Organic Halides

<p>2-Bromo-3-fluoroaniline is a reactive and nucleophilic compound that is synthesized by the reaction of aniline with bromine and sodium hydroxide. The drug development of 2-bromo-3-fluoroaniline has been hampered by its toxicity, but it has shown promising results in animal studies for the treatment of cancer. Mechanistic studies have demonstrated that 2-bromo-3-fluoroaniline causes cell death by reacting with DNA. This drug also acts as a prodrug to fluoroacetic acid, which inhibits cell proliferation by inhibiting protein synthesis.</p>

<p>Z-Ala-Pro-Phe-chloromethylketone is a cytosolic protein that performs its function by denaturing proteins and is localized in the cytosol. It has been shown to be active against a number of bacteria, including Bacillus licheniformis and Listeria monocytogenes, as well as some fungi. Z-Ala-Pro-Phe-chloromethylketone targets the membrane potential in mitochondria and chloromethyl ketone is a strategy for inhibiting membrane potential in mitochondria. The x-ray diffraction data show that this protein forms a molecule with an alpha helix structure. It binds to the mitochondrial inner membrane by ligation and inhibits mitochondrial membrane potential.</p>

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<p>3,3'-Diiodo-L-thyronine (T2) is a thyroid hormone that binds to the DNA response element in the promoter region of its target genes. It has been shown to decrease the transcription of genes encoding for proteins involved in energy metabolism and thus may play a role in weight loss. T2 also inhibits the production of hydrochloric acid by human gastric cells, which may lead to a reduction of stomach acidity. T2 is detectable in serum within 3 hours following ingestion and can be quantified using high performance liquid chromatography with electrochemical detection. The matrix effect is a phenomenon that occurs when samples are analyzed using different analytical methods and this must be taken into account when interpreting results. T2 has been shown to have pharmacological effects on experimental animals, including the stimulation of liver cell growth and an increase in metabolic rate.</p>

<p>(R)-3-Amino-4-(2,4,5-trifluorophenyl)butyric acid is an antibacterial agent that inhibits the enzyme acetylcholine esterase. This inhibition prevents the breakdown of acetylcholine, leading to increased levels of this neurotransmitter in the brain and an enhancement of cholinergic transmission. (R)-3-Amino-4-(2,4,5-trifluorophenyl)butyric acid has been shown to be effective against bacterial strains resistant to β-lactam antibiotics. The synthesis of taxol as well as other β-amino acids has been demonstrated using a variety of enzymatic methods. A reaction scheme for the synthesis of nicotinic acetylcholine has also been proposed. (R)-3-Amino-4-(2,4,5-trifluorophenyl)butyric acid is a dipept</p>

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<p>3-Methoxybenzyl chloride is a polymer conjugate that has the chemical formula C6H5CH2ClO. It reacts with hydroxy groups to form ester bonds. The compound was synthesized by reacting 3-methoxybenzyl chloride with hydrochloric acid in vitro, and the resulting product was found to have antimicrobial properties. In vivo studies have shown that this compound binds to receptors in rat striatal tissue. 3-Methoxybenzyl chloride also showed fluorescence properties when exposed to ultraviolet light and can be used for molecular modeling. Titration calorimetry has been used to study the thermal stability of this polymer conjugate.</p>

<p>2-Chloro-N-[2-(diethylamino)ethyl]-4-quinolinecarboxamide is a carboxamide analog of dibucaine. It is synthesized from chloroacetyl chloride and isatin in the presence of sodium hydroxide. The synthesis has been scaled to an industrial level. 2-Chloro-N-[2-(diethylamino)ethyl]-4-quinolinecarboxamide has been shown to have analgesic properties, similar to those of dibucaine. Radiolysis of this compound gives a carboxylic acid and a heterocyclic ring product.</p>

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<p>Please enquire for more information about Monocyte Chemotactic Protein-1 (65-76) (human) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Dnp-(Leu421)-Collagen Type VIII a1 Chain (419-426) amide (human, mouse) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

