Organic Halides

<p>1-(5-Chloro-2-hydoxyphenyl)ethanone is a potent inhibitor of the antiapoptotic protein survivin. It binds to the carbonyl group of the molecule, which is located on the intramolecular hydrogen bond surface. This leads to conformational changes in the molecule and ternary complex formation, which eventually leads to apoptosis protein aggregation and activation. 1-(5-Chloro-2-hydoxyphenyl)ethanone has been shown to inhibit prostate cancer cells and has also been studied in clinical trials for its anticancer properties.</p>

<p>Please enquire for more information about H-Gly-p-iodo-Phe-Trp-OH trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>L-Phenylalanine benzyl ester hydrochloride is an ester of L-phenylalanine and benzoic acid. It has a solubility of 1.9g/L in water, 2.1g/L in methanol, and 0.8g/L in acetonitrile at 20°C. The melting point is 119°C to 120°C and the boiling point is 243°C to 244°C at atmospheric pressure. This compound can be synthesized by reacting formamide with L-phenylalanine chloride in the presence of hexamethylphosphoramide as a catalyst.</p>

<p>Please enquire for more information about Human CMV pp65 (495-503) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Sauvagine is a trifluoroacetate salt of Pyr-Gly-Pro-Pro-Ile-Ser-Ile-Asp-Leu-Ser-Leu-Glu-Leu-Leu-Arg. It has been used as a model system to study the effects of trifluoroacetic acid on brain functions. Sauvagine has also been shown to have inhibitory effects on cyclase enzymes, which are involved in the synthesis of steroids and other hormones. This compound has also been found to have an effect on locomotor activity and receptor activity.</p>

<p>Please enquire for more information about C-Peptide 1 (rat) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Lys-Lys-IRS-1 (891-902) (dephosphorylated) (human) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about (Tyr1)-TRAP-7 trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Ac-Cys(dodecyl)-chloromethylketone including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Amyloid beta-Protein (1-24) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Methyl 3,5-dichloro-4-methoxybenzoate is a fine chemical and useful building block for research chemicals. It belongs to the class of speciality chemicals and can be used as a reagent in organic synthesis. Methyl 3,5-dichloro-4-methoxybenzoate is a versatile building block that has been reported in the synthesis of many complex compounds. This compound can also be used as an intermediate or scaffold for medicinal chemistry applications.</p>

<p>Please enquire for more information about Cell-permeable Caspase-1 Inhibitor I trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>5-Chloro-2,4-dimethoxyaniline (5-CDA) is a crystalline solid that belongs to the amine class of chemical compounds. It is used in the production of polyhalogenated anilines and nitrosamines, which are known carcinogens. 5-CDA has been shown to be toxic to animals at high doses and can cause health effects such as irritation of the eyes, skin, and respiratory tract; central nervous system depression; and gastrointestinal disturbances. The toxicity of this compound is related to its ability to form nitrosamines when it comes into contact with nitrite or other N-nitroso compounds. 5-CDA is also present in wastewater effluents from paper mills and agricultural runoff from triticum aestivum fields.</p>

<p>Please enquire for more information about Hippuryl-Cys(2-aminoethyl)-OH hydrochloride salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>3-Fluoroamphetamine hydrochloride (3FAH) is a histological and microscopic technique used to study the effects of analgesics on human skin. 3FAH is an analgesic that has been shown to reduce pain in a number of studies. It has also been observed to enhance the effects of laser treatments on human skin, as it reduces inflammation and increases transdermal permeation. This drug is applied topically or injected for the treatment of pain, muscle spasms, or Parkinson’s disease. 3FAH can be administered by iontophoresis or permeation techniques, which are both effective ways to deliver drugs through skin.</p>

<p>1,3-Difluoro-2-vinylbenzene is a hydroborating reagent that can be used to make alcohols from alkyl halides. It is also a potential sensor for the environment and has linearity in its response. 1,3-Difluoro-2-vinylbenzene may be an alternative to traditional hydroborating agents, such as diborane, which are toxic and expensive. This compound is sensitive to moisture and should be stored under nitrogen or argon gas.</p>

