Biochemicals and Reagents

<p>Applications Suberylglycine is one of the acylglycines, an important class of metabolites that have been used in the diagnosis of several inborn errors of metabolism (IEM).<br>References Costa, C., et al.: J. Pharmaceut. Biomed. Anal., 21, 1215 (2000), Garcia-Villoria, J., et al.: Clin. Biochem., 42, 2 (2009), Scalbert, A., et al.: Metabolomics, 5, 435 (2009),<br></p>

<p>Stability Hygroscopic<br>Applications ε-N-Deoxyfructosyllysine is a sugar-amino acid with potential antioxidant and anti-inflammatory properties.<br>References Kitts, D.D., et al.: J. Agri. Food. Chem., 60, 6718 (2012); Chalova, V.I., et al.: Food. Res. Intern., 45, 1044 (2012);<br></p>

<p>Applications Teneligliptin Hydrobromide (2:5) is a dipeptidyl peptidase-4 (DPP-4) inhibitor that is used to treat type 2 diabetes. It is eliminated via excretion, and has a half-life of 24.2 hours in the human body.<br>References Goda, M. &amp; Kadowaki, T.: Drugs Today, 49, 615 (2013); Kishimoto, M.: Diabetes Metab. Syndr. Obes., 6, 187 (2012)<br></p>

<p>Stability Light Sensitive<br>Applications A metabolite of Gentian Violet in seafood products. Dyes and metabolites, Environmental Testing<br>References Rushing, L., et al.: J. Chromatogr., 700, 223 (1997), Ohtsu, H., et al.: J. Med. Chem., 45, 5037 (2002), Yin, D., et al.: Mol. Pharmacol., 63, 211 (2003),<br></p>

<p>Stability Hygroscopic, Light Sensitive<br>Applications Rhodamine 110 is a fluorescent dye used as AP- and exopeptidase substrates for flow cytometric measurements. Dyes and metabolites.<br>References Ganesh S., et al.: Cytometry, 20, 334 (1995),<br></p>

<p>Stability Hygroscopic, Light Sensitive, Temperature Sensitive<br>Applications 10-Formyl-5,6,7,8-tetrahydro Folic Acid Disodium Salt is the disodium salt of F701085, which is a Folic Acid (F680300) derivative. Folic Acid is a vitamin needed to synthesize DNA, conduct DNA repair and methylate DNA, it also acts as a cofactor in biological reactions involving folate.10-Formyl-5,6,7,8-tetrahydro Folic Acid Disodium Salt is also used in the diagnosis and prevention and therapy of cerebral folate dificiency in relation to formation of folate receptor autoantibodies and treatment with reduced folate and antioxidants.<br>References Slieker, L.J., et al.: Mol. Pharmacol., 25, 294-302 (1984); Xu, L., et al.: Mol. Pharm., 7, 1311 (2010); Everette, J., et al.: J. Agric. Food Chem., 58, 8139 (2010); Alshatwi, A., et al.: Food, Chem., Toxicol., 48, 1881 (2010); McKay, D., et al.: Nut. J., 9 (2010)Ramaekers, WO 2006119589, (2006)<br></p>

<p>Applications Entecavir Monohydrate (cas# 209216-23-9) is a useful research chemical.<br></p>

<p>Applications 17α-Dydrogesterone is an isomer of Dydrogesterone (D826000), a synthetic progestin largely used in hormone therapy, on the central nervous system by studying two markers of the neuroendocrine function: the neurosteroid allopregnanolone and the opioid .beta.-endorphin. Progestogen.<br>References Bernardi, F., et al.: Eur. J. Endocrinol., 138, 316 (1998); Rupprecht, R., et al.: Steroids, 64, 83 (1999); Uzunova, V., et al.: Brain Res., 976, 1 (2003); Pluchino, N., et al.: J. Steroid Biochem. Mol. Biol., 102, 205 (2006)<br></p>

<p>Applications cis-7,10,13,16-Docosatetraenoic Acid Ethyl Ester-d5 is an isotopic analog of cis-7,10,13,16-Docosatetraenoic Acid Ethyl Ester. cis-7,10,13,16-Docosatetraenoic Acid Ethyl Ester is an ethyl analog of cis-7,10,13,16-Docosatetraenoic Acid (D494510). cis-7,10,13,16-Docosatetraenoic Acid has been identified as a protein kinase inhibitor, affecting serotonin levels in studies.<br>References Mirnikjoo, B. et al.: J. Biol. Chem., 276, 10888 (2001);<br></p>

<p>Applications Bodipy C12-Ceramide is a fluorescent substrate used for enzyme assays.<br>References Arbeloa, T.L., et al.: Chem. Phys. Lett., 299, 315 (1999); Drummen, G.P.C., et al.: Free Radical Biol. Med., 33, 473 (2002),<br></p>

<p>Stability Very Hygroscopic<br>Applications 1-O-Dimethoxytrityl-2-(N-Fmoc)-4-Aminobutyl)-1,3-propanediol is a useful reagent for the synthesis of acridine and​/or lipid containing oligodeoxyribonucleotides.<br>References Marasco, C. J., et al.: Tetra. Lett., 35, 3029 (1994)<br></p>

<p>Applications Azo Rubine is an synthetic red food dye and is used for the purposes where food is heat-treated after fermentation. Dyes and metabolites, Environmental Testing<br>References Abu, S., et al.: Sensor. Lett., 10, 894 (2012); Harp, B. P., et al.: Food. Add. Contamin., Chem. Anal. Control. Expo. Risk. Assess., 29, 886 (2012); Zohoori, S., et al.: Asian. J. Chem., 24. 1541 (2012);<br></p>

<p>Applications 10-Hydroxy-2-decenoic acid<br></p>