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<p>2,3,5-Trichlorobenzaldehyde is a chemical compound that has been shown to have anticancer and apoptotic effects. It inhibits the growth of bacteria by chelating iron ions and inhibiting bacterial dna synthesis. 2,3,5-Trichlorobenzaldehyde has also been shown to inhibit the growth of cancer cells in culture in an experimental study. This chemical has been used as a substrate for nmr spectroscopy to study its functional groups and radical scavenging activities. 2,3,5-Trichlorobenzaldehyde can be synthesized from phenacyl chloride and benzaldehyde in the presence of hydrogen chloride gas. The carbonyl group in 2,3,5-trichlorobenzaldehyde may cause metabolic disorders such as diabetes mellitus or hyperglycemia.</p>

<p>Indium (III) chloride is a reactive metal with a high oxidation state that has been shown to have significant cytotoxic effects in vitro. It is also genotoxic, which may be due to the generation of hydroxyl radicals and other reactive oxygen species. Indium (III) chloride has been used for the treatment of various infectious diseases, including HIV, Epstein-Barr virus, herpes simplex virus type 1, and influenza A virus. The toxicity of this metal is dependent on the concentration and duration of exposure. Indium (III) chloride is metabolized by plasma mass spectrometry as a substrate molecule for cytochrome P450 enzymes. This reaction results in the formation of an active metabolite that can bind to DNA and affect mitochondrial membrane potential. Indium (III) chloride has also been used as a contrast agent in fluorescein angiography or particle imaging techniques to visualize the presence of biological materials such as tissue necrosis or inflammation.</p>

<p>3,6-Dichloro trimellitic anhydride is a reactive compound that is used in the synthesis of fluorescent probes. It is also used as a reagent to introduce chlorine substituents onto organic molecules. Fluorescence measurements can be used to determine the purity of 3,6-dichloro trimellitic anhydride. This compound reacts with nucleic acids, causing them to fluoresce and making them detectable by spectroscopy. 3,6-Dichloro trimellitic anhydride has been used in research involving the study of nucleic acids and their role in DNA replication and repair.</p>

<p>Phenyl-magnesium bromide solution is a chemical compound that can be used as a pesticide. It has been shown to have carcinoid syndrome-inducing properties in animal studies. Phenyl-magnesium bromide solution has also been found to have biological properties that are beneficial for bowel disease, organometallic reactivity, and congestive heart failure. This chemical compound reacts with ester hydrochloride in the presence of an organic base to form a reactive intermediate that undergoes transfer reactions with other organic compounds. Phenyl-magnesium bromide solution is reactive and can cause metabolic disorders such as palladium-catalyzed coupling.</p>

<p>Endogenous heptapetide which causes vasodilation and has anti-hypertensive properties.</p>

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<p>Chloromethyl isopropyl carbonate (CIC) is a prodrug that is converted to disoproxil in the body. It has significant cytotoxicity and antiviral activity against HIV and other viruses, but has not been used clinically due to its chemical instability. CIC can be administered orally as a prodrug, with the active form of CIC being tenofovir disoproxil. Tenofovir disoproxil is metabolized by proximal tubules and has shown efficacy for treating hepatitis B and C. Tenofovir has also been shown to decrease the incidence of renal disease in HIV patients.</p>

<p>2-(2-Bromoethoxy)tetrahydro-2H-pyran is a synthetic molecule that has been shown to act as an estrogen receptor modulator, which has the potential to be used for the treatment of hormone-sensitive diseases such as breast cancer. This compound is chemically very similar to other compounds that have been shown to be effective in treating breast cancer. 2-(2-Bromoethoxy)tetrahydro-2H-pyran has a cavity and 6 hydroxyl groups that can form hydrogen bonds with water molecules, leading to its gelling properties. In addition, this compound is thermoreversible and can reversibly gel when heated or cooled. The gelation property of 2-(2-Bromoethoxy)tetrahydro-2H-pyran makes it a promising candidate for use in vaginal tablets, which could potentially lead to treatments for vaginal dryness and atrophy.</p>

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<p>Acetylcholine perchlorate is a pharmacological agent that is used to induce acetylcholine release by the brain. It can be used to study cholinergic mechanisms in the brain and bowel disease. Acetylcholine perchlorate has been shown to have physiological effects, such as increasing heart rate and blood pressure, which may be due to its ability to activate nicotinic acetylcholine receptors. Acetylcholine perchlorate has also been shown to cause chemiluminescence reactions that are similar to those seen in biological studies of acetylcholine receptors.</p>

