organic polymers.

Applications 2-[(5-Bromo-2-fluorophenyl)amino]propanamide (cas# 1218082-92-8) is a compound useful in organic synthesis.

Applications 1,1-(Ethylenedioxy)-3-bromopropane is used in the synthesis of EGFR inhibitors. Also used in the synthesis of orally active agents of cancer and cell proliferation with quinoline substructures.
References Zhang, X. et al.: Arch. Pharm., 346, 44 (2013); Lee, Y. et al.: J. Med. Chem., 55, 10363 (2012);

Applications 3-(Aminomethyl)-4-fluorophenol Hydrobromide is derived from 2-Fluoro-5-methoxybenzaldehyde, which is versatile reactant used in the solid-phase synthesis of BODIPY dyes and development of an immunoglobulin fluorescent sensor.
References Vendrell, M., et al.: Chem. Commun., 47, 8424 (2011);

Applications 2-Fluoroethyl Tosylate is an intermediate used in the preparation and pre-clinical evaluation of new class of high-affinity 18F-labeled PSMA ligands for detection of prostate cancer by positron emission tomography (PET) imaging.
References Kelly, J., et al.: Eur. J. Nucl. Med. Mol. Imaging, 44, 647 (2017)

Applications 4-Fluorobenzophenone is a Wittig reagent.
References Buschauer, A., J. Med. Chem., 32, 1963 (1989); Yamataka, H., et al.: J. Org. Chem., 53, 3877 (1988)

Applications (S)-4-Chlorostyrene oxide is used in the biosynthetic preparation though epoxidation of styrene and substituted styrenes by whole cells of Mycobacterium.
References Rigby, S. R., et al.: Bioorg. Med. Chem. 2, 553 (1994);

Applications 1-Bromo-3-iodobenzene is a useful compound for preparing an organic light-emitting device.
References Park, S. U., et al.: Repub. Korea (2020), KR 2176164 B1

Applications 3-Bromo-5-chlorotoluene is a reagent used in the synthesis of novel benzophenones towards the discovery of potent, next generation HIV nonnucleoside reverse transcriptase inhibitors.
References Romines, K. et al.: J. Med. Chem., 49, 727 (2006); Chan, J. et al.: J. med. Chem., 44, 1866 (2001);

Applications 1-(2,3-dichlorophenyl)ethanone (cas# 56041-57-7) is a useful research chemical.

Stability Moisture Sensitive
Applications Trifluoromethanesulfonic Anhydride is a strong electrophile used in chemical synthesis for introducing the triflyl group.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Cai, D. et al.: Org. Synth., 10, 112 (2004);

Applications Tryptamine hydrochloride (cas# 343-94-2) is a useful research chemical.

Applications 5H-Octafluoropentanal (cas# 2648-47-7) is a useful research chemical.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications O-TOLIDINE DIHYDROCHLORIDE (cas# 612-82-8) is a useful research chemical.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications Methyl adipoyl chloride is a reagent that is used for improved heme-mimetics based on BAY 58-2667 (cinaciguat) and their effects on soluble guanylyl cyclase (sGC) activity.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References von Wantoch Rekowski, M., et al.: J. Med. Chem., 56, 8948 (2013);

Applications Trimethyl-tetradecylammonium chloride,99% (cas# 4574-04-3) is a useful research chemical.

Applications 5-[1-Hydroxy-2-(2,4,5-trifluorophenyl)ethylidene]-2,2-dimethyl-1,3-dioxane-4,6-dione is an impurity of the DPP-IV inhibitor Sitagliptin (S491000).
References Ye, F. et al.: Hech. Huax., 18, 767 (2010); Ahn, J.H, et al.: Bioorg. Med. Chem. Lett., 17, 2622 (2007);

Applications tert-Butyl Bromoacetate is a halogenated t-butyl acetate commonly used as an alkylating agent. tert-Butyl Bromoacetate is used in the synthesis of collagenase inhibitors.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Steinman, D.H. et al.: Bioorg. Med. Chem. Lett., 8, 2087 (1998); Fray, M.J. et al.: J. Med. Chem., 46, 3514 (2003): Neri, P. et al.: J. Org. Chem., 59, 3880 (1994);

Applications 2-Bromo-4-aminobenzoic Acid (cas# 2486-52-4) is a compound useful in organic synthesis.

Applications 4-(4-Fluorophenyl)aniline

Applications 4-{[(p-Fluorophenyl)imino]methyl}phenol is used in the preparation of benzylacetones which promote anti-fungal activity.
References Sandhar, R. et al.: J. Ind. Council Chem., 22, 32 (2005);

Applications 2-(4-Octylphenyl)-1-iodoethane (cas# 162358-07-8) is a compound useful in organic synthesis.

Applications 3-amino-5-chloro-1,3-dihydro-2H-indol-2-one hydrochloride (cas# 1104895-64-8) is a useful research chemical.

Applications 4-Nitrobenzoyl Chloride is used inorganic syntheses such as Michael additions. Also used in the synthesis of polysubstituted furanonaphthoquinoines.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Zhong, J. et al.: Catal. Comm., 32, 18 (2013); Wu, Z. et al.: Org. Biomol. Chem., 11, 828 (2013);

Applications 1-Bromo-3-phenylpropane is used in the synthesis of MraY natural inhibitors as antibacterial agents. Also used in the preparation of quinolinone derivatives as potent and selective MAO-B inhibitors.
References Fer, M. et al.: J. Org. Chem., 78, 10088 (2013); Meiring, L. et al.: Bioorg. Med. Chem. Lett., 23, 5498 (2013);

Applications Reagent used in the preparation of cyclopropane derivatives.
References Antipenko, L., et al.: Chem. Pharm. Bull., 57, 580 (2009), Kumar, A., et al.: Bioorg. Med. Chem., 17, 5285 (2009),

Applications 4-Bromo-3-hydroxyphenylboronic Acid (cas# 1701448-16-9) is a useful research chemical.

Applications 4,4'-Dichlorodiphenyl Ether is a standard for environmental testing and research. Substance for the QSPR/QSAR models for prediction of physico-chemical properties and biological activity of polychlorinated diphenyl ethers.
References Xu, H., et al.: Chemosphere, 80, 665 (2010)

Applications (Chloromethyl)cyclopropane is a used as a reagent to synthesize 6-alkylamino-9-alkylpurines, compounds that have potential to be antipsychotic agents. (Chloromethyl)cyclopropane is also used as a reagent to prepare acylmorphinans, a class of compounds that have analgesic effects in rats.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Kelley, J., et al.: J. Med. Chem., 40, 3207 (1997); Mohacsi, E., et al.: J. Med. Chem., 28, 1177 (1985)

Applications 1-Bromo-4-ethylbenzene is organo bromide with flame retardant properties.
References Day, M. et al.: J. Fire Sci., 1, 255 (1983);

Applications N-(4-Chlorophenyl)-2,6-Difluorobenzamide (cas# 122987-01-3) is a useful research chemical.

Applications 4-bromo-2-ethyl-1-fluorobenzene (cas# 627463-25-6) is a useful research chemical.