<p>Please enquire for more information about Neuropeptide Y (free acid) (human, rat) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Neuronostatin-19 (mouse, rat) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Gabapentin is a pharmaceutical preparation that is used for the treatment of epilepsy and neuropathic pain. It is also used for postherpetic neuralgia, bipolar disorder, and anxiety disorders. Gabapentin has been shown to bind reversibly to the enzyme adenylate cyclase, which regulates the production of the second messenger cAMP. The binding of gabapentin to this enzyme prevents the conversion of ATP into cAMP and blocks signal transduction. This leads to an increase in intracellular levels of adenine nucleotides (ATP) and suppression of neuronal activity. Gabapentin has high values in kinetic tests because it is a reversible inhibitor with a low Km value. It binds irreversibly to nucleophilic substitutions, which are enzymes that catalyze reactions involving hydrolysis or transfer of one or more hydrogen ions from one molecule to another in a chemical reaction. A fluorine atom on gabapentin's structure may account for its</p>

<p>Please enquire for more information about (Des-Gly10,D-Leu6,[13C6]Leu7,Pro-NHEt 9)-LHRH trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Pancreatic Polypeptide (1-17)-(Ala31, Aib 32)-Neuropeptide Y (18-36) (human) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about cis-Octahydro-cyclopenta[C]pyrrole hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Neuropeptide Y (human, rat) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Fluorescein-6-carbonyl-Ile-Glu(OMe)-Thr-DL-Asp(OMe)-fluoromethylketone including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Gly-Pen-Gly-Arg-Gly-Asp-Ser-Pro-Cys (GPEG) is a peptide that modulates the function of muscle cells and is present in collagen. GPEG has been shown to improve oxidative damage, which occurs during exercise. The effect of GPEG on muscle cells is dependent on the dose. Low doses of GPEG activate proteins that are involved in transcription and increases the synthesis of oxidative enzymes, while high doses inhibit these proteins. GPEG also modulates integrin receptor expression and decreases fibronectin production by vascular smooth muscle cells.</p>

<p>Amyloid beta-protein (Aβ) is a peptide that is associated with the development of Alzheimer's disease. The Aβ(16-20) trifluoroacetate salt (ATF) has been used in the diagnosis of Alzheimer's disease by fluorescence microscopy. This compound binds to hyaluronic acid and has been used as a coating for optical fibers and other materials, such as coatings for mitochondria for use in live cell imaging. The ATF also interacts with mitochondria and alters mitochondrial membrane potential, which may be due to its ability to displace cardiolipin from the inner mitochondrial membrane. ATF binds to unsymmetrical dimethylarginine (DMA), an endogenous nitric oxide synthase inhibitor, and selectively inhibits only cancer cells that have elevated levels of DMA. ATFP also induces spontaneous apoptosis in human carcinoma cells when bound to these cells via a photoconjugation reaction with bioconjugate chemistry.</p>

<p>5-Bromoisatoic anhydride is an antibiotic that inhibits the enzyme ido1, which is involved in the synthesis of amines. This chemical has been shown to have inhibitory activity against cancer cells and potential antitumor properties. 5-Bromoisatoic anhydride has also been shown to have antimicrobial properties. It binds to bacterial ribosomes, inhibiting protein synthesis and leading to cell death by inhibiting the production of proteins vital for cell division. 5-Bromoisatoic anhydride has been shown to be active against staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa isolates. The compound also shows inhibitory activities against Flavus assays and human colon carcinoma HCT116 cells.</p>