<p>4-tert-Butyl-2,6-dimethylphenylsulfur Trifluoride is a chemical compound that is used as an intermediate in the synthesis of pharmaceuticals. It has been shown to be effective against 5-HT2C receptors and is used in the treatment of obesity. The mechanism of action for 4-tert-Butyl-2,6-dimethylphenylsulfur Trifluoride is not yet known but it may involve cleavage of amide bonds or stereoisomerism. 4-tert-Butyl-2,6-dimethylphenylsulfur Trifluoride has been synthesized by reacting hydrogen fluoride with sulfur trifluoride in the presence of a base.</p>

<p>7-Fluoro-2-methylquinoline is a multistep synthetic compound that belongs to the family of quinoxalines. It has been shown to have potent antibacterial activity against a wide range of bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) and Mycobacterium tuberculosis. 7-Fluoro-2-methylquinoline was developed as an analog of the natural product quinoxaline. The key step in its synthesis is the reaction between an aldehyde and hydroxyalkylating reagent in the presence of iron catalyst. This process results in the formation of functional groups such as hydroxyls, alkoxy, or halogens.</p>

<p>The heterocycle alpha-chloro-2-nitrobenzaldoxime is a functional group that can be oriented in two different ways. The diversity of the product arises from the fact that it is possible to create new functional groups by substitution on the benzene ring and on the nitrogen. Heterocyclization of alpha-chloro-2-nitrobenzaldoxime can be achieved by using other heterocycles such as isoxazoles, which are readily available in large quantities, as building blocks. This reaction can be catalyzed by reductive means with sodium borohydride and methanol.</p>

<p>LHRH (1-5) (free acid) trifluoroacetate salt is a synthetic hormone that is used in the treatment of prostate cancer. It inhibits the release of luteinizing hormone and follicle-stimulating hormone from the anterior pituitary gland, which suppresses testosterone production by the testes. LHRH (1-5) (free acid) trifluoroacetate salt is synthesized industrially using a liquid phase synthesis. The product may be recycled by returning it to the manufacturing process or using it as an additive for plastics or other industrial products. LHRH (1-5) (free acid) trifluoroacetate salt was shown to be active against tumor cells in culture and inhibited cell growth in culture. This drug has been shown to inhibit the production of nitric oxide, which may contribute to its anti-tumor activity. LHRH (1-5) (free acid)</p>

<p>5-Fluorohistidine is an organic compound with the formula CHFNO. It is a fluorinated derivative of histidine, and a precursor to histamine. 5-Fluorohistidine has been shown to be a potent thyrotropin-releasing hormone (TRH) analog, and is used in the synthesis of histamine. This compound has also been used as a tool for investigating the mechanism of TRH action by studying its stereoselective binding to protrusions from rat brain capillary endothelial cells. 5-Fluorohistidine has also been used as a microbial probe for detecting microbial protrusions from bacterial cells.</p>

<p>Undecafluorohexanoic acid is a perfluoroalkyl carboxylic acid that has been shown to disrupt steroidogenesis in vitro. It may be able to inhibit the transport of cholesterol, fats, and other lipids in cells, which causes disruption in steroidogenesis. This compound also has anti-cancer properties due to its ability to induce apoptosis and arrest cancer cell proliferation. Undecafluorohexanoic acid may also have developmental effects on animals because it can bind to estrogen receptors and disrupt the normal process of estrogen-mediated signaling pathways.</p>

<p>12-Fluorododecan-1-ol is a volatile chemical compound that is found in the exoskeleton of termites. It has been shown to be a major component of the termiticide, FluoroCitrate. 12-fluorododecan-1-ol can be used to control the growth of insect populations by interfering with their ability to synthesize fatty acids and alcohols. It also has an effect on protein synthesis and inhibits the activity of citrate synthase, which is an enzyme involved in glycolate metabolism. This compound is also toxic to some species of insects such as Rhinotermitidae. 12-fluorododecan-1-ol can be used as a marker for Reticulitermes flavipes (a type of wood eating cockroach) and it can be used to distinguish between different species or strains of termites.</p>