<p>Please enquire for more information about Fibronectin Fragment (1954-1959) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Intermedin (rat) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>4-Chlorophenylboronic acid is a chemical compound that is used in the industrial preparation of biphenyl. It is produced by the Friedel-Crafts reaction between chlorine and 4-methoxyphenylboronic acid. This reaction can be carried out using a variety of solvents, such as chloroform or carbon tetrachloride. The optimal reaction conditions are acidic pH values, which are achieved by adding sodium carbonate to the solution. The product can be purified by distillation or crystallization. 4-Chlorophenylboronic acid can also be used for the synthesis of organic compounds through cross-coupling reactions with organometallic reagents, such as palladium chloride and triphenylphosphine, or through asymmetric synthesis with chiral ligands like (S)-proline and 2-(diphenylphosphino)ferrocene.</p>

<p>Please enquire for more information about (His(1-Me)2)-LHRH trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Peptide YY (13-36) (canine, mouse, porcine, rat) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Boc-(±)-trans-4-(3-trifluoromethylphenyl)pyrrolidine-3-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about (Des-Gly10,D-Pyr 1,D-Leu6,Pro-NHEt 9)-LHRH trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>The monoclonal antibody (mAb) is a recombinant protein that binds to the extracellular region of the vasopressin receptor. It is used in pharmacological research to study the physiological function and pharmacological effects of vasopressin. The mAb has been shown to be minimally toxic, with an LD50 value of greater than 10 mg/kg in mice. It has also been shown to inhibit viruses and inhibit drug-sensitive enzymes. This antibody can be used as a diagnostic tool for congestive heart disease, as well as in experimental models for studying the minimal toxicity and tumor treatment properties of various drugs.</p>

<p>5-Bromo-2-fluorophenol is an organic solvent that is used in hydrotalcite to extract biphenyl. 5-Bromo-2-fluorophenol has been shown to have a high affinity for the cavity of hydrotalcite, which is a desorption technique. It can also be used to extract supramolecular systems and biomolecules, such as proteins and nucleic acids. The nature of 5-bromo-2-fluorophenol is an aromatic compound with a density of 1.40 g/mL at 20°C and a boiling point of 221°C. 5-Bromo-2-fluorophenol can be eluted using isopropyl alcohol or ethyl acetate, and the transfer rate depends on the nature of the solvent used in elution.</p>

<p>9-Fluorenone hydrazone is a compound that belongs to the group of chemical compounds known as heterocycles. It can be synthesized by reacting 9-fluorenone with hydrazine. The synthesis proceeds via an intramolecular hydrogen transfer reaction, which forms an unsymmetrical aldehyde. This aldehyde is oxidized to form the corresponding hydrazone through protonation and subsequent attack of a nitrogen nucleophile. Hydrazones are important for their antimicrobial properties and are used in the treatment of bacterial infections such as tuberculosis and leprosy. They are also used in the production of dyes and pharmaceuticals. The mechanism for this reaction involves the formation of an intermediate carbocation, followed by deprotonation to form the final product.</p>

<p>3-Chloro-2-nitrobenzyl alcohol is a chemical compound that has a molecular formula of C6H5ClNO2. This substance was synthesized by the reaction of 3-chloro-2-nitrobenzyl chloride with sodium hydroxide in methanol. The optimized geometry and vibrational frequencies were calculated using density functional theory (DFT) and theory of Raman scattering. The IR spectra were measured with Fourier transform infrared (FTIR) spectroscopy, which showed that the compound has a strong absorption in the region from 2,600 to 2,800 cm−1.</p>

<p>Please enquire for more information about Mca-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(Dnp)-NH2 trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Nociceptin trifluoroacetate salt is an opioid with low potency that is used in the treatment of pain. It has been shown to bind to the protein and inhibit protease, which has been proposed as a possible mechanism for its analgesic effects. Nociceptin trifluoroacetate salt may also have indirect effects on brain functions by regulating levels of nociceptin, a neuropeptide that interacts with nociceptive neurons in the brain. This drug has been shown to have nootropic effects in mice, including increased locomotor activity and improved memory retention. Nociceptin trifluoroacetate salt inhibits kappa-opioid receptors and is therefore used as a pharmacological tool for research into opioid receptor function.</p>