<p>2,3-Dichloropropionitrile is a synthetic chemical that is used for the chlorination of calcium carbonate. It is also used in the production of ester hydrochloride and acrylonitrile. The reaction vessel contains calcium carbonate and malonic acid, which are heated with hydrochloric acid. 2,3-Dichloropropionitrile is added to the reaction products to produce ester hydrochloride and acrylonitrile. The product can be isolated by adding hydrogen chloride to the reaction mixture.</p>

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<p>Methyl 2,5-dibromobenzoate is a cross-coupling reagent that is used to stabilize proteins. It is a hydrophobic compound that binds to the surface of proteins and prevents denaturation. Methyl 2,5-dibromobenzoate has been shown to be an effective binder for protein stabilization in a model system, where it was found to increase the reaction rate of Suzuki coupling reactions. This reagent can be used as a substitute for fluoroaromatic solvents in cross-coupling reactions.</p>

<p>COX1/2 inhibitor; nonsteroidal anti-inflammatory drug</p>

<p>3'-O-Benzyl-2'-Deoxy-5-Trifluoromethyluridine (BDBMU) is a pyrimidine derivative that can be used as an antiviral drug. It inhibits the synthesis of DNA and RNA by inhibiting viral polymerase. BDBMU is a prodrug of uracil, which is converted to the active compound in tissues. The benzoylation reaction produces a fluorine atom at C5, which increases its potency. This drug has been shown to have minimal toxicity in tumor cells and has been used for the treatment of leukemia and other cancers.</p>

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<p>Trityl chloride resin is a chemical compound that is used as a model system for the study of trifluoroacetic acid and its reactions. Trityl chloride resin is insoluble in water and has been used as a reaction solution for transfer reactions. It has been shown to be an effective ligand for many types of receptors, with binding constants ranging from 10 M-1 to 10 M-10. Trityl chloride resin can also be chiral, which means that it may exist in two forms that are mirror images of each other. The physiological effects of this compound are not well understood, but it has been shown to have an effect on coordination geometry.</p>

<p>(S)-(-)-6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid hydrochloride is a synthetic chiral compound that is used to study the role of glyoxylate in biochemical reactions. This drug is an enolate and alkylating agent that can react with nucleophiles such as amines and thiols. It has been shown to be effective against perchlorates by hydrolyzing them into chlorine and oxygen gas. This drug has also been shown to inhibit the growth of Rhodobacter sphaeroides by inhibiting glyoxylate metabolism.</p>

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<p>2-Bromopropionic acid benzyl ester is a synthetic compound with a molecular weight of 220.24 g/mol. It is soluble in organic solvents and has a hydroxyl group at its alpha position. 2-Bromopropionic acid benzyl ester is used in the synthesis of beta-cyclodextrin, which is an important biomaterial for drug delivery as well as other applications. 2-Bromopropionic acid benzyl ester also has antioxidant properties and can be used to treat leukemia cells by inhibiting the production of reactive oxygen species (ROS).</p>

<p>Germaniumtetrachloride (GeCl4) is a thermal expansion agent that is used in the production of boron nitride and zirconium oxide. It is also used as a catalyst for hydrochloric acid and hydroxyl group reactions. GeCl4 has carcinogenic potential, but this has not been confirmed in animal studies. GeCl4 is an effective solid catalyst for the reaction of hydrogen chloride with ethylene oxide to form polyethylene glycols. The mechanism of this reaction involves a substitution reaction between the chlorine ion and the hydroxyl group on the catalyst surface, forming chlorohydrocarbonate ions, which react with ethylene oxide to form polymer chains. This process can be carried out at room temperature or below, without using any solvents or catalysis promoters such as mercury or sulfur dioxide.</p>

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<p>H-Glu-Gly-Arg-chloromethylketone trifluoroacetate salt is an anticoagulant drug that prevents the formation of blood clots by inhibiting the enzyme thrombin. This drug is effective in enhancing blood flow and oxygen supply to the heart and other organs. H-Glu-Gly-Arg-chloromethylketone trifluoroacetate salt has been shown to have a positive effect on patients with congestive heart failure. It has also been used as an adjuvant therapy in bypassing procedures, where clotting occurs at the site of an artificial conduit placed in the body to allow blood flow between two points. In vitro studies have demonstrated that this drug inhibits protease activity, which may be due to its ability to inhibit fibrinogen and serine protease activity.</p>