<p>Please enquire for more information about 4-Nitro-D-phenylalanine methyl ester hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>3,4-Dichlorothiophenol is a chemical compound that belongs to the group of reactive compounds. It can be used as a chemical intermediate for the synthesis of other organic compounds. 3,4-Dichlorothiophenol is an inhibitor of methylating enzymes such as glyoxalase I and II and glyceraldehyde-3-phosphate dehydrogenase. This inhibition leads to the accumulation of methylglyoxal and 3-deoxyglucosone in cells, which are potent inhibitors of protein glycosylation. 3,4-Dichlorothiophenol also inhibits nucleophilic attack on DNA by epoxide hydrolases such as epoxide hydrolase 1 and 2. This inhibition results in the accumulation of reactive metabolites that are covalently adducted with DNA bases.</p>

<p>Fibronectin CS-1 Fragment (1978-1985) trifluoroacetate salt H-Glu-Ile-Leu-Asp-Val-Pro-Ser-Thr-OH trifluoroacetate salt is a peptidomimetic with peroxidase activity. It has the ability to bind to red blood cells and monoclonal antibodies, which are used in spatially specific immunoassays. Fibronectin CS-1 Fragment (1978-1985) trifluoroacetate salt H-Glu-Ile-Leu-Asp-Val-Pro-Ser-Thr-OH trifluoroacetate salt also has an effect on hyperresponsiveness and can be used as a costimulatory antigen for cancer immunotherapy.</p>

<p>Histidine is a non-essential amino acid that has been shown to be involved in the regulation of cell growth and differentiation. It is also involved in the biosynthesis of nucleotides, collagen, and carnitine. Kinetic studies on histidine have been done by acetylation of histidine with acetic anhydride and pyridine. The kinetic method used was based on the reaction between histidine and p-nitrophenyl phosphate. The transfer reactions were performed with a strain containing lysine residues which were then adsorbed onto a surface-enhanced Raman spectroscopy (SERS) substrate. These experiments were performed using techniques such as resonance mass spectrometry (RMS), surface-enhanced Raman spectroscopy (SERS), and protonation selective mass spectrometry (PSMS).</p>

<p>N-alpha-Z-L-lysine methyl ester hydrochloride is a preparation that is used as a methyl ester. It is an ester of lysine and methyl chloride. This product has a molecular weight of 170.16 g/mol and the chemical formula CH3CONHCH2CH(NH)CO2CH3. The structural data has not been confirmed by X-ray crystallography, but it can be assumed to be in the form of a zwitterion. N-alpha-Z-L-lysine methyl ester hydrochloride can be used for the synthesis of peptides, which are building blocks for proteins and enzymes. N-alpha-Z-L-lysine methyl ester hydrochloride is also used in the production of certain kinds of drugs and organic acids such as acetylsalicylic acid (aspirin).</p>

<p>Please enquire for more information about Ac-Val-Met-[(2S,4S,5S)-5-amino-4-hydroxy-2-isopropyl-7-methyl-octanoyl]-Ala-Glu-Phe-OH trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Angiotensin A trifluoroacetate salt H-Ala-Arg-Val-Tyr-Ile-His-Pro-Phe-OH is a drug that has been shown to be effective in treating chronic kidney disease and heart failure. It is a synthetic peptide that mimics the activity of angiotensin II, an important regulator of blood pressure. Angiotensin A trifluoroacetate salt H-Ala-Arg-Val-Tyr-Ile-His-Pro-Phe-OH binds to the angiotensin receptor, which causes vasoconstriction and increases the release of soluble guanylate cyclase. This drug also inhibits the production of matrix metalloproteinases, which break down collagen and other extracellular proteins.</p>

<p>Please enquire for more information about Fluorescein-6-carbonyl-Val-Glu(OMe)-Ile-DL-Asp(OMe)-fluoromethylketone including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>A component of Conus venom; antagonist of nicotinic acetylcholine receptors</p>

<p>Please enquire for more information about (Asp28)-Exenatide trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>